LOCUS       NM_001107029            2556 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus RAD51 paralog D (Rad51d), mRNA.
ACCESSION   NM_001107029 XM_001080997 XM_220773
VERSION     NM_001107029.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2556)
  AUTHORS   Chun,J., Buechelmaier,E.S. and Powell,S.N.
  TITLE     Rad51 paralog complexes BCDX2 and CX3 act at different stages in
            the BRCA1-BRCA2-dependent homologous recombination pathway
  JOURNAL   Mol Cell Biol 33 (2), 387-395 (2013)
   PUBMED   23149936
REFERENCE   2  (bases 1 to 2556)
  AUTHORS   Cappelli,E., Townsend,S., Griffin,C. and Thacker,J.
  TITLE     Homologous recombination proteins are associated with centrosomes
            and are required for mitotic stability
  JOURNAL   Exp Cell Res 317 (8), 1203-1213 (2011)
   PUBMED   21276791
REFERENCE   3  (bases 1 to 2556)
  AUTHORS   Rajesh,C., Baker,D.K., Pierce,A.J. and Pittman,D.L.
  TITLE     The splicing-factor related protein SFPQ/PSF interacts with RAD51D
            and is necessary for homology-directed repair and sister chromatid
            cohesion
  JOURNAL   Nucleic Acids Res 39 (1), 132-145 (2011)
   PUBMED   20813759
REFERENCE   4  (bases 1 to 2556)
  AUTHORS   Compton,S.A., Ozgur,S. and Griffith,J.D.
  TITLE     Ring-shaped Rad51 paralog protein complexes bind Holliday junctions
            and replication forks as visualized by electron microscopy
  JOURNAL   J Biol Chem 285 (18), 13349-13356 (2010)
   PUBMED   20207730
REFERENCE   5  (bases 1 to 2556)
  AUTHORS   Heyer,W.D., Ehmsen,K.T. and Liu,J.
  TITLE     Regulation of homologous recombination in eukaryotes
  JOURNAL   Annu Rev Genet 44, 113-139 (2010)
   PUBMED   20690856
  REMARK    Review article
REFERENCE   6  (bases 1 to 2556)
  AUTHORS   Smiraldo,P.G., Gruver,A.M., Osborn,J.C. and Pittman,D.L.
  TITLE     Extensive chromosomal instability in Rad51d-deficient mouse cells
  JOURNAL   Cancer Res 65 (6), 2089-2096 (2005)
   PUBMED   15781618
REFERENCE   7  (bases 1 to 2556)
  AUTHORS   Tarsounas,M., Munoz,P., Claas,A., Smiraldo,P.G., Pittman,D.L.,
            Blasco,M.A. and West,S.C.
  TITLE     Telomere maintenance requires the RAD51D recombination/repair
            protein
  JOURNAL   Cell 117 (3), 337-347 (2004)
   PUBMED   15109494
REFERENCE   8  (bases 1 to 2556)
  AUTHORS   Kurumizaka,H., Ikawa,S., Nakada,M., Enomoto,R., Kagawa,W.,
            Kinebuchi,T., Yamazoe,M., Yokoyama,S. and Shibata,T.
  TITLE     Homologous pairing and ring and filament structure formation
            activities of the human Xrcc2*Rad51D complex
  JOURNAL   J Biol Chem 277 (16), 14315-14320 (2002)
   PUBMED   11834724
REFERENCE   9  (bases 1 to 2556)
  AUTHORS   Masson,J.Y., Tarsounas,M.C., Stasiak,A.Z., Stasiak,A., Shah,R.,
            McIlwraith,M.J., Benson,F.E. and West,S.C.
  TITLE     Identification and purification of two distinct complexes
            containing the five RAD51 paralogs
  JOURNAL   Genes Dev 15 (24), 3296-3307 (2001)
   PUBMED   11751635
REFERENCE   10 (bases 1 to 2556)
  AUTHORS   Braybrooke,J.P., Spink,K.G., Thacker,J. and Hickson,I.D.
