LOCUS       NM_001421313            9822 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus Ral GTPase activating protein catalytic subunit
            alpha 2 (Ralgapa2), mRNA.
ACCESSION   NM_001421313
VERSION     NM_001421313.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 9822)
  AUTHORS   Bohm,D., Keller,K., Pieter,J., Boehm,N., Wolters,D., Siggelkow,W.,
            Lebrecht,A., Schmidt,M., Kolbl,H., Pfeiffer,N. and Grus,F.H.
  TITLE     Comparison of tear protein levels in breast cancer patients and
            healthy controls using a de novo proteomic approach
  JOURNAL   Oncol Rep 28 (2), 429-438 (2012)
   PUBMED   22664934
REFERENCE   2  (bases 1 to 9822)
  AUTHORS   Chen,X.W., Leto,D., Xiong,T., Yu,G., Cheng,A., Decker,S. and
            Saltiel,A.R.
  TITLE     A Ral GAP complex links PI 3-kinase/Akt signaling to RalA
            activation in insulin action
  JOURNAL   Mol Biol Cell 22 (1), 141-152 (2011)
   PUBMED   21148297
REFERENCE   3  (bases 1 to 9822)
  AUTHORS   Shirakawa,R., Fukai,S., Kawato,M., Higashi,T., Kondo,H., Ikeda,T.,
            Nakayama,E., Okawa,K., Nureki,O., Kimura,T., Kita,T. and
            Horiuchi,H.
  TITLE     Tuberous sclerosis tumor suppressor complex-like complexes act as
            GTPase-activating proteins for Ral GTPases
  JOURNAL   J Biol Chem 284 (32), 21580-21588 (2009)
   PUBMED   19520869
REFERENCE   4  (bases 1 to 9822)
  AUTHORS   Gridley,S., Chavez,J.A., Lane,W.S. and Lienhard,G.E.
  TITLE     Adipocytes contain a novel complex similar to the tuberous
            sclerosis complex
  JOURNAL   Cell Signal 18 (10), 1626-1632 (2006)
   PUBMED   16490346
REFERENCE   5  (bases 1 to 9822)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-263               JAXUCZ010000003.1  154391785-154392047 c
            264-374             JAXUCZ010000003.1  154358621-154358731 c
            375-427             JAXUCZ010000003.1  154352297-154352349 c
            428-485             JAXUCZ010000003.1  154332668-154332725 c
            486-529             JAXUCZ010000003.1  154325812-154325855 c
            530-707             JAXUCZ010000003.1  154324479-154324656 c
            708-823             JAXUCZ010000003.1  154323240-154323355 c
            824-962             JAXUCZ010000003.1  154321911-154322049 c
            963-1162            JAXUCZ010000003.1  154319991-154320190 c
            1163-1390           JAXUCZ010000003.1  154316714-154316941 c
            1391-1558           JAXUCZ010000003.1  154309861-154310028 c
            1559-1696           JAXUCZ010000003.1  154308354-154308491 c
            1697-1845           JAXUCZ010000003.1  154305552-154305700 c
            1846-1957           JAXUCZ010000003.1  154302570-154302681 c
            1958-2195           JAXUCZ010000003.1  154298583-154298820 c
            2196-2360           JAXUCZ010000003.1  154295586-154295750 c
            2361-2495           JAXUCZ010000003.1  154286544-154286678 c
            2496-2609           JAXUCZ010000003.1  154285903-154286016 c
            2610-2707           JAXUCZ010000003.1  154283893-154283990 c
            2708-2798           JAXUCZ010000003.1  154280197-154280287 c
            2799-2975           JAXUCZ010000003.1  154278694-154278870 c
            2976-3169           JAXUCZ010000003.1  154263710-154263903 c
            3170-3268           JAXUCZ010000003.1  154262838-154262936 c
            3269-3424           JAXUCZ010000003.1  154262460-154262615 c
