LOCUS       XM_008768202            4144 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus Rap guanine nucleotide exchange factor
            like 1 (Rapgefl1), transcript variant X1, mRNA.
ACCESSION   XM_008768202
VERSION     XM_008768202.3
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051345.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 3, 2024 this sequence was replaced by
            NM_001427833.1.
            
            On Jan 21, 2021 this sequence version replaced XM_008768202.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4144
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4144
                     /gene="Rapgefl1"
                     /note="Rap guanine nucleotide exchange factor like 1;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 1 mRNA, 22 ESTs, 8 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 63 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:303515"
                     /db_xref="RGD:1563269"
     CDS             380..2371
                     /gene="Rapgefl1"
                     /codon_start=1
                     /product="rap guanine nucleotide exchange factor-like 1
                     isoform X1"
                     /protein_id="XP_008766424.1"
                     /db_xref="GeneID:303515"
                     /db_xref="RGD:1563269"
                     /translation="MKPLEKFLKKQTSQLAGRAVAGGPGGGPGCCGGPGGGGGSGGGG
                     GPTGGLRPLQRRQSVSRLLLPAFLREHPTDPGLEPPVEEEGGEPLGVSEEPGSGGPCW
                     LQLEEVPGPGPIGSGVPLRSPSSYSSDELSPGEPLASPPWAPLGAPERPEHLLNRVLE
                     RLAGGTTRDSSSASDILLDDIVLTHSLFLPTEKFLQELHQYFVQSKNVEGPEGLGRKQ
                     ACLALLLHFLDTYQGLLQEEEGAGHIIKELYLLIMKDESLYQDLREDTLRLHQLVETV
                     ELKIPEESQPPSKQVKPLFRHFRRIDSCLQTRVAFRGSDEIFCRVYMPDHSYVTIRSR
                     LSASVQDILGSVTEKLQYSEEPAEREDALILVAVASSGEKVLLQPTEDCVFTTLGINS
                     HLFACTRDSYEALVPLPEEIQASPGDTEIHRVEPEDVANHLTAFHWELFRCVHELEFV
                     DYVFHGERGRRETANLELLLQRCSEVTHWVATEVLLCEAPGKRVQLLKKFIKIAAICK
                     QNQDLLSFYAVVMGLDNAAVSRLRLTWEKLPGKFKNLFRKFESLTDPCRNHKSYREVI
                     SKMKPPLIPFVPLILKDLTFLHEGSKTLVDGLVNIEKLHSVAEKVRTIRKYRSRPLCL
                     DMEASPHHLQTKAYVRQFQVIDNQNHLFELSYKLEANSQ"
ORIGIN      
        1 tctgccacct tccccggggc caggagcgca gccgccgccg cgtcctcagc cttgcgctcc
       61 gcccgctgcc tctgtcgctt cggcccggcc ccggaggact gagacgggga caccagcccc
      121 tcagcctgcc aacccttcgg ccgcagccag catggggggc cgctgagagc cagctcctct
      181 tccctctggc acctcccccg gccactggcc actggactct ggccagcgag gctcggccac
      241 ctctcgctcg cagtccgacg cctggcacag ccctcggctc tgctcccccg gctctgagca
      301 tcgtgtcccc gcctcccccc gcccgcgcct gggacacctg ggtcccccgg cggccccaag
      361 gagaggggcg ggggggggca tgaagccact ggagaaattt ttgaagaagc agacgtcgca
      421 actggcgggg cgagcggtgg ctggaggtcc cggcgggggt ccgggttgct gcggagggcc
      481 tggagggggt gggggctctg gtgggggcgg cggtccgacc gggggactgc ggccactgca
      541 gcggcgtcag agcgtgtctc gcctgctgct cccagctttc ctccgagaac acccaaccga
      601 ccccgggctg gagccgcccg ttgaggagga agggggagag ccattagggg tctctgagga
      661 gccaggcagt ggggggccct gttggctgca gctagaggag gttcctgggc ctgggccgat
      721 aggatccggg gtgcccctgc gctctccttc ctcgtactcc tcagatgagc tatcccccgg
      781 cgaacccctg gcttcaccac cctgggcccc cctgggcgcc cccgagcggc cagagcatct
      841 tctgaaccgg gttctggagc gcctggctgg aggaaccacc agggacagca gcagcgcctc
      901 agatattctc cttgatgaca ttgtcctcac ccattccctc ttcctgccaa cagagaagtt
      961 tctacaggag ttacaccagt actttgttca gtcaaagaat gtggagggtc cagaggggct
     1021 gggccggaag caagcctgtc ttgcgctact cctccatttc ttggatacct accaaggact
     1081 actgcaagag gaagaagggg ccggtcacat tatcaaggaa ctgtatctac taattatgaa
     1141 ggatgagtcc ctttaccaag acctccgaga ggacacactg aggctgcacc agctggtgga
