LOCUS       NP_001386138             978 aa            linear   ROD 29-MAR-2024
DEFINITION  ankycorbin isoform 1 [Rattus norvegicus].
ACCESSION   NP_001386138 XP_006232123
VERSION     NP_001386138.1
DBSOURCE    REFSEQ: accession NM_001399209.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 978)
  AUTHORS   Qian,X., Mruk,D.D. and Cheng,C.Y.
  TITLE     Rai14 (retinoic acid induced protein 14) is involved in regulating
            f-actin dynamics at the ectoplasmic specialization in the rat
            testis*
  JOURNAL   PLoS One 8 (4), e60656 (2013)
   PUBMED   23565266
  REMARK    GeneRIF: Rai14 is involved in the re-organization of actin
            filaments in Sertoli cells during the epithelial cycle,
            participating in conferring spermatid polarity and cell adhesion in
            the testis.
REFERENCE   2  (residues 1 to 978)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Jan 4, 2022 this sequence version replaced XP_006232123.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643288.8758.1,
                                           SRR26643294.8158.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..978
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q16"
     Protein         1..978
                     /product="ankycorbin isoform 1"
                     /note="ankycorbin; retinoic acid-induced protein 14;
                     ankyrin repeat and coiled-coil structure-containing
                     protein"
                     /calculated_mol_wt=109003
     Region          1..248
                     /region_name="ANKYR"
                     /note="Ankyrin repeat [Signal transduction mechanisms];
                     COG0666"
                     /db_xref="CDD:440430"
     Site            1
                     /site_type="acetylation"
                     /note="N-acetylmethionine.
                     /evidence=ECO:0000250|UniProtKB:Q9P0K7; propagated from
                     UniProtKB/Swiss-Prot (Q5U312.2)"
     Site            11
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9P0K7; propagated from
                     UniProtKB/Swiss-Prot (Q5U312.2)"
     Region          18..51
                     /region_name="ANK 1"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5U312.2)"
     Region          23..50
                     /region_name="ANK repeat"
                     /note="ANK repeat [structural motif]"
                     /db_xref="CDD:293786"
     Site            order(52,54,58..59,62..64,66..67,71,74,83,85,87,91..92,
                     95..97,99..100,104,107,116,118,120,124..125,128..130,
                     132..133,137,140,149)
                     /site_type="other"
                     /note="oligomer interface [polypeptide binding]"
                     /db_xref="CDD:293786"
     Region          52..83
                     /region_name="ANK repeat"
                     /note="ANK repeat [structural motif]"
                     /db_xref="CDD:293786"
     Region          52..81
                     /region_name="ANK 2"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5U312.2)"
     Region          85..116
                     /region_name="ANK repeat"
                     /note="ANK repeat [structural motif]"
                     /db_xref="CDD:293786"
     Region          85..114
                     /region_name="ANK 3"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5U312.2)"
     Region          118..149
                     /region_name="ANK repeat"
                     /note="ANK repeat [structural motif]"
                     /db_xref="CDD:293786"
     Region          118..147
                     /region_name="ANK 4"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5U312.2)"
     Region          151..182
                     /region_name="ANK repeat"
                     /note="ANK repeat [structural motif]"
                     /db_xref="CDD:293786"
     Region          151..180
                     /region_name="ANK 5"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5U312.2)"
     Region          184..215
                     /region_name="ANK repeat"
                     /note="ANK repeat [structural motif]"
                     /db_xref="CDD:293786"
     Region          184..213
                     /region_name="ANK 6"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5U312.2)"
     Region          217..247
                     /region_name="ANK 7"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5U312.2)"
     Region          248..299
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5U312.2)"
     Site            249
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q5U312.2)"
     Region          270..276
                     /region_name="Nuclear localization signal.
