LOCUS       NM_001037218            3687 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus Rap associating with DIL domain (Radil), mRNA.
ACCESSION   NM_001037218 XM_221937
VERSION     NM_001037218.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3687)
  AUTHORS   de Kreuk,B.J., Gingras,A.R., Knight,J.D., Liu,J.J., Gingras,A.C.
            and Ginsberg,M.H.
  TITLE     Heart of glass anchors Rasip1 at endothelial cell-cell junctions to
            support vascular integrity
  JOURNAL   Elife 5, e11394 (2016)
   PUBMED   26780829
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3687)
  AUTHORS   Ahmed,S.M., Theriault,B.L., Uppalapati,M., Chiu,C.W., Gallie,B.L.,
            Sidhu,S.S. and Angers,S.
  TITLE     KIF14 negatively regulates Rap1a-Radil signaling during breast
            cancer progression
  JOURNAL   J Cell Biol 199 (6), 951-967 (2012)
   PUBMED   23209302
REFERENCE   3  (bases 1 to 3687)
  AUTHORS   Smolen,G.A., Schott,B.J., Stewart,R.A., Diederichs,S., Muir,B.,
            Provencher,H.L., Look,A.T., Sgroi,D.C., Peterson,R.T. and
            Haber,D.A.
  TITLE     A Rap GTPase interactor, RADIL, mediates migration of neural crest
            precursors
  JOURNAL   Genes Dev 21 (17), 2131-2136 (2007)
   PUBMED   17704304
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On Sep 23, 2014 this sequence version replaced NM_001037218.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.83878.1,
                                           SRR26643295.44525.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-98                JAXUCZ010000012.1  17137872-17137969
            99-697              JAXUCZ010000012.1  17144477-17145075
            698-945             JAXUCZ010000012.1  17178068-17178315
            946-1575            JAXUCZ010000012.1  17179286-17179915
            1576-1613           JAXUCZ010000012.1  17182507-17182544
            1614-1774           JAXUCZ010000012.1  17188366-17188526
            1775-1887           JAXUCZ010000012.1  17191009-17191121
            1888-2125           JAXUCZ010000012.1  17191516-17191753
            2126-2298           JAXUCZ010000012.1  17192096-17192268
            2299-2449           JAXUCZ010000012.1  17198172-17198322
            2450-2640           JAXUCZ010000012.1  17199234-17199424
            2641-2992           JAXUCZ010000012.1  17199707-17200058
            2993-3132           JAXUCZ010000012.1  17200892-17201031
            3133-3272           JAXUCZ010000012.1  17201314-17201453
            3273-3687           JAXUCZ010000012.1  17201607-17202021
FEATURES             Location/Qualifiers
     source          1..3687
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12p11"
     gene            1..3687
                     /gene="Radil"
                     /gene_synonym="RGD1306155"
                     /note="Rap associating with DIL domain"
                     /db_xref="GeneID:304299"
                     /db_xref="RGD:1306155"
     exon            1..98
                     /gene="Radil"
                     /gene_synonym="RGD1306155"
                     /inference="alignment:Splign:2.1.0"
     exon            99..697
                     /gene="Radil"
                     /gene_synonym="RGD1306155"
                     /inference="alignment:Splign:2.1.0"
     CDS             163..3378
                     /gene="Radil"
                     /gene_synonym="RGD1306155"
                     /note="Rap GTPase interactor; Ras association and DIL
                     domains"
                     /codon_start=1
                     /product="ras-associating and dilute domain-containing
                     protein"
                     /protein_id="NP_001032295.2"
                     /db_xref="GeneID:304299"
                     /db_xref="RGD:1306155"
                     /translation="MFYGTQFIMSPPTKNKLKRQSQLLSSMLSRTLSYKYRDLDSTFC
                     SLGASDDPSELSTQLSAPGVLKVFGDSVCTGTHYKSVLATGASSAQELVKEALERYAL
                     DPECASQYVLCDVVGQAGDSGQRWQAQCFRVFGDNEKPLLIQELWKPREGLSRRFELR
