LOCUS       NM_133590               1251 bp    mRNA    linear   ROD 11-DEC-2024
DEFINITION  Rattus norvegicus RAB29, member RAS oncogene family (Rab29), mRNA.
ACCESSION   NM_133590
VERSION     NM_133590.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1251)
  AUTHORS   Tan,X., Wei,Y., Cao,J., Wu,D., Lai,N., Deng,R., Li,H., Shen,H.,
            Peng,Y., Li,X. and Chen,G.
  TITLE     RAB7L1 Participates in Secondary Brain Injury Induced by
            Experimental Intracerebral Hemorrhage in Rats
  JOURNAL   J Mol Neurosci 71 (1), 9-18 (2021)
   PUBMED   32691280
  REMARK    GeneRIF: RAB7L1 Participates in Secondary Brain Injury Induced by
            Experimental Intracerebral Hemorrhage in Rats.
REFERENCE   2  (bases 1 to 1251)
  AUTHORS   Onnis,A., Finetti,F., Patrussi,L., Gottardo,M., Cassioli,C.,
            Spano,S. and Baldari,C.T.
  TITLE     The small GTPase Rab29 is a common regulator of immune synapse
            assembly and ciliogenesis
  JOURNAL   Cell Death Differ 22 (10), 1687-1699 (2015)
   PUBMED   26021297
REFERENCE   3  (bases 1 to 1251)
  AUTHORS   Ortiz-Sandoval,C.G., Hughes,S.C., Dacks,J.B. and Simmen,T.
  TITLE     Interaction with the effector dynamin-related protein 1 (Drp1) is
            an ancient function of Rab32 subfamily proteins
  JOURNAL   Cell Logist 4 (4), e986399 (2014)
   PUBMED   25767741
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1251)
  AUTHORS   Wang,S., Ma,Z., Xu,X., Wang,Z., Sun,L., Zhou,Y., Lin,X., Hong,W.
            and Wang,T.
  TITLE     A role of Rab29 in the integrity of the trans-Golgi network and
            retrograde trafficking of mannose-6-phosphate receptor
  JOURNAL   PLoS One 9 (5), e96242 (2014)
   PUBMED   24788816
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1251)
  AUTHORS   Beilina,A., Rudenko,I.N., Kaganovich,A., Civiero,L., Chau,H.,
            Kalia,S.K., Kalia,L.V., Lobbestael,E., Chia,R., Ndukwe,K., Ding,J.,
            Nalls,M.A., Olszewski,M., Hauser,D.N., Kumaran,R., Lozano,A.M.,
            Baekelandt,V., Greene,L.E., Taymans,J.M., Greggio,E. and
            Cookson,M.R.
  CONSRTM   International Parkinson's Disease Genomics Consortium; North
            American Brain Expression Consortium
  TITLE     Unbiased screen for interactors of leucine-rich repeat kinase 2
            supports a common pathway for sporadic and familial Parkinson
            disease
  JOURNAL   Proc Natl Acad Sci U S A 111 (7), 2626-2631 (2014)
   PUBMED   24510904
REFERENCE   6  (bases 1 to 1251)
  AUTHORS   MacLeod,D.A., Rhinn,H., Kuwahara,T., Zolin,A., Di Paolo,G.,
            McCabe,B.D., Marder,K.S., Honig,L.S., Clark,L.N., Small,S.A. and
            Abeliovich,A.
  TITLE     RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting
            and Parkinson's disease risk
  JOURNAL   Neuron 77 (3), 425-439 (2013)
   PUBMED   23395371
  REMARK    Erratum:[Neuron. 2013 Mar 6;77(5):994. MacCabe, Brian D [corrected
            to McCabe, Brian D]]
REFERENCE   7  (bases 1 to 1251)
  AUTHORS   Spano,S., Liu,X. and Galan,J.E.
  TITLE     Proteolytic targeting of Rab29 by an effector protein distinguishes
            the intracellular compartments of human-adapted and broad-host
            Salmonella
  JOURNAL   Proc Natl Acad Sci U S A 108 (45), 18418-18423 (2011)
   PUBMED   22042847
REFERENCE   8  (bases 1 to 1251)
  AUTHORS   Berger,K.L., Cooper,J.D., Heaton,N.S., Yoon,R., Oakland,T.E.,
            Jordan,T.X., Mateu,G., Grakoui,A. and Randall,G.
  TITLE     Roles for endocytic trafficking and phosphatidylinositol 4-kinase
            III alpha in hepatitis C virus replication
  JOURNAL   Proc Natl Acad Sci U S A 106 (18), 7577-7582 (2009)
   PUBMED   19376974
REFERENCE   9  (bases 1 to 1251)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   10 (bases 1 to 1251)
  AUTHORS   Massmann,S., Schurmann,A. and Joost,H.G.
