LOCUS       NM_031091               1159 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus RAB3B, member RAS oncogene family (Rab3b), mRNA.
ACCESSION   NM_031091
VERSION     NM_031091.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1159)
  AUTHORS   Gerondopoulos,A., Bastos,R.N., Yoshimura,S., Anderson,R.,
            Carpanini,S., Aligianis,I., Handley,M.T. and Barr,F.A.
  TITLE     Rab18 and a Rab18 GEF complex are required for normal ER structure
  JOURNAL   J Cell Biol 205 (5), 707-720 (2014)
   PUBMED   24891604
REFERENCE   2  (bases 1 to 1159)
  AUTHORS   Lindsay,A.J., Jollivet,F., Horgan,C.P., Khan,A.R., Raposo,G.,
            McCaffrey,M.W. and Goud,B.
  TITLE     Identification and characterization of multiple novel Rab-myosin Va
            interactions
  JOURNAL   Mol Biol Cell 24 (21), 3420-3434 (2013)
   PUBMED   24006491
REFERENCE   3  (bases 1 to 1159)
  AUTHORS   Zhang,W., Shen,Y., Jiao,R., Liu,Y., Deng,L. and Qi,C.
  TITLE     Crystal structure of inactive form of Rab3B
  JOURNAL   Biochem Biophys Res Commun 418 (4), 841-844 (2012)
   PUBMED   22321395
REFERENCE   4  (bases 1 to 1159)
  AUTHORS   Pavlos,N.J., Cheng,T.S., Qin,A., Ng,P.Y., Feng,H.T., Ang,E.S.,
            Carrello,A., Sung,C.H., Jahn,R., Zheng,M.H. and Xu,J.
  TITLE     Tctex-1, a novel interaction partner of Rab3D, is required for
            osteoclastic bone resorption
  JOURNAL   Mol Cell Biol 31 (7), 1551-1564 (2011)
   PUBMED   21262767
REFERENCE   5  (bases 1 to 1159)
  AUTHORS   Pavlos,N.J., Gronborg,M., Riedel,D., Chua,J.J., Boyken,J.,
            Kloepper,T.H., Urlaub,H., Rizzoli,S.O. and Jahn,R.
  TITLE     Quantitative analysis of synaptic vesicle Rabs uncovers distinct
            yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered
            exocytosis
  JOURNAL   J Neurosci 30 (40), 13441-13453 (2010)
   PUBMED   20926670
REFERENCE   6  (bases 1 to 1159)
  AUTHORS   Wang,Y., Okamoto,M., Schmitz,F., Hofmann,K. and Sudhof,T.C.
  TITLE     Rim is a putative Rab3 effector in regulating synaptic-vesicle
            fusion
  JOURNAL   Nature 388 (6642), 593-598 (1997)
   PUBMED   9252191
REFERENCE   7  (bases 1 to 1159)
  AUTHORS   Klengel,R., Piiper,A., Pittelkow,S. and Zeuzem,S.
  TITLE     Differential expression of Rab3 isoforms during differentiation of
            pancreatic acinar cell line AR42J
  JOURNAL   Biochem Biophys Res Commun 236 (3), 719-722 (1997)
   PUBMED   9245721
REFERENCE   8  (bases 1 to 1159)
  AUTHORS   Brondyk,W.H., McKiernan,C.J., Fortner,K.A., Stabila,P., Holz,R.W.
            and Macara,I.G.
  TITLE     Interaction cloning of Rabin3, a novel protein that associates with
            the Ras-like GTPase Rab3A
  JOURNAL   Mol Cell Biol 15 (3), 1137-1143 (1995)
   PUBMED   7532276
REFERENCE   9  (bases 1 to 1159)
  AUTHORS   Oberhauser,A.F., Balan,V., Fernandez-Badilla,C.L. and
            Fernandez,J.M.
  TITLE     RT-PCR cloning of Rab3 isoforms expressed in peritoneal mast cells
  JOURNAL   FEBS Lett 339 (1-2), 171-174 (1994)
   PUBMED   7508866
REFERENCE   10 (bases 1 to 1159)
  AUTHORS   Cormont,M., Tanti,J.F., Zahraoui,A., Van Obberghen,E., Tavitian,A.
            and Le Marchand-Brustel,Y.
