LOCUS       NM_001401195            5307 bp    mRNA    linear   ROD 25-MAR-2024
DEFINITION  Rattus norvegicus RAS protein activator like 2 (Rasal2), transcript
            variant 1, mRNA.
ACCESSION   NM_001401195 XM_017598812
VERSION     NM_001401195.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            On Feb 4, 2022 this sequence version replaced XM_017598812.2.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-863               JAXUCZ010000013.1  72101861-72102723   c
            864-991             JAXUCZ010000013.1  71975628-71975755   c
            992-1115            JAXUCZ010000013.1  71965084-71965207   c
            1116-1222           JAXUCZ010000013.1  71903050-71903156   c
            1223-1332           JAXUCZ010000013.1  71871102-71871211   c
            1333-1486           JAXUCZ010000013.1  71857557-71857710   c
            1487-1585           JAXUCZ010000013.1  71856212-71856310   c
            1586-2140           JAXUCZ010000013.1  71854253-71854807   c
            2141-2285           JAXUCZ010000013.1  71852766-71852910   c
            2286-2430           JAXUCZ010000013.1  71845929-71846073   c
            2431-2667           JAXUCZ010000013.1  71844972-71845208   c
            2668-2869           JAXUCZ010000013.1  71841216-71841417   c
            2870-3069           JAXUCZ010000013.1  71838624-71838823   c
            3070-3931           JAXUCZ010000013.1  71836969-71837830   c
            3932-4066           JAXUCZ010000013.1  71830162-71830296   c
            4067-4269           JAXUCZ010000013.1  71821071-71821273   c
            4270-4357           JAXUCZ010000013.1  71819666-71819753   c
            4358-5307           JAXUCZ010000013.1  71813455-71814404   c
FEATURES             Location/Qualifiers
     source          1..5307
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q22"
     gene            1..5307
                     /gene="Rasal2"
                     /note="RAS protein activator like 2"
                     /db_xref="GeneID:304893"
                     /db_xref="RGD:1307566"
     exon            1..863
                     /gene="Rasal2"
                     /inference="alignment:Splign:2.1.0"
     CDS             662..4522
                     /gene="Rasal2"
                     /note="isoform 1 is encoded by transcript variant 1; ras
                     GTPase-activating protein nGAP"
                     /codon_start=1
                     /product="ras GTPase-activating protein nGAP isoform 1"
                     /protein_id="NP_001388124.1"
                     /db_xref="GeneID:304893"
                     /db_xref="RGD:1307566"
                     /translation="MELSPSSGGAAEALSWPEMFSGLESDSPLPPEDLDAVVPVSGAV
                     AGGMLDRILLESVCQQQSWVRVFDVKGPPTHRLSCGQSPYTETTSWERKYCILTDSQL
                     VLLNKEKEIPVDGQDQQADSTKGRCLRRTVSVPSEGQFPEYPPEGTAKLEVPAERSPR
                     RRSISGTSTSEKPNSMDTANTSPFKVPGFFSKRLKGSIKRTKSQSKLDRNTSFRLPSL
                     RNADDRSRGLPKLKESRSHESLLSPCSAVECLDLGRGEPVSVKPLHSSILGQDFCFEV
                     TYLSGSKCFSCNSASERDKWMENLRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKKKY
                     FCELCLDDTLFARTTSKTKADNIFWGEHFEFYSLPPLHSITVHIYKDVEKKKKKDKNN
                     YVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGGPSIRIKSRFQTITILPMEQYKE
