LOCUS       NM_001108775            5002 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus RAB6B, member RAS oncogene family (Rab6b), mRNA.
ACCESSION   NM_001108775 XM_001072138 XM_006243669 XM_343459
VERSION     NM_001108775.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5002)
  AUTHORS   Lindsay AJ, Jollivet F, Horgan CP, Khan AR, Raposo G, McCaffrey MW
            and Goud B.
  TITLE     Identification and characterization of multiple novel Rab-myosin Va
            interactions
  JOURNAL   Mol Biol Cell 24 (21), 3420-3434 (2013)
   PUBMED   24006491
REFERENCE   2  (bases 1 to 5002)
  AUTHORS   Pavlos NJ, Gronborg M, Riedel D, Chua JJ, Boyken J, Kloepper TH,
            Urlaub H, Rizzoli SO and Jahn R.
  TITLE     Quantitative analysis of synaptic vesicle Rabs uncovers distinct
            yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered
            exocytosis
  JOURNAL   J Neurosci 30 (40), 13441-13453 (2010)
   PUBMED   20926670
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000200.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001108775.3.
            
            On or before Feb 4, 2022 this sequence version replaced
            XM_006243669.4, NM_001108775.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB577150.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-416               JACYVU010000200.1  6654111-6654526
            417-475             JACYVU010000200.1  6681767-6681825
            476-529             JACYVU010000200.1  6699617-6699670
            530-635             JACYVU010000200.1  6699862-6699967
            636-747             JACYVU010000200.1  6701257-6701368
            748-841             JACYVU010000200.1  6702612-6702705
            842-908             JACYVU010000200.1  6705820-6705886
            909-5002            JACYVU010000200.1  6718713-6722806
FEATURES             Location/Qualifiers
     source          1..5002
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..5002
                     /gene="Rab6b"
                     /note="RAB6B, member RAS oncogene family"
                     /db_xref="GeneID:363123"
                     /db_xref="RGD:1309958"
     exon            1..416
                     /gene="Rab6b"
                     /inference="alignment:Splign:2.1.0"
     CDS             347..973
                     /gene="Rab6b"
                     /EC_number="3.6.5.2"
                     /codon_start=1
                     /product="ras-related protein Rab-6B"
                     /protein_id="NP_001102245.2"
                     /db_xref="GeneID:363123"
                     /db_xref="RGD:1309958"
                     /translation="MSAGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQA
                     TIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNLNSFQ
                     QTSKWIDDVRTERGSDVIIMLVGNKTDLADKRQITIEEGEQRAKELSVMFIETSAKTG
                     YNVKQLFRRVASALPGMENVQEKSKEGMIDIKLDKPQEPPASEGGCSC"
     exon            417..475
                     /gene="Rab6b"
                     /inference="alignment:Splign:2.1.0"
     exon            476..529
                     /gene="Rab6b"
                     /inference="alignment:Splign:2.1.0"
     exon            530..635
                     /gene="Rab6b"
                     /inference="alignment:Splign:2.1.0"
     exon            636..747
                     /gene="Rab6b"
