LOCUS       NM_001107841            5015 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus RAB GTPase activating protein 1 (Rabgap1), mRNA.
ACCESSION   NM_001107841 XM_001054010 XM_231251
VERSION     NM_001107841.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5015)
  AUTHORS   Yoshimura S, Egerer J, Fuchs E, Haas AK and Barr FA.
  TITLE     Functional dissection of Rab GTPases involved in primary cilium
            formation
  JOURNAL   J Cell Biol 178 (3), 363-369 (2007)
   PUBMED   17646400
REFERENCE   2  (bases 1 to 5015)
  AUTHORS   Fuchs E, Haas AK, Spooner RA, Yoshimura S, Lord JM and Barr FA.
  TITLE     Specific Rab GTPase-activating proteins define the Shiga toxin and
            epidermal growth factor uptake pathways
  JOURNAL   J Cell Biol 177 (6), 1133-1143 (2007)
   PUBMED   17562788
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473983.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001054010.1, XM_231251.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132291,
                              SAMD00132292 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..5015
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q11"
     gene            1..5015
                     /gene="Rabgap1"
                     /note="RAB GTPase activating protein 1"
                     /db_xref="GeneID:311911"
                     /db_xref="RGD:1304691"
     exon            1..187
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            188..386
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     CDS             237..3434
                     /gene="Rabgap1"
                     /codon_start=1
                     /product="rab GTPase-activating protein 1"
                     /protein_id="NP_001101311.1"
                     /db_xref="GeneID:311911"
                     /db_xref="RGD:1304691"
                     /translation="MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDD
                     EKTGLKIVGNGSEQQLQKELADVLMDPPMDDQPGMERSHLDGEGDGPLSNQLSASSTI
                     NPVPLVGLQKPEMSLPVKSGQGDSEVSSPFTPVADEDSVVFNKLTYLGCASVNAPRSE
                     VEALRMMSILRSQCQISLDVTLSVPNVSEGTVRLLDPQINTEIANYPIYKILFCVRGH
                     DGTPESDCFAFTESHYNAELFRIHVFRCEIQEAVSRILYSFATAFRRSAKQTPLSATA
                     APQTPDSDIFTFSVSLEIKEDDGKGYFSAVPKDKDRQCFKLRQGIDKKIVICVQQTAN
                     KELAIERCFGLLLSPGKDVRNSDMHLLDLESMGKSSDGKSYVITGSWNPKSPHFQVVN
                     EETPKDKVLFMTTAVDLVITEVQEPVRFLLETKVRVCSPNERLFWPFSKRSTTENFFL
                     KLKQIKQKEKKNNADTLYEVVCLESESERERRKTTASPSVRLPQSGSQSSMIPSPPED
                     DEEEDNDEPLLSGFGDVSKECAEKILETWGELLSKWHLNLNVRPKQLSSLVRSGVPEA
                     LRGEVWQLLAGCHNNDHLVEKYRILITKESPQDSAITRDINRTFPAHDYFKDTGGDGQ
                     DSLYKICKAYSVYDEEIGYCQGQSFLAAVLLLHMPEEQAFSVLVKIMFDYGLRELFKQ
                     NFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEAHMYASQWFLTLFTAKFPLYMVFHI
                     IDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFFRVQLPKRYRSEENAKRLME
                     LACNTKISQKKLKKFEKEYHTMREQQAQQEDPIERFERENRRLQEANMRLEQENDDLA
                     HELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEDEKRRLEEESAQLKEMCRR
                     ELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIEKIRQKVDDCDRCRDFF
                     NKEGRVKGASSVKGVSDEDTDEEKETLKNQLRELELELAQTKLQLVEAECKIQDLEHH
                     LGLALSEVQAAKKTWFNRTLSSIKTATGVQGKETC"
     exon            387..609
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            610..814
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            815..989
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            990..1147
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            1148..1258
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            1259..1325
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            1326..1428