            3425-3553           JAXUCZ010000003.1  154235151-154235279 c
            3554-3682           JAXUCZ010000003.1  154231739-154231867 c
            3683-3741           JAXUCZ010000003.1  154230860-154230918 c
            3742-3850           JAXUCZ010000003.1  154227028-154227136 c
            3851-3961           JAXUCZ010000003.1  154221980-154222090 c
            3962-4030           JAXUCZ010000003.1  154220599-154220667 c
            4031-4168           JAXUCZ010000003.1  154220209-154220346 c
            4169-4352           JAXUCZ010000003.1  154218973-154219156 c
            4353-5124           JAXUCZ010000003.1  154209204-154209975 c
            5125-5196           JAXUCZ010000003.1  154207653-154207724 c
            5197-5320           JAXUCZ010000003.1  154201397-154201520 c
            5321-5476           JAXUCZ010000003.1  154200014-154200169 c
            5477-5635           JAXUCZ010000003.1  154193941-154194099 c
            5636-5763           JAXUCZ010000003.1  154182163-154182290 c
            5764-5885           JAXUCZ010000003.1  154132512-154132633 c
            5886-5925           JAXUCZ010000003.1  154119121-154119160 c
            5926-9822           JAXUCZ010000003.1  154112005-154115901 c
FEATURES             Location/Qualifiers
     source          1..9822
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q41"
     gene            1..9822
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /note="Ral GTPase activating protein catalytic subunit
                     alpha 2"
                     /db_xref="GeneID:296211"
                     /db_xref="RGD:1308023"
     exon            1..263
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     CDS             158..5890
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /note="Ral GTPase-activating protein alpha subunit 2; Ral
                     GTPase activating protein catalytic alpha subunit 2; Ral
                     GTPase activating protein, alpha subunit 2 (catalytic);
                     250 kDa substrate of Akt"
                     /codon_start=1
                     /product="ral GTPase-activating protein subunit alpha-2"
                     /protein_id="NP_001408242.1"
                     /db_xref="GeneID:296211"
                     /db_xref="RGD:1308023"
                     /translation="MFSRRSHGDVKKSTQKVLDPKKDVLTRLKHLRALLDNVDASDLK
                     QFFETNYSQIYFIFYENFITLENSLKLKGNNKSQREELDSILFLFEKILQFLPERIFF
                     RWHYQSIGSTLKKLLHTGNSIKIRCEGIRLFLLWLQALQTNCAEEQVLIFACLVPGFP
                     AVLSSRGPCTLETLINPSPSVVDAKIYPEEITPLLPAVSGEKIAEDQTCFFLQILLKY
                     MVIQAASLEWKNKENQDTGFKFLFTLFRKYYLPHLFPSFTKLTNIYKPVLEIPHLRPK
                     PLYVTVTRDNETIYSTKIPYMAARVVFIKWIVTFFLEKKYLTATQNTKNGVDVLPKII
                     QTVGGGAIQEKVPELDGAGATEQDKSHSNSSTLSDRRLSNSSLCSIEEEHRTVYEMVQ
                     RILLSTRGYVNFVNEVFRQAFLLPSCEISITRKVVQVYRKWILQNKPVFMEEPDKKDV
                     AEEDADKLGLSETDSKEVSSESSGHKRSSSWGRTYSFTSAMSRGCVTEEDNTNVKAGA
                     QAMLQVFLTNAANVFLLEPCVEVPMLLREQVDACKAVLIIFRRMIMELTMNQKTWEQM
                     LQILLRITEAVMQKPKDKLVQDSFARSLAGLLFRTLIVAWIRANLCVYISRELWDDFL
                     RVLSSLTEWEELITEWSNIMDSLTAVLARTVYGVEMTNLPLDKLSEQKEKKQRGKGCV
                     LEPQKGTAVGRSFSLSWRSHPDVTEPMRFRSATTSGAPGVEKARNTVRQKATEVEEFQ
                     QAESTAAADCDYLVVGQQPVPRSSSTSDITERLYSDSSQGYSPMLPHPAFYMASGDLN
