LOCUS       NM_001109979            1859 bp    mRNA    linear   ROD 17-FEB-2024
DEFINITION  Rattus norvegicus RAB1B, member RAS oncogene family (Rab1b), mRNA.
ACCESSION   NM_001109979 XM_006223612 XM_017604276
VERSION     NM_001109979.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1859)
  AUTHORS   Wilhelm,B.G., Mandad,S., Truckenbrodt,S., Krohnert,K., Schafer,C.,
            Rammner,B., Koo,S.J., Classen,G.A., Krauss,M., Haucke,V., Urlaub,H.
            and Rizzoli,S.O.
  TITLE     Composition of isolated synaptic boutons reveals the amounts of
            vesicle trafficking proteins
  JOURNAL   Science 344 (6187), 1023-1028 (2014)
   PUBMED   24876496
REFERENCE   2  (bases 1 to 1859)
  AUTHORS   Monteiro,A.C., Sumagin,R., Rankin,C.R., Leoni,G., Mina,M.J.,
            Reiter,D.M., Stehle,T., Dermody,T.S., Schaefer,S.A., Hall,R.A.,
            Nusrat,A. and Parkos,C.A.
  TITLE     JAM-A associates with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c
            and regulate epithelial barrier function
  JOURNAL   Mol Biol Cell 24 (18), 2849-2860 (2013)
   PUBMED   23885123
REFERENCE   3  (bases 1 to 1859)
  AUTHORS   Zenner,H.L., Yoshimura,S., Barr,F.A. and Crump,C.M.
  TITLE     Analysis of Rab GTPase-activating proteins indicates that Rab1a/b
            and Rab43 are important for herpes simplex virus 1 secondary
            envelopment
  JOURNAL   J Virol 85 (16), 8012-8021 (2011)
   PUBMED   21680502
REFERENCE   4  (bases 1 to 1859)
  AUTHORS   Valkova,C., Albrizio,M., Roder,I.V., Schwake,M., Betto,R.,
            Rudolf,R. and Kaether,C.
  TITLE     Sorting receptor Rer1 controls surface expression of muscle
            acetylcholine receptors by ER retention of unassembled
            alpha-subunits
  JOURNAL   Proc Natl Acad Sci U S A 108 (2), 621-625 (2011)
   PUBMED   21187406
REFERENCE   5  (bases 1 to 1859)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   6  (bases 1 to 1859)
  AUTHORS   Yoshimura,S., Gerondopoulos,A., Linford,A., Rigden,D.J. and
            Barr,F.A.
  TITLE     Family-wide characterization of the DENN domain Rab GDP-GTP
            exchange factors
  JOURNAL   J Cell Biol 191 (2), 367-381 (2010)
   PUBMED   20937701
REFERENCE   7  (bases 1 to 1859)
  AUTHORS   Cao,Z., Li,C., Higginbotham,J.N., Franklin,J.L., Tabb,D.L.,
            Graves-Deal,R., Hill,S., Cheek,K., Jerome,W.G., Lapierre,L.A.,
            Goldenring,J.R., Ham,A.J. and Coffey,R.J.
  TITLE     Use of fluorescence-activated vesicle sorting for isolation of
            Naked2-associated, basolaterally targeted exocytic vesicles for
            proteomics analysis
  JOURNAL   Mol Cell Proteomics 7 (9), 1651-1667 (2008)
   PUBMED   18504258
REFERENCE   8  (bases 1 to 1859)
  AUTHORS   Khosravi-Far,R., Lutz,R.J., Cox,A.D., Conroy,L., Bourne,J.R.,
            Sinensky,M., Balch,W.E., Buss,J.E. and Der,C.J.
  TITLE     Isoprenoid modification of rab proteins terminating in CC or CXC
            motifs
  JOURNAL   Proc Natl Acad Sci U S A 88 (14), 6264-6268 (1991)
   PUBMED   1648736
REFERENCE   9  (bases 1 to 1859)
  AUTHORS   Touchot,N., Zahraoui,A., Vielh,E. and Tavitian,A.
  TITLE     Biochemical properties of the YPT-related rab1B protein. Comparison
            with rab1A
  JOURNAL   FEBS Lett 256 (1-2), 79-84 (1989)
   PUBMED   2509243
REFERENCE   10 (bases 1 to 1859)
  AUTHORS   Vielh,E., Touchot,N., Zahraoui,A. and Tavitian,A.
  TITLE     Nucleotide sequence of a rat cDNA: rab1B, encoding a rab1-YPT
            related protein
  JOURNAL   Nucleic Acids Res 17 (4), 1770 (1989)
   PUBMED   2493636
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000045.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001109979.4.