                     /evidence=ECO:0000250"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5U312.2)"
     Site            281
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q5U312.2)"
     Site            286
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9P0K7; propagated from
                     UniProtKB/Swiss-Prot (Q5U312.2)"
     Site            293
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9P0K7; propagated from
                     UniProtKB/Swiss-Prot (Q5U312.2)"
     Site            295
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0000250|UniProtKB:Q9P0K7; propagated from
                     UniProtKB/Swiss-Prot (Q5U312.2)"
     Site            297
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0000250|UniProtKB:Q9P0K7; propagated from
                     UniProtKB/Swiss-Prot (Q5U312.2)"
     Site            300
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9P0K7; propagated from
                     UniProtKB/Swiss-Prot (Q5U312.2)"
     Site            304
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9EP71; propagated from
                     UniProtKB/Swiss-Prot (Q5U312.2)"
     Site            318
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q5U312.2)"
     Site            327
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9P0K7; propagated from
                     UniProtKB/Swiss-Prot (Q5U312.2)"
     Site            329
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9P0K7; propagated from
                     UniProtKB/Swiss-Prot (Q5U312.2)"
     Site            340
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9P0K7; propagated from
                     UniProtKB/Swiss-Prot (Q5U312.2)"
     Site            341
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9P0K7; propagated from
                     UniProtKB/Swiss-Prot (Q5U312.2)"
     Site            358
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9P0K7; propagated from
                     UniProtKB/Swiss-Prot (Q5U312.2)"
     Region          388..424
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5U312.2)"
     Region          <430..>723
                     /region_name="MukB"
                     /note="Chromosome condensin MukBEF, ATPase and DNA-binding
                     subunit MukB [Cell cycle control, cell division,
                     chromosome partitioning]; COG3096"
                     /db_xref="CDD:442330"
     Site            511
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9P0K7; propagated from
                     UniProtKB/Swiss-Prot (Q5U312.2)"
     Site            514
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9P0K7; propagated from
                     UniProtKB/Swiss-Prot (Q5U312.2)"
     Region          636..>896
                     /region_name="SMC_N"
                     /note="RecF/RecN/SMC N terminal domain; cl47134"
                     /db_xref="CDD:481474"
     Site            666
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9P0K7; propagated from
                     UniProtKB/Swiss-Prot (Q5U312.2)"
     CDS             1..978
                     /gene="Rai14"
                     /coded_by="NM_001399209.1:115..3051"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="GeneID:294804"
                     /db_xref="RGD:1305942"
ORIGIN      
        1 mkslkakfrk sdtnewnknd drllqaveng daekvasllg kkgasatkhd segktafhla
       61 aakghveclk vmvthgvdvt aqdssghsal hiaaknghpe yikkllqyks paesvdnlgk
      121 talhyaaaqg slqavqvlce hkspinlkdl dgnipllvai qnghseachf lldhgadvns
      181 rdkngrtalm lacetgsant vealikkgad lnlvdslghn alyysklsen agiqslllsk
      241 isqdadlktp tkakqhdqvs kissersgtp kkrkappppi sptqlsdvss prsitstpls
      301 gkesvffaea pfkaeissiq enkdrlsdst agadslldvs seadqqdllv llqakvaslt
      361 lhnkelqdkl qakspketea dlsfqsfhst qtdlapspsk ssdipssdak ssppvehpag
      421 tstadrdvii qqlqdtlhdl qkrletseae kkqlqdelqs qrtdttclnn teisengsdl
      481 sqklkdtqsk yeeamkevls vqkqmklgll shesadgdsr lrevrvtded vdalkqdlqr
      541 aleeskrdka rvqeletklv ekekaeatkp ssevceemrn sycsvienmn kekaflfeky
      601 qqaqeeimkl kdtlksqmpq eapddsgdmk etmnrmvdel nkqvselsql yreaqaeled
      661 yrkrksleda teyihraehe rlmhlsnlsr tkaeeslsdm rsqyskvlne ltqlkqlvda
      721 hkensvsite hlevittlrt makemeektv tlqehlaske gevaklekql aeekaamsda
      781 mvpkasyekl qaslesevna laaklkesvk ekekahseva qvrsevsqak rekeniqtll
      841 kskeqevtel vqkfqraqee laglkrcset sskleedkde kinemtkevl klkealnsls
      901 qlsystsssk rqtqqlemlq qqvkqlqnql aeckkqhqev vsvyrmhlly avqgqmdedv
      961 qkvlkqiltm cknqsqkk
//