                     /inference="alignment:Splign:2.1.0"
     exon            748..841
                     /gene="Rab6b"
                     /inference="alignment:Splign:2.1.0"
     exon            842..908
                     /gene="Rab6b"
                     /inference="alignment:Splign:2.1.0"
     exon            909..5002
                     /gene="Rab6b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagagcgctc ctccgcccag ctcggtccct gcgccccgct ccgcccgtgc ctcgctgccc
       61 gcgccgagct tcgggcgtcc acagcgcgcc cttcgcccgt gcagccagcg ccacccaggg
      121 ctgcgccgcg caccccgcct cctccctttc cgccgtcgcc gccgtcggac acgcagccgc
      181 aggccggggc ccggccgcag ctggggagtc aggggcgcgc gcagccagcc cttccccctc
      241 cggctcccgc accgctcgcc gcctcccctc gccctcctcc tctcccctcc ctgctccttc
      301 gccgcttcct cctcctcctc ctcgcccggc cccagctgcc agcaccatgt ccgcaggggg
      361 agattttggg aacccgctgc gaaaattcaa gttggtgttc ctaggggagc agagcgtcgg
      421 gaagacgtct ctcatcacga ggttcatgta cgacagcttc gacaacacct accaggcaac
      481 catcgggatt gacttcttgt caaaaaccat gtacttggaa gaccgtacgg ttcgactgca
      541 gctctgggac accgctgggc aagagaggtt ccgcagcctg attcccagct acatccggga
      601 ctccacggtg gctgtggtgg tgtacgacat cactaatctc aactccttcc agcagacttc
      661 taaatggatt gatgacgtca ggacagagag gggcagtgac gtgatcatca tgcttgtggg
      721 caacaagacg gatctggctg acaagaggca gataaccatc gaggaagggg aacagcgggc
      781 caaagaactg agtgtcatgt tcatcgagac cagcgcgaag accggctaca acgtgaagca
      841 gctctttcga cgtgtggcat cagctctgcc cggcatggag aacgtccagg agaagagcaa
      901 agaagggatg attgacatca agctggacaa acctcaggag cccccggcca gcgagggcgg
      961 ctgttcctgc taatgcacag cccactcggc ttcctcaaca ccactcactt gttttgcctc
     1021 ctatcggtta gcttcctaac ggggtgggaa ctgagtttat caagacgggg aggatctttc
     1081 ttttctctct ctctctagga gtagggtggg acatggggag ggaggctggg cgtcagggac
     1141 cacgtcactc ttaaacagct gttacctaaa cgactatttt ttggtttggt tgtaatatat
     1201 tgtactttat taagattgcc aaaaactgtt aaaatttaaa aaaaaattta aatcatgtgt
     1261 atacaacttt ttgccagata agaaaagtag tcatttttat ttgaaagaag tgcttttttt
     1321 gtttgtttgt ttttgtatat ttgtaaactt acagagaacc tctctacaca ccccttcctt
     1381 cctgttctct tggaactgtg tgtcacctct attatcctcc tacccccagc ccagaaaatt
     1441 aaagcaatta actgaacagt agtaattacg ttctagttct gggtcacatg acccaagcca
     1501 accaagccca ggaccccaca gtcaaatcag actttaatct aacaaaacgg ccccagcagg
     1561 gccattattg agcccttcct tggcagagtg gggcacatta gcaggtccct gagtggaaat
     1621 gaaggccctt ggaccatagc ttcagcagca aacccctcgg ctgcttctgc ctcttctcct
     1681 tccctgaaaa gcaaacatgg agtcagagag cacaggcaac agtgtgttct ctgggctgac
     1741 ccagtgacga gcagaacaag aagttaccgg aaggatgggg tgctcttggc agctgtgggc
     1801 tgaggcagtg tgtggtctca aaggttgtaa tctactggcc ccacagctga cacatgtggt
     1861 taggctgact tgccaactcg ttatgtgatg ctgggtggct cagggatgct gacgcctagg
     1921 gcacatgcta tcactgcagc tgtgattgag gaagagaggg gtgtccgccg tgactctgaa
     1981 cgctccatgt tctcagaccc ttggttacca atcttgccga acgctgtcct ggaaaagttg
     2041 attcctcagt gtgttctcac ccctggcatg gtacgtttgc agtctttgta tgaatacctt
     2101 tggttgggag tgctgcggct gcacttcgag catcttggag tcactgtggg gtttccagaa
     2161 ggctgcccag ggcactgcca cctgcccccc cccccccagc aggctgtcct tgccgtctcc
     2221 actcattccc cagaccgttt ctgtcctgaa gaccttcaga gtctctaaca gagagtgctc
     2281 ttctcaaagc aaaataactc acattctaac tcactaccca tctgtctgcc tttgggcagg
