LOCUS       NM_001107447            1564 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus RAB11 family interacting protein 2 (Rab11fip2),
            mRNA.
ACCESSION   NM_001107447 XM_001073638 XM_217660
VERSION     NM_001107447.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1564)
  AUTHORS   Royo,M., Gutierrez,Y., Fernandez-Monreal,M., Gutierrez-Eisman,S.,
            Jimenez,R., Jurado,S. and Esteban,J.A.
  TITLE     A retention-release mechanism based on RAB11FIP2 for AMPA receptor
            synaptic delivery during long-term potentiation
  JOURNAL   J Cell Sci 132 (24) (2019)
   PUBMED   31757887
  REMARK    GeneRIF: The authors propose a retention-release mechanism, where
            Rab11fip2 acts as a gate that restricts the trafficking of AMPA
            receptors, until long-term potentiation induction triggers their
            release and allows synaptic delivery.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1564)
  AUTHORS   Skjesol,A., Yurchenko,M., Bosl,K., Gravastrand,C., Nilsen,K.E.,
            Grovdal,L.M., Agliano,F., Patane,F., Lentini,G., Kim,H., Teti,G.,
            Kumar Sharma,A., Kandasamy,R.K., Sporsheim,B., Starheim,K.K.,
            Golenbock,D.T., Stenmark,H., McCaffrey,M., Espevik,T. and
            Husebye,H.
  TITLE     The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative
            bacteria by interacting with the Rab11-family interacting protein 2
  JOURNAL   PLoS Pathog 15 (3), e1007684 (2019)
   PUBMED   30883606
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1564)
  AUTHORS   Lazo,O.M., Gonzalez,A., Ascano,M., Kuruvilla,R., Couve,A. and
            Bronfman,F.C.
  TITLE     BDNF regulates Rab11-mediated recycling endosome dynamics to induce
            dendritic branching
  JOURNAL   J Neurosci 33 (14), 6112-6122 (2013)
   PUBMED   23554492
  REMARK    GeneRIF: This study provided the first evidence indicating that a
            signaling receptor regulates the activity and dynamics of
            Rab11-positive endosomes to induce a cellular response.
REFERENCE   4  (bases 1 to 1564)
  AUTHORS   Matthies,H.J., Moore,J.L., Saunders,C., Matthies,D.S.,
            Lapierre,L.A., Goldenring,J.R., Blakely,R.D. and Galli,A.
  TITLE     Rab11 supports amphetamine-stimulated norepinephrine transporter
            trafficking
  JOURNAL   J Neurosci 30 (23), 7863-7877 (2010)
   PUBMED   20534835
  REMARK    GeneRIF: Data demonstrate that AMPH leads to an increase of NET in
            endosomes of single boutons and varicosities in a Rab11-dependent
            manner.
REFERENCE   5  (bases 1 to 1564)
  AUTHORS   Chu,B.B., Ge,L., Xie,C., Zhao,Y., Miao,H.H., Wang,J., Li,B.L. and
            Song,B.L.
  TITLE     Requirement of myosin Vb.Rab11a.Rab11-FIP2 complex in
            cholesterol-regulated translocation of NPC1L1 to the cell surface
  JOURNAL   J Biol Chem 284 (33), 22481-22490 (2009)
   PUBMED   19542231
REFERENCE   6  (bases 1 to 1564)
  AUTHORS   Sugawara,K., Shibasaki,T., Mizoguchi,A., Saito,T. and Seino,S.
  TITLE     Rab11 and its effector Rip11 participate in regulation of insulin
            granule exocytosis
  JOURNAL   Genes Cells 14 (4), 445-456 (2009)
   PUBMED   19335615
REFERENCE   7  (bases 1 to 1564)
  AUTHORS   Boone,M. and Deen,P.M.