  TITLE     The RAD51 family member, RAD51L3, is a DNA-stimulated ATPase that
            forms a complex with XRCC2
  JOURNAL   J Biol Chem 275 (37), 29100-29106 (2000)
   PUBMED   10871607
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC169062.1.
            
            On Sep 4, 2008 this sequence version replaced NM_001107029.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC169062.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2556
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q26"
     gene            1..2556
                     /gene="Rad51d"
                     /gene_synonym="Rad51l3"
                     /note="RAD51 paralog D"
                     /db_xref="GeneID:303375"
                     /db_xref="RGD:1306944"
     exon            1..203
                     /gene="Rad51d"
                     /gene_synonym="Rad51l3"
                     /inference="alignment:Splign:2.1.0"
     CDS             122..1111
                     /gene="Rad51d"
                     /gene_synonym="Rad51l3"
                     /codon_start=1
                     /product="DNA repair protein RAD51 homolog 4"
                     /protein_id="NP_001100499.1"
                     /db_xref="GeneID:303375"
                     /db_xref="RGD:1306944"
                     /translation="MGMLRAGLCPGLTEEIVQLLRGRKIKTVADLAAADLEEVAQKCG
                     LSYKALVALRRVLLAQFSAFPLNGADLYEELKTSTAILSTGIGSLDKLLDAGLYTGEL
                     TEIVGGPGSGKTQVCLCVAANVAHSLQQNVLYVDSNGGMTASRLLQLLQARTQDEEKQ
                     ASALQRIQVVHSFDIFQMLDMLQDLRGTMAQQATASSGTVKVVIVDSVTAVVAPLLGG
                     QQREGLALMMQLARELKILARDLGVAVVVTNHLTRDRDSRRFKPALGRSWSFVPSTRI
                     LLEVFEGAGTLGRSQRTVRLIKSPRQPTGLQEVIDIGTLGTEEQSPELPGKQT"
     exon            204..265
                     /gene="Rad51d"
                     /gene_synonym="Rad51l3"
                     /inference="alignment:Splign:2.1.0"
     exon            266..384
                     /gene="Rad51d"
                     /gene_synonym="Rad51l3"
                     /inference="alignment:Splign:2.1.0"
     exon            385..466
                     /gene="Rad51d"
                     /gene_synonym="Rad51l3"
                     /inference="alignment:Splign:2.1.0"
     exon            467..601
                     /gene="Rad51d"
                     /gene_synonym="Rad51l3"
                     /inference="alignment:Splign:2.1.0"
     exon            602..697
                     /gene="Rad51d"
                     /gene_synonym="Rad51l3"
                     /inference="alignment:Splign:2.1.0"
     exon            698..788
                     /gene="Rad51d"
                     /gene_synonym="Rad51l3"
                     /inference="alignment:Splign:2.1.0"
     exon            789..859
                     /gene="Rad51d"
                     /gene_synonym="Rad51l3"
                     /inference="alignment:Splign:2.1.0"
     exon            860..1027
                     /gene="Rad51d"
                     /gene_synonym="Rad51l3"
                     /inference="alignment:Splign:2.1.0"
     exon            1028..2541
                     /gene="Rad51d"
