LOCUS       NM_212547               2894 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ral guanine nucleotide dissociation stimulator
            like 2 (Ralgdsl2), mRNA.
ACCESSION   NM_212547 XM_215336 XM_342098 XM_347004
VERSION     NM_212547.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2894)
  AUTHORS   Scotland,R.L., Allen,L., Hennings,L.J., Post,G.R. and Post,S.R.
  TITLE     The ral exchange factor rgl2 promotes cardiomyocyte survival and
            inhibits cardiac fibrosis
  JOURNAL   PLoS One 8 (9), e73599 (2013)
   PUBMED   24069211
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2894)
  AUTHORS   Hurt,P., Walter,L., Sudbrak,R., Klages,S., Muller,I., Shiina,T.,
            Inoko,H., Lehrach,H., Gunther,E., Reinhardt,R. and Himmelbauer,H.
  TITLE     The genomic sequence and comparative analysis of the rat major
            histocompatibility complex
  JOURNAL   Genome Res 14 (4), 631-639 (2004)
   PUBMED   15060004
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DY316563.1 and BC107439.1.
            
            On Sep 12, 2009 this sequence version replaced NM_212547.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC107439.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-29                DY316563.1         1-29
            30-2894             BC107439.1         1-2865
FEATURES             Location/Qualifiers
     source          1..2894
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..2894
                     /gene="Ralgdsl2"
                     /gene_synonym="Ke1.5; Rab2l; Rgl2"
                     /note="ral guanine nucleotide dissociation stimulator like
                     2"
                     /db_xref="GeneID:294283"
                     /db_xref="RGD:1302985"
     exon            1..77
                     /gene="Ralgdsl2"
                     /gene_synonym="Ke1.5; Rab2l; Rgl2"
                     /inference="alignment:Splign:2.1.0"
     exon            78..275
                     /gene="Ralgdsl2"
                     /gene_synonym="Ke1.5; Rab2l; Rgl2"
                     /inference="alignment:Splign:2.1.0"
     CDS             120..2456
                     /gene="Ralgdsl2"
                     /gene_synonym="Ke1.5; Rab2l; Rgl2"
                     /codon_start=1
                     /product="ral guanine nucleotide dissociation
                     stimulator-like 2"
                     /protein_id="NP_997712.1"
                     /db_xref="GeneID:294283"
                     /db_xref="RGD:1302985"
                     /translation="MLPRPLRLLLDTNPPGGVVLSSFRSRDPEEGGDPGGRAVGGGQE
                     EEEEEEEEASVSIWDEEEDGATFTVTSRQYRPLDPSAPLPPPRSSRRLRAGTLEALVR
                     HLLDARTSGADMTFTPALLATHRAFTSTPALFGLVADRLEALESHPPGELERTTGVAI
                     SVLSTWLASHPEDFGSEVKGQLDRLESFLLRTGYAAREGVVGGSADLIRNLRARVDPR
                     APDLPKPLALPDDSPADPTDVLVFLADHLAEQLTLLDAELFLSLIPSQCLGGLWGHRD
                     RPGHSHLCPSVRATVTQFNKVAGAVVSSVLGATPTGEGPREVTVRPLRPPQRARLLEK
                     WIRVAEECRLLRNFSSVYAVVSALQSSPIHRLRAAWGETTRDSLRIFSSLCQIFSEED
                     NYSQSRELLMQEVKLQPPVEPHSKKAPRSGSRGGGVVPYLGTFLKDLVMLDAASKDEL
                     ENGYINFDKRRKEFAVLSELLRLQNECRGYDLRPNPDIQQWLQGLQPLTEAQSHRVSC
                     EVEPSGTIDSPAARTLRPALVITQWTEVLGSVGGPTPLVSWDRPTVGGDEVPGTPAPL
