LOCUS       NM_032617               1521 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Rattus norvegicus RAB11B, member RAS oncogene family (Rab11b),
            mRNA.
ACCESSION   NM_032617
VERSION     NM_032617.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1521)
  AUTHORS   Taoufiq,Z., Ninov,M., Villar-Briones,A., Wang,H.Y., Sasaki,T.,
            Roy,M.C., Beauchain,F., Mori,Y., Yoshida,T., Takamori,S., Jahn,R.
            and Takahashi,T.
  TITLE     Hidden proteome of synaptic vesicles in the mammalian brain
  JOURNAL   Proc Natl Acad Sci U S A 117 (52), 33586-33596 (2020)
   PUBMED   33376223
REFERENCE   2  (bases 1 to 1521)
  AUTHORS   Zhao,Z., Sagare,A.P., Ma,Q., Halliday,M.R., Kong,P., Kisler,K.,
            Winkler,E.A., Ramanathan,A., Kanekiyo,T., Bu,G., Owens,N.C.,
            Rege,S.V., Si,G., Ahuja,A., Zhu,D., Miller,C.A., Schneider,J.A.,
            Maeda,M., Maeda,T., Sugawara,T., Ichida,J.K. and Zlokovic,B.V.
  TITLE     Central role for PICALM in amyloid-beta blood-brain barrier
            transcytosis and clearance
  JOURNAL   Nat Neurosci 18 (7), 978-987 (2015)
   PUBMED   26005850
  REMARK    Erratum:[Nat Neurosci. 2024 Jan;27(1):208. doi:
            10.1038/s41593-023-01509-y.. PMID: 37985802]
REFERENCE   3  (bases 1 to 1521)
  AUTHORS   Guo,Z., Neilson,L.J., Zhong,H., Murray,P.S., Zanivan,S. and
            Zaidel-Bar,R.
  TITLE     E-cadherin interactome complexity and robustness resolved by
            quantitative proteomics
  JOURNAL   Sci Signal 7 (354), rs7 (2014)
   PUBMED   25468996
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1521)
  AUTHORS   Lindsay,A.J., Jollivet,F., Horgan,C.P., Khan,A.R., Raposo,G.,
            McCaffrey,M.W. and Goud,B.
  TITLE     Identification and characterization of multiple novel Rab-myosin Va
            interactions
  JOURNAL   Mol Biol Cell 24 (21), 3420-3434 (2013)
   PUBMED   24006491
REFERENCE   5  (bases 1 to 1521)
  AUTHORS   Hong,W.C. and Amara,S.G.
  TITLE     Differential targeting of the dopamine transporter to recycling or
            degradative pathways during amphetamine- or PKC-regulated
            endocytosis in dopamine neurons
  JOURNAL   FASEB J 27 (8), 2995-3007 (2013)
   PUBMED   23612789
  REMARK    GeneRIF: Data indicate that internalized dopamine transporter (DAT)
            colocalized with GFP-Rab11 and suggest that Rab11 plays an
            important role in the recycling of DAT following AMPH-induced DAT
            down-regulation.
REFERENCE   6  (bases 1 to 1521)
  AUTHORS   Scapin,S.M., Carneiro,F.R., Alves,A.C., Medrano,F.J.,
            Guimaraes,B.G. and Zanchin,N.I.
  TITLE     The crystal structure of the small GTPase Rab11b reveals critical
            differences relative to the Rab11a isoform
  JOURNAL   J Struct Biol 154 (3), 260-268 (2006)
   PUBMED   16545962
REFERENCE   7  (bases 1 to 1521)
  AUTHORS   Stelzl,U., Worm,U., Lalowski,M., Haenig,C., Brembeck,F.H.,
            Goehler,H., Stroedicke,M., Zenkner,M., Schoenherr,A., Koeppen,S.,
            Timm,J., Mintzlaff,S., Abraham,C., Bock,N., Kietzmann,S.,
            Goedde,A., Toksoz,E., Droege,A., Krobitsch,S., Korn,B.,
            Birchmeier,W., Lehrach,H. and Wanker,E.E.
  TITLE     A human protein-protein interaction network: a resource for
            annotating the proteome
  JOURNAL   Cell 122 (6), 957-968 (2005)
   PUBMED   16169070
REFERENCE   8  (bases 1 to 1521)
  AUTHORS   Khvotchev,M.V., Ren,M., Takamori,S., Jahn,R. and Sudhof,T.C.
  TITLE     Divergent functions of neuronal Rab11b in Ca2+-regulated versus
            constitutive exocytosis
  JOURNAL   J Neurosci 23 (33), 10531-10539 (2003)
   PUBMED   14627637
REFERENCE   9  (bases 1 to 1521)
  AUTHORS   Zhao,H., Ettala,O. and Vaananen,H.K.