                     SGPHACTTGPLPLSHLPSPGQKVENSQNLSSSEPKSVQESKGHVTHEHEGVTILVRRS
                     SSPAELDLKEESQQTHGRCRERQKSESTGSDMAVGYSNEAELPVSPWQTCEEDPELST
                     PTDAVADSDARHWLQLSPTDASNLTESRECLADDCSIIAGGNLTGWHPDSAAVLWRRV
                     LGILGDVNNIQSPKIHAKVFSYLYELWYKLAKIRDNLAISLDNQSSPSPPLLIPPLRM
                     FASWLFKATTLPNEYKEGKLQAYKLICAMMTRRQDVLPNSDFLVHFYLVMHLGLTSED
                     QDVLNTIIKNCSPRFFSLGLPGFSMLVGDFITAAARVLSTDMLAAPRSEALTLLGSLV
                     CFPNTYQEIPLLQSVPEVSDVVTGAEDVKHYLINILLKNATEEPNECARCIAICSLGV
                     WICEELAQCASHPQVKDAINVIGVTLKFPNKIVAQVACDVLQLLVSYWEKLQMFETAL
                     PRKMAEILVATIAFLLPSAEYSSVETDKKFIVSLLLCLLDWCMALPVSALLHPVSTAV
                     IEELHPSRAPLLDYIYRVLHCCVCGSSTYTQQSHYTLTLADLSSTDYDPFLPLANVRN
                     SEPVQYHSSADLGNLLTVEEEKKRRSVELIPLTARMVMAHLVNHLGHYPLSGGPAVLH
                     SLVSENHDNAHVEGTELSSEVFRSPNLQLFVFNDSTLISYLQTPAEGPAGGTSGGSLS
                     DVRVIVRDISGKYSWDGKVLYGPLEGRLAPSGRNPSFQISGWHHHTCGPQSNLFHGEE
                     GDDVLDKLLENIGHTSPECLLPSQLNLNEPSPTPSAMNCDQEKEIIEVILRQSTQEDE
                     YVQRCHSNSAVKVTSQGQPSPVEPRGPFYFCRLLLDDLGMNSWDRRKNFHLLKKNSKL
                     LRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILANERGSQAYEDFVAGLGWEVDLST
                     HCGFMGGLQRNGSTGQTAPYYATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHI
                     VWSEHSRDYRRGIIPTAFGDVSIIIYPMKNHMFFITITKKPEVPFFGPLFDGAIVSGK
                     LLPSLICATCINASRAVKCLIPLYQSFYEERALYLEAIIQNHREVMTFEDFAAQVFSP
                     SPSYSLSGTD"
     exon            264..374
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            375..427
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            428..485
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            486..529
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            530..707
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            708..823
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            824..962
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            963..1162
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            1163..1390
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            1391..1558
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            1559..1696
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            1697..1845
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            1846..1957
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            1958..2195
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            2196..2360
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            2361..2495
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            2496..2609
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            2610..2707
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            2708..2798
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            2799..2975
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            2976..3169
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            3170..3268
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            3269..3424
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            3425..3553
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            3554..3682
