LOCUS       NM_001037645            1189 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus RAB2B, member RAS oncogene family (Rab2b), mRNA.
ACCESSION   NM_001037645 XM_223991
VERSION     NM_001037645.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1189)
  AUTHORS   Pavlos,N.J., Gronborg,M., Riedel,D., Chua,J.J., Boyken,J.,
            Kloepper,T.H., Urlaub,H., Rizzoli,S.O. and Jahn,R.
  TITLE     Quantitative analysis of synaptic vesicle Rabs uncovers distinct
            yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered
            exocytosis
  JOURNAL   J Neurosci 30 (40), 13441-13453 (2010)
   PUBMED   20926670
REFERENCE   2  (bases 1 to 1189)
  AUTHORS   Ostrowski,M., Carmo,N.B., Krumeich,S., Fanget,I., Raposo,G.,
            Savina,A., Moita,C.F., Schauer,K., Hume,A.N., Freitas,R.P.,
            Goud,B., Benaroch,P., Hacohen,N., Fukuda,M., Desnos,C.,
            Seabra,M.C., Darchen,F., Amigorena,S., Moita,L.F. and Thery,C.
  TITLE     Rab27a and Rab27b control different steps of the exosome secretion
            pathway
  JOURNAL   Nat Cell Biol 12 (1), 19-30 (2010)
   PUBMED   19966785
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC107443.1.
            
            On Dec 10, 2005 this sequence version replaced XM_223991.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC107443.1, CO400340.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1189
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p14"
     gene            1..1189
                     /gene="Rab2b"
                     /note="RAB2B, member RAS oncogene family"
                     /db_xref="GeneID:305853"
                     /db_xref="RGD:1309117"
     exon            1..142
                     /gene="Rab2b"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..744
                     /gene="Rab2b"
                     /EC_number="3.6.5.2"
                     /codon_start=1
                     /product="ras-related protein Rab-2B"
                     /protein_id="NP_001032734.1"
                     /db_xref="GeneID:305853"
                     /db_xref="RGD:1309117"
                     /translation="MTYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFG
                     ARMVNIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLE
                     DARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAY
                     INTAKEIHRKIQQGLFDVHNEANGIKIGPQQSISLVGPCPSQQNSSDIGPDSGCC"
     exon            143..214
                     /gene="Rab2b"
                     /inference="alignment:Splign:2.1.0"
     exon            215..282
                     /gene="Rab2b"
                     /inference="alignment:Splign:2.1.0"
     exon            283..365
                     /gene="Rab2b"
                     /inference="alignment:Splign:2.1.0"
     exon            366..458
                     /gene="Rab2b"
                     /inference="alignment:Splign:2.1.0"
     exon            459..570
                     /gene="Rab2b"
                     /inference="alignment:Splign:2.1.0"
     exon            571..639
                     /gene="Rab2b"
                     /inference="alignment:Splign:2.1.0"
     exon            640..1181
                     /gene="Rab2b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcaaataag gagatccgta gattgagcgg ctagagaggt cggaggtaag tggctgtgga
       61 aatcgggagg acccggaaca ccgacacctc gggaccatga cttacgctta tctcttcaag
      121 tacatcatca tcggagacac aggtgtgggg aagtcatgtc tcctccttca gtttaccgac
      181 aagcggttcc agcctgtgca cgacctcaca ataggtgtgg agtttggagc acgtatggtc
      241 aacatcgatg gaaagcaaat caaactgcaa atctgggata cggctgggca agagtccttc
      301 cgttctatca cccgttccta ctacagggga gcagctggag ccctgctggt gtatgacatc
      361 acaagacgtg aaaccttcaa ccacctgacc tcatggttag aggatgcccg ccagcactcc
      421 agctccaaca tggttataat gctgattggg aataagagtg atctagaatc tcgaagggat
      481 gtgaaaagag aagaaggaga ggcctttgct cgtgagcatg gccttatatt catggaaaca
      541 tcagccaaga cagcctgcaa tgtcgaagag gcctacatta atacagccaa agaaatacat
      601 aggaagatcc agcaaggttt atttgatgtc cacaatgagg caaacggcat caagattggg
      661 ccccagcagt cgatctcatt ggtggggcca tgcccctctc agcagaactc ctccgacata
      721 gggcctgact ctggctgctg ctgaacacct ggcctgaact ctctgttttt cctctcctgg
      781 aacagtttca gatcagtcag cttaacaaaa gaggtcttcc ttgctttggc tgagagcagc
      841 ctcttttcag tgcgatttca cccttccact taaaacacga ggagaaaact gggccctttc
      901 agacctgtcc tcctttcggg acatgagcat tctgcctaga ctacgactct ttcatcctct
      961 agtttctaaa atgttaggat caaagctgat tgtcgcggta gtcaagcaaa caacctacta
     1021 agatcaacat ctatttgcta tgcgtgatgg cacataccca taattccagc actggggact
     1081 tttggcggaa ggattgccag gagttttgaa gtcagtctgg actacataag tttcactagg
     1141 ccatatgttt aaaaaagcca aaaagaaaaa aaaaaaaaaa aaaaaaaaa
//
