LOCUS       NM_198749               3415 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Rattus norvegicus RAB15, member RAS oncogene family (Rab15), mRNA.
ACCESSION   NM_198749 XM_216743
VERSION     NM_198749.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3415)
  AUTHORS   Zografou,S., Basagiannis,D., Papafotika,A., Shirakawa,R.,
            Horiuchi,H., Auerbach,D., Fukuda,M. and Christoforidis,S.
  TITLE     A complete Rab screening reveals novel insights in Weibel-Palade
            body exocytosis
  JOURNAL   J Cell Sci 125 (Pt 20), 4780-4790 (2012)
   PUBMED   22899725
REFERENCE   2  (bases 1 to 3415)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   3  (bases 1 to 3415)
  AUTHORS   Yoshimura,S., Egerer,J., Fuchs,E., Haas,A.K. and Barr,F.A.
  TITLE     Functional dissection of Rab GTPases involved in primary cilium
            formation
  JOURNAL   J Cell Biol 178 (3), 363-369 (2007)
   PUBMED   17646400
REFERENCE   4  (bases 1 to 3415)
  AUTHORS   Strick,D.J. and Elferink,L.A.
  TITLE     Rab15 effector protein: a novel protein for receptor recycling from
            the endocytic recycling compartment
  JOURNAL   Mol Biol Cell 16 (12), 5699-5709 (2005)
   PUBMED   16195351
REFERENCE   5  (bases 1 to 3415)
  AUTHORS   Strick,D.J., Francescutti,D.M., Zhao,Y. and Elferink,L.A.
  TITLE     Mammalian suppressor of Sec4 modulates the inhibitory effect of
            Rab15 during early endocytosis
  JOURNAL   J Biol Chem 277 (36), 32722-32729 (2002)
   PUBMED   12105226
REFERENCE   6  (bases 1 to 3415)
  AUTHORS   Elferink,L.A., Anzai,K. and Scheller,R.H.
  TITLE     rab15, a novel low molecular weight GTP-binding protein
            specifically expressed in rat brain
  JOURNAL   J Biol Chem 267 (31), 22693 (1992)
   PUBMED   1429617
  REMARK    Correction to:[J Biol Chem. 1992 Mar 25;267(9):5768-75.. PMID:
            1313420]
REFERENCE   7  (bases 1 to 3415)
  AUTHORS   Elferink,L.A., Anzai,K. and Scheller,R.H.
  TITLE     rab15, a novel low molecular weight GTP-binding protein
            specifically expressed in rat brain
  JOURNAL   J Biol Chem 267 (9), 5768-5775 (1992)
   PUBMED   1313420
  REMARK    Erratum:[J Biol Chem. 1992 Nov 5;267(31):22693.. PMID: 1429617]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC094954.1.
            
            On Jun 5, 2005 this sequence version replaced NM_198749.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC094954.1, M83679.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760396 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3415
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q24"
     gene            1..3415
                     /gene="Rab15"
                     /note="RAB15, member RAS oncogene family"
                     /db_xref="GeneID:299156"
                     /db_xref="RGD:735172"
     exon            1..499
                     /gene="Rab15"
                     /inference="alignment:Splign:2.1.0"
     CDS             376..1014
                     /gene="Rab15"
                     /note="RAB15, member RAS onocogene family"
                     /codon_start=1
                     /product="ras-related protein Rab-15"
                     /protein_id="NP_942044.1"
                     /db_xref="GeneID:299156"
                     /db_xref="RGD:735172"
                     /translation="MAKQYDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVD
                     FKMKTIEVDGIKVRIQIWDTAGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIMKW
                     VSDVDEYAPEGVQKILIGNKADEEQKRQVGREQGQQLAKEYGMDFYETSACTNLNIKE
                     SFTRLTELVLQAHRKELDGLRTCASNELALAELEEDEGKTEGPANSSKTCWC"
     exon            500..560
                     /gene="Rab15"
                     /inference="alignment:Splign:2.1.0"
     exon            561..621
                     /gene="Rab15"
                     /inference="alignment:Splign:2.1.0"
     exon            622..699
                     /gene="Rab15"
                     /inference="alignment:Splign:2.1.0"
     exon            700..789
                     /gene="Rab15"
                     /inference="alignment:Splign:2.1.0"
     exon            790..855
                     /gene="Rab15"
                     /inference="alignment:Splign:2.1.0"
     exon            856..3391