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            1429..1598
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            1599..1773
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            1774..1867
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            1868..2018
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            2019..2132
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            2133..2207
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            2208..2333
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            2334..2477
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            2478..2519
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            2520..2648
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            2649..2741
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            2742..2852
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            2853..2957
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            2958..3041
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            3042..3113
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            3114..3311
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
     exon            3312..5015
                     /gene="Rabgap1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 attgtgggcg gggcgcgggg cgaggttggg gaatccggcc gcggagagtc ggctctgtga
       61 gctccgcagt tgcggctctt ctgtagcagg tgggccagag ctctgttctt cgcggctgca
      121 gtcacgaagg gctcccgccg gccgttgtct gcatgggcct gagcagcctg tctgcgagca
      181 agccgtggca tttaaaaaat tttaaccatt catgagttga gcctcattct tgagttatgg
      241 atgacaaggc ctctgttgga aaaatcagtg tctcttcaga ctcagtgtcc actcttaata
      301 gtgaagattt tgtcttggtt tccaggcaag gagatgagac accatctaca aataatggga
      361 gtgatgatga gaagacggga ctcaagattg tagggaatgg gagtgaacag cagcttcaga
      421 aagagctagc agatgtgctg atggatcctc ccatggacga ccagccaggg atggaaaggt
      481 cacacctgga tggggaagga gatgggcctc tttctaatca gctctcagct tcatccacca
      541 ttaatcctgt gcccctggta gggcttcaga aaccagagat gagcctgcca gtgaaatctg
      601 gacaaggaga ttctgaagtg tcaagtcctt tcacaccagt ggctgatgag gatagtgtag
      661 ttttcaataa actaacttac ttaggctgtg cctcagtaaa tgctccccgg agtgaagtgg
      721 aagccttgag gatgatgtct atcttgagaa gtcagtgtca gatttctctg gatgtaaccc
      781 tctcagtgcc gaatgtatct gaaggaactg tgagactttt agatcctcaa ataaacactg
      841 aaatagcaaa ctaccctatc tacaaaatcc tcttctgtgt tagagggcat gatgggactc
      901 ctgaaagtga ctgttttgca ttcactgaaa gtcactacaa cgcagagctc ttcaggatac
      961 atgtctttcg ctgtgaaata caagaagctg taagccggat actttacagt tttgccaccg
     1021 ccttccgccg ctctgccaag cagaccccac tctcagccac agctgcacca cagactcctg
     1081 acagcgacat ctttaccttc tctgtgtctt tagaaataaa agaagatgat ggtaaaggtt
     1141 attttagtgc tgttcccaaa gacaaggaca gacagtgctt taaactgcgc cagggtatcg
     1201 ataagaagat tgtcatctgt gtgcagcaaa cagctaacaa agaacttgcc attgaaaggt
     1261 gcttcggtct tctccttagc ccaggaaaag atgtccgaaa tagtgatatg cacttgttgg
     1321 atttggagtc tatgggcaaa agttcagatg gaaagtcata tgttattact ggaagctgga
     1381 atccgaagtc cccacatttt caagttgtga atgaagaaac tcctaaagat aaagtgctgt
     1441 tcatgacaac agctgtggat ttggtgataa cagaagtaca ggaacctgtt cgatttcttc
     1501 tagagacaaa agttcgagta tgctcaccta atgaaaggtt attctggccc ttcagcaaac
     1561 ggagcactac tgagaacttc tttctgaaac tgaagcagat aaagcagaag gagaagaaga
     1621 ataatgctga cactttatat gaagttgtgt gtttggaaag tgagtcagag agagagagga
     1681 ggaaaactac agccagtcct tcagttcgcc tgccacagtc tggatcccag agctccatga
     1741 tcccctctcc tccagaagac gatgaagaag aggataatga tgagcctctg ttgagtggat
     1801 ttggggatgt atccaaagaa tgtgcagaaa aaattcttga aacatgggga gaactgctgt
     1861 caaaatggca tctcaacttg aatgtgagac caaagcagtt gtcatcctta gtgagaagtg
     1921 gtgttcctga agctctccgt ggagaagtct ggcagctgct agcaggctgc cacaacaacg
