LOCUS       NM_001106643            1886 bp    mRNA    linear   ROD 20-SEP-2024
DEFINITION  Rattus norvegicus arginyl-tRNA synthetase 2, mitochondrial (Rars2),
            mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001106643 XM_001065097 XM_216367
VERSION     NM_001106643.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1886)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 1886)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC158744.1.
            
            On Jan 27, 2008 this sequence version replaced NM_001106643.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158744.1, SRR8487231.114726.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132294, SAMD00132300
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1886
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q21"
     gene            1..1886
                     /gene="Rars2"
                     /gene_synonym="Rarsl"
                     /note="arginyl-tRNA synthetase 2, mitochondrial"
                     /db_xref="GeneID:297969"
                     /db_xref="RGD:1305419"
     exon            1..60
                     /gene="Rars2"
                     /gene_synonym="Rarsl"
                     /inference="alignment:Splign:2.1.0"
     CDS             25..1761
                     /gene="Rars2"
                     /gene_synonym="Rarsl"
                     /EC_number="6.1.1.19"
                     /note="probable arginyl-tRNA synthetase, mitochondrial;
                     arginyl-tRNA synthetase-like"
                     /codon_start=1
                     /product="probable arginine--tRNA ligase, mitochondrial"
                     /protein_id="NP_001100113.1"
                     /db_xref="GeneID:297969"
                     /db_xref="RGD:1305419"
                     /translation="MACGFRRSIACQLSRVLALPPESLIKSISAVPVSKKEEVADFQL
                     SVDSLLENNSHKSQLDTQDQAQRLAEKLKCDTVVTAISAGPRTLNFKINRALLTKAVL
                     QQVTEDGSKYGLKSELFSDLPQKRIVVEFSSPNIAKKFHVGHLRSTIIGNFIANLKEA
                     LGHQVTRINYIGDWGMQFGLLGTGFQLFGYEEKLQANPLQHLFDVYVQVNKEATDDKN
                     VTKLAHEFFHRLELGDTQALALWQRFRDLSIEEYTQIYKRLGIYFDEYSGESFYREKS
                     QDVLKLLDSKGLLQKTAKGNVVVDVSETGDLSSVCTVMRSDGTSLYATRDLAAAIHRK
                     DKYNFDTMIYVADKGQKRHFQQVFQMLKIMGHEWAERCQHVPFGIVKGMKTRRGEVTF
                     LEDVLNEVQSRMLQNMASIKTTKKMENPRETAEKVGLAALIIQDFRGLLLSDYQFSWD
                     RVFQSRGDTGVFLQYTHARLCSLEETFGCGYLNDFNVACLQEPQSVSILQHLLRFDEV
                     LYTASQDLQPKHIVSYLLTLSHLAAVAHKTLQVKDSPPEVAGARLHLFKAVRSVLANG
                     MKLLGITPVCKM"
     exon            61..134
                     /gene="Rars2"
                     /gene_synonym="Rarsl"
                     /inference="alignment:Splign:2.1.0"
     exon            135..237
                     /gene="Rars2"
                     /gene_synonym="Rarsl"
                     /inference="alignment:Splign:2.1.0"
     exon            238..321
                     /gene="Rars2"
                     /gene_synonym="Rarsl"
                     /inference="alignment:Splign:2.1.0"
     exon            322..419
                     /gene="Rars2"
                     /gene_synonym="Rarsl"
                     /inference="alignment:Splign:2.1.0"
     exon            420..475
                     /gene="Rars2"
                     /gene_synonym="Rarsl"
                     /inference="alignment:Splign:2.1.0"
     exon            476..559
                     /gene="Rars2"
                     /gene_synonym="Rarsl"
                     /inference="alignment:Splign:2.1.0"
     exon            560..636
                     /gene="Rars2"
                     /gene_synonym="Rarsl"
                     /inference="alignment:Splign:2.1.0"
     exon            637..795
                     /gene="Rars2"
                     /gene_synonym="Rarsl"
                     /inference="alignment:Splign:2.1.0"
     exon            796..902
                     /gene="Rars2"
                     /gene_synonym="Rarsl"
                     /inference="alignment:Splign:2.1.0"