                     LTRLAQHMKWPSVSSLDSALESSPSLHSPADPGHLSPPASSPRPSRGHRRSASCGSPL
                     SGGTGEGASRSAGCGGGVSGPGSSDCRIIRVQMELGEDGSVYKSILVTSQDKAPSVIS
                     RVLKKNNRDSAVASEFELVQLLPGDRELTIPHSANVFYAMDGASHDFLLRQRRRPSAA
                     TSGSHSGPSASGTPPSEGGGGSFPRIKATGRKIARALF"
     exon            276..359
                     /gene="Ralgdsl2"
                     /gene_synonym="Ke1.5; Rab2l; Rgl2"
                     /inference="alignment:Splign:2.1.0"
     exon            360..538
                     /gene="Ralgdsl2"
                     /gene_synonym="Ke1.5; Rab2l; Rgl2"
                     /inference="alignment:Splign:2.1.0"
     exon            539..589
                     /gene="Ralgdsl2"
                     /gene_synonym="Ke1.5; Rab2l; Rgl2"
                     /inference="alignment:Splign:2.1.0"
     exon            590..887
                     /gene="Ralgdsl2"
                     /gene_synonym="Ke1.5; Rab2l; Rgl2"
                     /inference="alignment:Splign:2.1.0"
     exon            888..1139
                     /gene="Ralgdsl2"
                     /gene_synonym="Ke1.5; Rab2l; Rgl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1140..1243
                     /gene="Ralgdsl2"
                     /gene_synonym="Ke1.5; Rab2l; Rgl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1244..1328
                     /gene="Ralgdsl2"
                     /gene_synonym="Ke1.5; Rab2l; Rgl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1329..1397
                     /gene="Ralgdsl2"
                     /gene_synonym="Ke1.5; Rab2l; Rgl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1398..1472
                     /gene="Ralgdsl2"
                     /gene_synonym="Ke1.5; Rab2l; Rgl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1473..1505
                     /gene="Ralgdsl2"
                     /gene_synonym="Ke1.5; Rab2l; Rgl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1506..1627
                     /gene="Ralgdsl2"
                     /gene_synonym="Ke1.5; Rab2l; Rgl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1628..1723
                     /gene="Ralgdsl2"
                     /gene_synonym="Ke1.5; Rab2l; Rgl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1724..1835
                     /gene="Ralgdsl2"
                     /gene_synonym="Ke1.5; Rab2l; Rgl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1836..2129
                     /gene="Ralgdsl2"
                     /gene_synonym="Ke1.5; Rab2l; Rgl2"
                     /inference="alignment:Splign:2.1.0"
     exon            2130..2244
                     /gene="Ralgdsl2"
                     /gene_synonym="Ke1.5; Rab2l; Rgl2"
                     /inference="alignment:Splign:2.1.0"
     exon            2245..2869
                     /gene="Ralgdsl2"
                     /gene_synonym="Ke1.5; Rab2l; Rgl2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggactcggta gagggccaga gaccgacaag aacagaggcc cgggacccgc gcgcagcccc
       61 tcacccttcc cgagcaggca cccccaatgg cccgaccccg ctgattcctt ctctcggcca
      121 tgctcccgcg gcccctgcgg ctgcttttgg acacgaaccc ccccggggga gtcgtgttga
      181 gcagcttccg gagccgggac cccgaagagg gtggggaccc aggtggccgg gccgtgggcg
      241 gggggcagga ggaagaggag gaggaagaag aagaggcttc tgtgtcaatc tgggatgagg