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            3683..3741
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            3742..3850
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            3851..3961
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            3962..4030
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            4031..4168
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            4169..4352
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            4353..5124
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            5125..5196
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            5197..5320
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            5321..5476
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            5477..5635
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            5636..5763
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            5764..5885
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            5886..5925
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
     exon            5926..9822
                     /gene="Ralgapa2"
                     /gene_synonym="AS250; p220; RGD1308023"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttcctggag ccaccgctta agctgaggcg gcgcggcagc taggaggggg gcggctagtg
       61 gccggagcga cacgcgcccg tcgcgaccct atgcagtgac ttgtgcggcg caggcgcctc
      121 ctgccccgcc ggcggggccc aggcttaccg cggcgggatg ttctcccgaa ggagccacgg
      181 agatgtgaaa aagtccacgc agaaggtgct ggaccccaag aaggacgtgc tgacccgcct
      241 gaagcacctg cgggcgctgc tggataacgt ggatgcaagc gatcttaagc agttttttga
      301 gaccaactat tctcagatat atttcatctt ctatgaaaat tttataacac tggaaaatag
      361 tttgaagtta aaagggaata ataagtcgca aagggaggag ctggactcca tcctctttct
      421 ttttgaaaaa atacttcagt ttctacctga acgaattttc tttcgatggc attaccagag
      481 tataggctca actttaaaga agcttttaca cactggaaat tctattaaga taaggtgtga
      541 aggaatcaga ctgtttcttt tgtggcttca agcacttcag acaaactgtg cagaagagca
      601 ggtgctgatt ttcgcttgcc tcgtgcctgg tttcccagcg gtcttgtcat ccaggggtcc
      661 ctgcacgctg gagacactca tcaaccctag ccctagtgta gttgatgcaa aaatataccc
      721 agaggaaatc accccacttc tgccggctgt atcaggggag aagatcgctg aggaccaaac
      781 ctgctttttt cttcaaatac tgttgaaata catggttatt caggctgcaa gtttggagtg
      841 gaagaataag gagaatcaag atactggttt taaatttctt tttacattgt tccgaaagta
      901 ttatcttcct catttgtttc catcatttac taagttaacc aacatctaca aacctgtact
      961 tgaaatcccc catttgagac caaagccact atatgttact gtaactcgag ataatgaaac
     1021 aatttacagt acaaaaattc catacatggc agctcgcgtt gtcttcatta aatggattgt
     1081 aaccttcttt ttggaaaaga agtatctgac cgcaacacag aacactaaaa atggagttga
     1141 cgtattgcct aaaatcatcc agactgttgg tggtggtgca atacaagaaa aggtgccaga
     1201 gctggatggt gccggggcca cagagcagga caaaagccat tctaacagta gcaccttgtc
     1261 cgaccgaaga ctcagcaact ccagtctctg tagcattgaa gaggagcatc ggacagtgta
     1321 tgaaatggtg cagcggatcc tcctgtctac acgcggttac gtgaattttg tgaatgaagt
     1381 atttcgacag gcatttttgt tgccttcctg tgagatatct ataacaagaa aagtagttca
     1441 ggtgtacagg aaatggatcc tgcagaacaa gcctgtgttc atggaagaac cagataaaaa
     1501 ggacgttgct gaagaagatg ctgacaaatt aggactttca gagactgact ccaaggaggt
     1561 ctcatccgaa agttctggtc ataaacggtc atccagttgg ggacgcacgt attccttcac
     1621 aagtgccatg agcagagggt gtgtgacaga ggaggacaac acaaatgtga aagctggggc