  TITLE     Physiology and pathophysiology of the vasopressin-regulated renal
            water reabsorption
  JOURNAL   Pflugers Arch 456 (6), 1005-1024 (2008)
   PUBMED   18431594
  REMARK    Review article
REFERENCE   8  (bases 1 to 1564)
  AUTHORS   Nedvetsky,P.I., Stefan,E., Frische,S., Santamaria,K., Wiesner,B.,
            Valenti,G., Hammer,J.A. 3rd, Nielsen,S., Goldenring,J.R.,
            Rosenthal,W. and Klussmann,E.
  TITLE     A Role of myosin Vb and Rab11-FIP2 in the aquaporin-2 shuttle
  JOURNAL   Traffic 8 (2), 110-123 (2007)
   PUBMED   17156409
REFERENCE   9  (bases 1 to 1564)
  AUTHORS   Jagoe,W.N., Lindsay,A.J., Read,R.J., McCoy,A.J., McCaffrey,M.W. and
            Khan,A.R.
  TITLE     Crystal structure of rab11 in complex with rab11 family interacting
            protein 2
  JOURNAL   Structure 14 (8), 1273-1283 (2006)
   PUBMED   16905101
REFERENCE   10 (bases 1 to 1564)
  AUTHORS   Ducharme,N.A., Hales,C.M., Lapierre,L.A., Ham,A.J., Oztan,A.,
            Apodaca,G. and Goldenring,J.R.
  TITLE     MARK2/EMK1/Par-1Balpha phosphorylation of Rab11-family interacting
            protein 2 is necessary for the timely establishment of polarity in
            Madin-Darby canine kidney cells
  JOURNAL   Mol Biol Cell 17 (8), 3625-3637 (2006)
   PUBMED   16775013
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Aug 28, 2009 this sequence version replaced NM_001107447.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.9601.1,
                                           SRR26360186.1897308.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-357               JAXUCZ010000001.1  269079305-269079661 c
            358-800             JAXUCZ010000001.1  269073561-269074003 c
            801-1269            JAXUCZ010000001.1  269072182-269072650 c
            1270-1315           JAXUCZ010000001.1  269049934-269049979 c
            1316-1564           JAXUCZ010000001.1  269043836-269044084 c
FEATURES             Location/Qualifiers
     source          1..1564
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q55"
     gene            1..1564
                     /gene="Rab11fip2"
                     /gene_synonym="Rab11-FIP2; RGD1308538"
                     /note="RAB11 family interacting protein 2"
                     /db_xref="GeneID:308003"
                     /db_xref="RGD:1308538"
     exon            1..357
                     /gene="Rab11fip2"
                     /gene_synonym="Rab11-FIP2; RGD1308538"
                     /inference="alignment:Splign:2.1.0"
     CDS             5..1543
                     /gene="Rab11fip2"
                     /gene_synonym="Rab11-FIP2; RGD1308538"
                     /note="RAB11 family interacting protein 2 (class I)"
                     /codon_start=1
                     /product="rab11 family-interacting protein 2"
                     /protein_id="NP_001100917.2"
                     /db_xref="GeneID:308003"
                     /db_xref="RGD:1308538"
                     /translation="MMLSEQAQKWFPTHVQVTVLQAKDLKPKGKSGTNDTYTIIQLGK
                     EKYSTSVAEKTLEPVWKEEASFELPGLLMQGNPEKYILFLIVMHRSLVGLDKFLGQVA
                     INLNDIFEDKQRRKTEWFRLESKQGKRIKNRGEIKVNIQFMRNNMTASMFDLSMKDKT
