LOCUS       NM_017313               1707 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus RAB3A interacting protein (Rab3ip), mRNA.
ACCESSION   NM_017313
VERSION     NM_017313.3
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1707)
  AUTHORS   Vetter,M., Stehle,R., Basquin,C. and Lorentzen,E.
  TITLE     Structure of Rab11-FIP3-Rabin8 reveals simultaneous binding of FIP3
            and Rabin8 effectors to Rab11
  JOURNAL   Nat Struct Mol Biol 22 (9), 695-702 (2015)
   PUBMED   26258637
REFERENCE   2  (bases 1 to 1707)
  AUTHORS   Klip,A., Sun,Y., Chiu,T.T. and Foley,K.P.
  TITLE     Signal transduction meets vesicle traffic: the software and
            hardware of GLUT4 translocation
  JOURNAL   Am J Physiol Cell Physiol 306 (10), C879-C886 (2014)
   PUBMED   24598362
  REMARK    Review article
REFERENCE   3  (bases 1 to 1707)
  AUTHORS   Chiba,S., Amagai,Y., Homma,Y., Fukuda,M. and Mizuno,K.
  TITLE     NDR2-mediated Rabin8 phosphorylation is crucial for ciliogenesis by
            switching binding specificity from phosphatidylserine to Sec15
  JOURNAL   EMBO J 32 (6), 874-885 (2013)
   PUBMED   23435566
REFERENCE   4  (bases 1 to 1707)
  AUTHORS   Blumer,J., Rey,J., Dehmelt,L., Mazel,T., Wu,Y.W., Bastiaens,P.,
            Goody,R.S. and Itzen,A.
  TITLE     RabGEFs are a major determinant for specific Rab membrane targeting
  JOURNAL   J Cell Biol 200 (3), 287-300 (2013)
   PUBMED   23382462
REFERENCE   5  (bases 1 to 1707)
  AUTHORS   Ultanir,S.K., Hertz,N.T., Li,G., Ge,W.P., Burlingame,A.L.,
            Pleasure,S.J., Shokat,K.M., Jan,L.Y. and Jan,Y.N.
  TITLE     Chemical genetic identification of NDR1/2 kinase substrates AAK1
            and Rabin8 Uncovers their roles in dendrite arborization and spine
            development
  JOURNAL   Neuron 73 (6), 1127-1142 (2012)
   PUBMED   22445341
REFERENCE   6  (bases 1 to 1707)
  AUTHORS   Hattula,K., Furuhjelm,J., Arffman,A. and Peranen,J.
  TITLE     A Rab8-specific GDP/GTP exchange factor is involved in actin
            remodeling and polarized membrane transport
  JOURNAL   Mol Biol Cell 13 (9), 3268-3280 (2002)
   PUBMED   12221131
REFERENCE   7  (bases 1 to 1707)
  AUTHORS   de Bruijn,D.R., dos Santos,N.R., Kater-Baats,E., Thijssen,J., van
            den Berk,L., Stap,J., Balemans,M., Schepens,M., Merkx,G. and van
            Kessel,A.G.
  TITLE     The cancer-related protein SSX2 interacts with the human homologue
            of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear
            protein, SSX2IP
  JOURNAL   Genes Chromosomes Cancer 34 (3), 285-298 (2002)
   PUBMED   12007189
REFERENCE   8  (bases 1 to 1707)
  AUTHORS   Page,G., Kogel,D., Rangnekar,V. and Scheidtmann,K.H.
  TITLE     Interaction partners of Dlk/ZIP kinase: co-expression of Dlk/ZIP
            kinase and Par-4 results in cytoplasmic retention and apoptosis
  JOURNAL   Oncogene 18 (51), 7265-7273 (1999)
   PUBMED   10602480
REFERENCE   9  (bases 1 to 1707)
  AUTHORS   Page,G., Lodige,I., Kogel,D. and Scheidtmann,K.H.
  TITLE     AATF, a novel transcription factor that interacts with Dlk/ZIP
            kinase and interferes with apoptosis
  JOURNAL   FEBS Lett 462 (1-2), 187-191 (1999)
   PUBMED   10580117
REFERENCE   10 (bases 1 to 1707)
  AUTHORS   Brondyk,W.H., McKiernan,C.J., Fortner,K.A., Stabila,P., Holz,R.W.
            and Macara,I.G.
  TITLE     Interaction cloning of Rabin3, a novel protein that associates with
            the Ras-like GTPase Rab3A
  JOURNAL   Mol Cell Biol 15 (3), 1137-1143 (1995)
   PUBMED   7532276
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC127500.1.