     exon            903..998
                     /gene="Rars2"
                     /gene_synonym="Rarsl"
                     /inference="alignment:Splign:2.1.0"
     exon            999..1059
                     /gene="Rars2"
                     /gene_synonym="Rarsl"
                     /inference="alignment:Splign:2.1.0"
     exon            1060..1136
                     /gene="Rars2"
                     /gene_synonym="Rarsl"
                     /inference="alignment:Splign:2.1.0"
     exon            1137..1261
                     /gene="Rars2"
                     /gene_synonym="Rarsl"
                     /inference="alignment:Splign:2.1.0"
     exon            1262..1329
                     /gene="Rars2"
                     /gene_synonym="Rarsl"
                     /inference="alignment:Splign:2.1.0"
     exon            1330..1439
                     /gene="Rars2"
                     /gene_synonym="Rarsl"
                     /inference="alignment:Splign:2.1.0"
     exon            1440..1535
                     /gene="Rars2"
                     /gene_synonym="Rarsl"
                     /inference="alignment:Splign:2.1.0"
     exon            1536..1610
                     /gene="Rars2"
                     /gene_synonym="Rarsl"
                     /inference="alignment:Splign:2.1.0"
     exon            1611..1674
                     /gene="Rars2"
                     /gene_synonym="Rarsl"
                     /inference="alignment:Splign:2.1.0"
     exon            1675..1859
                     /gene="Rars2"
                     /gene_synonym="Rarsl"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggggcttg cgggaaaagg aggcatggcg tgtggctttc gtaggtcgat tgcctgtcag
       61 ctttccagag tattggctct tccaccagaa agcttgatta agtctatatc ggctgttcca
      121 gtttcaaaga aagaagaagt ggcagatttt cagctttctg tggattcctt gctagaaaac
      181 aacagtcaca agtcacagct agacactcaa gatcaagccc agagactggc agagaagctt
      241 aagtgtgata cagtggtgac agccatcagt gctggtccaa ggactctaaa tttcaaaata
      301 aacagagcat tattaacaaa ggcagtgttg caacaagtaa ctgaagatgg ttcaaaatac
      361 gggttaaaaa gtgagctttt ctcagatctt ccccagaaga ggattgtggt tgaattcagc
      421 tcacctaata ttgccaaaaa atttcatgtt ggtcatttgc gctccaccat cataggaaat
      481 ttcatagcga atctaaaaga agctttagga caccaagtga caagaataaa ttacattggc
      541 gattggggca tgcagtttgg tctgctggga actggtttcc agctgtttgg ctatgaagag
      601 aaactccagg ccaatccttt acagcatctc tttgatgttt atgtacaagt taataaagaa
      661 gcaactgatg ataaaaatgt aactaagttg gcacacgagt tcttccaccg actagaactg
      721 ggtgacacgc aggccctggc cctgtggcag agattccggg acttgagcat tgaagaatac
      781 acccagattt acaagcgtct tggaatatac tttgatgaat attcaggaga atcattttat
      841 cgtgaaaaat ctcaagatgt cttaaagttg cttgacagca aaggacttct acagaaaaca
      901 gcaaagggga atgtagtagt agatgtctct gagactggcg acctctcttc tgtctgcacc
      961 gtgatgcgaa gtgatggaac gtctctctat gcaaccaggg accttgcagc tgccatacat
     1021 cgcaaggaca agtacaactt tgacacaatg atttatgttg cagataaagg gcaaaaaagg
     1081 catttccagc aagtattcca aatgctgaag atcatgggac atgaatgggc agaaaggtgc
     1141 cagcatgtgc ccttcgggat agtaaaggga atgaagactc gaagaggaga agtcactttt
     1201 ctggaagatg tcttaaatga agttcaatca aggatgttac agaacatggc ttccattaag
     1261 acaaccaaaa aaatggagaa ccctcgggag accgcagaga aggtggggct ggcagctctc
     1321 atcatccagg acttcagagg cttgctctta tccgactatc agttcagttg ggatcgtgtt
     1381 ttccagagtc gtggggacac cggagtcttc ctgcagtaca cccacgcccg cctctgtagt
     1441 ctggaagaga cttttggatg tgggtatctc aatgacttca atgttgcttg tttacaagag
     1501 ccacagtctg tttcaattct ccagcatctt ctcaggttcg atgaggtact ttatacagca
     1561 tctcaggacc tgcagccgaa gcacatcgtt agttacctct taaccctgag tcaccttgca
     1621 gctgtggcac ataaaacact ccaagtgaaa gacagtcctc ctgaagtggc tggggccaga
     1681 cttcaccttt tcaaagctgt ccgttctgtc ttagccaatg gaatgaaact tcttggaatt
     1741 acacctgtat gtaaaatgta atttctagat aaagtatgtt ttttatgcaa atgagttcta
     1801 attgttatca gatgccttgc tattcagaat agaatttaaa gtattattct gtcccggaaa
     1861 aaaaaaaaaa aaaaaaaaaa aaaaaa
//
