LOCUS       XM_039089587            4418 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus RAB guanine nucleotide exchange factor
            1 (Rabgef1), transcript variant X1, mRNA.
ACCESSION   XM_039089587
VERSION     XM_039089587.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051347.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039089587.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4418
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4418
                     /gene="Rabgef1"
                     /note="RAB guanine nucleotide exchange factor 1; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 19 ESTs, 1 long SRA read, 8 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 37 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:360797"
                     /db_xref="RGD:1307295"
     CDS             767..2317
                     /gene="Rabgef1"
                     /codon_start=1
                     /product="rab5 GDP/GTP exchange factor isoform X1"
                     /protein_id="XP_038945515.1"
                     /db_xref="GeneID:360797"
                     /db_xref="RGD:1307295"
                     /translation="MGGGDAHPLSQNTGREPAWSIEKKMSLKSERRGIHVDQSELLCK
                     KGCGYYGNPAWQGFCSKCWREEYHKARQRQIQEDWELAERLQREEEEAFASSQSSQGA
                     QSLTFSKFEEKKTNEKTRKVTTVKKFFSASSRAGSKKAEIQEAKAPSPSINRQTSIET
                     DRVTKEFIDFLKTFHKTGQEVYKQTKMFLEAMPYKRDLSIEEQSECTQDFYQNVAERL
                     QTRGKVPPEKVEKMMDQIEKHIMTRLYKFVFCPETTDDEKKDLAIQKRIRALHWVTPQ
                     MLCVPVNEEIPEVSDMVVKAITDIIEMDSKRVPRDKLACITRCSKHIFNAIKITKNEP
                     ASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLCCAVAFIE
                     KLDAQSLNLSQEDFDRYMSGQTSPRKQESESWSPEACLGVKQMYKNLDLLSQLNERQE
                     RIMTEAKKLEKDLIDWTDGIAKEVQDIVEKYPLEIKPPNQPLAAIDSENVENDKLPPP
                     LQPQVYAG"
ORIGIN      
        1 atacttctac ctggtgctag aggccaaggt tatggggtgt ctctgaatga gaagtcctga
       61 agctgaggca ggaggattgc cgcgagtatg agatcattct ctgtcactta ggaagaccct
      121 tttatgggaa aaaataataa aggcagcccc tgataccgag ctgtcttgaa ggagagccgc
      181 gggatgtccc tccatccctt cgcggaagtt tgctccatag agggaagcgc cttagagact
      241 aggtcattgg cagctggctg tgtctcagag ctgatgacca acctttgtgg ttgggaaatg
      301 tgttgctgga tgtggtaggc tccgtctgcc cgtggagttt agatgtgaca ctttggcaga
      361 agtttacagc atcatctagt tttgtggttg tccctgttgt ccccccaccc ccttccacct
      421 cctagaagtt aacagttggg cttttttttt ttttttcttt ttttcggagc tggggaccga
      481 acccagggcc ttgcgcttgc taggcaagcg ctctaccact gagctaaatc cccaacccct
      541 cagttgggcc ttttaaccta caaacctaga attactttaa aagcaagacc taattagtca
      601 cccacctctg gcatcccagt agttggaaat tgaggcagga acagagcttg acatcaacag
      661 ggatatacta cagagtaaaa ttagacaccc ccacccccag cccccaatcc tccaaagtcg
      721 cagttaaaag aagagtctca aaattgtctt gtcaagaagc ttgttaatgg gcggcggtga
      781 tgcacaccct ttatcccaga acacaggaag agaaccagcc tggtctatag agaagaagat
      841 gagcctgaag tccgaacgcc ggggaattca tgtggatcag tcggagctcc tgtgcaagaa
      901 aggatgtggt tattatggaa accctgcctg gcagggtttc tgctccaaat gctggaggga
      961 ggagtaccac aaggcccggc agaggcagat ccaagaggac tgggaactag cagaacgact
     1021 tcagcgggag gaggaagagg ccttcgctag cagccagagc agccaaggag cccagtccct
     1081 caccttctcc aagtttgagg agaagaaaac caatgagaaa actcgcaaag tcaccacagt
     1141 gaagaagttc ttcagcgcct cttccagggc tggatccaag aaggcagaaa ttcaggaagc
     1201 caaagctccc agtccctcca taaaccggca gaccagcatt gagacggacc gagtgactaa
     1261 ggagttcata gactttctca agaccttcca caagacaggc caagaagtct ataaacagac
     1321 gaagatgttt ttggaagcaa tgccttataa aagggattta agcatcgagg aacagtcaga
     1381 atgtactcag gacttttacc agaatgtggc ggaaaggttg cagacccgcg ggaaagtgcc