                     FAEFITSNYTMLCSVLEPVISVRNKEELACALVHILQSTGRAKDFLTDLVMSEVDRCG
                     EHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDPSKCSSSE
                     LTDHQSNLRMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDLSERLISASL
                     FLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMND
                     FLEHEWGGMKRFLLEISNPDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKGENS
                     FLQATVAKLGPLPRVLADITKSLTNPTPIQQQLRRFAEHSSSPNVSGSLSSGLQKIFE
                     DPTDSDLHKLKSPSQDNTDSYFRGKTLLLVQQASSQSMTYSEKDEKENSLPNGRSISL
                     MDLQDTHTAQVEHGSVMLDVPMRLAGSQLSITQVASIKQLRETQSTPQSAPQVRRPLH
                     PALNQPGSLQPLSFQNPVYHLNNPVPAMPKASADSSLENLSTASSRSQSNSEDFKLSG
                     PSNSSMEDFTKRSSHSEDFSRRHTAPDRHIPLALPRQNSTGQSQIRKLDQSGLGARAK
                     APPSLPHSASLRSTGSMSVASAALVAEPVQNGSRSRQQSSSSRESPVPKVRAIQRQQT
                     QQVQSPVDSATMSPVERTAAWVLNNGQYEEDVEETEQNQDEAKHAEKYEQEISKLKER
                     LRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRL
                     MAVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQVR
                     NGISPTNPTKLSITENGEFKNSSC"
     exon            864..991
                     /gene="Rasal2"
                     /inference="alignment:Splign:2.1.0"
     exon            992..1115
                     /gene="Rasal2"
                     /inference="alignment:Splign:2.1.0"
     exon            1116..1222
                     /gene="Rasal2"
                     /inference="alignment:Splign:2.1.0"
     exon            1223..1332
                     /gene="Rasal2"
                     /inference="alignment:Splign:2.1.0"
     exon            1333..1486
                     /gene="Rasal2"
                     /inference="alignment:Splign:2.1.0"
     exon            1487..1585
                     /gene="Rasal2"
                     /inference="alignment:Splign:2.1.0"
     exon            1586..2140
                     /gene="Rasal2"
                     /inference="alignment:Splign:2.1.0"
     exon            2141..2285
                     /gene="Rasal2"
                     /inference="alignment:Splign:2.1.0"
     exon            2286..2430
                     /gene="Rasal2"
                     /inference="alignment:Splign:2.1.0"
     exon            2431..2667
                     /gene="Rasal2"
                     /inference="alignment:Splign:2.1.0"
     exon            2668..2869
                     /gene="Rasal2"
                     /inference="alignment:Splign:2.1.0"
     exon            2870..3069
                     /gene="Rasal2"
                     /inference="alignment:Splign:2.1.0"
     exon            3070..3931
                     /gene="Rasal2"
                     /inference="alignment:Splign:2.1.0"
     exon            3932..4066
                     /gene="Rasal2"
                     /inference="alignment:Splign:2.1.0"
     exon            4067..4269
                     /gene="Rasal2"
                     /inference="alignment:Splign:2.1.0"
     exon            4270..4357
                     /gene="Rasal2"
                     /inference="alignment:Splign:2.1.0"
     exon            4358..5307
                     /gene="Rasal2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 accctgggat gccgcctgcc gccgccgcca gcgccgcggc tgccgggctt gtgggtttct
