LOCUS       XM_002727953            2836 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus RAS p21 protein activator 4 (Rasa4),
            transcript variant X1, mRNA.
ACCESSION   XM_002727953
VERSION     XM_002727953.5
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051347.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_002727953.6.
            
            On Jan 21, 2021 this sequence version replaced XM_002727953.4.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2836
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..2836
                     /gene="Rasa4"
                     /note="RAS p21 protein activator 4; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 28
                     ESTs, 1 long SRA read, 6 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 92 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:288589"
                     /db_xref="RGD:1565457"
     CDS             147..2558
                     /gene="Rasa4"
                     /codon_start=1
                     /product="ras GTPase-activating protein 4B isoform X1"
                     /protein_id="XP_002727999.1"
                     /db_xref="GeneID:288589"
                     /db_xref="RGD:1565457"
                     /translation="MAKRSSLSIRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTAT
                     VWKTLCPFWGEEYQVHLPPTFHMVAFYVMDEDALSRDDVIGKVCLTRDELTSHPKGFI
                     GWTHLVEVDPNEEVQGEIHLRLEVVPGLHASRLRCSVLEARDLAPKDRNGASDPFVRV
                     HYNGRTQETSVVKKSCYPRWNETFEFELEKGATEALLVEAWDWDLVSRNDFLGKVVVN
                     VQTLCSAQQEEGWFRLQPDQSKSRQGKGNLGSLQLEVRLRDETVLPSVYYQPLVQLLC
                     QEVKLGTQGPGQLIPVIEETTSAECRQEVATTLLKLFLGQGLAKDLLDLLFQLELGRT
                     SEANTLFRSNSLASKSMESFLKVAGMRYLHGILGPIIDRVFEEKKYVELDPSKVEVKD
                     VGCSGLHRPQTEAEVLEQSAQTLRAHLVALLSAICRSVRTCPAVVRATFRQLFRRVRE
                     RFPSAQHQNVPFIAVTSFLCLRFFSPAILSPKLFHLRERHADARTSRTLLLLAKAVQN
                     IGNMDTPVSRAKESWMEPLQPTVRQGVVQLKDFITKLVDIEEKEELDLQRALNLQAPP
                     VKEGPLFIHRTKGKGPLASSSFKKLYFSLTTEALSFAKTSSSKKSVFIKLASIRAAEK
                     VEEKSFGSSHVMQVIYSDDVGRAQTVYLQCKCVNELNQWLSALRKVITNNASLLGSYH
                     PGVFRGDKWSCCHQKEKTDLGCDKTHSRVTLQEWNDPLDHDLEAQLIYRHLLGVEAAL
                     REKHQLLSRATEEAGTSSTGRGGAPEDSLAQLLRVLRDLREAHSSSLASSPSREPRHL
                     LELQT"
ORIGIN      
        1 gcggagatcc ctccgcccca gcgctcccct ctctggcctc cgcacccgcc tgcttgcagc
       61 gccactctca ctgccccctc ccactctcgg gaggggaccc aggcgtccga accgctccct
      121 acaggcctcc acgtcgccga cccgcaatgg ccaagcgcag ttcgctgtcc atccgaatcg
      181 tagaagggaa aaatctgccc gccaaggaca tcacgggcag cagcgacccc tactgcatcg
      241 tgaaggtgga caatgaacca atcatcagga cagccactgt gtggaagacc ctgtgcccat
      301 tctggggtga agagtaccaa gtacatttac cccccacatt ccacatggtg gccttctatg
      361 ttatggatga agacgccctt agccgggacg atgtgatcgg gaaggtctgc ctcacaaggg
      421 atgagctaac ctctcaccca aagggattca tcggatggac ccacctggtg gaggtggacc
