LOCUS       NM_001024331            1189 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus RAB43, member RAS oncogene family (Rab43), mRNA.
ACCESSION   NM_001024331 XM_575598
VERSION     NM_001024331.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1189)
  AUTHORS   Gerondopoulos,A., Bastos,R.N., Yoshimura,S., Anderson,R.,
            Carpanini,S., Aligianis,I., Handley,M.T. and Barr,F.A.
  TITLE     Rab18 and a Rab18 GEF complex are required for normal ER structure
  JOURNAL   J Cell Biol 205 (5), 707-720 (2014)
   PUBMED   24891604
REFERENCE   2  (bases 1 to 1189)
  AUTHORS   Fujita,A., Koinuma,S., Yasuda,S., Nagai,H., Kamiguchi,H., Wada,N.
            and Nakamura,T.
  TITLE     GTP hydrolysis of TC10 promotes neurite outgrowth through exocytic
            fusion of Rab11- and L1-containing vesicles by releasing exocyst
            component Exo70
  JOURNAL   PLoS One 8 (11), e79689 (2013)
   PUBMED   24223996
  REMARK    GeneRIF: Exocytosis of Rab11- and L1-positive vesicles may play a
            central role in TC10-mediated neurite outgrowth
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1189)
  AUTHORS   Slater,L.H., Hett,E.C., Clatworthy,A.E., Mark,K.G. and Hung,D.T.
  TITLE     CCT chaperonin complex is required for efficient delivery of
            anthrax toxin into the cytosol of host cells
  JOURNAL   Proc Natl Acad Sci U S A 110 (24), 9932-9937 (2013)
   PUBMED   23716698
REFERENCE   4  (bases 1 to 1189)
  AUTHORS   Zenner,H.L., Yoshimura,S., Barr,F.A. and Crump,C.M.
  TITLE     Analysis of Rab GTPase-activating proteins indicates that Rab1a/b
            and Rab43 are important for herpes simplex virus 1 secondary
            envelopment
  JOURNAL   J Virol 85 (16), 8012-8021 (2011)
   PUBMED   21680502
REFERENCE   5  (bases 1 to 1189)
  AUTHORS   Seto,S., Tsujimura,K. and Koide,Y.
  TITLE     Rab GTPases regulating phagosome maturation are differentially
            recruited to mycobacterial phagosomes
  JOURNAL   Traffic 12 (4), 407-420 (2011)
   PUBMED   21255211
REFERENCE   6  (bases 1 to 1189)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   7  (bases 1 to 1189)
  AUTHORS   Trost,M., English,L., Lemieux,S., Courcelles,M., Desjardins,M. and
            Thibault,P.
  TITLE     The phagosomal proteome in interferon-gamma-activated macrophages
  JOURNAL   Immunity 30 (1), 143-154 (2009)
   PUBMED   19144319
REFERENCE   8  (bases 1 to 1189)
  AUTHORS   Haas,A.K., Yoshimura,S., Stephens,D.J., Preisinger,C., Fuchs,E. and
            Barr,F.A.
  TITLE     Analysis of GTPase-activating proteins: Rab1 and Rab43 are key Rabs
            required to maintain a functional Golgi complex in human cells
  JOURNAL   J Cell Sci 120 (Pt 17), 2997-3010 (2007)
   PUBMED   17684057
REFERENCE   9  (bases 1 to 1189)
  AUTHORS   Fuchs,E., Haas,A.K., Spooner,R.A., Yoshimura,S., Lord,J.M. and
            Barr,F.A.
  TITLE     Specific Rab GTPase-activating proteins define the Shiga toxin and
            epidermal growth factor uptake pathways
  JOURNAL   J Cell Biol 177 (6), 1133-1143 (2007)
   PUBMED   17562788
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Jun 3, 2021 this sequence version replaced NM_001024331.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY593256.1, SRR26643289.13476.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN12840107,
                                           SAMN16676787 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-307               JAXUCZ010000004.1  121826205-121826511 c
            308-491             JAXUCZ010000004.1  121809403-121809586 c
            492-1189            JAXUCZ010000004.1  121806992-121807689 c
FEATURES             Location/Qualifiers
     source          1..1189
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     gene            1..1189
                     /gene="Rab43"
                     /note="RAB43, member RAS oncogene family"
                     /db_xref="GeneID:500249"
                     /db_xref="RGD:1565300"
     exon            1..307
                     /gene="Rab43"
                     /inference="alignment:Splign:2.1.0"
     CDS             110..742
                     /gene="Rab43"
                     /note="Ras-related protein RAB43"
                     /codon_start=1
                     /product="ras-related protein Rab-43"
                     /protein_id="NP_001019502.1"
                     /db_xref="GeneID:500249"
                     /db_xref="RGD:1565300"
                     /translation="MAGPGPGDQDEHYDFLFKLVLVGDASVGKTCVVQRFKTGAFSAR
                     QGSTIGVDFTMKTLEIQGKRVKLQIWDTAGQERFRTITQSYYRSANGAILAYDISKRS
                     TFLSVPHWIEDVRKYAGSNIVQLLIGNKSDLADLREVPLAEAQSLAEHYDILCAIETS
                     AKDSSNVEEAFTRVATELIMRHGGPMFSEKNTDHIQLDSKDIAESWGCGC"
     exon            308..491
                     /gene="Rab43"
                     /inference="alignment:Splign:2.1.0"
     exon            492..1189
                     /gene="Rab43"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggccgctcc acgtagcccg gcgcggagcg ggctagaaca cagggacctc ggcccgcggc
       61 tgtcgtaagc ccaagacggg cccttgggtc ccaggactcc cgtggagcta tggcgggccc
      121 tggcccggga gaccaggacg aacactacga tttcctgttc aagctggtgt tagtgggcga
      181 cgcgagcgtg ggcaagacgt gcgtggtgca gcgcttcaag accggcgcct tctccgcgcg
      241 tcagggcagc accatcggtg tcgacttcac catgaagacg ctggagatcc agggcaagcg
      301 ggtcaagctc cagatttggg acacagccgg ccaggagcgg ttccggacca tcacccagag
      361 ctactaccga agtgccaatg gggctatcct cgcgtacgac atcagcaaga ggagcacctt
      421 cttgtcggtg cctcactgga ttgaggatgt gaggaagtac gcgggctcca acatcgtgca
      481 gctgctgatc gggaacaagt cagaccttgc tgatctccgg gaggtcccgc tggcggaggc
      541 gcagagcctg gctgagcact atgacatcct ctgtgccatc gagacctctg ccaaggactc
      601 cagcaatgtg gaggaggcct tcaccagagt ggccactgaa ctcatcatga ggcatggagg
      661 ccccatgttc agtgagaaga acactgacca cattcagctg gacagcaagg acattgcgga
      721 gagctggggc tgtggatgct gactgggggg gcagggcagg ccggctaaga cctcccctcc
      781 tcctttgtct gcagcctgtc aagacccacc cctcagagtc agccctccag ggcactggct
      841 tctctagagg gattctgcac ccctagcctg gatgctgggt aggaagggaa atgcagggag
      901 tgtatcctgt gcagaaggct attggcccag ggccgaatgt ggaccatccc acaagccagc
      961 atctgctgcc tccgtgtttg tcacattcca gggctagcct gagccttcca gcagactgtg
     1021 gtgggaaatg ggctggctgc ggggcccagc cctgcgtgct ggttttgacc ttctcctgcc
     1081 ttgactgccg caggctgctg ctctccaggg atgtggctgg taccccaggt tctttcttcc
     1141 aggtcattct cctgcctctt accaaagcat aaaaagcaca tcaattaga
//