     1681 ccaagctatg ttgcaggttt ttcttacaaa tgctgcaaat gtctttttgc tggaaccatg
     1741 tgttgaagtt cccatgctcc tgagagaaca agtagatgcc tgtaaagctg tcctgattat
     1801 ttttcggcga atgataatgg aactcacaat gaatcagaag acatgggagc agatgttgca
     1861 aatccttctc aggataacag aagccgtcat gcagaagcca aaggataagc ttgtacagga
     1921 ttcatttgcc cggagcttgg cagggctgct cttcaggaca cttatcgtgg cttggatccg
     1981 agcaaacctg tgtgtgtaca tttctcggga gctctgggat gactttctca gggtgctgtc
     2041 atcccttaca gaatgggagg aactcatcac tgagtggtct aatatcatgg actccttgac
     2101 agccgtgctt gcgagaactg tgtatggagt tgaaatgaca aacctacctc tggataagtt
     2161 aagtgaacag aaggagaaga agcagcgagg caaaggttgt gtcctagagc cccaaaaagg
     2221 gactgctgtt gggagatcct tttctcttag ctggcgcagc catccagatg taacggagcc
     2281 aatgagattc aggagtgcca ccacatctgg agccccagga gtagagaagg caagaaatac
     2341 tgtccgtcaa aaagcgactg aagtggagga gttccaacag gcagagagca cggctgcagc
     2401 cgactgtgac tatcttgtgg taggacagca gccggtcccc cggagcagca gcacctctga
     2461 catcactgag cgcttgtact cagattcttc tcaaggttac agtcccatgc tgcctcatcc
     2521 agctttttac atggcttctg gggatctaaa ctcaggtcct catgcctgca caacaggtcc
     2581 tttaccactg agccatctcc ccagcccagg tcaaaaggta gaaaattcac agaatttgag
     2641 ctcttcagaa cccaagtctg ttcaagagag taaaggtcac gtgacgcatg aacacgaagg
     2701 agtaacaatc ttggttcgaa ggagcagcag ccctgctgag ctggatctga aggaggagtc
     2761 acagcagaca cacggacgat gcagggagag acagaagagt gaaagtactg gtagtgacat
     2821 ggctgtgggc tacagtaacg aggcagagct acctgtgagc ccttggcaga cctgtgagga
     2881 ggacccggaa ctgagcactc ccacagatgc tgtggctgac tctgatgccc gccattggtt
     2941 acaactgagt cctactgatg cttccaactt aacagagagc agggaatgcc tggcagacga
     3001 ctgcagcata attgctggag ggaacctcac tggttggcac ccggactctg ctgctgtgct
     3061 gtggcgaaga gtcttgggaa tccttggaga tgtgaataac atccagtcac cgaagatcca
     3121 tgccaaggtt ttcagctatc tctatgaact gtggtacaag ctggccaaga tacgagataa
     3181 tctcgcaata agcctggata accagtcgtc tccatctcct ccactcttga tcccaccact
     3241 cagaatgttt gcatcatggc tatttaaggc tacaactctg ccgaatgaat ataaagaagg
     3301 caaactgcaa gcctacaaac tgatctgtgc catgatgacc aggcgccagg atgttctgcc
     3361 caactctgat ttcctggtgc atttttacct cgtgatgcac ctgggattaa ccagcgagga
     3421 ccaggatgtc ttaaacacca tcataaaaaa ctgctcgccc cgctttttct ccctgggttt
     3481 gcctggcttc tccatgttgg tgggggactt tatcactgct gctgccaggg tcctcagtac
     3541 agacatgttg gcggcacccc gttcagaagc tctcactctc ctcggttccc ttgtctgctt
     3601 cccaaatacc taccaggaga tccctctgct gcagtcagta ccagaagtga gtgatgttgt
     3661 cacgggcgct gaagacgtca agcattacct cataaatatt ttactgaaga atgctaccga
     3721 ggaaccaaat gaatgtgcaa gatgcatcgc catttgctcc ctcggggtct ggatctgtga
     3781 agagcttgca cagtgtgcca gccatcctca ggtgaaggat gccatcaatg tgataggtgt
     3841 aactttgaag tttcctaaca agatcgtggc tcaggtagcc tgtgatgttc ttcagttgct
     3901 ggtttcctac tgggaaaagc ttcagatgtt tgaaactgct ctcccacgaa aaatggcaga
     3961 aatccttgtg gccacaattg ctttcctttt accaagtgca gagtactctt cagtggaaac
     4021 agataaaaag tttattgtgt ccttgctcct ttgtctcttg gactggtgca tggcactgcc
     4081 tgtgagtgcc ctcctccacc ctgtgtctac ggcagtcata gaggaattgc acccatcccg
     4141 ggctcccttg ctggattata tctacagggt tctgcactgc tgtgtctgtg gctcaagcac
     4201 atacacccag caaagtcact atactttgac cttggctgac ctgtcatcca cggattatga
     4261 ccccttccta cctctggcaa acgtgaggaa ctccgagcct gtccagtacc attcatcagc
     4321 agacctgggg aacctgctga ctgtggaaga ggagaagaag agaagaagtg tggaactgat
