LOCUS       NM_001013221            1830 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus RAB, member of RAS oncogene family like 2
            (Rabl2), mRNA.
ACCESSION   NM_001013221 XM_343315
VERSION     NM_001013221.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1830)
  AUTHORS   Kanie T, Abbott KL, Mooney NA, Plowey ED, Demeter J and Jackson PK.
  TITLE     The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate
            Intraflagellar Transport at the Ciliary Base
  JOURNAL   Dev Cell 42 (1), 22-36 (2017)
   PUBMED   28625565
REFERENCE   2  (bases 1 to 1830)
  AUTHORS   Nishijima Y, Hagiya Y, Kubo T, Takei R, Katoh Y and Nakayama K.
  TITLE     RABL2 interacts with the intraflagellar transport-B complex and
            CEP19 and participates in ciliary assembly
  JOURNAL   Mol Biol Cell 28 (12), 1652-1666 (2017)
   PUBMED   28428259
REFERENCE   3  (bases 1 to 1830)
  AUTHORS   Lo JC, Jamsai D, O'Connor AE, Borg C, Clark BJ, Whisstock JC, Field
            MC, Adams V, Ishikawa T, Aitken RJ, Whittle B, Goodnow CC, Ormandy
            CJ and O'Bryan MK.
  TITLE     RAB-like 2 has an essential role in male fertility, sperm
            intra-flagellar transport, and tail assembly
  JOURNAL   PLoS Genet 8 (10), e1002969 (2012)
   PUBMED   23055941
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC083624.1.
            
            On Apr 20, 2005 this sequence version replaced XM_343315.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083624.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1830
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..1830
                     /gene="Rabl2"
                     /gene_synonym="Rabl2a; Rabl2b"
                     /note="RAB, member of RAS oncogene family like 2"
                     /db_xref="GeneID:362987"
                     /db_xref="RGD:1306749"
     exon            1..292
                     /gene="Rabl2"
                     /gene_synonym="Rabl2a; Rabl2b"
                     /inference="alignment:Splign:2.1.0"
     exon            293..446
                     /gene="Rabl2"
                     /gene_synonym="Rabl2a; Rabl2b"
                     /inference="alignment:Splign:2.1.0"
     CDS             340..1008
                     /gene="Rabl2"
                     /gene_synonym="Rabl2a; Rabl2b"
                     /note="rab-like protein 2A; RAB, member of RAS oncogene
                     family-like 2B; RAB, member of RAS oncogene family-like
                     2A"
                     /codon_start=1
                     /product="rab-like protein 2B"
                     /protein_id="NP_001013239.1"
                     /db_xref="GeneID:362987"
                     /db_xref="RGD:1306749"
                     /translation="MAGDRSKQGELDQEKYDAHENVKIICLGDSAVGKSKLMERFLMD
                     GFQPQQLSTYALTLYKHTATVDGKTILVDFWDTAGQERFQSMHASYYHKAHACIMVFD
                     VQRKITYKNLGTWYAELREFRPEIPCILVANKIDDIQMTQKNFSFAKKFSLPLYFVSA
                     ADGTNVVKLFNDAIRLAVAYKKSSQDFMDEVLQELENFKLEQKEEDTPDQEQGDMSKS
                     PSPS"
     exon            447..476
                     /gene="Rabl2"
                     /gene_synonym="Rabl2a; Rabl2b"
                     /inference="alignment:Splign:2.1.0"
     exon            477..556
                     /gene="Rabl2"
                     /gene_synonym="Rabl2a; Rabl2b"
                     /inference="alignment:Splign:2.1.0"
     exon            557..636
                     /gene="Rabl2"
                     /gene_synonym="Rabl2a; Rabl2b"
                     /inference="alignment:Splign:2.1.0"
     exon            637..748
                     /gene="Rabl2"
                     /gene_synonym="Rabl2a; Rabl2b"
                     /inference="alignment:Splign:2.1.0"
     exon            749..843
                     /gene="Rabl2"
                     /gene_synonym="Rabl2a; Rabl2b"
                     /inference="alignment:Splign:2.1.0"
     exon            844..927
                     /gene="Rabl2"
                     /gene_synonym="Rabl2a; Rabl2b"
                     /inference="alignment:Splign:2.1.0"
     exon            928..1804
                     /gene="Rabl2"
                     /gene_synonym="Rabl2a; Rabl2b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtaagcggta agccggctgc ctttgaggtc caggggctgt ggtgggaaag cgcatctgcg
       61 gtgtcccgag tccctctgag ccttcgcgaa gccgaactga ggacaaagta cctgggaaca
      121 cccgcccgag agatgggacg gagggaaggc agaggcccag ccgagacccg acccagatcg
      181 cgggtccttt acgggagatg gtggctaggc ccgatgagcg cctaaaaacg tttgtcacac
      241 gaaagagagc ttgaccgcat gaagacagtg acagtcactg agggattcca ctacggtgac
      301 aagactccaa ggctgacact tgtccacgga cacgagctaa tggcagggga cagaagcaag
      361 cagggtgagc tggaccaaga gaagtacgat gctcatgaaa acgtgaagat catctgcctg
      421 ggggacagtg cagtgggcaa gtccaaactc atggagaggt ttctcatgga tggattccag
      481 ccacagcaac tgtccacata tgctctgacc ctgtataaac acacggccac agtagacggc
      541 aagaccatcc ttgtggactt ctgggataca gcaggccagg agcggttcca gagcatgcat
      601 gcctcctact accacaaggc tcacgcctgc atcatggtat ttgatgtcca gaggaaaatc
      661 acctataaga acctgggcac ctggtatgca gaacttcggg agttcaggcc ggagatcccg
      721 tgcatcctgg tggccaataa aattgatgac atacagatga ctcaaaagaa tttcagtttt
      781 gccaagaagt tctccctacc cctgtacttt gtctcggctg ctgatggaac caatgttgtg
      841 aagctcttca atgatgctat tcggttagct gtggcttaca aaaaaagttc ccaggacttc
      901 atggatgagg ttttacagga gcttgagaac ttcaagttgg agcagaaaga agaggataca
      961 ccagaccaag agcagggtga catgagcaag agcccatctc cttcttaacc agaggacatc
     1021 cacacatggc agaattgggg tattggggac catttggaac accctacatt gctggagaac
     1081 ctctctagac tacccctgct caacttcctg caaacccact gttctgtggt acttgatgag
     1141 gtcaacacaa actagacaga tgtgataccc accagcttcc tgcatcagga tgagggatcc
     1201 gtgtctttca catcccccac ccccacccca gcagcctgac agtgcagaaa cagtgcacat
     1261 gctcatgtct tcttagtaga catttaggtg tttgttggtc tttcttccca aactgacctc
     1321 agggactgtc acttcctttt tgccgagaga atgatgcaaa aggactgtgt ccctacagaa
     1381 tccatccatg atacccctgt ccctgtctcc caaccaactt tctcaacaat attttgacag
     1441 acaactgtta attccagatt tgtttttagc accgactgtt tcaggagctc ttctaggtca
     1501 gttgagagca caggagcaga actattgcgg tggagtgaag acaagtctag ccatatctgc
     1561 ttacacacac tttactgttc cccaccacat gaacaaaaac cccctttaaa cctccatctc
     1621 agggtagaaa gcttcctcca cctctggggc gagccacaca ctgcgtcgtg gtcagggtag
     1681 cagtgaggag cagaggagag ccgcctgcgc tctgcagctt gctggattgc cttgtctcga
     1741 gcatttgcat tatcattttg tttatattgt ttcctttttt acaataaaga gtacgtttca
     1801 taaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
