LOCUS       NM_001399175            1535 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus RAD51 paralog B (Rad51b), mRNA.
ACCESSION   NM_001399175 XM_039113280
VERSION     NM_001399175.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1535)
  AUTHORS   Rodrigue,A., Coulombe,Y., Jacquet,K., Gagne,J.P., Roques,C.,
            Gobeil,S., Poirier,G. and Masson,J.Y.
  TITLE     The RAD51 paralogs ensure cellular protection against mitotic
            defects and aneuploidy
  JOURNAL   J Cell Sci 126 (Pt 1), 348-359 (2013)
   PUBMED   23108668
REFERENCE   2  (bases 1 to 1535)
  AUTHORS   Chun,J., Buechelmaier,E.S. and Powell,S.N.
  TITLE     Rad51 paralog complexes BCDX2 and CX3 act at different stages in
            the BRCA1-BRCA2-dependent homologous recombination pathway
  JOURNAL   Mol Cell Biol 33 (2), 387-395 (2013)
   PUBMED   23149936
REFERENCE   3  (bases 1 to 1535)
  AUTHORS   Compton,S.A., Ozgur,S. and Griffith,J.D.
  TITLE     Ring-shaped Rad51 paralog protein complexes bind Holliday junctions
            and replication forks as visualized by electron microscopy
  JOURNAL   J Biol Chem 285 (18), 13349-13356 (2010)
   PUBMED   20207730
REFERENCE   4  (bases 1 to 1535)
  AUTHORS   Heyer,W.D., Ehmsen,K.T. and Liu,J.
  TITLE     Regulation of homologous recombination in eukaryotes
  JOURNAL   Annu Rev Genet 44, 113-139 (2010)
   PUBMED   20690856
  REMARK    Review article
REFERENCE   5  (bases 1 to 1535)
  AUTHORS   Yokoyama,H., Kurumizaka,H., Ikawa,S., Yokoyama,S. and Shibata,T.
  TITLE     Holliday junction binding activity of the human Rad51B protein
  JOURNAL   J Biol Chem 278 (4), 2767-2772 (2003)
   PUBMED   12441335
REFERENCE   6  (bases 1 to 1535)
  AUTHORS   Masson,J.Y., Tarsounas,M.C., Stasiak,A.Z., Stasiak,A., Shah,R.,
            McIlwraith,M.J., Benson,F.E. and West,S.C.
  TITLE     Identification and purification of two distinct complexes
            containing the five RAD51 paralogs
  JOURNAL   Genes Dev 15 (24), 3296-3307 (2001)
   PUBMED   11751635
REFERENCE   7  (bases 1 to 1535)
  AUTHORS   Shu,Z., Smith,S., Wang,L., Rice,M.C. and Kmiec,E.B.
  TITLE     Disruption of muREC2/RAD51L1 in mice results in early embryonic
            lethality which can Be partially rescued in a p53(-/-) background
  JOURNAL   Mol Cell Biol 19 (12), 8686-8693 (1999)
   PUBMED   10567591
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Jan 4, 2022 this sequence version replaced XM_039113280.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643292.26497.1,
                                           SRR26360190.3052993.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-34                JAXUCZ010000006.1  103829554-103829587
            35-140              JAXUCZ010000006.1  103832551-103832656
            141-254             JAXUCZ010000006.1  103834512-103834625
            255-371             JAXUCZ010000006.1  103837311-103837427
            372-508             JAXUCZ010000006.1  103856506-103856642
            509-628             JAXUCZ010000006.1  103867548-103867667
            629-812             JAXUCZ010000006.1  103869571-103869754
            813-909             JAXUCZ010000006.1  104211472-104211568
            910-1013            JAXUCZ010000006.1  104325905-104326008
            1014-1092           JAXUCZ010000006.1  104363269-104363347
            1093-1535           JAXUCZ010000006.1  104373481-104373923
FEATURES             Location/Qualifiers
     source          1..1535
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q24"
     gene            1..1535
                     /gene="Rad51b"
                     /gene_synonym="Rad51l1; RGD1560681"
                     /note="RAD51 paralog B"
                     /db_xref="GeneID:500679"
                     /db_xref="RGD:1560681"
     exon            1..34
                     /gene="Rad51b"
                     /gene_synonym="Rad51l1; RGD1560681"
                     /inference="alignment:Splign:2.1.0"
     exon            35..140
                     /gene="Rad51b"
                     /gene_synonym="Rad51l1; RGD1560681"
                     /inference="alignment:Splign:2.1.0"
     CDS             57..1109
                     /gene="Rad51b"
                     /gene_synonym="Rad51l1; RGD1560681"
                     /note="RAD51-like 1; RAD51 homolog B"