  TITLE     Cloning of two splicing variants of the novel Ras-related GTPase
            Rab29 which is predominantly expressed in kidney
  JOURNAL   Biochim Biophys Acta 1352 (1), 48-55 (1997)
   PUBMED   9177482
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from X96663.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X96663.1, FQ233577.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132263, SAMD00132264
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1251
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q13"
     gene            1..1251
                     /gene="Rab29"
                     /gene_synonym="Rab7l1"
                     /note="RAB29, member RAS oncogene family"
                     /db_xref="GeneID:171122"
                     /db_xref="RGD:620892"
     exon            1..467
                     /gene="Rab29"
                     /gene_synonym="Rab7l1"
                     /inference="alignment:Splign:2.1.0"
     CDS             344..958
                     /gene="Rab29"
                     /gene_synonym="Rab7l1"
                     /note="rab-7-like protein 1; ras-related protein Rab-29;
                     Ras-related GTP-binding protein Rab29; RAB7, member RAS
                     oncogene family-like 1"
                     /codon_start=1
                     /product="ras-related protein Rab-7L1"
                     /protein_id="NP_598274.1"
                     /db_xref="GeneID:171122"
                     /db_xref="RGD:620892"
                     /translation="MGSRDHLFKVLVVGDAAVGKTSLVQRYSQDSFSKHYKSTVGVDF
                     ALKVLQWSDSEMVRLQLWDIAGQERFTSMTRLYYRDASACVIMFDVTNATTFSNSQRW
                     KQDLDSKLTLPSGEPVPCLLLANKSDLSPWAVSRDQIDRFSKENGFTGWTETSVKENK
                     NINEAMRVLVEKMMNNSREDIMSSSTQGNYINLQTKPSPGWTCC"
     exon            468..539
                     /gene="Rab29"
                     /gene_synonym="Rab7l1"
                     /inference="alignment:Splign:2.1.0"
     exon            540..721
                     /gene="Rab29"
                     /gene_synonym="Rab7l1"
                     /inference="alignment:Splign:2.1.0"
     exon            722..843
                     /gene="Rab29"
                     /gene_synonym="Rab7l1"
                     /inference="alignment:Splign:2.1.0"
     exon            844..1251
                     /gene="Rab29"
                     /gene_synonym="Rab7l1"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1251
                     /gene="Rab29"
                     /gene_synonym="Rab7l1"
ORIGIN      
        1 attttgtgta tgtggtcgga ggaagggccc aggtcctctg tacctctcca agcaaggtgc
       61 tggccacggt tcaactctgg cgagctgctc ggaagtccct gacaagaagg tgccaaccgc
      121 ggggggtcga gctcgtaccc gccccaccca ggctgcggcc gcgcggggag gaagcgcacc
      181 caggccgagt gcaaaagttt ccttttctgc tttccagtta gagaagcttc aaccaaccga
      241 gggtggggat gtctgacttc aactggaaga gaacccggga gccaaagggg ttaaaataag
      301 cgaattaccg ggaaaacaaa caaaaaactc cccaccacta gccatgggca gccgagatca
      361 cctgtttaaa gtgctggtgg tgggggacgc cgcggtgggt aagacgtcac tggtccagcg
      421 ctactcccag gacagcttca gcaagcacta caagtctacc gtgggagtgg attttgctct
      481 gaaggttctc cagtggtccg actcagaaat ggtgcggctc cagctgtggg atattgcagg
      541 gcaggagcgt ttcacatcca tgacacgact ctactaccga gatgcttctg cctgtgtcat
      601 catgtttgac gtcaccaatg ccactacttt cagcaacagc caacgatgga aacaggatct
      661 ggatagcaag ctcacactgc ccagtgggga gccagtgccc tgcttgctct tggccaacaa
      721 gagtgatctg tccccttggg cagtgagccg ggaccagatt gaccggttca gcaaagagaa
      781 cggttttacg ggctggacag aaacatcagt caaggagaac aaaaatatca atgaggccat
      841 gagagtcctc gtggaaaaga tgatgaacaa ttccagagaa gatataatgt cttcgtccac
      901 ccaagggaac tacatcaatc tccagaccaa accctcccca ggctggacat gctgctagct
      961 cgccttcctc tccaggtctc tcagccgttc catctcctcc tgttggctgc tcacctggcc
     1021 taaaaattct gttgaaagta tttgacctgt ctcttgccaa ctgcctagaa aggaacacca
     1081 ctgtgacttg ggaatggctg cctggaaccc agatgcattt gttgttcccc gatgttgtct
     1141 gtgacttgct gacagcccgt gtactctagt cagtgtttcc tgtgtgacaa tgatcacctc
     1201 attcttccac tgtcagatga gtttctggga aggaataaaa attagcactt g
//
