LOCUS       NM_133536                997 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Rattus norvegicus RAB3C, member RAS oncogene family (Rab3c), mRNA.
ACCESSION   NM_133536
VERSION     NM_133536.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 997)
  AUTHORS   Gerondopoulos,A., Bastos,R.N., Yoshimura,S., Anderson,R.,
            Carpanini,S., Aligianis,I., Handley,M.T. and Barr,F.A.
  TITLE     Rab18 and a Rab18 GEF complex are required for normal ER structure
  JOURNAL   J Cell Biol 205 (5), 707-720 (2014)
   PUBMED   24891604
REFERENCE   2  (bases 1 to 997)
  AUTHORS   Lindsay,A.J., Jollivet,F., Horgan,C.P., Khan,A.R., Raposo,G.,
            McCaffrey,M.W. and Goud,B.
  TITLE     Identification and characterization of multiple novel Rab-myosin Va
            interactions
  JOURNAL   Mol Biol Cell 24 (21), 3420-3434 (2013)
   PUBMED   24006491
REFERENCE   3  (bases 1 to 997)
  AUTHORS   Pavlos,N.J., Cheng,T.S., Qin,A., Ng,P.Y., Feng,H.T., Ang,E.S.,
            Carrello,A., Sung,C.H., Jahn,R., Zheng,M.H. and Xu,J.
  TITLE     Tctex-1, a novel interaction partner of Rab3D, is required for
            osteoclastic bone resorption
  JOURNAL   Mol Cell Biol 31 (7), 1551-1564 (2011)
   PUBMED   21262767
REFERENCE   4  (bases 1 to 997)
  AUTHORS   Zou,L., Zhou,J., Zhang,J., Li,J., Liu,N., Chai,L., Li,N., Liu,T.,
            Li,L., Xie,Z., Liu,H., Wan,Y. and Wu,Y.
  TITLE     The GTPase Rab3b/3c-positive recycling vesicles are involved in
            cross-presentation in dendritic cells
  JOURNAL   Proc Natl Acad Sci U S A 106 (37), 15801-15806 (2009)
   PUBMED   19717423
REFERENCE   5  (bases 1 to 997)
  AUTHORS   Riedel,D., Antonin,W., Fernandez-Chacon,R., Alvarez de Toledo,G.,
            Jo,T., Geppert,M., Valentijn,J.A., Valentijn,K., Jamieson,J.D.,
            Sudhof,T.C. and Jahn,R.
  TITLE     Rab3D is not required for exocrine exocytosis but for maintenance
            of normally sized secretory granules
  JOURNAL   Mol Cell Biol 22 (18), 6487-6497 (2002)
   PUBMED   12192047
REFERENCE   6  (bases 1 to 997)
  AUTHORS   Wada,M., Nakanishi,H., Satoh,A., Hirano,H., Obaishi,H., Matsuura,Y.
            and Takai,Y.
  TITLE     Isolation and characterization of a GDP/GTP exchange protein
            specific for the Rab3 subfamily small G proteins
  JOURNAL   J Biol Chem 272 (7), 3875-3878 (1997)
   PUBMED   9020086
REFERENCE   7  (bases 1 to 997)
  AUTHORS   Viggeswarapu,M. and Wildey,G.M.
  TITLE     Cloning and tissue expression of the rat RAB 3C GTP-binding protein
  JOURNAL   Biochem Biophys Res Commun 227 (3), 645-650 (1996)
   PUBMED   8885988
REFERENCE   8  (bases 1 to 997)
  AUTHORS   Madison,D.L., Kruger,W.H., Kim,T. and Pfeiffer,S.E.
  TITLE     Differential expression of rab3 isoforms in oligodendrocytes and
            astrocytes
  JOURNAL   J Neurosci Res 45 (3), 258-268 (1996)
   PUBMED   8841986
REFERENCE   9  (bases 1 to 997)
  AUTHORS   Fischer von Mollard,G., Stahl,B., Khokhlatchev,A., Sudhof,T.C. and
            Jahn,R.
