LOCUS       NM_031152               2262 bp    mRNA    linear   ROD 13-FEB-2025
DEFINITION  Rattus norvegicus RAB11a, member RAS oncogene family (Rab11a),
            mRNA.
ACCESSION   NM_031152
VERSION     NM_031152.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2262)
  AUTHORS   Liu,M., Li,X., Wang,J., Ji,Y., Gu,J., Wei,Y., Peng,L., Tian,C.,
            Lv,P., Wang,P., Liu,X. and Li,W.
  TITLE     Identification and validation of Rab11a in Rat orofacial
            inflammatory pain model induced by CFA
  JOURNAL   Neurochem Int 168, 105550 (2023)
   PUBMED   37268020
  REMARK    GeneRIF: Identification and validation of Rab11a in Rat orofacial
            inflammatory pain model induced by CFA.
REFERENCE   2  (bases 1 to 2262)
  AUTHORS   Taoufiq,Z., Ninov,M., Villar-Briones,A., Wang,H.Y., Sasaki,T.,
            Roy,M.C., Beauchain,F., Mori,Y., Yoshida,T., Takamori,S., Jahn,R.
            and Takahashi,T.
  TITLE     Hidden proteome of synaptic vesicles in the mammalian brain
  JOURNAL   Proc Natl Acad Sci U S A 117 (52), 33586-33596 (2020)
   PUBMED   33376223
REFERENCE   3  (bases 1 to 2262)
  AUTHORS   Wang,X., Weng,M., Ke,Y., Sapp,E., DiFiglia,M. and Li,X.
  TITLE     Kalirin Interacts with TRAPP and Regulates Rab11 and Endosomal
            Recycling
  JOURNAL   Cells 9 (5), 1132 (2020)
   PUBMED   32375403
  REMARK    GeneRIF: Kalirin Interacts with TRAPP and Regulates Rab11 and
            Endosomal Recycling.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2262)
  AUTHORS   Ji,H.H., Yao,L.L., Liu,C. and Li,X.D.
  TITLE     Regulation of Myosin-5b by Rab11a and the Rab11 family interacting
            protein 2
  JOURNAL   Biosci Rep 39 (1) (2019)
   PUBMED   30545898
  REMARK    GeneRIF: Which bridges Myo5b and the membrane-bound Rab11a.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2262)
  AUTHORS   Kokotos,A.C., Peltier,J., Davenport,E.C., Trost,M. and Cousin,M.A.
  TITLE     Activity-dependent bulk endocytosis proteome reveals a key
            presynaptic role for the monomeric GTPase Rab11
  JOURNAL   Proc Natl Acad Sci U S A 115 (43), E10177-E10186 (2018)
   PUBMED   30301801
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):2386-2388.
            doi: 10.1073/pnas.1900100116.. PMID: 30692256]
REFERENCE   6  (bases 1 to 2262)
  AUTHORS   Larkin,J.M., Coleman,H., Espinosa,A., Levenson,A., Park,M.S.,
            Woo,B., Zervoudakis,A. and Tinh,V.
  TITLE     Intracellular accumulation of pIgA-R and regulators of transcytotic
            trafficking in cholestatic rat hepatocytes
  JOURNAL   Hepatology 38 (5), 1199-1209 (2003)
   PUBMED   14578858
  REMARK    GeneRIF: pIgA-R traffics through postendosomal rab3D-, rab11a-, and
            syntaxin 2-associated compartments, implicating these proteins in
            the regulation of transcytosis.
REFERENCE   7  (bases 1 to 2262)
  AUTHORS   Scales,S.J., Hesser,B.A., Masuda,E.S. and Scheller,R.H.
  TITLE     Amisyn, a novel syntaxin-binding protein that may regulate SNARE
            complex assembly
  JOURNAL   J Biol Chem 277 (31), 28271-28279 (2002)
   PUBMED   12145319
REFERENCE   8  (bases 1 to 2262)
  AUTHORS   Prekeris,R., Klumperman,J. and Scheller,R.H.
  TITLE     A Rab11/Rip11 protein complex regulates apical membrane trafficking
            via recycling endosomes
  JOURNAL   Mol Cell 6 (6), 1437-1448 (2000)
   PUBMED   11163216
REFERENCE   9  (bases 1 to 2262)
  AUTHORS   Verges,M., Havel,R.J. and Mostov,K.E.
  TITLE     A tubular endosomal fraction from rat liver: biochemical evidence
            of receptor sorting by default
  JOURNAL   Proc Natl Acad Sci U S A 96 (18), 10146-10151 (1999)
   PUBMED   10468577
REFERENCE   10 (bases 1 to 2262)
  AUTHORS   Sakurada,K., Uchida,K., Yamaguchi,K., Aisaka,K., Ito,S., Ohmori,T.,
            Takeyama,Y., Ueda,T., Hori,Y., Ohyanagi,H. et al.