                     KKSDVEELAARDVDTTTAGINAQARRLQRIRAKGTPALTSETAQSSPPTGLRRTVSET
                     SLSPTPTLPEAAQRPEEPLPDSMRYSLYQCPHLLLLQGYNQQHDSLVYVLSRERHTVG
                     QRTPSSKPSISLSAPDILPLHCTIRRHQSPDGGPAGTRLVLEPIAGAPVSVNFSEVGR
                     NPVVLQHGDLLSLGLYYLLLFKDPGQAQPLPACALARLGAAPQSCRMCGAALKARGPA
                     SLPAAVVRRRSLFLEFEPDVEDTLLQRIMTLIEPGGDDHKLTPAFLLCLCIQHSATHF
                     QPGTFRHLLLKIAKRIRDTVWEKTKELAEKQAQLQEPISWASFPMADLVPDLQHILFW
                     MSNCIELLYFIQQKSPLYVQSMEEELDVTGSKESLFSCTLTASEEAMAALEEVVLYAF
                     QQCVYYLSKCLYVCLPALLECPPFQTERRESWRSGPALPEELRRVVSVFQATMDLLQQ
                     LQMHPEVASQMLAYLFFFSGTLLLNQVLDKGPSLSCFHWPRGVQVCARLQQFLEWARS
                     AGLGAPAERFFRKLSCTLHLLATPRAQLVQMSWATLRATFPALNPAQLHRLLTQYQLA
                     SAMGPVSAWDPGAQESPEAFQTEDILESYENPPPIVLPSQGFQVDLEADCPEDSIYQH
                     LLYIRHFLWGLRGQASPESGPAQPDSIEGLYHTIPEGHLEGHGCPLTNREQGRGAVET
                     APGHSLPVPGAPRAQGPPGRQPPRGDRRGSQAGSLHTDSSCLLTPPSTPLGLEPGGPT
                     WPEPSGLCGKALLEGQRNGPGGLPGAVLEGDAVQAAAEPPAEASSPSSSTEDFCYVFM
                     VELERGPSGLGMGLIDGMHTPLEAPGLYIQTLLPGSPAASDGRLSLGDQILEVNGSSL
                     MGVSYMRAVDLIRHGGKKMRFLVAKSDMETAKKIRFRKPPS"
     exon            698..945
                     /gene="Radil"
                     /gene_synonym="RGD1306155"
                     /inference="alignment:Splign:2.1.0"
     exon            946..1575
                     /gene="Radil"
                     /gene_synonym="RGD1306155"
                     /inference="alignment:Splign:2.1.0"
     exon            1576..1613
                     /gene="Radil"
                     /gene_synonym="RGD1306155"
                     /inference="alignment:Splign:2.1.0"
     exon            1614..1774
                     /gene="Radil"
                     /gene_synonym="RGD1306155"
                     /inference="alignment:Splign:2.1.0"
     exon            1775..1887
                     /gene="Radil"
                     /gene_synonym="RGD1306155"
                     /inference="alignment:Splign:2.1.0"
     exon            1888..2125
                     /gene="Radil"
                     /gene_synonym="RGD1306155"
                     /inference="alignment:Splign:2.1.0"
     exon            2126..2298
                     /gene="Radil"
                     /gene_synonym="RGD1306155"
                     /inference="alignment:Splign:2.1.0"
     exon            2299..2449
                     /gene="Radil"
                     /gene_synonym="RGD1306155"
                     /inference="alignment:Splign:2.1.0"
     exon            2450..2640
                     /gene="Radil"
                     /gene_synonym="RGD1306155"
                     /inference="alignment:Splign:2.1.0"
     exon            2641..2992
                     /gene="Radil"
                     /gene_synonym="RGD1306155"
                     /inference="alignment:Splign:2.1.0"
     exon            2993..3132
                     /gene="Radil"
                     /gene_synonym="RGD1306155"
                     /inference="alignment:Splign:2.1.0"
     exon            3133..3272
                     /gene="Radil"
                     /gene_synonym="RGD1306155"
                     /inference="alignment:Splign:2.1.0"
     exon            3273..3687
                     /gene="Radil"
                     /gene_synonym="RGD1306155"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgcggccgg caggaggcgc ctggagccgg gcgctagctc ggctaacggc gggcgtggga
       61 gccgcgcgcg ggggacgccg ctgacgggct gcgctgaggc tccagccttc ccccagccac
      121 tggttgaaag cctcagtggt tatttatgag gacgcactca ccatgtttta tgggactcag
      181 ttcatcatgt ctcctcccac caagaataaa ctgaagcgac agagccagct actatcttct
      241 atgctgtccc ggacactgag ctacaagtat cgtgacctag actccacctt ctgcagccta
      301 ggtgccagtg atgacccctc ggagctctcc acgcagctct cagcccctgg ggtcctgaag
      361 gtgtttgggg acagtgtctg tacaggcacc cactataaga gcgtcctggc cactggcgct
      421 tccagcgccc aggagctggt gaaagaggca ctggagcgct atgccctgga tcccgagtgt