  TITLE     Insulin and okadaic acid induce Rab4 redistribution in adipocytes
  JOURNAL   J Biol Chem 268 (26), 19491-19497 (1993)
   PUBMED   8366094
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB711467.1, Y14019.1, BF524240.1 and BI293875.1.
            
            On Oct 13, 2005 this sequence version replaced NM_031091.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ094237.1, CF977058.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132266
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-206               CB711467.1         12-217
            207-772             Y14019.1           95-660
            773-986             BF524240.1         8-221               c
            987-1159            BI293875.1         1-173               c
FEATURES             Location/Qualifiers
     source          1..1159
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q34"
     gene            1..1159
                     /gene="Rab3b"
                     /note="RAB3B, member RAS oncogene family"
                     /db_xref="GeneID:81755"
                     /db_xref="RGD:620922"
     exon            1..112
                     /gene="Rab3b"
                     /inference="alignment:Splign:2.1.0"
     CDS             113..772
                     /gene="Rab3b"
                     /codon_start=1
                     /product="ras-related protein Rab-3B"
                     /protein_id="NP_112353.1"
                     /db_xref="GeneID:81755"
                     /db_xref="RGD:620922"
                     /translation="MASVTDGNTGIRDASDQNFDYMFKLLIIGNSSVGKTSFLFRYAD
                     DTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMY
                     DITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEERVIPTEKGRLLAEQLGFD
                     FFEASAKENISVRQAFERLVDAICDKMSDSMDTDPSVLGASKTTRLSDTPPLLQQNCS
                     C"
     exon            113..340
                     /gene="Rab3b"
                     /inference="alignment:Splign:2.1.0"
     exon            341..459
                     /gene="Rab3b"
                     /inference="alignment:Splign:2.1.0"
     exon            460..584
                     /gene="Rab3b"
                     /inference="alignment:Splign:2.1.0"
     exon            585..1142
                     /gene="Rab3b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcaaccctcc gtagccgagg tgggaaccag acccgccccg cctgcctctc gtccactact
       61 gccaggtgca acagtccggc tgcagtgtgc cgcgagccag ctcttatccg agatggcctc
      121 agtaactgat ggtaacactg gaatcagaga tgcctctgac cagaactttg actacatgtt
      181 caaactgctc atcattggca acagcagcgt cgggaagacc tccttccttt tccgctatgc
      241 tgatgacacc ttcacccctg cctttgtcag cactgtgggt atcgacttca aagtgaagac
      301 agtttaccgt catgagaagc gtgtgaagct gcagatatgg gacacggcag ggcaagagcg
      361 gtaccggacc atcaccacag cctactaccg cggggccatg ggcttcattc tcatgtatga
      421 catcaccaac gaggagtcct tcaacgctgt ccaggactgg gctactcaga tcaagaccta
      481 ctcctgggac aacgcacagg tcattctcgt ggggaataaa tgtgatatgg aagaggaaag
      541 ggtgatcccg actgagaagg gccggctcct agcagagcaa cttgggtttg acttctttga
      601 agccagtgcc aaggagaaca tcagtgtgag gcaggccttc gagcgtctgg tggacgccat
      661 ctgcgataag atgtctgact caatggacac agacccctcc gtgctgggcg cctccaagac
      721 cacacggctc tcggacaccc cgccgctgct ccagcagaac tgctcttgct aggcaaggcc
      781 cgccctgctg ttccccccat gtcatgccca cttctcctct gcttctctct gttactgtct
      841 gctccccgaa ccccaagcca gctgagttct ttgccagccc ctgtggttct ctgcagacgg
      901 ccccagctac agatactaac tgcaggttac tgtgtgggtg aagactcctc ttacaacaga
      961 aaactccctc ttaggaagga ggttcaacat agagacttgg aaagaacctt ttctgccctt
     1021 aaaataaaat tcccttcatt taccaagata caactcccac acgcactcct taggggttga
     1081 ccagtgtgta aagtgaggcc cacctgcaca gctgatacta ttaaagaaaa tgtctcaaag
     1141 caaaaaaaaa aaaaaaaaa
//