     1441 tccagagaaa gtggagaaga tgatggatca gatcgaaaag cacatcatga cccgtctcta
     1501 taaatttgtg ttctgcccag agacgactga tgacgagaaa aaagatctcg ccattcaaaa
     1561 gaggatcagg gctctgcact gggtgacacc tcagatgctc tgtgtcccgg tcaatgagga
     1621 aatcccggaa gtgtctgaca tggtggtgaa agcgatcaca gacatcattg agatggactc
     1681 aaagcgtgtg cctcgggaca agctggcctg catcaccagg tgtagcaagc acatcttcaa
     1741 tgccatcaag atcaccaaga atgagccagc ctctgccgat gacttcctgc ccacccttat
     1801 ctacatcgtc ctgaagggca acccccctcg tctgcagtcc aacatccagt acatcactcg
     1861 cttctgcaac cccagccggc tcatgacggg cgaggatggc tactacttca ccaacctgtg
     1921 ctgtgctgtg gctttcattg agaaactaga cgctcagtct ttgaatttaa gtcaggagga
     1981 ttttgaccgg tacatgtctg gccagacgtc ccccaggaag caagagtctg agagttggtc
     2041 cccggaggcc tgcttaggtg tgaagcaaat gtataagaac ttggacctcc tgtctcagct
     2101 gaatgaacgg caggaaagaa tcatgactga agccaagaaa ctcgaaaaag acttaataga
     2161 ctggacagat gggatcgcca aggaagttca agacattgtt gagaagtacc ctcttgagat
     2221 taagccccca aaccaaccct tagcagccat tgactctgag aatgtggaga acgacaagct
     2281 ccctccccct ctgcagccgc aggtgtatgc agggtgatgt ctcgctcacg gccggcttga
     2341 tttggggctg atttcaggga gctgctgcgt tccactgttt gggtctggag tatgaattaa
     2401 ctgcttacaa tttcaaagta tttttaaggt acagatttag ggattgttta ttttcttttt
     2461 tttttcctag caggggaagc ttagtaaata ataatgtcct atttatttga gttggtgaag
     2521 taggtttgtg tgaattctgt gtcaatcttt tatgtccttt ctgattctcc cacgggcttc
     2581 ctctgtggta gacactgttg ttggttttgg gcaaacactg tcttttaaag gataaaacag
     2641 atgctataaa gtctatgttg aaatgaattc tatgttccca cactctccca gtgtgaaata
     2701 attttgtaat tgtaaagata gaagataatg ttaataagta aatatgtaaa attgtaaata
     2761 tgtaaaaaaa aatagggctg ggaggggtgg tatcagcgtg catggcattt catgagctga
     2821 tttttttttt taggtgaaaa tgaaatatat tgaatgtttg cctttagcac cattttattt
     2881 ggtttgtttg tcccactaaa aataatctaa aaatacatga gctttaacag gacactagca
     2941 ctaactgccc taactctgag gtcctggtac atgttaatga agttgtgaca ccaactttta
     3001 ggtcacataa agaattgttc tgggaccctg gggtggtagc tcaggcagta aagtgctttc
     3061 cacactggtt caaggacctg agcttcctgt ccagcccccc atgtgaaaag ccagacatgg
     3121 tgacgcacag ttggaacagt gctgctggaa ggcacagatg ggcaggttcc tgggggaatg
     3181 tcctcctgac cctgattaaa caaaggaacc aagatggaca gctcctgaga aatgatagcc
     3241 aaggttgacc tctggcttcc acatgcctac atctgtgcct gtgtacctct acacacatgt
     3301 gtaccacata cacatgaaca cactgttgct aattagtacg gttgactttg aactgtgctc
     3361 atagcttcct ttccctaatt catccaataa acttccccca caatgttatg ggggctattg
     3421 cctttttgaa ttgattggtt ctgttttgtt ccttggtctt ttgggacagg ctgttgctat
     3481 gtaacccagg ctgtcctcaa acttgtgatc ctccaacctc agcctcccga cgtcgggatt
     3541 ggtgggtttg taccatcaca tttagctcat gcagacaaag catcaccgag ttccgtgata
     3601 caacgatgtg gtcgtggatg caagttggag cgaatgaatg aggctaatgg gagttgacag
     3661 ggaacttctc aaagcgcgga gcaagtgggt gccttgcgcc cttcatagtt tgctttacct
     3721 ttatcaacag gtaacagaca gcaggtcaca tagacatctc agaacttcta acctctgaat
     3781 tgacaattgt ggcctaaggt tttgttgtta tggcaacact gccttgtaca ttgtggggta
     3841 ttgagtaggg tttctgcttt ctgtaccagt agatgccggc agcccgcccc ccatgtgtta
     3901 tcatgtgata aggacttatc aggagttcag atcatcctca tacacatagt gagtttgaag
     3961 aaagcctgga ctatagaact ccttgtctca aaaagagaaa gactaaagaa acctgtctct
     4021 atctggtgtc tcctggggga cagaattagc ctgtactaaa aatcaccggt ctcttgtcag
     4081 ccagtgggtt atgcacctgg tatagttaat aagctagaac caaagattat atagtgtaat
     4141 attacttgat gtctccctct gtgaggccct gcctcgcggg actcttctct aatccctgtg
     4201 gaatttttat aaccaggtta taccccagat ggatgactct tctgcatggt tatcagcacc
     4261 tttgtgaaat tagttgttcc tcaggacgcc attcttcaac agtgtcatag cattcaagga
     4321 gctgagaaag gctttcttcc tttctcaaca tattttccta aatgtttact acacatatgc
     4381 agcataagaa tttttggaat aaaagtagga caaaaata
//