  TITLE     Molecular cloning and characterization of a ras p21-like
            GTP-binding protein (24KG) from rat liver
  JOURNAL   Biochem Biophys Res Commun 177 (3), 1224-1232 (1991)
   PUBMED   1711847
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Nov 27, 2020 this sequence version replaced NM_031152.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085727.1, SRR22399492.2174693.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676784, SAMN16676785
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-105               JAXUCZ010000008.1  74141580-74141684   c
            106-301             JAXUCZ010000008.1  74132071-74132266   c
            302-495             JAXUCZ010000008.1  74130360-74130553   c
            496-576             JAXUCZ010000008.1  74129278-74129358   c
            577-2262            JAXUCZ010000008.1  74118922-74120607   c
FEATURES             Location/Qualifiers
     source          1..2262
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..2262
                     /gene="Rab11a"
                     /note="RAB11a, member RAS oncogene family"
                     /db_xref="GeneID:81830"
                     /db_xref="RGD:619762"
     exon            1..105
                     /gene="Rab11a"
                     /inference="alignment:Splign:2.1.0"
     CDS             66..716
                     /gene="Rab11a"
                     /EC_number="3.6.5.2"
                     /note="24KG; rab-11"
                     /codon_start=1
                     /product="ras-related protein Rab-11A"
                     /protein_id="NP_112414.1"
                     /db_xref="GeneID:81830"
                     /db_xref="RGD:619762"
                     /translation="MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTI
                     GVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENV
                     ERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTN
                     VEAAFQTILTEIYRIVSQKQMSDRRENDMSPSNNVVPIHVPPTTENKPKVQCCQNI"
     exon            106..301
                     /gene="Rab11a"
                     /inference="alignment:Splign:2.1.0"
     exon            302..495
                     /gene="Rab11a"
                     /inference="alignment:Splign:2.1.0"
     exon            496..576
                     /gene="Rab11a"
                     /inference="alignment:Splign:2.1.0"
     exon            577..2262
                     /gene="Rab11a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgacgccccc tggtcccgcc gccgttacca ccgccgctcc cgcccctcag ctcctcggcc
       61 gcgccatggg cacccgcgac gacgagtacg actacctctt taaagttgtc cttattggag
      121 attctggtgt tgggaagagt aacctcctgt ctcgatttac tcggaatgag tttaatctgg
      181 aaagcaagag taccattgga gtagaatttg caacaagaag catccaggtt gatgggaaaa
      241 caataaaggc acagatatgg gacacagcag ggcaggagcg gtacagggct ataacgtctg
      301 catactatcg tggagcagta ggtgccttat tggtttatga cattgctaag catctcacat
      361 atgaaaatgt agaacgatgg ctgaaagaac tgagagatca tgctgatagt aacattgtta
      421 tcatgcttgt gggcaataag agtgatttac gtcatctcag ggcagttcct acagatgaag
      481 caagagcatt tgcagagaag aatggtttgt cgttcattga gacatctgct ctagattcta
      541 caaatgttga agctgctttt cagacaattc taacagagat ataccgcatt gtttctcaga
      601 agcaaatgtc agacagacgt gaaaatgaca tgtctccaag caacaatgtg gttcctattc
      661 atgtcccacc caccactgag aacaagccaa aggtgcagtg ctgtcagaac atctaaggcg
      721 cctctctccc ctagacggct gtgtatagtc catttcccag gtctgagatt taaatatatt
      781 tgtaattctt gtggtcactt tctgtgtttt attacttcct tacacttaag aatcttccca
      841 tgtcttaagt ctttgatttg gctttataaa atcctcaact ttgtcctgaa tgactgcagt
      901 tctttttcat gctatggctt ctctagcctt agtttaataa actgaatgtt tgaagtcctc
      961 agttattgtt tactcttcat catggaagcc tgtcactgta ggacagaata gaactcaatc
     1021 acttgaagtt cagacctcct attggtcctg attaaatcta agacaacctt agaaataagc
     1081 tattgttttg cctcagagca gcttgtaaga cattctctct aatacagtac atctgttgac
     1141 agatctaagg attgccctgt aaacataaca gcattttgag agcttgaaga tttcccattg
     1201 cggaagtcag tttctaaaat gccttaatag gtctgtgttg taaatttttt ctttagtttt
     1261 tgtaagcatc aaagattatg gggatttttt tttctggaaa agaattaata aacacaaagg
     1321 actgttatgg tttgcatagg gcgtggttat gtggtcaaag ttaccctgct gcctggtagt
     1381 ctagtagact tctgtctgag gtgtctctgt tgcagtgatc ggcagccaga gtagcttaac
     1441 cagtctcctt tcctggcagt agattgtgtg gtatttttat tgcttgtgca gtaactagct
     1501 tatgctggta atatcacatt ttgaagtgtt aattttgttt ttaaacccgt ctagtaagtg
     1561 aaatgcaacc taattttatc accatattca ccaaccagca tgggtaatta ttttaacaat
     1621 gcttatattt gagttctgca gtgtataatg gagtatagtt caattaatcc tttggtttta
     1681 gtatgtctaa agaatacaat gagaagttaa tttatgctca agtggtacca cttaaaggca
     1741 tgtgttcttt tagtatgtaa aatgaaatag taccttgaat ttaagtagaa tgtacttagg
     1801 cattgtaggg tcctgaaata gatttttcca ctacataatt gaaatcaatg gagcaactag
     1861 tttcacatta aaatgtacac actaatactt agttttactt ccttgtggat aatattaagc
     1921 acttactctg aagttttctg aaagttaact gcaaagacat tattaaggat ggtgggatac
     1981 ctgcaaaagc tatgtgggct tacatagatg actgtgtttc atggtgaaat cttctgtctt
     2041 ttgcagtgct catgatgtgt ggggagcaca gaaggcattg ctatagtcag tcatcttgtt
     2101 tttcttttgt agttatttgt tttagtgtat tggttataaa gatactgtct atttataaat
     2161 tgctactttg tattttatgc atgctctgta ttttgcctat tttttttagc tattgatttg
     2221 gagtatattc tcatcctaat aaacagttat agggggacaa tt
//
