LOCUS       NM_001399101            1857 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus RAD23 homolog A, nucleotide excision repair
            protein (Rad23a), transcript variant 2, mRNA.
ACCESSION   NM_001399101 XM_006255276
VERSION     NM_001399101.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1857)
  AUTHORS   Tan,X., Liang,R.Y. and Chuang,S.M.
  TITLE     hHR23A is required to control the basal turnover of Chk1
  JOURNAL   Cell Signal 27 (11), 2304-2313 (2015)
   PUBMED   26296656
REFERENCE   2  (bases 1 to 1857)
  AUTHORS   Laco,M.N., Cortes,L., Travis,S.M., Paulson,H.L. and Rego,A.C.
  TITLE     Valosin-containing protein (VCP/p97) is an activator of wild-type
            ataxin-3
  JOURNAL   PLoS One 7 (9), e43563 (2012)
   PUBMED   22970133
REFERENCE   3  (bases 1 to 1857)
  AUTHORS   Li,G., Elder,R.T., Dubrovsky,L., Liang,D., Pushkarsky,T., Chiu,K.,
            Fan,T., Sire,J., Bukrinsky,M. and Zhao,R.Y.
  TITLE     HIV-1 replication through hHR23A-mediated interaction of Vpr with
            26S proteasome
  JOURNAL   PLoS One 5 (6), e11371 (2010)
   PUBMED   20614012
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1857)
  AUTHORS   Ng,J.M., Vermeulen,W., van der Horst,G.T., Bergink,S., Sugasawa,K.,
            Vrieling,H. and Hoeijmakers,J.H.
  TITLE     A novel regulation mechanism of DNA repair by damage-induced and
            RAD23-dependent stabilization of xeroderma pigmentosum group C
            protein
  JOURNAL   Genes Dev 17 (13), 1630-1645 (2003)
   PUBMED   12815074
REFERENCE   5  (bases 1 to 1857)
  AUTHORS   Raasi,S. and Pickart,C.M.
  TITLE     Rad23 ubiquitin-associated domains (UBA) inhibit 26 S
            proteasome-catalyzed proteolysis by sequestering lysine 48-linked
            polyubiquitin chains
  JOURNAL   J Biol Chem 278 (11), 8951-8959 (2003)
   PUBMED   12643283
REFERENCE   6  (bases 1 to 1857)
  AUTHORS   Sugasawa,K., Ng,J.M., Masutani,C., Maekawa,T., Uchida,A., van der
            Spek,P.J., Eker,A.P., Rademakers,S., Visser,C., Aboussekhra,A.,
            Wood,R.D., Hanaoka,F., Bootsma,D. and Hoeijmakers,J.H.
  TITLE     Two human homologs of Rad23 are functionally interchangeable in
            complex formation and stimulation of XPC repair activity
  JOURNAL   Mol Cell Biol 17 (12), 6924-6931 (1997)
   PUBMED   9372924
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000019.1.
            
            On Jan 4, 2022 this sequence version replaced XM_006255276.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360181.2926426.1,
                                           SRR26360186.355365.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-159               JAXUCZ010000019.1  40219636-40219794
            160-321             JAXUCZ010000019.1  40221384-40221545
            322-503             JAXUCZ010000019.1  40221686-40221867
            504-559             JAXUCZ010000019.1  40221999-40222054
            560-687             JAXUCZ010000019.1  40222186-40222313
            688-766             JAXUCZ010000019.1  40222549-40222627
            767-900             JAXUCZ010000019.1  40222719-40222852
            901-1065            JAXUCZ010000019.1  40224508-40224672
            1066-1857           JAXUCZ010000019.1  40224752-40225543
FEATURES             Location/Qualifiers
     source          1..1857
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q11"
     gene            1..1857
                     /gene="Rad23a"
                     /note="RAD23 homolog A, nucleotide excision repair
                     protein"
                     /db_xref="GeneID:361381"
                     /db_xref="RGD:1309899"
     exon            1..159
                     /gene="Rad23a"
                     /inference="alignment:Splign:2.1.0"
     CDS             88..1179
                     /gene="Rad23a"
                     /note="isoform 2 is encoded by transcript variant 2; UV
                     excision repair protein RAD23 homolog A"
                     /codon_start=1
                     /product="UV excision repair protein RAD23 homolog A