     1201 gacagtggag ctaaaaattc cagaggagag ccagccaccc agcaagcagg tgaagccgct
     1261 cttccgacac ttccgccgga tagattcctg tctgcagacc cgagtggcat tcaggggctc
     1321 cgatgagatc ttctgccgag tctacatgcc tgatcactct tacgtgacca tacgcagtcg
     1381 tctgtcagca tctgtgcaag acatcctggg ctccgtgaca gagaagctgc agtactcgga
     1441 ggaacccgcg gagcgtgagg atgccctcat cctcgtcgct gtggcttcct ctggagagaa
     1501 ggtcctcctc cagccaacgg aggactgcgt cttcaccacg ctgggcatca acagccacct
     1561 gtttgcctgt acccgggaca gctatgaggc cctagtaccc cttcctgagg agatccaggc
     1621 ctccccggga gacacagaga tccaccgggt ggagcctgaa gatgtggcca atcatctgac
     1681 tgctttccac tgggaactgt tccgatgtgt gcacgagttg gagttcgtgg actatgtgtt
     1741 ccacggcgag cgcggccgcc gagagacagc caatctggag ttgctgctgc agcgctgcag
     1801 cgaggtcact cactgggtgg ccaccgaggt gctgctgtgt gaggccccgg gcaagcgtgt
     1861 ccagctgctc aagaagttca tcaagatcgc agccatatgc aaacagaacc aggacctgct
     1921 gtccttctat gctgtggtga tggggctgga caatgctgct gtcagccgcc taaggctcac
     1981 ttgggagaag ctaccaggga aattcaagaa cctgttccgt aaatttgaga gcttgacgga
     2041 cccctgccgg aaccataaaa gctacagaga agtcatctcc aaaatgaagc cccctctgat
     2101 tccgttcgtg cccctgatcc tcaaagatct gaccttccta catgagggga gcaagaccct
     2161 cgtggatggt ctggtgaaca ttgagaagct gcattcagta gctgagaaag tgaggacaat
     2221 ccgaaaatac cggagccggc ccctctgtct agacatggag gcctccccgc atcacctcca
     2281 gaccaaggca tatgtgcgcc agttccaggt catcgacaac cagaaccacc tctttgagct
     2341 ctcctacaag ttggaggcca atagtcagtg agagcgaggg ggcctggctg cccccaccta
     2401 agtccttggc acccggcact caagcacttt gcacgatgcc ctcaacaacc tacgttggag
     2461 accttctccc tggagcaatg tcctgtccta caaggaggaa ctgggttggc ctaccaggac
     2521 gtgtcataag cctgtcatcc tgctgaggtc taaccacact caagctactc tcctggtgtc
     2581 tggcctggct gggcaaggga tggggaggag caaccctctg ctctctgggt gaggtctatt
     2641 ccagagatga ttctggtctc cacttcccac tcgggaagga agcactcgct cccagatcac
     2701 agctgtggta tgggaggtac tgggaggtac tcgaagtctt cttccctgac agctgtttca
     2761 ctgatcccta tacaccccct agaatagtga gtgagtgtgt gtgtgtgtgt gcgcgcgctg
     2821 tgcgatgagc atgtcccctt ttagggcgca ggactgcgtc tgataatgta gggagagagt
     2881 cacaagtgtt ttgaggatgc cttccgtttg gtgctaccct tgttggctat gtctccaatc
     2941 actccctgcc caaccccacc cactgtccca cacaggaaga ctgtgggcca acctgttcct
     3001 gaaggcagga ggtatcagta ggcagaagag ttacccgtca gtcccgacaa atcccccacc
     3061 caagcttccc caagatctct ggatatgtgt cagtgagagg ctaaaagatg ctcagggaaa
     3121 cgcaggccta agctgcctct gggtccctgc ctctgccttg tactgggtgg gatgcagtgg
     3181 tatccagagc caggggtgcc tgttccccat acctctccac tttggggggg tttctctctg
     3241 ctaaggagga agttgtcatc ttccttctgg tcagtgtctg ctaccaacca tcgtctgcct
     3301 gtctgtctgc ctgcctgcct gcctgcctgt cttcatcccc ctttgtcttt ctatagagcc
     3361 tagggtggat ctcagtacct agggcagacc gctcctccct gcgtggtgag aagagaggct
     3421 gcagcagcta taaagatgga gctgggctct agtagggcct tcattacctg tcccatctct
     3481 tcctccatgg ctgaggggtt gcaggggctc ctggcagcta ctgcgtgcag tttcctggca
     3541 cagcctcata ctgtccttcc tggcccttct gaagaggtag caatggccgc cgaagccgtg
     3601 aagtcagctg cagcccctgc tctaggagtg tatatatttt ttacccaaag ctctggaatt
     3661 gtacatttat tttttaaaac ccaaagaggg caagaatctt gtaccatatg taaacactgt
     3721 attataggtt atgttgtaca gtccttttat acagcagttc ctgtgaaaat atccatcatg
     3781 ccatacgact tctccagccc acagtggtga tggtgaccat gccacccccg ggcccataat
     3841 ggcgatagtg actgatcctc tcccatcttc tgctgcatcc ctgcaactgc agctcagact
     3901 tctgcccctc tctgtagccc ttcatcagcc ttctctagtt ccctagccct ccacaaatac
     3961 cgcctccccc agcccttggc tgctgcttgc ctctggtcgt gatgcttgcc ccactggttc
     4021 tcaggggccc catcccccaa ccccgtagct ttaacagagt gaaccgtgta cgttgtacag
     4081 gcctagttgt cattgcagaa actgctcaat agaaaaaaaa aatacactaa tgtctatgaa
     4141 tcaa
//