      301 aggaggatgg tgcgaccttt actgtcacaa gccgccagta taggcctctt gatccctcgg
      361 cccccttgcc tccgcctcgc tcctcccgaa ggctccgtgc tggtactctg gaggccctgg
      421 tcagacacct cttggatgcc aggacatcag gggctgacat gacgttcact ccagccttgc
      481 tggccaccca ccgggccttc acctccactc ctgccctgtt tgggcttgtg gctgacaggc
      541 tggaagccct cgaatcgcat cctccgggcg agctagagag gaccacaggg gtagccatct
      601 ctgtactttc aacctggctg gcctctcacc ctgaggattt tggctctgag gtcaagggtc
      661 aacttgaccg gcttgagagc ttcttgcttc ggacagggta tgcagcacgg gagggtgttg
      721 tggggggcag tgctgacctc atccgaaacc tccgggcccg ggtggacccc cgggcccccg
      781 accttcctaa gcccctggcc cttcctgacg attcccctgc tgaccccacg gatgtcctgg
      841 tgttcctcgc tgaccacttg gccgaacagc tgaccctgct tgatgcggag ctgtttctca
      901 gtctgatccc ctctcagtgt ttgggaggcc tatggggtca cagagaccgg ccaggacatt
      961 ctcatctctg cccgtctgtc cgagctaccg tcacgcagtt caacaaggtg gcgggggcag
     1021 tagttagctc tgtcctgggg gccaccccaa ctggagaggg gccaagagag gtgactgtga
     1081 ggccactccg acccccacag agggcccggc tcctggagaa gtggatccgt gtggctgagg
     1141 aatgccgcct gcttaggaac ttctcctcag tgtatgctgt tgtgtccgct ctgcagtcca
     1201 gccctatcca taggcttcgg gcggcctggg gggagacaac cagggacagc ctcagaatct
     1261 tttccagcct gtgtcagatt ttctcagagg aggataatta ttcccagagc agagagctcc
     1321 tcatgcagga agtaaagctg cagccccctg tggagccaca ctccaagaag gccccaaggt
     1381 ctggctccag gggtgggggt gtggttccgt acctgggaac cttcctgaag gatctcgtga
     1441 tgctggatgc agcctccaag gatgagctgg agaatggcta catcaatttt gacaagcgga
     1501 ggaaggagtt tgctgtcctt tctgagctgc tgcgcctcca gaacgaatgt cgtggctatg
     1561 acctccgacc taaccctgat atccagcaat ggctccaggg cctccagcca ttaactgaag
     1621 ctcagagtca ccgtgtatcc tgtgaagtgg agccatctgg taccattgat tcccccgcgg
     1681 caaggacgct tcggccagca ctagtcatca cacagtggac ggaagttctg ggctccgttg
     1741 gaggccccac tccgcttgtg tcctgggatc ggcccactgt ggggggagat gaggtgccag
     1801 gaaccccggc ccctctgctg actcgcctcg cccagcacat gaagtggccg tctgtctcat
     1861 ctctggactc tgccctggaa agcagcccct ccctgcacag ccctgctgac cctggccacc
     1921 tctctcctcc agcctcctcc cctaggcctt ctcggggtca ccgacgctca gcctcctgcg
     1981 ggtctccgtt gagtgggggc acaggagagg gggcctctag gagtgctgga tgtgggggcg
     2041 gggtatctgg gccagggtcc tctgattgcc gaatcatccg agtccagatg gagcttgggg
     2101 aggatggcag cgtctacaag agcatcctgg tgacaagcca ggacaaggcc ccaagtgtta
     2161 ttagccgcgt ccttaagaaa aacaatcgtg attctgctgt ggcttcagag tttgagctgg
     2221 tgcagctgct acccggggat cgagagctga ccatcccaca ctcggctaac gtcttctatg
     2281 ccatggacgg cgcatctcac gacttcctcc tgcggcagcg gagaagacca tctgctgcca
     2341 cctcgggttc tcacagcggc ccctcggcct caggaactcc tccgagcgag ggaggagggg
     2401 gctcctttcc caggatcaag gccacaggga ggaagattgc acgggcactg ttctgaggat
     2461 gaagtcctgt tggtttacat agcaactcat accaggagtg agcagccaca cagggtggcc
     2521 cttctacccg agcagaaatc ccaaaaggcg gccagccacc ctggtacagt aaagtcacct
     2581 gtttacgaaa ccactgcgaa aaagccggcc ccgtgggact ggtgatcatg taaccaagtt
     2641 ggataactgc atatagcttc ctcctctggg gaacgtggca cgccatctgt gctggaaaga
     2701 gtattagcca ctgccacgtg acagcctgtg acgggccaag ggaaggccta gaggctgagc
     2761 ccagagcaga gggcagtgac aagaggttct gttgggggtt tcttgtcccg ctttgggggt
     2821 tcttgccact gtgataacac taagagaata aaccaaaaca ctacctgaaa aaaaaaaaaa
     2881 aaaaaaaaaa aaaa
//
