LOCUS       NP_001102268            1266 aa            linear   ROD 31-MAR-2024
DEFINITION  ras-associated and pleckstrin homology domains-containing protein 1
            [Rattus norvegicus].
ACCESSION   NP_001102268 XP_001070281 XP_343580
VERSION     NP_001102268.2
DBSOURCE    REFSEQ: accession NM_001108798.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 1266)
  AUTHORS   Michael,M., Vehlow,A., Navarro,C. and Krause,M.
  TITLE     c-Abl, Lamellipodin, and Ena/VASP proteins cooperate in dorsal
            ruffling of fibroblasts and axonal morphogenesis
  JOURNAL   Curr Biol 20 (9), 783-791 (2010)
   PUBMED   20417104
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Jul 27, 2011 this sequence version replaced NP_001102268.1.
            
            Sequence Note: This RefSeq record was created from genomic sequence
            data. There are no rat transcripts representing this gene; the
            genomic coordinates used for the transcript record were predicted
            based on mouse transcript alignments and on full-length homologous
            protein alignment with mouse NP_001230057.1 and human NP_998754.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1266
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q32"
     Protein         1..1266
                     /product="ras-associated and pleckstrin homology
                     domains-containing protein 1"
                     /calculated_mol_wt=136588
     Region          268..357
                     /region_name="RA_MRL_Lpd"
                     /note="Ras-associating (RA) domain found in the adapter
                     protein lamellipodin (Lpd); cd16136"
                     /db_xref="CDD:340553"
     Site            order(275,280..287,303..306,321,339..340,343)
                     /site_type="other"
                     /note="RA-PH-RAP1 interaction site [polypeptide binding]"
                     /db_xref="CDD:340553"
     Region          393..515
                     /region_name="PH_APBB1IP"
                     /note="Amyloid beta (A4) Precursor protein-Binding, family
                     B, member 1 Interacting Protein pleckstrin homology (PH)
                     domain; cd01259"
                     /db_xref="CDD:269961"
     CDS             1..1266
                     /gene="Raph1"
                     /coded_by="NM_001108798.2:200..4000"
                     /db_xref="GeneID:363239"
                     /db_xref="RGD:1308387"
ORIGIN      
        1 meqlsdeeid hgaeedsdke dqdldkmfga wlgeldrltq sldsdkpkep vkrsplrqet
       61 nmanfsyrfs iynlnealnq getvdldalm adlcsieqel ssvgsgnskr qvtepkvaqk
      121 lpasrhtskh gtlrgvssss trttrpphan ysldditaql eqaslsmdea aqqsavedak
      181 ppatnqhrrt asagtvsdae vrsvsnssrs sitsaassmd sldidkvtrp qeldltahqg
      241 kpiteeeqaa klkaekirva lekikeaqvk klvirvhmsd dssktmmvde rqtvrqvldn
      301 lmdkshcgys ldwslvetis elqmerifed henlvenlln wtrdsqnkli fmeriekyal
      361 fknpqnyllg kketaemadr nkevlleecf cgssvtvpei egvlwlkddg kkswkkryfl
      421 lrasgiyyvp kgkakvsrdl vcflqldhvn vyygqdyrnk ykaptdccla lkhpqiqkks
      481 qyikylccdd artlhqwvng iriakygkql ytnyqealkr tesaydwtsl ssssiksgss
      541 sssipesqsn hsnqsdsgvs dtlpsghirs qstvssifse awkrgtqlee sskarmesmn
      601 rsytslmppl spqtkiitpy tasqpspplp pppppppppp pppppppppl psqsapssgs
      661 aatmfvkyst itrlqnaaqh sgtlfkspap samqplplas qskaqivvpp ngvipppppp
      721 pppptpgsam aqlkpvpcap slpqfspqpp plkihqvqhl pqaapptppa aplipatvpp
      781 qappkplvti ppsastkmvs pvvaqavppt pappvpptkk qpvfpvship ptppvqptph
      841 ppptlpkqqs fgvkpppspl spvpsvvkqm asqfpppptp ppvdsqplkp lpasvtpqsp
      901 pavkakpkwq pssipapspd fpppppessl vfppppppap vppppppppp ppppppvspm
      961 asptpdkggs pgkktskmss pggkkppptp qrnssiksgs caehpepkrp svdslvskfa
     1021 ppaesgspsk etppppaapp kpgklhlsgv nlpgihqqgi lsakpsvlsg rgkdavvefp
     1081 sppsdsdfpp pppeielplp pieipavfsg ntspkvavvn pqpqlwskts vkkappptrp
     1141 krndstrltq adiseqpamt tvvpqvptsp ksslsvqpgf ladlnrtlqr ksitrhgsls
     1201 ssrmsraept atmddmalpp pppellsdqq kagfggshis gyatlrrgpp pappkrdqnt
     1261 klsrdw
//