                     isoform 2"
                     /protein_id="NP_001386030.1"
                     /db_xref="GeneID:361381"
                     /db_xref="RGD:1309899"
                     /translation="MAVTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGRDAFPVA
                     GQKLIYAGKILSDDIPIKEYHIDEKNFVVVMVTKAKAGQGTPAPPEASPTAAPEPSTP
                     FPPAPASGMSHPPPSNREDKSSSEESATTTSPESISGSVPSSGSSGREEDAASTLVTG
                     SEYETMLTEIMSMGYERERVVAALRASYNNPHRAVEYLLTGIPGSPEPEHGSVQESQA
                     PEQPATEAAGENPLEFLRDQPQFQNMRQVIQQNPALLPALLQQLGQENPQLLQQISRH
                     QEQFIQMLNEPPGELADISDVEGEVGALGEEAPQMNYIQVTPQEKEAIERLKALGFPE
                     SLVIQAYFACEKNENLAANFLLSQNFDDE"
     exon            160..321
                     /gene="Rad23a"
                     /inference="alignment:Splign:2.1.0"
     exon            322..503
                     /gene="Rad23a"
                     /inference="alignment:Splign:2.1.0"
     exon            504..559
                     /gene="Rad23a"
                     /inference="alignment:Splign:2.1.0"
     exon            560..687
                     /gene="Rad23a"
                     /inference="alignment:Splign:2.1.0"
     exon            688..766
                     /gene="Rad23a"
                     /inference="alignment:Splign:2.1.0"
     exon            767..900
                     /gene="Rad23a"
                     /inference="alignment:Splign:2.1.0"
     exon            901..1065
                     /gene="Rad23a"
                     /inference="alignment:Splign:2.1.0"
     exon            1066..1857
                     /gene="Rad23a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggcgcggc tgggcgctaa gatggcggcg gcgtgagttg catgttgtgc gaggatcccg
       61 gggctgccgc attgctccgg ccccgccatg gccgtcacca tcacacttaa aacgttgcag
      121 cagcagacct tcaagatccg catggaacct gatgagacgg tgaaggtgct gaaggagaag
      181 atagaagctg agaagggcag agatgctttc cctgtggctg gacagaaact catctatgct
      241 ggcaagatct tgagtgacga cattcccatc aaggaatacc atatagatga gaagaacttt
      301 gtggttgtca tggtgaccaa ggccaaggct ggtcagggta ccccagcacc cccagaggcc
      361 tcacccactg ctgccccgga gccctccaca ccttttcctc cagccccagc atccggcatg
      421 tctcatcctc caccttccaa cagagaggac aagagctcat cagaggagtc agccaccaca
      481 acgtctccag aatccatttc tggctctgtt ccctcttcag gtagcagcgg gcgagaggaa
      541 gacgcagctt ccacattagt gactggctct gagtatgaga cgatgctgac tgagatcatg
      601 tccatgggct acgagcggga gcgggttgtg gccgcattga gggccagcta caacaacccc
      661 caccgagccg tggagtactt gctcacggga attccaggaa gccctgagcc tgaacatggt
      721 tctgtccagg aaagccaggc gcccgaacaa ccggccacag aagcagcagg ggagaacccc
      781 ctagagttcc tgcgggacca gcctcagttc cagaacatgc ggcaagtgat tcagcagaac
      841 ccggcgctgc tgcctgctct gctccagcag ctgggccagg agaaccctca gctcttgcag
      901 caaattagcc gtcaccagga gcagttcatc cagatgttga atgagccccc cggggagctg
      961 gcggacatct ctgatgtaga gggggaggtt ggtgccctag gtgaggaggc cccacagatg
     1021 aactatatcc aggtgacacc gcaggagaag gaagctatag aaaggctgaa ggcactgggc
     1081 ttcccggaga gcctggtgat ccaggcctac ttcgcgtgtg agaaaaatga gaacttggct
     1141 gccaacttcc tcctgagtca gaactttgat gatgagtgat gctgggaggc tagaaggccc
     1201 ccaccccact ccacaaaagt ttataagaga aaagtatata tatatatata tatatatata
     1261 tatatatata tatatatata tatatatata tatatatata tatctcacat atatatatat
     1321 tcatgtttat ttaagaggaa gaaaaatcaa aaaccattaa aaaaaacaaa aaaaacaacc
     1381 cacccagccc agcttcctac cctcctgaag tggcccctat tcccatctgt ctgagaagac
     1441 ctgggccaca cagctgtccc tatcctctca acagagccca gcctgcccaa agttgttggc
     1501 aagaccagga agcgacagat gggcccctct tggcctctgt cccagctccc tgtagccaga
     1561 tggagaggcg cctgcctgtt tccccagccc ctgaagcatc cccaaggaca accctccttc
     1621 ctctaccatg aggggaagct ggagccctaa acctttatct ccattggagt ggccccgatc
     1681 ttcccatctg gagtaaggct gttagaagcc caaggccttc tccccagtct cgccttggcc
     1741 tccagcctgg aaaaggggta acatcagttc tgaaggccaa ggccacccct tccccaggac
     1801 agaaacacct ctgataaagg ttttgaagtg aataaagttt taaaaaatga gccctaa
//