                     /gene="Rab15"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgggacaccc cagggcttga aagcagagct gggacaccgc cccggacagc cacagggtcc
       61 ccgccgctcc cctcccccgc tcccgctgca gcggcggcgc aggggacgag gggagggccg
      121 gccaggggcg gcagccgcag ctgtcccctc ccacctcccc gccagcgcga gcttccccgc
      181 gccgcgctcc cgccgcagcc gcgcttcccc gcgccagcga gccagcgagc gagcgggcga
      241 ggccagcgcg ggggccgggc cgcttccttc tcgccaccgc ggcgtcctgg ggcgggctcc
      301 ggccgcgatg gcagaggctg agcggggctg agcccgcagc cgcctgcagc cttcgggccc
      361 ccttgagtcc ctgccatggc gaaacagtac gatgtgctat ttcggctact gctgatcggg
      421 gactccgggg tgggcaagac ctgcctgcta tgccgcttca ccgacaacga gttccactcc
      481 tcgcatatct ccaccatcgg tgttgacttt aagatgaaaa ccatcgaagt agacggcatc
      541 aaagtgagga tacagatttg ggacacagca gggcaggaga ggtaccagac tatcacaaaa
      601 cagtactacc ggcgagccca gggaatattt ttagtctacg acattagcag cgagcgctct
      661 tatcagcaca tcatgaagtg ggtcagtgac gtggatgagt acgccccaga aggcgtccag
      721 aagatcctca tcgggaataa ggctgacgaa gaacagaaac ggcaggtggg gagagagcaa
      781 gggcagcagc tggctaagga gtatggcatg gacttttacg aaacaagtgc ctgcaccaac
      841 cttaacatta aagagtcctt cactcgtctg accgagctgg tgctgcaggc tcacaggaaa
      901 gagctggatg gtctccgaac atgtgccagc aatgagctcg cactggccga gctggaggaa
      961 gacgaaggca aaactgaagg cccagcaaac tcttcaaaga cctgctggtg ctgagggtcc
     1021 tgtgtggaat cctccctccc ccagtcccct tccctcagga ggcccgtgga ggcagggagt
     1081 ctgggctttg tccatcactg tcctttcatt tgaagatcct gttgaaaacc agtagctgct
     1141 actcccctgc ctggccctgt gagcagcttt gctgtggtct ccgagcaacc tctgtcccca
     1201 gccctgctat cctggagtgg taacctttca acctgtttcc cagccgcagg cctgctgtga
     1261 ccccagaatg tgcttcgacc atctcaccac cccaggctcc tgggacaacg gtcaaggctg
     1321 gagtcaaagc cacttaaaga ctcctttagt gcatctcgtg ggctctctgc tttttctctt
     1381 ctttcttctc tttctccagt cccttccttc ccatgtattt tgcgtccacg tcatccacgt
     1441 ctctcctccc tagcctgtgt gtcctgctaa tgcagttcct ttcttctttc cttcctgatt
     1501 ctgcctaagg gaatggaccc aggctctgcc ccagggagga tggctcaccc tgctctgggc
     1561 tgggctgaag gctaagggtg cttcttcctc ctcccctccc tgctgcccct ttttgtgcca
     1621 tgggctgcct ccccaatggc ctgggaggta gaacattgag gtaggaagga aacactatga
     1681 ggtggtcctc aagcctggac tggcctcttc tgcctttgcc ttctgctgga gttttggcct
     1741 tgcctggctg cctacgtgcc tctgtgagga cctgagtcca gaggcaggca cagcagagaa
     1801 gaagatgaca agatggggtg gcggggatta agtcactctg ttctctacct cccatgcagc
     1861 gagtgcacag ccttttcacc cgggttcgtg gatttaaaga tgggatcaag gcctgaggac
     1921 gccagagggc aaggggatcc ccagggtcag acactgtgta gtcagctgtg agcttgagtt
     1981 agaggccaga gcggatgcga agagctggct cctagatggc agggttagga caagagtaga
     2041 gggggcttca cagaacagtg agtgctgtgg tgacagcagg gcggtcccct gtgaggacat
     2101 ttacccagac tccctggcag aggtcacaag tgatatagtc aatcactcct cgttcactga
     2161 acccagcctt cggaagttaa ggttttcccc cagagtccgt ggacaacagg ccttaaacat
     2221 ggcaagagaa gggcgggtat gggtagaata cttggtgctg ttctgccttc caggactccc
     2281 tcccccttgt tcccttattt ctaagtctaa ggctgaagct ttgccaactg ctgagtggct
     2341 actcagggag ggaaggacac ctcctccaga gttctatgct caggaagttt ctttaaccct
     2401 gtggcccaag agtagcttga aggaggcccc tcagaaaaaa aaaagaaaac gaaagcaaaa
     2461 aaccaaccct ggtagggttt gtccttacat tcccaaggtg ggaggagctc aggtaagaga
     2521 atagtcccaa gatgcacttc aaggctgggt ctggagccaa accaaaggag gagctgggct
     2581 ctgatgagca ttcactgact gaccagggat tttttcaaat ccagggcaca gcggtgatga
     2641 cagagagcct cacacctttt tagtcctcta aaaaggagat ggggatgaaa gcaatgggaa
     2701 ttccttcctg acttagcaag ccaggaagca ttcagcggga gagaacagct ctggatgtct
     2761 ggtggaggga aaaggagacc gggaatagta ggccattgtt cactaaagag agacagggtg
     2821 ttggctggaa gcctggacca tgactggctg aggtggcttc cctggggact gactcttagg
     2881 tagtagcagg tcctaggtag actcacacaa cagtgagcag agctgccttc agccagggac
     2941 ccgaggagag cttctacagg gcactggccc taacctgtgg caagtgtcac tctcttcttg
     3001 tcccagcccc tcaagcaggg acttgatttt tactaccctg gggattctgg gagggactct
     3061 gtaccatggt cacggctctg aggtacagcg acaggggact gggatatgaa gaacatctgt
     3121 gctctctctc ttctggagct cgcctcaccc taactgccag tctgggaagt ggcgtgggct
     3181 gtgtcactgg ccttgactgt tcagcaggct ttcccgcctg tctgcctgtc acccgagatc
     3241 agctccccct ggtacatcac ccgagtccca caatctcccc gtgatgggtg aactttgtgt
     3301 accgtgtctt gagttcatta tatgaattgt gagcagggtt catctatttt aaacacaaat
     3361 gtttacaaaa taaagaatct ttcaaaccat aaaaaaaaaa aaaaaaaaaa aaaaa
//