                     /codon_start=1
                     /product="DNA repair protein RAD51 homolog 2"
                     /protein_id="NP_001386104.1"
                     /db_xref="GeneID:500679"
                     /db_xref="RGD:1560681"
                     /translation="MSSKKLRRAGLSQELCDRLCRYQIVNCQDFLNLSPLELMKVTGL
                     SYRGVHELLHTVSKACAPQMQTAYELKTRRSAHLSPAFLSTTLGALDEALHGGVPCGS
                     LTEVTGPPGCGKTQFCIMMSVLATLPTRLGGLEGAVLYIDTESAFTAERLVEIAESRF
                     PQYFNTEEKLLLTSSRVHLCQELTCEGLLQRLESLEEEIISKGVKLVIVDSIASVVRK
                     EFDPQLQGNIKERNKFLGKGASLLKYLSGEFSVPVILTNQITTHLSGALPSQADLVSP
                     ADDLSPSEGASGSSCLVAALGNTWSHCVNTRLILQYLDSERRQILIAKSPVAPLTSFV
                     YTIKGEGLVLQGQERP"
     exon            141..254
                     /gene="Rad51b"
                     /gene_synonym="Rad51l1; RGD1560681"
                     /inference="alignment:Splign:2.1.0"
     exon            255..371
                     /gene="Rad51b"
                     /gene_synonym="Rad51l1; RGD1560681"
                     /inference="alignment:Splign:2.1.0"
     exon            372..508
                     /gene="Rad51b"
                     /gene_synonym="Rad51l1; RGD1560681"
                     /inference="alignment:Splign:2.1.0"
     exon            509..628
                     /gene="Rad51b"
                     /gene_synonym="Rad51l1; RGD1560681"
                     /inference="alignment:Splign:2.1.0"
     exon            629..812
                     /gene="Rad51b"
                     /gene_synonym="Rad51l1; RGD1560681"
                     /inference="alignment:Splign:2.1.0"
     exon            813..909
                     /gene="Rad51b"
                     /gene_synonym="Rad51l1; RGD1560681"
                     /inference="alignment:Splign:2.1.0"
     exon            910..1013
                     /gene="Rad51b"
                     /gene_synonym="Rad51l1; RGD1560681"
                     /inference="alignment:Splign:2.1.0"
     exon            1014..1092
                     /gene="Rad51b"
                     /gene_synonym="Rad51l1; RGD1560681"
                     /inference="alignment:Splign:2.1.0"
     exon            1093..1535
                     /gene="Rad51b"
                     /gene_synonym="Rad51l1; RGD1560681"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tggggaactt tgaaatttct acgctgctga cctgattctt tgggaaacct ggaaatatga
       61 gcagcaagaa actgaggagg gcgggtttgt ctcaagagct gtgtgaccgt ttatgcagat
      121 atcagattgt taactgtcag gactttttaa atctctcccc actagaactt atgaaagtca
      181 ctggcctgag ttatagaggt gtccacgagc ttctgcatac agtaagcaag gcctgtgccc
      241 cacagatgca aacggcttat gagttaaaga cacgaaggtc tgcacatctc tcaccagcgt
      301 tcctatctac tacccttggt gctttggatg aagcactgca tggtggtgtg ccttgtggat
      361 ctctcacaga ggttacaggt ccaccaggtt gtgggaagac ccagttttgc ataatgatga
      421 gtgtcttagc tacattaccc acccgcctgg gaggattgga aggggcggtg ctgtacattg
      481 acacagagtc tgcgtttact gctgagagac tggtcgagat cgcagaatcc cgctttccac
      541 agtattttaa cactgaggaa aagttgcttc tgaccagcag tagagttcat ctttgccaag
      601 aactcacctg tgagggactt ctgcaaaggc ttgaatcttt ggaggaagag atcatttcga
      661 aaggagttaa gcttgtgatt gtggactcca ttgcttctgt ggtcagaaag gagtttgacc
      721 cgcagcttca aggcaacatc aaagaaagga acaagttctt gggcaaagga gcgtccttac
      781 tgaagtacct gtctggggag ttttcagtcc cagttatctt gacgaatcaa attacgaccc
      841 atctgagtgg agccctccct tctcaagcag acctggtgtc tccagctgat gatttgtccc
      901 cgtctgaagg cgcctctgga tccagctgtt tggtagcggc actgggaaac acatggagtc
      961 actgtgtgaa cacccggctg attctccagt acctagattc agagagaagg cagattctca
     1021 tcgccaagtc ccctgtggct cccctcacct cctttgtcta caccatcaag ggggaaggcc
     1081 tggtccttca aggccaagaa aggccatagg gatactgtga cctttgtcta gtgctgatgg
     1141 gatgtgattt gtgaaatgaa acaggactgt gctgcttgga aaaaaggaaa cggaagccaa
     1201 cataatgagg attaattggc tgattgctgt tgagatggta acagtgattt cagacctgga
     1261 agggaaggtg aagatgaaga agcctttgtc cggtctctag atgtggaggc tagcggctcc
     1321 accaccgtgg gatgtcagca gccataataa taatttgcac ttacacagca cctttcaacc
     1381 atgcacctca aagcggttta gccacattaa ttaattaaaa cccacaatcc ccctagggag
     1441 aggaggaggg ggactaacaa gatttgtaat tacaaaaggg aacatttccg aataaagtat
     1501 tgtccagcaa ataaaaagaa taggtgtaca aagaa
//