  TITLE     Rab3C is a synaptic vesicle protein that dissociates from synaptic
            vesicles after stimulation of exocytosis
  JOURNAL   J Biol Chem 269 (15), 10971-10974 (1994)
   PUBMED   8157621
REFERENCE   10 (bases 1 to 997)
  AUTHORS   Cormont,M., Tanti,J.F., Zahraoui,A., Van Obberghen,E., Tavitian,A.
            and Le Marchand-Brustel,Y.
  TITLE     Insulin and okadaic acid induce Rab4 redistribution in adipocytes
  JOURNAL   J Biol Chem 268 (26), 19491-19497 (1993)
   PUBMED   8366094
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from U54807.1.
            
            [WARNING] On Oct 10, 2024 this sequence was replaced by
            NM_133536.3.
            
            On Aug 31, 2012 this sequence version replaced NM_133536.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U54807.1, D78197.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132291, SAMD00132292
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-997               U54807.1           5-1001
FEATURES             Location/Qualifiers
     source          1..997
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q14"
     gene            1..997
                     /gene="Rab3c"
                     /note="RAB3C, member RAS oncogene family"
                     /db_xref="GeneID:171058"
                     /db_xref="RGD:620923"
     exon            1..109
                     /gene="Rab3c"
                     /inference="alignment:Splign:2.1.0"
     CDS             86..769
                     /gene="Rab3c"
                     /codon_start=1
                     /product="ras-related protein Rab-3C"
                     /protein_id="NP_598220.1"
                     /db_xref="GeneID:171058"
                     /db_xref="RGD:620923"
                     /translation="MRHEAPMQMASAQDARFGQKDSSDQNFDYMFKLLIIGNSSVGKT
                     SFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRG
                     AMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILVGNKCDMEDERVVSTERGRH
                     LGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLETDPAITGAKQSTRLKETP
                     PPPQPNCGC"
     exon            110..337
                     /gene="Rab3c"
                     /inference="alignment:Splign:2.1.0"
     exon            338..456
                     /gene="Rab3c"
                     /inference="alignment:Splign:2.1.0"
     exon            457..581
                     /gene="Rab3c"
                     /inference="alignment:Splign:2.1.0"
     exon            582..997
                     /gene="Rab3c"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcagagagcg ctcaggctgt gcacgcttga ccaggctccc ggaccagagc tgtcctagca
       61 agagagaaaa ggacatttgc ctacaatgag acacgaggcg cccatgcaga tggcctcggc
      121 acaagatgcc aggtttggtc agaaagactc ttctgaccag aacttcgact acatgttcaa
      181 gttgctgatc attggcaata gcagcgtggg caaaacatcc ttcctgttcc gctatgctga
      241 tgactccttc acgtctgcct ttgtcagcac ggtcggcatc gatttcaaag taaaaactgt
      301 cttcaaaaat gaaaagagaa tcaagcttca gatttgggac acagcaggcc aggaaagata
      361 caggaccatc accacagcct attatcgagg ggccatgggc ttcattttaa tgtatgacat
      421 cacaaatgaa gaatccttca acgctgtaca agattggtca actcagatca aaacatattc
      481 ctgggataat gcccaggtta tactggtcgg aaacaaatgt gacatggaag acgaacgggt
      541 ggtctcaact gagagagggc gccacttagg agagcagctc gggtttgagt tttttgaaac
      601 cagcgccaag gataacatca acgtgaagca aacctttgag cgcctcgtag atatcatctg
      661 tgacaaaatg tcagagagct tggagactga cccagccatc acaggcgcca agcagagcac
      721 gaggctcaag gaaacccctc ctccaccaca gcccaactgt ggctgctaat gtccccccgc
      781 acaggagctc caagggcccc cagagcagcc aagaaaccgc atttataaat ggtctattag
      841 ccttcaatca tactgcctaa taattatttg aaggaagtct ttgatgtcag tggcccatat
      901 atgcattcaa accgtgagca atttcctgtg gtaatatgtg gcgaatttgc tcttatattt
      961 gtaaggatta ttcatctata aacacctgct acttgca
//