                     RSPFAKLKDKMKGRKSDGVFSDTSSAIVPSTHMPDANPEFSSGEMQMKSKPKKPFLLG
                     PQRLSSAHSMSDLTGSHLSSEKLKSSTVGPTHLLSHQINSFGVVPESGSLKSPHRRTL
                     SFDTSKLNQPGSIVDEGEHCFGRQSDPFTNVTASLPQKFATLPRKKNPFEESSEPWDS
                     STNLFSKPIEVRKESKREKREKVSLFERVTGKRDSRRSDKLNNGGSDSPCDLKSPSAF
                     NENRQDYFEYESTNPFTAKFRASTIMPSSSFHMNPTSSDDLRKIPDSNPFDATAGYRS
                     LTYEEVLQELVKHKELLRRKDTHIRELEDYIDNLLVRVMEETPSILRVPYEPSRKAGK
                     FTNS"
     exon            358..800
                     /gene="Rab11fip2"
                     /gene_synonym="Rab11-FIP2; RGD1308538"
                     /inference="alignment:Splign:2.1.0"
     exon            801..1269
                     /gene="Rab11fip2"
                     /gene_synonym="Rab11-FIP2; RGD1308538"
                     /inference="alignment:Splign:2.1.0"
     exon            1270..1315
                     /gene="Rab11fip2"
                     /gene_synonym="Rab11-FIP2; RGD1308538"
                     /inference="alignment:Splign:2.1.0"
     exon            1316..1564
                     /gene="Rab11fip2"
                     /gene_synonym="Rab11-FIP2; RGD1308538"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagaatgatg ctgtctgagc aagcccaaaa gtggtttcca acccacgtgc aggtcacagt
       61 gctccaagct aaagatctga agccaaaagg caaaagtggc accaatgaca catacaccat
      121 aattcagttg ggcaaagaga agtattctac atctgtagcg gagaaaaccc tggagccggt
      181 ctggaaggag gaggcctctt ttgagctgcc tgggttgctc atgcagggta atccggagaa
      241 atacattctt tttcttatag tgatgcacag gtccctggtg ggactggata agtttttagg
      301 gcaggtggca atcaatctca atgacatctt tgaggacaaa caaagaagga aaacagagtg
      361 gtttagatta gaatcaaaac aaggaaaaag aataaaaaac aggggtgaga taaaggtcaa
      421 tattcaattt atgaggaaca acatgacagc aagcatgttt gacttgtcaa tgaaggacaa
      481 gacgagatca ccttttgcaa aattaaaaga taagatgaaa ggcaggaaaa gcgacggggt
      541 gttttctgat acgtcctctg ccatcgttcc gagcactcac atgcctgatg ccaatcctga
      601 gttttcaagt ggtgaaatgc agatgaaatc caaaccaaaa aagccttttc ttctgggtcc
      661 tcagcggctc tcttctgccc attcgatgtc tgatttaact gggtcccact tatcttctga
      721 gaagctgaag tctagcactg taggcccaac acatcttctc agtcaccaga taaattcctt
      781 tggagttgtt ccagaaagtg gaagtctcaa gtctccacac agacgaacac taagctttga
      841 tacttctaaa ttgaaccaac ctggcagcat tgtggatgaa ggtgaacact gttttggaag
      901 acagagtgac ccatttacaa atgtgactgc ttcattaccc caaaaatttg caacactgcc
      961 aaggaagaag aatccatttg aagaaagcag tgagccatgg gacagcagca cgaatttatt
     1021 ttcaaaacca attgaagtca ggaaagaaag taagagagag aaaagggaga aggtgagcct
     1081 ctttgaaaga gtgactggga agagagatag caggagatct gacaagctga acaatggggg
     1141 atctgatagc ccatgtgact tgaaatcacc tagtgctttt aatgaaaacc ggcaggacta
     1201 ttttgaatat gagtcaacca acccgtttac agcaaaattc agggcttcaa ctataatgcc
     1261 atcttcaagt tttcatatga atccaacaag cagtgatgac ctcaggaaaa tcccggatag
     1321 caatcccttc gatgccacgg ctgggtaccg gagtctgacc tacgaagagg tgctgcagga
     1381 gctggtgaag cacaaagaac tccttcggag gaaggacacc cacatccggg agctagagga
     1441 ctacatcgac aacctccttg tcagggtgat ggaagagaca cccagcatcc tgcgagtgcc
     1501 ctatgagcca tccaggaaag ctggcaagtt taccaatagc tagtgggagt caagaggact
     1561 gttt
//