     4381 ccccctcact gcacgcatgg tgatggccca cctagtgaac caccttggcc attatccact
     4441 gagtgggggt cctgccgtgc tgcacagcct ggttagtgag aaccatgaca atgcccatgt
     4501 ggaaggaact gagctgtcct cagaggtgtt caggagccca aacctgcagc tcttcgtctt
     4561 taatgatagc accctcatct cctaccttca aacaccagca gaaggaccag ctggaggaac
     4621 ttcagggggt tccctctcag acgtgagagt cattgtgagg gatatctcag ggaagtactc
     4681 ttgggatggc aaggttttat atggacctct ggaaggccgc ctggctccca gtggaaggaa
     4741 tccctcattt cagatttctg gctggcacca tcacacatgt ggaccacaga gcaatttgtt
     4801 tcacggtgag gagggagatg atgtgcttga caaattactt gaaaacattg gccatacaag
     4861 ccctgaatgc cttttaccat cacaactaaa tctaaatgag ccttccccaa ccccgagtgc
     4921 aatgaactgt gaccaagaaa aggaaatcat cgaggtcatc ctgcgccaga gcacacagga
     4981 ggatgagtat gtgcagaggt gtcactctaa ttctgcagta aaggtcacga gccaagggca
     5041 gccctcgcca gtggagcccc ggggaccctt ctatttctgc aggctgttgc ttgatgactt
     5101 gggaatgaat tcctgggaca gaagaaagaa ttttcatttg ttgaagaaaa attcaaaatt
     5161 attgagagag ctaaagaatc tggactctcg tcagtgccgc gagacccata agattgcagt
     5221 gttctacatt gctgaaggac aagaagacaa gtgttccatt ctagccaatg aaagaggaag
     5281 ccaagcctat gaagactttg ttgctggtct tggatgggag gtggatctct caacccactg
     5341 tgggtttatg ggtggtcttc agcgcaatgg cagcacggga cagacggccc cttactatgc
     5401 tacctcgacc gtggaagtaa ttttccacgt ttccactcga atgccatcag attcagatga
     5461 ctcactcacc aaaaagctcc gtcacctggg gaatgacgag gtccacatcg tctggtctga
     5521 acactccagg gactaccgca ggggcattat tccaacagcc tttggagatg tttccatcat
     5581 tatttaccca atgaagaatc atatgttctt catcacaata accaagaagc ctgaggttcc
     5641 attctttggg cctctgttcg atggagcaat cgtgagtggg aagctgctgc caagccttat
     5701 ctgtgccacg tgcatcaatg ccagcagagc ggtgaagtgc ctcatcccac tctatcagag
     5761 cttctacgaa gagcgagcgc tgtatctgga agcaataatt caaaaccacc gggaagtcat
     5821 gacatttgag gatttcgctg cccaagtctt ttctccctct cccagctact ctctcagtgg
     5881 aacggattaa aatacataat ggtctcattg cgatacttga gcaaggggtc ttgacctcca
     5941 acctgagtgt ggaccccaag aaaagcctcc atgtggaaga gacaggcaag actcccctga
     6001 tttcctcaga acctcagaat ccagacttca ggaatctgcc actgtacccg cacgtgcagc
     6061 aggctttctc atggctgggc cccagcgtct tccgacggat ctgtggaacc ttcaaacaat
     6121 gcagcatccc tcttgtcctg gaatctcacc aaaccctggg catcagaaga agaaaagaaa
     6181 gaagtcaccc tcaaccaaga acaaacctgc tgtcatacgg gcaatgggga agccaggagt
     6241 ctttaggcag aacacagtag caaaaggttc ggggcccaca gggaaggggc aaagggcact
     6301 acttgtctgt atcaccgaat cgttttcctt tcctttacac acccaagcgt gattcccaaa
     6361 agggctgaca aagcaactgt gtaatggttg gaggaatttc ctccatactg attttgctaa
     6421 tccttaatgt taggttttat attttactca aaattttacc atcatggaaa ctggctgtcc
     6481 ccagggtcgt ttcctacagg aagtttcatc tccaccattg aaccctttcc acctggaact
     6541 ttccactgac ttaaaattct cctgacaaca cagagttctg tcaggtgatg gtcccacaca
     6601 gagcaagagg agtgtctaaa aatacgggag tatccccgtg agaacactag gcagatgggt
     6661 agcatccctg ctcagcccaa ctcagcccag cccagcccag caccactcac atcaacacag
     6721 attagtggct gctccagctc cagggctgac cagcacccac attgtgtccc ctgaaagctc
     6781 accagcagtc ctcctcctgt ctgctgttca gagtccaaga caggccttag aaacagcact
     6841 tgtcacagga gttttagggt aacagattcc aggcaataga tttgacccat acctatatac
     6901 acatacacat atatggatca aatttcatat attggttcca aggagggtgt gttgtgccta
     6961 ttaggtatgg gagggaagga aggagttaaa tgtgtccctt actagacatg ggcatcttgg
     7021 accttagaac ctggcaacta agagttcaca gggaagactt ctgcgtggtc acgcccccac
     7081 tgccatgccc ccccacacac acacacacac accccagccc cgtgcctctg tcctggctct