       61 cagaggagcg cgagccggag cccgagcagc ggccggagag gcggcctgag agttagcggg
      121 ccggtctgcg cgttccgcag gagcaagccc acgccaggcg gaaagaagcc gggccgggcc
      181 gggcgcgccc ctcaggctga gggagccggc gctttgagcc cctgaggcga cggcggcggg
      241 agccggtcag agggggcggc ccctggtggc gacgcccccg agcccagccc tgcctggccg
      301 cgctccatcc tcagccggag cccgggccgc ctgcgaacgc gcccgcgggg gctgagcagg
      361 gctgcgtggg ggcgggaggt gagcccgcgc tccccggtgc acagcgtccg ctccggacca
      421 gcacctgagc ccggacccgc ctccgctcca gaccacgctg gacccgcctc ccggtccggg
      481 tcccaccctc cgcttgcagg tgggctgcgg cgcccggccc ttgggcagtg ggcggcgggg
      541 aaggaggtga gcggcgtccg cgccggctgc cgttcgggtg ctggtggccg cgccgtcgtc
      601 cctttcccgc agccggggag cccgccctgc cgccgccgcc gcctgctccc tctgggacac
      661 catggagctt tccccgtcgt ccggaggagc cgcggaggcg ctgtcgtggc cggagatgtt
      721 ctcggggctg gagtccgact cgccgctgcc cccggaggat ctggacgcgg tcgtcccagt
      781 cagcggagca gtggccggtg gcatgctgga tcggatcctt ctggagtcag tgtgccagca
      841 gcagagctgg gtccgggtgt tcgatgtaaa aggcccacca acccaccgtc tgtcttgtgg
      901 tcagtcaccc tacactgaga caacatcatg ggagaggaaa tactgcatcc tcacagacag
      961 ccagttggtg ttgctcaaca aggagaagga gatacctgtg gatggacagg atcaacaggc
     1021 agattccacc aaagggcgat gcctgaggag aacggtcagt gttccttcag agggtcagtt
     1081 tccagagtac ccaccagagg gcaccgctaa actagaggta ccagcagaaa ggtccccccg
     1141 cagacggagc atctcaggga ccagcacatc agagaaaccc aactccatgg acactgcgaa
     1201 tacctctcct tttaaagtac caggcttctt cagcaagcgc ctgaaaggtt ccatcaagag
     1261 gaccaaaagc cagtcgaagc ttgacagaaa cacaagcttt cgacttccat ccctccgcaa
     1321 tgcagacgac aggtctcgtg gtctgcctaa actgaaggag tcacgttccc atgagtccct
     1381 gctgagccca tgcagtgcgg tggagtgttt ggatcttggg agaggagagc cggtctcagt
     1441 gaagccactg cacagtagca tccttggaca agacttctgc tttgaggtca cctacttaag
     1501 tggaagtaaa tgctttagct gtaactccgc ttcagagaga gataagtgga tggaaaacct
     1561 tcgaaggaca gttcagccaa ataaggataa ttgtagacga gctgaaaatg ttctccgttt
     1621 atggatcatt gaagccaagg accttgcccc taaaaaaaaa tatttctgcg aactgtgcct
     1681 tgatgatacc ctctttgctc gtacaaccag caagaccaaa gcagacaata ttttctgggg
     1741 tgaacatttt gaattctata gccttccgcc tcttcatagc atcaccgttc atatttataa
     1801 ggatgtggaa aaaaagaaaa aaaaggacaa gaataattat gtagggctag tcaacatccc
     1861 cactgccagt gtgactggtc gccagtttgt agaaaaatgg tacccagtga gtacacccac
     1921 acccaacaaa ggaaagacag gaggaccttc tattcggatt aagtcacgtt tccaaactat
     1981 caccatactg cctatggagc aatacaaaga gtttgcagaa ttcatcacca gcaactacac
     2041 catgctgtgc tctgttcttg agccagtaat tagtgtgcgg aataaggagg agttggcgtg
     2101 tgccttagta cacattcttc aaagtactgg cagagccaag gattttctga ctgacttagt
     2161 gatgtcagag gtagatcgtt gtggagagca tgatgtcttg atcttcagag aaaataccat
     2221 tgccactaaa tccattgagg aatacctcaa gttggtggga cagcagtatc ttcatgacgc
     2281 actcggggag ttcatcaaag ccttgtacga gtcagacgag aactgtgagg tggaccccag
     2341 caagtgctcg tccagcgagc tgacggacca tcagagcaac ctgaggatgt gctgcgagct
     2401 ggctttctgc aagatcatca actcatactg tgtcttccct cgtgagttga aagaagtgtt
     2461 tgcatcgtgg aagcagcagt gcctgaaccg aggcaagcaa gacctcagcg agcggctcat
     2521 cagtgcctca ttgtttctcc gttttctttg cccagccatt atgtctccca gtcttttcaa
     2581 cctgatgcag gagtatcctg atgaccgcac atctcggaca ctaactctta ttgccaaggt
     2641 cattcagaac ctggccaact ttgccaagtt tggtaacaaa gaggaataca tggcattcat