                     /gene_synonym="Rad51l3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtccctcgct agcacgggag gaccttttcc ttaagtggaa ctgaggaatg cctagagtgg
       61 gggactcggc gggcgcccac gtgacagaca gcccccaggg cgtcctgggt ttgcagggaa
      121 tatgggcatg ctcagggcag ggctgtgccc gggcctcacc gaggagatcg tccagcttct
      181 gaggggccga aagatcaaaa cagtggcaga cctggcagct gctgacttgg aggaggtagc
      241 ccagaagtgt ggtctgtcct acaaggccct ggttgccctg aggagagtgt tgctggcgca
      301 gttctcggct ttccccttaa atggtgcaga tctctatgag gaactgaaga cttccactgc
      361 catcctgtcc accggcatcg gaagcctgga caaactactt gatgctggcc tctatactgg
      421 ggagctgact gaaattgtgg gtggcccagg tagtggcaaa actcaggtgt gtctctgtgt
      481 ggctgcaaat gtggcccaca gcctgcaaca gaatgtactg tatgtggatt ccaatggagg
      541 aatgacagcg tcccgcctcc tccagctact acaagctaga acccaagatg aggagaaaca
      601 ggcaagtgct ctccagagga tacaggtggt gcattcattt gacatcttcc agatgttaga
      661 catgctgcag gaccttaggg gcaccatggc ccagcaggcg acagcttctt caggcactgt
      721 gaaggttgtg attgtggatt ctgtcactgc agtggtcgcc ccacttctgg gaggtcagca
      781 gagggaaggc ctggccttga tgatgcagct ggcccgagag ctcaagatcc tggctcggga
      841 cctgggtgtg gcagtggtgg taaccaacca cttgactcga gacagggaca gtagaagatt
      901 caaacctgcc cttggacgct cctggagctt tgtgcccagt acccggattc tcctggaagt
      961 ctttgaggga gctggaacac taggccgcag ccaacgcaca gtacgtctga tcaagtctcc
     1021 ccgccagcca acgggtctgc aggaggtgat agacattggg acattgggga ctgaggagca
     1081 gagcccagaa ttgcctggca aacagacgtg acacagttga ctgggaaagg gacagtctca
     1141 aggccctcac agctttcctt cccaggcagc tgctgtccgc tgccacatga gacccggcag
     1201 tgcagatgtc tcaggctcat cagaagacaa gcctcagttc ccttagcttc actgtttggg
     1261 atctctggag ccattggcca gaggttgctg cagtaggaga ggcctagaag tccatcgggg
     1321 tctcaagttg cctttggatc cactgaatgt ctccagtgtg ggttaatgtc aacctagctt
     1381 gaggcctcac tgaagaagca cagtactacc tacatgaata gcttcgtggt cctgtgtgtc
     1441 accattggct cctaaaccca tccctcacac agtaattgag caggaagcct ttgctccccc
     1501 atcccccatt cattttggcc tctgttttcc catctgcaag atggcacttc cttagtctgg
     1561 gagttactca gtagaaacaa cctccaaaat gtaaacctct ttatgcttgt cctactctta
     1621 aaatatgtaa acaaggaggc cctctgagcc ctgaagccac ctgatttccc ccaaggttgt
     1681 ttttcagttt ctgcagtggg actcccagag aatgagagtg cttccttccc tgcttgctga
     1741 ctgggtttca cacacctgca tacctcaccc tgataggtga gaccatagct cgctgctgtc
     1801 ccagggatat aatttatcag ggaggaagga tatgacctgc tcccagtgag ccagacactt
     1861 gtttcatatg catggtgccc tgtggggtgc ttcctcagta tagagtaacc agaggtgctg
     1921 aaccatggcc taacccataa acagacacag gagaatttgc acagtaaata gagccagctg
     1981 ggaaaattga tgccggcgta aataatacat ggcaaatcta gtcttttata cagaaattca
     2041 ttgctggtgg ctctaagatg tagtataatt acacctctca tcctgccagc tgtaccacag
     2101 cctcgtgtct tagtgaataa aataaccctc tgtctgttac caacactgtg gccatccatc
     2161 tgagagtcat aactctggct gaaaggggag gatgggacca gggaatggaa aataaaaggc
     2221 agggagaaat gatctggatt gtttatgaag caagagtttt tacaggaagg tcatgcttgg
     2281 ttagagagcc tgttgtacaa ttactcgtgt cttagctgaa ggaaagagga aacatagtta
     2341 caagacctga tatttagggc cagtgggatg gctcagcaaa taaagatgct tgccgccaag
     2401 cctgacaccc aagttcaatc ccagggtcct acataaggga aagagagatg tgactcttgt
     2461 aagttgtcct ccgacagtcc atatatacta tggcctatct gtaccccctc ccacatgata
     2521 ataaaaaaat ctaataaaga aaaaaaaaaa aaaaaa
//
