LOCUS       NP_001120923             119 aa            linear   ROD 20-MAR-2023
DEFINITION  RNA guanine-N7 methyltransferase activating subunit [Rattus
            norvegicus].
ACCESSION   NP_001120923 XP_001060165 XP_001062455 XP_001062519 XP_214983
VERSION     NP_001120923.1
DBSOURCE    REFSEQ: accession NM_001127451.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 119)
  AUTHORS   Varshney D, Petit AP, Bueren-Calabuig JA, Jansen C, Fletcher DA,
            Peggie M, Weidlich S, Scullion P, Pisliakov AV and Cowling VH.
  TITLE     Molecular basis of RNA guanine-7 methyltransferase (RNMT)
            activation by RAM
  JOURNAL   Nucleic Acids Res 44 (21), 10423-10436 (2016)
   PUBMED   27422871
REFERENCE   2  (residues 1 to 119)
  AUTHORS   Gonatopoulos-Pournatzis T and Cowling VH.
  TITLE     Cap-binding complex (CBC)
  JOURNAL   Biochem J 457 (2), 231-242 (2014)
   PUBMED   24354960
  REMARK    Review article
            Erratum:[Biochem J. 2014 Feb 15;458(1):185]
REFERENCE   3  (residues 1 to 119)
  AUTHORS   Baltz AG, Munschauer M, Schwanhausser B, Vasile A, Murakawa Y,
            Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E,
            Bonneau R, Selbach M, Dieterich C and Landthaler M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (residues 1 to 119)
  AUTHORS   Gonatopoulos-Pournatzis T, Dunn S, Bounds R and Cowling VH.
  TITLE     RAM/Fam103a1 is required for mRNA cap methylation
  JOURNAL   Mol Cell 44 (4), 585-596 (2011)
   PUBMED   22099306
REFERENCE   5  (residues 1 to 119)
  AUTHORS   Farkas RH, Qian J, Goldberg JL, Quigley HA and Zack DJ.
  TITLE     Gene expression profiling of purified rat retinal ganglion cells
  JOURNAL   Invest Ophthalmol Vis Sci 45 (8), 2503-2513 (2004)
   PUBMED   15277470
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CF977463.1, DV717487.1 and AA900118.1.
            
            On or before May 21, 2008 this sequence version replaced
            XP_001062455.1, XP_001062519.1, XP_001060165.1, XP_214983.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CF977464.1, FM113783.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..119
                     /organism="Rattus norvegicus"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q31"
     Protein         1..119
                     /product="RNA guanine-N7 methyltransferase activating
                     subunit"
                     /note="family with sequence similarity 103, member A1;
                     RNMT activating mRNA cap methyltransferase subunit"
                     /calculated_mol_wt=14283
     Region          11..87
                     /region_name="RAM"
                     /note="mRNA cap methylation, RNMT-activating mini protein;
                     pfam15320"
                     /db_xref="CDD:464643"
     CDS             1..119
                     /gene="Ramac"
                     /gene_synonym="Fam103a1; Rammet; RGD1310022"
                     /coded_by="NM_001127451.1:118..477"
                     /db_xref="GeneID:293058"
                     /db_xref="RGD:1310022"
ORIGIN      
        1 msdtseaipi feemfanrft qddkeyqeyl krppesppiv eewnsraggn qrnrgnwlqd
       61 nrqfrgrdnr rgwpsdnrsn qwhgrswgnn nypqqrpepy yqpncpqygh nqrppygyy
//