     2701 gaatgatttt ttagaacatg aatggggtgg aatgaagcgg ttccttttgg agatctcaaa
     2761 tcctgacacc atctcaaaca ccccaggctt cgatggctac attgatttgg gcagagagct
     2821 gtcagtttta cattccttgc tttgggaagt agtttcccaa ctggataagg gtgaaaattc
     2881 cttcctacag gcaactgtgg caaaattggg acctctccct cgtgttcttg ctgatattac
     2941 caagtctctg actaacccca cgccaataca gcagcagcta agacgcttcg ctgaacacag
     3001 ctccagtcca aatgtcagtg gaagcctctc ctctggactg cagaaaatat ttgaagaccc
     3061 cactgacagt gatttgcata aactaaagtc tccaagccag gataacacag acagctattt
     3121 cagaggaaag acgctgttgt tggttcagca agcctcctcc cagagcatga cgtactctga
     3181 aaaggatgaa aaggaaaaca gccttcctaa cggtcggagc atctccctca tggacctcca
     3241 ggacacccac actgctcagg tggagcatgg atctgtcatg cttgatgtgc ctatgcgcct
     3301 tgcaggaagc cagctctcta taacccaggt agctagcatc aaacagcttc gggaaaccca
     3361 gagcactccc cagagtgcac ctcaagtgag aagacccctg cacccagccc tgaaccagcc
     3421 aggaagtctc cagcccttgt cattccagaa ccctgtctat cacctcaaca acccagttcc
     3481 agcaatgcca aaggcctctg cggattccag tttggagaac ctaagcactg ccagttctcg
     3541 aagccaaagc aatagtgaag acttcaaact cagtgggccc agtaatagca gcatggaaga
     3601 tttcaccaaa agaagctcac acagtgagga cttctccagg cggcacactg caccagacag
     3661 acacatacct ctggctctgc cacgacaaaa tagtactggg cagtcccaaa tccgaaaact
     3721 ggaccaatct gggctgggtg cccgagccaa agcaccccct tctctgccac acagtgcttc
     3781 cttgcgtagc acggggagca tgtccgtggc atctgcagcc ctggtggctg aacctgtgca
     3841 gaatgggagc cggtccaggc agcagtcctc ttcctccaga gagagccctg tgcccaaagt
     3901 gagagcaatc cagagacaac agacacaaca ggttcagtca cctgtggact ctgccacaat
     3961 gtccccagta gaaaggacag cagcctgggt tctgaacaat ggacagtatg aagaggatgt
     4021 ggaagaaact gaacaaaatc aagatgaagc caagcatgct gaaaagtatg aacaagaaat
     4081 tagcaaactg aaggagcgtc tgcgggtgtc cagccggcgg ctggaggagt atgagcgccg
     4141 gctactggtt caggagcagc agatgcagaa gctgctgctg gagtacaagg cccggctgga
     4201 ggacagtgag gagcggctgc gcagacagca ggaggagaag gacagccaga tgaaaagcat
     4261 catcagcagg ctaatggctg tggaagagga gttaaagaag gaccacgctg agatgcaggc
     4321 agttattgat gcaaagcaga agataattga cgcacaggaa aagcggatcg tgtccctgga
     4381 ttcagccaac acgagactga tgagtgcgct gacacaggtg aaggagcggt acagcatgca
     4441 ggtccgcaat ggcatctctc ccaccaaccc caccaagctt tccatcacgg agaatggtga
     4501 attcaaaaat agcagctgct gatggccttc gtgacacaga ctgtgggagg aggcaggagg
     4561 aagtggccca gctctcctgt ccccagccct ttaaccctcc aggtttacag aatgttgctt
     4621 caaatggcga tgttgtgaga aactcttaca tgaagaaagg aaccttttct ttcagggctt
     4681 aaagcaaaga cttcaagttc aagttcgatg cttttcccca gtgtctctat gtacataggg
     4741 aatttagttc tgggccatgt acagaaatac cactgtaata taccaaaagg aagttaataa
     4801 tgtagattgc ctttttaatt attgctattt tattattgtt tttctcttat tgaaagcact
     4861 gcagttatta gtggaggaaa ggtaggagcc gagtgtgagt gaaaaatgag cctcttggtt
     4921 ctgtagctaa agtgtattgg ataggagcac gtggaatgca ataggacctt gtctgatgga
     4981 cgttttcagg gattcatctg ccagtttaaa gccccaccct gtccttacca ttaggaaaac
     5041 atgcaaatac caagatccat atgaaacaat aacttgccac tgtcaaccag gatgctcccg
     5101 gcagactgca gcctggtttg cagagccacc atttcagagg acacaggtaa acgtgactga
     5161 ctgtaccaaa accagactag gaaggatttc tgttaaactc ctctgtctat aatggacact
     5221 ttctgtctta gatgtgggac tttgattata cttcaacttt tttaactgct ctttagagtt
     5281 gacagaacta taaatactgt gtctcca
//