     7141 agtgctgtcc cagagctcca gtgttgcctc atcctttcct ctgcctcaga gcaaaacaga
     7201 aaatgcagca gaagccaccc cttgcatggg gaagaatgtc ctggatgtgg ccacctctct
     7261 tactttcctc tgccctcaga tctcacacat gttactgctc ctagcctgct tggtcactcc
     7321 tctgcttatc cacctcatca gtgtccagtc cccagagaag ccagcttttt ataactacta
     7381 cagagctggg tcagctgcta ctgatcttgg tagaaaaagg agcagagcca gaagccatac
     7441 tcagtcttgt agtgagtggg aattctgaga aaggctttct aggagcacca tcccactgca
     7501 gggagaatcc agcctgctgc tttgaaggga gttcaacagc ctctcatccc agacccacag
     7561 acaggagccc ctggagagct gcttgaagat catagagaga gcaggacatt gcaaagtaga
     7621 agaaaggctc tattccctgt gtgctgtttc ctaaaggtcc agaatactca cttagtggga
     7681 gcttaatggt gatagaaggg aaatcgcctg tcatgacgtt ttccattgtg tcagtgaaac
     7741 cttgattctt ataccaccca ctgtgtgtgt gtgtgtgtgt atctgggtat atatctgtgt
     7801 gtgtctgtat gtctctgtat gtgtgtgtgt gtctgtgtgt gtgtctcttt gtatgtgtgt
     7861 ctgtgtgtgt gtgtccatgt ctctgtgtgt ggctgtctct gtgtatgtgt ctgtgtgtcc
     7921 gtgtctgtgt gtgtgtgtgt ccatgtctct gtgtgtgcgt gtatctgtgt gtgtgtctgt
     7981 gtgtgtgtgt ccatgtctct gtgtgtgcgt gtatctgtgt gtgtgtctgt gtccgtgtgt
     8041 gtgtgtgtct gtccatgtct ctgtgtgtgc gtgtatgtgt gtgtgtgtgt gtctccgtgt
     8101 gtgtgtgtgt ctgtgtgtgt gtggcctgtg tgctcagact tctgttattg atctcctact
     8161 ttggtgttta caaagcaccc agacctggct cctgcagaaa gcacctccca agtcctgggc
     8221 accaaaggcc cctgcagtac tcggtcattg agtagcttct gtgggaacac ttaccttcag
     8281 gccccatgaa cactgttgtg gaattcttgt cattttggaa gtctttcact tttgtctttt
     8341 tcagtcataa cagaacccag ggccacaacc caggtcccag aggtcctgtc tcactcccac
     8401 agctgtctct tcataatgtc atttgcttcc acaagccctc agactcggag tgagaaattc
     8461 aattggaggt agcaaataat ttgaacttct tgtaccctaa tgattttatc aaccccatgc
     8521 ccaggttgac agcaacagtt catgtctgtt tctgttttac ttatctgttt agtccatggg
     8581 tcttgggttg gttggtaata gctctggtta gagacctaag agctgggagt agggactctg
     8641 gcaaccatgc ttgattagac ttagcagctc ttgttatttg gggtggaaaa ttgaaatgat
     8701 caagtttggt gtttcctttt gtcagttaga aaagcaaaca ttgtgttttc ataataaatg
     8761 tcttttaaca aaattactaa gggtcactca tctggtgaga ccctcctgag agacactcgt
     8821 cacgctagta ttagtaggtc agccatctgt gataaaagtg tccctaatta ccccaaagtg
     8881 tggtaagatt ctttgggctc atgcagggtc tggccagtac ccttctccac atgctgattt
     8941 ctggatgtcc atgaagaagg aaactgatgt ttatagtctt attgtataga ctttcatgct
     9001 gtaaaaaaaa aattagtaac cccacaaaat taggactttt taaaaatagc cagacctgca
     9061 gcagactgaa gaaaggaagt gcagcctggt gagtgactct tacagtgtct tcagcagcca
     9121 agcaggcatt tcctgagagc cccgggatgg actctgactc tgcagtgtgg ctgtttagta
     9181 ggacccttag ccttacacag ctccagagag ccatgcaaac cctgtcttcc tgaccgtcct
     9241 caggtgtccc ttcctttcct ccactgacct gtggtggagg tttgatgagc cctctaaacc
     9301 ttcctctgtg tcttatatgt agctgtatca ctccatactt actgaagggg atgtcgcatc
     9361 taagggaaac tcatcaagag atgcccagat gctatgtatg tgatgtacac agtaagcaag
     9421 catttcctta gtgtcaggtc tacagtatgt agtatgtgta aatagggggc aatttgatag
     9481 agatgttgaa ttaagttata tagcatgtca tttgattgtt ttgcggtctc ttgttacttc
     9541 ccaatgctgc acatctaggt tgttctgagg ggtgtgtgat ctgctccccc ttgtcaggag
     9601 tgtacatgta caccagggac atggtacact ccacaaaggc agccctgctt ggaaaactct
     9661 tagctccata atggtgccac tcaactccag ctcactcttt ttcgttctga tttactgtga
     9721 tgattcgatg aatgagaaac acagcaccct aggtgctacg tgtttctgac attctcatag
     9781 tctgtaggaa aataaaagtt tatcccacca tctaataaaa aa
//
