LOCUS       NM_001108319            1961 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus RAB, member of RAS oncogene family-like 3
            (Rabl3), mRNA.
ACCESSION   NM_001108319 XM_001061761 XM_001061873 XM_001061934 XM_340992
VERSION     NM_001108319.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1961)
  AUTHORS   Nissim S, Leshchiner I, Mancias JD, Greenblatt MB, Maertens O,
            Cassa CA, Rosenfeld JA, Cox AG, Hedgepeth J, Wucherpfennig JI, Kim
            AJ, Henderson JE, Gonyo P, Brandt A, Lorimer E, Unger B, Prokop JW,
            Heidel JR, Wang XX, Ukaegbu CI, Jennings BC, Paulo JA, Gableske S,
            Fierke CA, Getz G, Sunyaev SR, Wade Harper J, Cichowski K,
            Kimmelman AC, Houvras Y, Syngal S, Williams C and Goessling W.
  TITLE     Mutations in RABL3 alter KRAS prenylation and are associated with
            hereditary pancreatic cancer
  JOURNAL   Nat Genet 51 (9), 1308-1314 (2019)
   PUBMED   31406347
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473967.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_340992.3, XM_001061934.1, XM_001061761.1, XM_001061873.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ230436.1, FN806009.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1961
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q21"
     gene            1..1961
                     /gene="Rabl3"
                     /note="RAB, member of RAS oncogene family-like 3"
                     /db_xref="GeneID:360720"
                     /db_xref="RGD:1306436"
     exon            1..62
                     /gene="Rabl3"
                     /inference="alignment:Splign:2.1.0"
     CDS             17..727
                     /gene="Rabl3"
                     /codon_start=1
                     /product="rab-like protein 3"
                     /protein_id="NP_001101789.1"
                     /db_xref="GeneID:360720"
                     /db_xref="RGD:1306436"
                     /translation="MASLDRVKVLVLGDSGVGKSSLVHLLCHNQVLGNPSWTVGCSVD
                     IRVHDYKEGTPEEKTYYIELWDVGGSVGSASSVKSTRAVFYNSVNGIILVHDLTNKKS
                     SQNLYRWSLEVLNRDAVPTGVLVTNGDYDREQFADNQIPLLVIGTKLDQIHETKRHEV
                     LIRTAFLAEDFNAEEINLDCTNPRSSAAGSSNAVKLSRFFDKVIEKRYLFREGNQIPG
                     FSDRKRFGGGTLKNFHCD"
     exon            63..154
                     /gene="Rabl3"
                     /inference="alignment:Splign:2.1.0"
     exon            155..284
                     /gene="Rabl3"
                     /inference="alignment:Splign:2.1.0"
     exon            285..399
                     /gene="Rabl3"
                     /inference="alignment:Splign:2.1.0"
     exon            400..550
                     /gene="Rabl3"
                     /inference="alignment:Splign:2.1.0"
     exon            551..622
                     /gene="Rabl3"
                     /inference="alignment:Splign:2.1.0"
     exon            623..661
                     /gene="Rabl3"
                     /inference="alignment:Splign:2.1.0"
     exon            662..1961
                     /gene="Rabl3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggaaatcgt ggcaagatgg cgtccctgga tcgagtgaag gttctggtgt tgggagactc
       61 aggtgttggg aaatcttcac tcgtccatct tctgtgccac aatcaagtgt taggaaatcc
      121 atcatggact gtgggatgct cagtggatat cagagttcat gactacaaag aagggacccc
      181 tgaagagaag acctactata tagaactatg ggatgttgga ggctctgtgg gcagtgccag
      241 cagtgtgaaa agcacaagag cggtgttcta caactctgta aatggcatca ttttagtaca
      301 tgacttaacc aataagaagt catctcaaaa cttataccgc tggtccttgg aagttctcaa
      361 tagggatgca gttccaaccg gagtcctggt gacaaatggg gattatgacc gagaacagtt
      421 tgctgataat caaatcccac tgttggtgat agggactaaa ctggaccaga ttcatgaaac
      481 caagcgccat gaggttttaa tcaggaccgc cttcttggct gaggacttca atgctgaaga
      541 gattaatttg gattgcacaa acccacggtc ctcagctgca ggctcctcca acgctgtcaa
      601 gctcagtaga ttttttgata aggtcataga aaagagatat ttgtttagag aaggtaatca
      661 gattccgggc ttttccgata ggaagaggtt tggaggaggg acactgaaga acttccactg
      721 tgactgagtt gccctcagcc ctggaagagg aagggaacaa cagcagggtc cacagcttcc
      781 tcttgctgtg tcgggtcatt aacttctcag gcttcggtaa aaacatctca aaatgctacc
      841 tcaccctctc atggaagatt ggaaggaagc agcgacatgg aatgccctcg ctctgcccgt
      901 tctctgtact cctcaccacc ctgtctctgt ttatagctta tgtaaaagcc tatgaggtct
      961 tgtcaaaccc atgcagtaaa ggactggaga caagggctgc agagaaggct gactcctgct
     1021 tggaaccaga gggttttaca ggcctgcgat ttccccatac ttactgctga aggcttaatt
     1081 aagtacttca gaaacatatc tgtgttgttt taccttcctg aggggaaagg tcatgttaat
     1141 cagccctgag ttatctaccc caaccatctc tgtcacgtta aaagaagcca aatggtgtta
     1201 tttcattttc tctgtcctca ttccccacag ggatgcctaa gaatagcaac cccatctcct
     1261 ctgcgctctc tgggaaaagg cttagtgtct gggagagagc aatgaactaa tagctggagt
     1321 taaatagaaa tacaaattaa taatacatgg agagcagacc aggaaagaag ggtctgtgag
     1381 acaccgacag ctccccctct ctatagactg tcggaaggcg ctttctgctt tctgtttgga
     1441 aattggacga agtctgagac acgcacaagg ccagtaaaac agatttatgc ctctttggtg
     1501 gggttttctt tttttttttt tttttttttt ccttttctca gtttggttgg ttgttgtcct
     1561 atttatttgt aaagaaattc agttcctgaa atgtccctta gtctgatgaa cagtaaacta
     1621 ataatattgt ccttatgcta acaatgtatt tatgagaaag tcaactaggt tccagagtga
     1681 cacatttaca tacattatga gccgggttcg agagttcaca gtcacaccac agcttttgct
     1741 ggtggtgtgt atgtgtctgc ataattgttc atcattgttt cttagtctct cctttttgct
     1801 gggttaatct ttcggcccaa ttccttagtt tataaaattg gttgccaaaa acggctgtaa
     1861 ctggctgctg tgttcaacac cttgttatcc agatgctctg tctctacagt ggctctctac
     1921 tccctggttt tataccagat taaaaaaata atagtatgaa t
//