            
            On Aug 30, 2012 this sequence version replaced NM_017313.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC127500.1, U19181.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1707              BC127500.1         4-1710
FEATURES             Location/Qualifiers
     source          1..1707
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q22"
     gene            1..1707
                     /gene="Rab3ip"
                     /gene_synonym="RABIN3"
                     /note="RAB3A interacting protein"
                     /db_xref="GeneID:29885"
                     /db_xref="RGD:620650"
     exon            1..282
                     /gene="Rab3ip"
                     /gene_synonym="RABIN3"
                     /inference="alignment:Splign:2.1.0"
     CDS             32..1414
                     /gene="Rab3ip"
                     /gene_synonym="RABIN3"
                     /note="rabin-3; SSX2-interacting protein;
                     rab3A-interacting protein"
                     /codon_start=1
                     /product="rab-3A-interacting protein"
                     /protein_id="NP_059009.2"
                     /db_xref="GeneID:29885"
                     /db_xref="RGD:620650"
                     /translation="MANDPLEGFHEVNLASPTSPDLLGVCDPGTQEQTTSPSVIYRPH
                     PSTLCSATIQANALNLSDLPTQPVYSSPRHLNCAEISNISIHVPEPASSVASEVAAGL
                     TRFTSRKDSCNAEREFLQGATVTEASAGNDDIFGLSTDSLSRLRSPSVLEVREKGYER
                     LKEELAKAQRELKLKDEECERLSKVRDQLGQELEELTASLFEEAHKMVREANVKQATA
                     EKQLKEAQGKIDVLQAEVAALKTLVLSSSPTSPTQEPLAAGKTPFKRGHTRNKSTSSA
                     MSGSHQDFSAIQPIVKDCREADLSLYNEFRSWKDEPTMDRTCPFLDKIYQEDIFPCLT
                     FAKSELASAVLEAVENNTLSIEPVGLQPIRFVKASAVECGGPKKCALTGQSKPCKHRI
                     KLGDSSSYYYISPVCRYRITSVCNFFTYIRYIQQGLVKQQDVDQMFWEVMQLRKEMSL
                     AKLGYFKEEL"
     exon            283..541
                     /gene="Rab3ip"
                     /gene_synonym="RABIN3"
                     /inference="alignment:Splign:2.1.0"
     exon            542..637
                     /gene="Rab3ip"
                     /gene_synonym="RABIN3"
                     /inference="alignment:Splign:2.1.0"
     exon            638..715
                     /gene="Rab3ip"
                     /gene_synonym="RABIN3"
                     /inference="alignment:Splign:2.1.0"
     exon            716..919
                     /gene="Rab3ip"
                     /gene_synonym="RABIN3"
                     /inference="alignment:Splign:2.1.0"
     exon            920..1048
                     /gene="Rab3ip"
                     /gene_synonym="RABIN3"
                     /inference="alignment:Splign:2.1.0"
     exon            1049..1161
                     /gene="Rab3ip"
                     /gene_synonym="RABIN3"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1261
                     /gene="Rab3ip"
                     /gene_synonym="RABIN3"
                     /inference="alignment:Splign:2.1.0"
     exon            1262..1331
                     /gene="Rab3ip"
                     /gene_synonym="RABIN3"
                     /inference="alignment:Splign:2.1.0"
     exon            1332..1680
                     /gene="Rab3ip"
                     /gene_synonym="RABIN3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcttaggct gtcctatgat gaagtcttgc tatggctaac gaccccttag aaggtttcca
       61 tgaagtgaac ctcgcttcgc ctacctctcc agaccttctt ggtgtgtgtg acccgggaac
      121 ccaagagcag actacctccc cgagcgtcat ctaccggcca cacccttcga cgttgtgctc
      181 tgccactatc caggccaatg ccttaaatct ttctgacctt cccacacagc ctgtgtattc
      241 atccccgagg catttaaact gtgcagaaat atctaacatc agcattcatg ttccagagcc
      301 agcatcatcg gtagcctctg aggtggcagc agggctcacg aggttcacct caaggaagga
      361 cagctgcaac gcagagaggg agtttctgca gggcgccacc gtcacagagg cttctgctgg
      421 caacgatgac atctttgggt tgagcacgga cagcctgtcc cgtttacgga gcccatctgt
      481 tctggaagtt agagagaagg gctacgaaag gttaaaagaa gaacttgcaa aagctcagag
      541 ggaattgaag ttaaaagatg aagaatgtga gagactttcg aaagtgcgag atcaacttgg
      601 gcaggagttg gaagaactca cagctagttt atttgaggaa gctcacaaga tggtgagaga
      661 ggcgaacgtc aagcaggcaa ctgcagaaaa gcagctgaag gaagctcaag ggaaaattga
      721 tgtgcttcaa gccgaagtgg ctgcgctgaa gacactcgta ctgtccagtt ctccaacatc
      781 gcctacgcag gagcctctgg cggctggaaa gacgcccttt aaaagggggc acacacggaa
      841 caaaagtaca agcagtgcta tgagtggcag ccaccaggac ttcagtgcga tccagccaat
      901 cgtaaaagac tgcagagagg ccgatctatc gctgtataat gagttcaggt cttggaagga
      961 tgagcccaca atggacagaa catgtccctt cctagacaaa atctatcagg aggatatctt
     1021 tccatgctta acattcgcga aaagtgagtt ggcttcagct gttctggagg ccgtggagaa
     1081 caacactcta agcatcgagc cggtagggtt gcagcccatc cgcttcgtga aggcttccgc
     1141 ggtggagtgc ggagggccaa aaaagtgtgc tctcactggc cagagtaagc cctgtaagca
     1201 caggattaaa ctaggggact ccagcagcta ttactacatc tctccggttt gcagataccg
     1261 gatcacttct gtatgtaact tttttacata cattcgatat attcagcagg gacttgtgaa
     1321 acagcaggat gttgatcaga tgttctggga agttatgcaa ctaagaaagg agatgtcgtt
     1381 ggcaaagctg ggatatttca aagaagaact ctgatgccct gagtacgggg ccgtgcgtgc
     1441 tcctccctgg acagctgaag gatgacaacg tttttatggt tactcaatat ttatttctaa
     1501 ggagaaggcc aaagacttcc ctcctctgca caccacacta tgaagtgctg tgattttttt
     1561 caaactgact gagctgtact tgcttatccc ttaatggaac acactctgaa gattgcaggc
     1621 ctgctagtga tggtaattca acactgcaaa tccagaccac caaataaaca ccagactgaa
     1681 aaaaaaaaaa aaaaaaaaaa aaaaaaa
//
