LOCUS       NP_001102674             339 aa            linear   ROD 23-MAR-2023
DEFINITION  DNA repair protein RAD51 homolog 1 [Rattus norvegicus].
ACCESSION   NP_001102674 XP_001075212 XP_575211
VERSION     NP_001102674.1
DBSOURCE    REFSEQ: accession NM_001109204.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 339)
  AUTHORS   Ding YC, Adamson AW, Steele L, Bailis AM, John EM, Tomlinson G and
            Neuhausen SL.
  TITLE     Discovery of mutations in homologous recombination genes in
            African-American women with breast cancer
  JOURNAL   Fam Cancer 17 (2), 187-195 (2018)
   PUBMED   28864920
REFERENCE   2  (residues 1 to 339)
  AUTHORS   Finsterbusch F, Ravindranathan R, Dereli I, Stanzione M, Trankner D
            and Toth A.
  TITLE     Alignment of Homologous Chromosomes and Effective Repair of
            Programmed DNA Double-Strand Breaks during Mouse Meiosis Require
            the Minichromosome Maintenance Domain Containing 2 (MCMDC2) Protein
  JOURNAL   PLoS Genet 12 (10), e1006393 (2016)
   PUBMED   27760146
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 339)
  AUTHORS   Sun X, Brieno-Enriquez MA, Cornelius A, Modzelewski AJ, Maley TT,
            Campbell-Peterson KM, Holloway JK and Cohen PE.
  TITLE     FancJ (Brip1) loss-of-function allele results in spermatogonial
            cell depletion during embryogenesis and altered processing of
            crossover sites during meiotic prophase I in mice
  JOURNAL   Chromosoma 125 (2), 237-252 (2016)
   PUBMED   26490168
REFERENCE   4  (residues 1 to 339)
  AUTHORS   Ameziane N, May P, Haitjema A, van de Vrugt HJ, van Rossum-Fikkert
            SE, Ristic D, Williams GJ, Balk J, Rockx D, Li H, Rooimans MA,
            Oostra AB, Velleuer E, Dietrich R, Bleijerveld OB, Maarten Altelaar
            AF, Meijers-Heijboer H, Joenje H, Glusman G, Roach J, Hood L, Galas
            D, Wyman C, Balling R, den Dunnen J, de Winter JP, Kanaar R,
            Gelinas R and Dorsman JC.
  TITLE     A novel Fanconi anaemia subtype associated with a dominant-negative
            mutation in RAD51
  JOURNAL   Nat Commun 6, 8829 (2015)
   PUBMED   26681308
  REMARK    Publication Status: Online-Only
REFERENCE   5  (residues 1 to 339)
  AUTHORS   Parplys AC, Zhao W, Sharma N, Groesser T, Liang F, Maranon DG,
            Leung SG, Grundt K, Dray E, Idate R, Ostvold AC, Schild D, Sung P
            and Wiese C.
  TITLE     NUCKS1 is a novel RAD51AP1 paralog important for homologous
            recombination and genome stability
  JOURNAL   Nucleic Acids Res 43 (20), 9817-9834 (2015)
   PUBMED   26323318
REFERENCE   6  (residues 1 to 339)
  AUTHORS   Kovalenko OV, Golub EI, Bray-Ward P, Ward DC and Radding CM.
  TITLE     A novel nucleic acid-binding protein that interacts with human
            rad51 recombinase
  JOURNAL   Nucleic Acids Res 25 (24), 4946-4953 (1997)
   PUBMED   9396801
REFERENCE   7  (residues 1 to 339)
  AUTHORS   Moens PB, Chen DJ, Shen Z, Kolas N, Tarsounas M, Heng HH and
            Spyropoulos B.
  TITLE     Rad51 immunocytology in rat and mouse spermatocytes and oocytes
  JOURNAL   Chromosoma 106 (4), 207-215 (1997)
   PUBMED   9254722
REFERENCE   8  (residues 1 to 339)
  AUTHORS   Baumann P, Benson FE and West SC.
  TITLE     Human Rad51 protein promotes ATP-dependent homologous pairing and
            strand transfer reactions in vitro
  JOURNAL   Cell 87 (4), 757-766 (1996)
   PUBMED   8929543
REFERENCE   9  (residues 1 to 339)
  AUTHORS   Li MJ, Peakman MC, Golub EI, Reddy G, Ward DC, Radding CM and
            Maizels N.
  TITLE     Rad51 expression and localization in B cells carrying out class
            switch recombination
  JOURNAL   Proc Natl Acad Sci U S A 93 (19), 10222-10227 (1996)
   PUBMED   8816780
REFERENCE   10 (residues 1 to 339)
  AUTHORS   Benson FE, Stasiak A and West SC.
  TITLE     Purification and characterization of the human Rad51 protein, an
            analogue of E. coli RecA
  JOURNAL   EMBO J 13 (23), 5764-5771 (1994)
   PUBMED   7988572
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473949.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XP_575211.1, XP_001075212.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168875.1, SRR8487231.180683.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q35"
     Protein         1..339
                     /product="DNA repair protein RAD51 homolog 1"
                     /note="RAD51 homolog"
                     /calculated_mol_wt=36837
     Region          25..339
                     /region_name="recomb_RAD51"
                     /note="DNA repair protein RAD51; TIGR02239"
                     /db_xref="CDD:274048"
     CDS             1..339
                     /gene="Rad51"
                     /gene_synonym="RGD1563603"
                     /coded_by="NM_001109204.1:218..1237"
                     /db_xref="GeneID:499870"
                     /db_xref="RGD:1563603"
ORIGIN      
        1 mamqmqlean adtsveeesf gpqpisrleq cginandvkk leeagyhtve avayapkkel
       61 inikgiseak adkilaeaak lvpmgfttat efhqrrseii qittgskeld kllqggietg
      121 sitemfgefr tgktqichtl avtcqlpidr gggegkamyi dtegtfrper llavaerygl
      181 sgsdvldnva yargfntdhq tqllyqasam mvesryalli vdsatalyrt dysgrgelsa
      241 rqmhlarflr mllrladefg vavvitnqvv aqvdgaamfa adpkkpiggn iiahasttrl
      301 ylrkgrgetr ickiydspcl peaeamfain adgvgdakd
//