      481 cgaacgagga ggtgcagggt gagatccacc tgcgtctgga ggtggtgcca gggctccacg
      541 ccagccggct gcgctgctct gtgcttgagg ccagggactt agcaccaaaa gaccggaatg
      601 gcgcatctga cccttttgtc cgagtgcact acaatggccg gacccaggag acctcggtgg
      661 tgaaaaaatc ctgctaccca cgctggaatg agacatttga gtttgagctg gaaaagggag
      721 ccacagaagc actgctggtg gaggcctggg actgggatct tgttagccgg aatgactttc
      781 taggcaaagt ggtagtcaat gtccagacac tgtgttcagc ccagcaggaa gagggctggt
      841 tccggctgca gcccgaccag tccaaaagcc gtcaaggcaa gggcaacctg ggctccttgc
      901 agttggaggt gcggctgcgg gatgagacag tgctgccgtc tgtctactac cagcctctgg
      961 tacagctgct gtgccaggag gtgaagctgg gcacccaggg cccaggacag ctgattcctg
     1021 tcattgagga gacaaccagt gctgagtgtc gccaggaagt ggccaccacc ctgcttaagc
     1081 tcttcctggg gcaggggctg gccaaggacc ttctggacct gctctttcag ctggagctgg
     1141 gccgcaccag tgaggccaac accctcttcc ggagcaattc tctggcctca aagtccatgg
     1201 aatcctttct gaaggtggca gggatgcgct atctgcatgg catcctgggc cccatcattg
     1261 acagagtgtt cgaggagaag aagtatgtgg agctggaccc cagcaaagtg gaagttaagg
     1321 atgtagggtg ctctgggctg caccgcccac agacggaggc tgaagtgtta gagcagagcg
     1381 cacagacgct gcgtgcccac ttggtggcgc tgctgagcgc catatgccgc tcggttcgca
     1441 cctgtccagc tgtggtccgc gccacttttc ggcagctgtt caggcgcgtg cgggagcgct
     1501 tccccagcgc ccagcatcag aacgtaccat tcatcgcggt caccagcttc ctgtgcctgc
     1561 gcttcttctc tcccgccatc ctgtcgccca agctcttcca cctgcgagag cggcatgcag
     1621 atgctcgcac cagtcgcaca ctacttctgc tggccaaggc ggtccagaac ataggcaata
     1681 tggacacacc ggtctccagg gccaaagagt cgtggatgga accactacag cctactgtgc
     1741 gccagggtgt ggtgcagctg aaggacttca ttacgaagct cgtggacata gaagaaaagg
     1801 aagagctgga cctgcagcgg gcattgaact tgcaggctcc gcctgtgaag gagggaccac
     1861 tgtttatcca cagaaccaaa ggcaaaggcc ctcttgcgtc ctcctcgttc aagaaactct
     1921 acttctctct taccactgaa gccctcagct tcgccaagac atccagctcc aagaaaagtg
     1981 tcttcatcaa gctggccagc atccgggctg cggagaaggt ggaggaaaag agcttcggca
     2041 gctcccacgt catgcaggtc atctactcag acgatgttgg ccgggcccag actgtctacc
     2101 tgcagtgcaa gtgtgtgaac gagttgaacc agtggctatc tgcactgcgc aaagtgatta
     2161 ccaacaatgc cagcctcctg ggctcctacc accctggcgt cttccgtggg gacaagtgga
     2221 gctgctgtca ccagaaggaa aagacagatc tgggatgtga caagacccat tctcgggtga
     2281 ccctgcagga gtggaatgac ccactggacc atgaccttga ggcgcagctc atctacagac
     2341 acctgctagg agtagaggct gctcttcggg aaaagcacca gctcctgagc cgggcaacag
     2401 aagaagcagg cacctcatcc acaggccgtg gcggagctcc tgaggactca ctggcccagc
     2461 tgctccgagt gctgcgagac cttcgagaag cccacagctc cagcctggct agctcgccat
     2521 ccagagagcc ccgtcacctc ctagagctac agacatgagg tgtccgtgag gcgtccactg
     2581 agcctgtcag gtgtctggag atccttaacg tgctcaggac cctgtcccag tcaactgttc
     2641 tggggagggt tgtgactcaa catggtcttc tccatgtctt tgtgggacaa ctgtggcacc
     2701 tgcttctttg ggagacccga ctattcctgc agtccctgtg gcccagatcc ttcacccagg
     2761 agaccaggct gtccacctca cactgctttg ccactgtctg gcttcctagg tcattaataa
     2821 acctgctgtg actgct
//