  TITLE     Intracellular membrane trafficking pathways in bone-resorbing
            osteoclasts revealed by cloning and subcellular localization
            studies of small GTP-binding rab proteins
  JOURNAL   Biochem Biophys Res Commun 293 (3), 1060-1065 (2002)
   PUBMED   12051767
REFERENCE   10 (bases 1 to 1521)
  AUTHORS   Schlierf,B., Fey,G.H., Hauber,J., Hocke,G.M. and Rosorius,O.
  TITLE     Rab11b is essential for recycling of transferrin to the plasma
            membrane
  JOURNAL   Exp Cell Res 259 (1), 257-265 (2000)
   PUBMED   10942597
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC062041.1.
            
            On Dec 20, 2003 this sequence version replaced NM_032617.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC062041.1, FQ213918.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760396, SAMN06621351
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1521
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q13"
     gene            1..1521
                     /gene="Rab11b"
                     /note="RAB11B, member RAS oncogene family"
                     /db_xref="GeneID:79434"
                     /db_xref="RGD:68369"
     exon            1..90
                     /gene="Rab11b"
                     /inference="alignment:Splign:2.1.0"
     CDS             51..707
                     /gene="Rab11b"
                     /EC_number="3.6.5.2"
                     /codon_start=1
                     /product="ras-related protein Rab-11B"
                     /protein_id="NP_116006.1"
                     /db_xref="GeneID:79434"
                     /db_xref="RGD:68369"
                     /translation="MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTI
                     GVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENV
                     ERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNNLSFIETSALDSTN
                     VEEAFKNILTEIYRIVSQKQIADRAAHDESPGNNVVDISVPPTTDGQKPNKLQCCQNL
                     "
     exon            91..286
                     /gene="Rab11b"
                     /inference="alignment:Splign:2.1.0"
     exon            287..480
                     /gene="Rab11b"
                     /inference="alignment:Splign:2.1.0"
     exon            481..561
                     /gene="Rab11b"
                     /inference="alignment:Splign:2.1.0"
     exon            562..1506
                     /gene="Rab11b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtttgtggtg gggctgcgga gtcgccgatc ccgccggaag cgccaggaca atggggaccc
       61 gggacgacga gtacgattac ctattcaaag tggtgcttat tggggactca ggtgtaggta
      121 agagcaacct gctgtcacgc ttcaccagaa acgagttcaa cctagagagc aagagcacca
      181 ttggagtgga gtttgccact cgcagcattc aggtggacgg caagaccatc aaggctcaga
      241 tctgggatac tgctggccag gagcgctacc gtgccattac ctctgcgtac taccgtggtg
      301 cagtgggtgc actgctggta tatgacattg ccaagcactt gacatatgag aatgtggagc
      361 gctggctgaa ggagctgcgg gatcatgcag atagcaacat tgttatcatg ctggtgggca
      421 acaagagcga cctgcgccat cttcgggctg tgcccactga cgaggcccgt gcctttgcag
      481 aaaagaacaa cttgtccttc attgagacct cagccttgga ttccaccaat gtagaggaag
      541 cattcaagaa catcctcaca gaaatctacc gtattgtgtc acagaagcaa attgctgacc
      601 gtgcagctca tgatgagtcc cctggcaaca atgtggtgga catcagtgtg ccacccacca
      661 ccgatggaca gaaacccaat aagctgcagt gctgccagaa cctgtgactg ccctgcacct
      721 ccacccagcg tgcgtgcacg tcctcggtcc ttggccagcc cctcaccagt gtcctcccgg
      781 cccctccctt gtccctctag gacaggctgc tcccaccctc caagtgagct ccgcctgcca
      841 gcccgatggc ccaggaagag caggagtcca gtggcctctc ctgtcctgcc tgcttgagag
      901 aagctagaag ccccttgctt atgtacctgc tcttggatat tgtgggcatc ttgacagggt
      961 agggaggttg gtaggatgga caggaccagc cagaggtgag gaagatgagt ggaaggagcc
     1021 ggcttctcct gttttccatg tcagactcca gggagcaatc acctccttcc ctctctggcc
     1081 aggtgaccca gctggccctg catccccacc ccaaaccctc tctgagctga tacccgaaga
     1141 gccaggcatc aggggctgag caggtggaca ttctgggctc tgcctcctgc ctacaccacc
     1201 atagccagcg ccagcgccag cgccagcacg gcctccagca ttcccaggcc tgcgcactcc
     1261 tgctcctgcc tgtagattta tgctgggaga agacaccctt gcccccctcc ttcctcctct
     1321 gcacgcagcg ctctcctctg cccgtcccca cttctcttgt ctcgtctcct tgtctggtca
     1381 ggaacctgtc tgcaagtgaa gcaatatctc cgtgttttgt atatacaact gctcttgtag
     1441 cctttggttt tttgttattg tagagaaaca cagattcttt atacactttg taaaatttac
     1501 gccaaaaaaa aaaaaaaaaa a
//
