LOCUS       NM_017355               1130 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus RAB4B, member RAS oncogene family (Rab4b), mRNA.
ACCESSION   NM_017355
VERSION     NM_017355.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1130)
  AUTHORS   Pavlos,N.J., Gronborg,M., Riedel,D., Chua,J.J., Boyken,J.,
            Kloepper,T.H., Urlaub,H., Rizzoli,S.O. and Jahn,R.
  TITLE     Quantitative analysis of synaptic vesicle Rabs uncovers distinct
            yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered
            exocytosis
  JOURNAL   J Neurosci 30 (40), 13441-13453 (2010)
   PUBMED   20926670
REFERENCE   2  (bases 1 to 1130)
  AUTHORS   Kaddai,V., Gonzalez,T., Keslair,F., Gremeaux,T., Bonnafous,S.,
            Gugenheim,J., Tran,A., Gual,P., Le Marchand-Brustel,Y. and
            Cormont,M.
  TITLE     Rab4b is a small GTPase involved in the control of the glucose
            transporter GLUT4 localization in adipocyte
  JOURNAL   PLoS One 4 (4), e5257 (2009)
   PUBMED   19590752
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from X78605.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X78605.1, SRR8487227.257359.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1130
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..1130
                     /gene="Rab4b"
                     /note="RAB4B, member RAS oncogene family"
                     /db_xref="GeneID:50866"
                     /db_xref="RGD:620931"
     exon            1..91
                     /gene="Rab4b"
                     /inference="alignment:Splign:2.1.0"
     CDS             76..717
                     /gene="Rab4b"
                     /EC_number="3.6.5.2"
                     /note="ras-related GTP-binding protein 4b"
                     /codon_start=1
                     /product="ras-related protein Rab-4B"
                     /protein_id="NP_059051.1"
                     /db_xref="GeneID:50866"
                     /db_xref="RGD:620931"
                     /translation="MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVE
                     FGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAW
                     LTDARTLASPNIVVILCGNKKDLDPEREVTFLEASRFAQENELMFLETSALTGENVEE
                     AFLKCARTILNKIDSGELDPERMGSGIQYGDISLRQLRQPRSAQAVAPQPCGC"
     exon            92..172
                     /gene="Rab4b"
                     /inference="alignment:Splign:2.1.0"
     exon            173..287
                     /gene="Rab4b"
                     /inference="alignment:Splign:2.1.0"
     exon            288..350
                     /gene="Rab4b"
                     /inference="alignment:Splign:2.1.0"
     exon            351..505
                     /gene="Rab4b"
                     /inference="alignment:Splign:2.1.0"
     exon            506..601
                     /gene="Rab4b"
                     /inference="alignment:Splign:2.1.0"
     exon            602..732
                     /gene="Rab4b"
                     /inference="alignment:Splign:2.1.0"
     exon            733..1119
                     /gene="Rab4b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtggagcggc tgccagccgg ggaacaggcg cggccgcggc gccatattgc ggccctcagc
       61 ggtcgccacc gagccatggc tgagacctac gacttcctct tcaaattcct ggtgattggc
      121 agtgccggaa ctggcaaatc atgtctcctc catcagttta ttgagaataa gttcaaacag
      181 gactccaacc acactattgg cgtggagttt ggatccaggg ttgtcaacgt tggggggaag
      241 actgtgaagc tacagatttg ggatactgct ggccaggagc ggtttcggtc ggtgacacgg
      301 agttattacc gaggggcagc tggagccctg ctggtgtatg acatcaccag ccgggagaca
      361 tacaactcgc tagctgcttg gctgaccgat gcccggacgc tggccagccc caacatcgtg
      421 gtcatcctct gtggcaacaa gaaggacctg gatcctgagc gtgaggtcac tttcctagag
      481 gcttcccgct ttgctcagga gaatgagctg atgttcctgg agaccagcgc tctcacgggt
      541 gaaaacgtgg aagaagcttt cctgaagtgc gcacgcacca tcctcaacaa gatcgactca
      601 ggtgaactag atccggagag gatgggctca ggcattcagt atggtgacat atctcttcgc
      661 cagctgcggc agcctcgcag tgcccaggcc gtggcccctc agccctgtgg ctgctgagac
      721 gtgcagagcc agctcacctg ttcttctgga ccagccctgc tcgaaggctg gggctcagaa
      781 ccaggcccca agaggccagg ccccaatctg ccccagtccc agaaaagtta ctccatcacc
      841 catccccctc ccctggcctg ctggggcctg gctttggggc aagattgagc cacaggggaa
      901 aggggacccc atacctgctg ctgcttcctc tgtcttggct aactctagtc cccctccccg
      961 agcccctaac catacctgaa gaactcccaa agcttgagac cagggccaat tggccccaac
     1021 gtcctgcctg gccccgctgt tgcaagtctg tgttatttat tacctggagg cctgttccat
     1081 cctgtcccag tcctccataa agcattgttt acacctgtga aaaaaaaaaa
//