      481 gccagccagt atgtgctatg tgatgttgtg ggccaggctg gggactctgg gcagcggtgg
      541 caggcccagt gcttccgagt gtttggggac aatgagaagc ccctcttgat tcaggagtta
      601 tggaagcccc gagaaggctt gtcccggagg tttgagctaa ggaagaagtc agatgtggaa
      661 gagctggcgg cgagggatgt ggataccacc acagcaggga taaacgccca agctcggagg
      721 ctacagcgta tccgtgccaa aggaacccca gccctcacct ctgagactgc ccaaagctcc
      781 ccaccaaccg ggctgcgccg tacagtcagc gagaccagcc taagcccaac accaacgcta
      841 cctgaggctg cccagaggcc tgaggagccc ctccctgaca gcatgcgtta ctcactgtac
      901 cagtgcccgc acctgctgct gttgcagggc tacaaccagc agcacgacag cctggtgtac
      961 gtgctcagcc gggagcggca cacagtgggc cagcgcacgc cctccagcaa acccagcatc
     1021 agcttgtctg ccccagacat cctgcctctg cactgcacca ttcgccgcca ccagtcccca
     1081 gatggtggcc cggcggggac caggctagtg ctggagccca tcgcaggggc accggtgtca
     1141 gtcaacttct cagaagtggg aaggaacccc gtggtgctac aacatggcga cctgctctcc
     1201 ctgggtctct actacctgct gctgttcaag gacccagggc aggcgcagcc actgcctgcc
     1261 tgtgccctcg cccgtcttgg ggcagcaccc cagagctgta gaatgtgtgg tgcggcgctc
     1321 aaagcccgcg ggccggcttc cttgcctgct gctgtggtgc ggcggcggtc actgttcctg
     1381 gagtttgagc ccgacgtgga ggacacactg ctgcagagga tcatgacact gattgagcct
     1441 ggaggggatg accacaagct gacacccgcc ttcctcctct gcctctgcat ccagcactct
     1501 gccactcact tccagccggg taccttcagg catctcctgc tcaagatcgc caaaaggatc
     1561 cgagacactg tctgggagaa gaccaaagaa ctagcagaaa agcaggcgca actgcaggaa
     1621 cccatctcct gggccagctt ccccatggcc gacctggttc ctgacctgca gcacattctc
     1681 ttttggatgt caaactgcat cgaactcctg tacttcatcc aacagaagtc gccactgtac
     1741 gtgcagagca tggaggagga gctggatgtc acaggctcca aggagtcgct gttctcctgc
     1801 acgctgacag ccagtgagga ggccatggcg gccctggagg aggtggtgct gtacgctttc
     1861 cagcagtgtg tgtattacct ctccaagtgc ctgtatgtct gcctcccggc cctcttggaa
     1921 tgccccccat ttcagacaga gcgcagggag agctggcgct cgggccccgc tctgcctgaa
     1981 gagcttcggc gcgtggtgtc ggtgttccag gccaccatgg acctcctgca gcagctgcag
     2041 atgcatcctg aggtggcctc tcagatgctc gcttacctct tcttcttctc tggtacactg
     2101 ctcctcaatc aggtgctgga caaggggccc tccctgagct gcttccactg gcccaggggt
     2161 gtccaggtgt gtgcccgcct gcagcagttt ctggagtggg cccgcagcgc tggcctcgga
     2221 gcacctgccg agcgcttctt tcggaagctt tcctgcaccc tgcatctgct ggccactccc
     2281 cgtgctcagc ttgtccagat gagctgggcc accctacgag ccaccttccc tgccctgaac
     2341 cctgctcagc tgcaccggct gctgactcag taccaactgg cctctgccat gggccctgtg
     2401 agcgcttggg atccaggagc ccaagagagc cctgaggcct tccagacaga ggacatcctg
     2461 gagtcctatg agaacccgcc acccatcgtt ctgccgagcc agggcttcca ggtggacctg
     2521 gaggccgact gcccggagga cagcatctac cagcacctgc tctacatccg ccacttcctg
     2581 tggggactgc ggggccaagc aagccctgag agtgggcctg cccagcctga cagcatcgag
     2641 ggcctgtacc acacaattcc tgaggggcat ctggaaggcc atggctgccc cttgactaat
     2701 agagaacaag gcagaggagc tgtggaaact gctcctggcc attctcttcc tgtgcctgga
     2761 gctccccggg cacagggtcc ccctggaaga cagcctcccc gaggggaccg caggggctcc
     2821 caggctggct ctctgcacac tgactcctcc tgcctgctca ctcctcccag cacaccactg
     2881 ggcctggagc ctggaggccc cacctggcca gagcccagcg gcctctgtgg aaaagcgctc
     2941 ctcgaagggc agaggaatgg accaggtggt cttcctggtg cagttctaga aggagacgcg
     3001 gttcaggctg cggctgagcc tcctgccgag gcctccagcc ccagctccag cacagaggac
     3061 ttctgctacg tgttcatggt ggagctggag cgaggcccct cggggctggg gatgggcctg
     3121 atcgatggca tgcacacacc tctggaggcc ccgggactct acatacagac cttgcttcct
     3181 gggagccccg cggcatctga tggacggctg tccctgggag accaaatcct ggaggtgaac
     3241 ggcagcagcc tgatgggtgt cagctacatg agggcagtgg atctcatccg acatggaggc
     3301 aagaagatgc gatttctggt tgccaagtct gacatggaaa cggccaagaa aatccgcttc
     3361 cgcaaacccc cttcctaata gaccaatgga cccttgcccc caccacctgc ttcctgtatc
     3421 ccctccaggt gcctccaaca gccacccaca gcacccctcg ccctgcccct ccctcactcc
     3481 ccagtccagc cagtcctgag ttgtaaagtt gactgcgtcc ctgtgttgtg gcctcacgtt
     3541 gaggacacct gttgatagtg tgcatcttag tgtatattta tttatatgac agatgacact
     3601 aagttgtgac atttcctaca gagattttat gtttaaaggc tttaatggag aatttagatt
     3661 caataaacta tctttcgtat tcttata
//