     1981 atcacttagt ggaaaagtac cggattctca tcacaaagga gtctccccaa gacagtgcta
     2041 tcaccagaga tattaaccgc acatttccag ctcatgacta cttcaaggac acaggaggag
     2101 atggacaaga ttccttatat aaaatatgca aggcatattc tgtgtatgat gaagagattg
     2161 gttattgcca gggccagtcc ttcctcgcgg ctgtgctgct tctccacatg cctgaagaac
     2221 aggcattcag tgttctggtc aagatcatgt ttgactatgg tctcagggaa cttttcaagc
     2281 aaaattttga agatctacat tgcaagttct accagctgga gcgcctcatg caggaatata
     2341 ttcctgatct gtacaaccac ttcctggata tcagccttga agcacacatg tatgcctccc
     2401 agtggttcct tacactgttc actgcaaaat tccctctcta catggtcttc catatcatcg
     2461 acctgctctt atgtgaggga ataagtgtca tctttaatgt tgcccttgga ttactaaaga
     2521 cttccaagga tgacttgctg ttgacagact ttgagggtgc cttgaagttc ttcagggttc
     2581 agctccctaa aagataccgc tcagaagaaa acgcaaagag gctcatggag ctagcctgca
     2641 acacaaagat tagccaaaag aagctgaaga agtttgaaaa agagtaccat accatgcggg
     2701 agcagcaggc ccaacaggaa gatcccatcg agcggtttga gcgggaaaat aggcggctac
     2761 aagaagccaa catgaggctg gaacaggaaa acgacgactt agcccatgag ctggtcacca
     2821 gtaaaatcgc actgcggaag gacctggata atgcagagga aaaggcagat gcattgaata
     2881 aggagctgct aatgaccaag cagaagctga ttgatgcaga agatgagaag agaaggttag
     2941 aagaggagtc tgcacagtta aaggaaatgt gccgccgtga acttgacaag gcagaatcag
     3001 agattaaaaa aaacagctct atcattggtg actataagca gatttgttct caactgagtg
     3061 aaagactgga aaagcaacag acagccaata aagtggaaat tgagaaaatc cggcaaaagg
     3121 tagatgactg tgaccgctgc cgagacttct tcaacaaaga agggcgagtg aaaggtgcca
     3181 gctcagtcaa gggggtttca gatgaggaca cagacgaaga aaaagaaaca ctcaagaacc
     3241 agctgcggga gctggagctg gagctggcac aaaccaaact gcagctggta gaagctgagt
     3301 gcaagatcca ggacttggaa caccacttgg gccttgccct cagtgaggtg caggctgcca
     3361 agaagacctg gtttaaccga acactgagct ccataaagac agcaacgggc gtgcaaggga
     3421 aagagacgtg ctgagagcag ctgctgcttc cacacacctc agaaaacaca ccaccttttg
     3481 ttgccttctt tggccagatg tgtgattctg tgatatgttg caggaccaga atgtactagg
     3541 tcagagctgt atagtatgtt ggtaggtcag tgggccaggg ctcctgcagc aggctgccaa
     3601 cccaactgac gctttgggca tgcaccagag tccttcctcc tagtgccatt caggcctctt
     3661 ttctgtatag gaacacttca cacagccaga gttagggtat cccccaatgt attgggtttt
     3721 ctttttaaac cctttaaaaa aaattgtgtg tgtgtgtgtg tatgtgtgta catatacaca
     3781 tgcagacact ctgccctttt gagtggggag cagggattca gagattagag taattctcat
     3841 ctgtcattgc cagcaaaagc tcccagagac atgaaaagca ctttgagtaa agggtctcgt
     3901 agtcacaggt caagtcactt aattttgtta actaatatag tgcataggtt ttgatttgga
     3961 attattcaca ttgccgagca attctatgca actctcatag tcttattccc ttcctccctt
     4021 ccttccttcc ttccttcctt ccttccttcc ttccttccaa aaaagcatta gctgccaaaa
     4081 ctacttctat aggctggaat gggccacatg actgtgagac tgaatcaatc atgacatgga
     4141 cagctctttg ttaaagtgtc atgtgtgtat atatgtgtgt gtctgtctgt ctgtctgtct
     4201 gtatatatgt gtgtgtgtat ataaatatat aaatatatat atatatatat aaataccttt
     4261 cccggcaccc tgcagtgaca gtgtttaagt cccagacaac ctgctaatct accactgcca
     4321 tctgtggtta tggggcactt cctttcactc aaggtttatt gggctctggt ctttaagagc
     4381 tccttgacca ctaatgtttt gcatagcagg ttgttcaagt aaggaagact gaatacatga
     4441 aagtatgtac acactgtaag atcttacttt cctggctcaa tctttgtcag gcctctgaag
     4501 cctcccagag tagccaggta tcgatctcac tggtcaggtg atgggctgtg gattctcacc
     4561 ttaaagctat gaaatggtgg ttttagcacc tttttaaaat ttaaaaaaaa aaaaaaaacc
     4621 ttttgactct taatttatat gctgacaagc agtctcacaa gtggctcatc ttctctgctg
     4681 tatggtctgc tctgtgtgga ggtagcttgg gtttgtatat aaggacacga gttatttcct
     4741 cttcccctgt tggctttact aatgcttgat gaggtcatct acagtgggga gataataagt
     4801 ggcctgctct tccccagacc atcccctacc acttccagta tctgtcctat tcagttaacc
     4861 caaatagctg taagcccatc taaaactagg tgtgtggaca ttatgtgcta gggtagtttg
     4921 tgcgtcaact ttatgaactg aaatataaac cagtaaaatt gtattactat ttcttttgtt
     4981 ttaacagcat attcattaaa tattttggta caaac
//