            
            On or before Nov 27, 2020 this sequence version replaced
            XM_017604276.1, NM_001109979.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085118.1, SRR8487231.153806.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-85                JACYVU010000045.1  1185823-1185907     c
            86-158              JACYVU010000045.1  1184123-1184195     c
            159-254             JACYVU010000045.1  1183785-1183880     c
            255-350             JACYVU010000045.1  1183589-1183684     c
            351-482             JACYVU010000045.1  1179283-1179414     c
            483-1859            JACYVU010000045.1  1177816-1179192     c
FEATURES             Location/Qualifiers
     source          1..1859
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..1859
                     /gene="Rab1b"
                     /gene_synonym="Rab1bl"
                     /note="RAB1B, member RAS oncogene family"
                     /db_xref="GeneID:100126191"
                     /db_xref="RGD:1642882"
     exon            1..85
                     /gene="Rab1b"
                     /gene_synonym="Rab1bl"
                     /inference="alignment:Splign:2.1.0"
     CDS             72..677
                     /gene="Rab1b"
                     /gene_synonym="Rab1bl"
                     /EC_number="3.6.5.2"
                     /note="RAB1B-like, member RAS oncogene family"
                     /codon_start=1
                     /product="ras-related protein Rab-1B"
                     /protein_id="NP_001103449.1"
                     /db_xref="GeneID:100126191"
                     /db_xref="RGD:1642882"
                     /translation="MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVD
                     FKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQW
                     LQEIDRYASENVNKLLVGNKSDLTTKKVVDNTTAKEFADSLGVPFLETSAKNATNVEQ
                     AFMTMAAEIKKRMGPGAASGGERPNLKIDSTPVKSASGGCC"
     exon            86..158
                     /gene="Rab1b"
                     /gene_synonym="Rab1bl"
                     /inference="alignment:Splign:2.1.0"
     exon            159..254
                     /gene="Rab1b"
                     /gene_synonym="Rab1bl"
                     /inference="alignment:Splign:2.1.0"
     exon            255..350
                     /gene="Rab1b"
                     /gene_synonym="Rab1bl"
                     /inference="alignment:Splign:2.1.0"
     exon            351..482
                     /gene="Rab1b"
                     /gene_synonym="Rab1bl"
                     /inference="alignment:Splign:2.1.0"
     exon            483..1859
                     /gene="Rab1b"
                     /gene_synonym="Rab1bl"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggccaccat cttggaacgg gaggcggagc agagccgact gggagcgacc gagcgggcca
       61 ccgctgccgc catgaacccc gaatatgact acctgtttaa gctgcttttg attggtgact
      121 cgggcgtggg caagtcatgc ctgcttctgc ggtttgctga tgacacgtac acagagagct
      181 acatcagcac cattggggtg gacttcaaga ttcgaaccat tgaactggat ggcaaaacca
      241 tcaaactaca gatttgggac acagctggtc aggaacggtt caggaccatc acttccagct
      301 actatcgggg tgctcatggc atcattgtgg tgtatgacgt cactgaccag gaatcctacg
      361 ctaatgtgaa acagtggctg caggaaatag atcgctacgc cagtgagaat gtcaataaac
      421 tgctggtagg caacaagagt gacctcacca ccaagaaggt cgtggacaat accacagcca
      481 aggaatttgc agactctctg ggtgtcccct tcctggagac aagtgccaag aatgccacca
      541 atgttgaaca ggcattcatg acaatggctg cagagatcaa aaaacggatg gggccaggag
      601 cagcatctgg gggtgaacgg cccaacctga agatcgacag cactcctgtg aaatctgcta
      661 gtggtggctg ctgctagggg gggggggggg tacttggggg aggggcacct tctccagatg
      721 atgcccctgg agggggcagg aagtgcctcc ctctcctagg gcatttgagt ctgtagcttt
      781 ggggtgtcct gggctcccca tcttcctctg gcccatctgc cttctgctct gagtcccagt
      841 cctgtcaggg cccccatgga ggacatgcag aacctgtggc tggggtggtc acagggactg
      901 ctctgctgct gcctctaggt accttgaaaa gatgcccacc acgcaccttt ctctgtaatg
      961 agggctccgc tgtctgtcac tcacccccat gtatgctgca ctgggtttct cttttccctt
     1021 cttcccaata gcgagggcct ccctgcctct gctgcccctg ggtgcaggca gtagccaggg
     1081 atccagggcc ttagatccag ggtcctacat cggacctcag gacaggtgac agggctgcaa
     1141 gagcccaata gtcacctttt cctcatctct gcctcactcc acgctcccac acacggcttg
     1201 agccgtccag ctgcggttag gtcttgagca catctagggt aggtgggcgg atggctgtgc
     1261 tgggcctatg tctcaagcca gagggagcct gctcctgcct ccccctgccc tgccagagcc
     1321 aggcccgagt gctgcctgcc caccgagccc ctttgtccct gaggaaagcg gaggcggaag
     1381 gcccaccttg ccaaaggccg ggcaccagcc ttaaccctca ctctgccagc accacctccc
     1441 ttttcccagg cagcacatct ggcttgttct tcctccattc ctcagagcct gacagggcca
     1501 aacctacttc tctggggaat gtgggtgcaa tttggggttg tggggctctt cccccctccc
     1561 aactcagaat cctggcccca ccctctggca cagcttcctg tagaaagcct ttggtcttta
     1621 cctaagaagc catgtccttt gtgctgtctc ttgccagtct cgccctacaa cctgtcctcc
     1681 cctccagtgt gtatttaagt ccctgggctg cccctctggg agggagcctc ttctcccagg
     1741 ttcccctctg gtgtcatgtc aggcattttg caaggaaaag ccacttggga gaagatggaa
     1801 aaggatgaaa aaataaattt ccactggccc ttgaataagc caagggtttt tgcaaggaa
//