     2341 cctagggcag tgactctaat cagaacatcc cagccccagt agcagtggtt cttcttccag
     2401 actgctggtg ggcaaagtga attgtctcca cagggcagaa ctacagcaag gaagttggca
     2461 tgaatgatgg aatctctcaa aaatgagttc aaaatggcag gctgattctg tgagtgggcc
     2521 tgtcatgccc ctccatcatg ggagacagtg tcagagccgg ttctggtgaa ggagaggaag
     2581 caggatcccc ctgggtacct cttccagaag gcaaggacca atgtatgagc atactgaagt
     2641 gtcacgtgtt tagtttttat atgtgtgtac ataactatac ttagagatag acttgtgtat
     2701 acaccctcca cacatcctca catacacatg tgctcactgt atatccacgt ctctcctgct
     2761 caccacttgg aacttgcatt gtgattccgg tttttggaaa aaagtatgca gtgtactgaa
     2821 ataagaaata attcaatatt gtcaaataac ttgtggttgt cttgccttca ataaaaatag
     2881 tgcatagatg tgttaaacta caagcaaaaa tagtccacag aattaccttc acactgcttt
     2941 atgtacctgt gtgcacaggt gtgcatgccg tcgtgggcca gtgtcccccc cagtgtggac
     3001 accccaccta tgtggtgctt gttggaagaa agcatactta ccccgtggtg acagcagcct
     3061 ggttggcagt gaggggcttt gctggtggcc tctggcagag ccccactgtc agaactctct
     3121 actggctctc actgaatgaa tgtagggtga attttaacct tcttgaccct gaataacctt
     3181 tcttgtattc ctgtaactcg gattagaagc tccattctct cgcttgtaca cacaatctaa
     3241 ggcgtcatgg tctgctgtta gaaacagcag gtgccatgtc agacactatt tctggttgat
     3301 ccagcctaag gaaccctgcc ttcctaacct gtgtacaaaa ttccttcttg agtttaggct
     3361 ctcccagccc tgcggcccct gaaaatgagg gttctgcccc atcactctcc catcccagag
     3421 gtaccctggc cttcttttcc tcagccaagc tacccatttc cttccctaaa ggcagttaaa
     3481 gcagccaggc cttaacacag aacagtattg gacctgggct ctccccttga ccatcaccac
     3541 catcatccta cttgtaggta ggatccagtc aggttctctt aaagacgtcc tgaaattatt
     3601 tgtccctgtt tttactaaat tcagatcagt cagaggacaa agtggaggat tcctcgtagg
     3661 gcatgatctc tggacaccgt gtctggcctg gcagatgggc atggccctct tccttttctt
     3721 taggagcctt gaaggacaat tgtcagtaaa acttctgtga gcagtgcaga aatagtctga
     3781 gattgaaaag gcaggtagca tagctgtaca cacctgcaga ccaaaacaaa ggtgtgacgt
     3841 cagtgtcctg agtgctggta ttgctgtggg gtcagaggct acagtgcttg gtggtgagag
     3901 ccttgctgtt atatcagtca ccgctccctg tcgacatctt tacacatttc ccagtatctc
     3961 aagatccagg aagccatggc cacatcagtt caatgtctca ggaaacaaaa ataagaattt
     4021 cgaaggggta gctaggagtg tagttgcctg ggcctagtct ctatcccagt ggctaaccaa
     4081 tgtcagatct aagcactgct ggcttcagca tcctgtgggc agagcagttt attcctcctc
     4141 catatggatg ggggagaggc tgtcagcaaa gactgggtag ctgaggatgg ggagttagcg
     4201 acacaagaac cagctagcaa gagtctgtct gagtgtcaaa ggctcagggc tcaatgccca
     4261 ctagtttcta aactacctct cccccaagaa tgggaggcac cgtgaccttg ccacagcact
     4321 gggagccaaa cccttcctgt tgcacaggtg ggagaaccgg aaaagacaag gtcaccccca
     4381 agccagagat gatcagaact agtgttggca ttcttgatga ggactgctgt gctcatgccc
     4441 ctaagccatc tctactgcgt ggcttacata aggatattcc cagcccgact agctagagag
     4501 aagataggtg catttcaggc tctcactgta aggaagggtg gtccccaaat ctacttgcat
     4561 tgtctgtgta cacacacaca cacacacact cacacacatg gagcagtagt cagggtaccc
     4621 ttttcatttt tgtttgaaat caacttcttc gctactccga aaacttgcag tttcaatgtg
     4681 cagacccctt ggactccaga ccccgtctga ttgacactct gcagtgcggt atgattatca
     4741 ggaaaacctt gcagcgggag tttggatggg cccttcagga ggcaggaagc ttccatagca
     4801 acgaaggcca gcctgcctgt tgtaatgtgt tgacttctca cctcacctgt ccttcaaagt
     4861 gaggagcaga gggcagcatc tccatctgta ctgggctcag aaggcacagt ggccatattg
     4921 actttacatt caactgtgta atatgtggaa aagactcagc atgttggtca aacaataaac
     4981 tgtcctaatt ctcgacacaa aa
//
