LOCUS       NM_001002821            1097 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus RT1 class Ib, locus T18 (RT1-T18), mRNA.
ACCESSION   NM_001002821 XM_227966
VERSION     NM_001002821.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1097)
  AUTHORS   Hurt,P., Walter,L., Sudbrak,R., Klages,S., Muller,I., Shiina,T.,
            Inoko,H., Lehrach,H., Gunther,E., Reinhardt,R. and Himmelbauer,H.
  TITLE     The genomic sequence and comparative analysis of the rat major
            histocompatibility complex
  JOURNAL   Genome Res 14 (4), 631-639 (2004)
   PUBMED   15060004
REFERENCE   2  (bases 1 to 1097)
  AUTHORS   Davis,B.K., Cook,R.G., Rich,R.R. and Rodgers,J.R.
  TITLE     Hyperconservation of the putative antigen recognition site of the
            MHC class I-b molecule TL in the subfamily Murinae: evidence that
            thymus leukemia antigen is an ancient mammalian gene
  JOURNAL   J Immunol 169 (12), 6890-6899 (2002)
   PUBMED   12471122
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX883049.1.
            
            On Aug 30, 2004 this sequence version replaced XM_227966.2.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on computational evidence
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1097
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..1097
                     /gene="RT1-T18"
                     /gene_synonym="H2-T18; H2-T3; Tla"
                     /note="RT1 class Ib, locus T18"
                     /db_xref="GeneID:406194"
                     /db_xref="RGD:1303092"
     exon            1..77
                     /gene="RT1-T18"
                     /gene_synonym="H2-T18; H2-T3; Tla"
                     /inference="alignment:Splign:2.1.0"
     CDS             5..1054
                     /gene="RT1-T18"
                     /gene_synonym="H2-T18; H2-T3; Tla"
                     /note="histocompatibility 2, T region locus 18; TL
                     antigen; MHC class Ib antigen; histocompatibility 2, T
                     region locus 3; H-2 class I histocompatibility antigen,
                     TLA(B) alpha chain-like"
                     /codon_start=1
                     /product="RT1 class Ib, locus T18 precursor"
                     /protein_id="NP_001002821.1"
                     /db_xref="GeneID:406194"
                     /db_xref="RGD:1303092"
                     /translation="MGNMVPSALLLLLATSPGETQTCSGSHSLRYFYTALSRPAPGES
                     WYIAVGYVDDTQFVRFNSAGESARYKLRASWVEQEGPEYWQKETEIVTSNAQFFRGNL
                     QTMLDYYNLSHDGSHIIQVMYGCDVESDGSLLRGYEQYAYDGRDYITLNEDLKTWTAE
                     DRAAQITRLKWEQAGYAELRRTYLEGPCKDSLLRYLENRKEMLQCTDPPKAHVSHHPG
                     HEGDVTLRCWALGFYPADITLIWKKEEEELNQEMELIQTRPAGDGTFQKWAALVVPSG
                     EEQKYTCHVYHEGLPEPLTLRWEPPQSRMRTRVIVGAVLGAMAILGFMTGGAVMCMRK
                     NKGGDRDYDPAAVTM"
     exon            78..347
                     /gene="RT1-T18"
                     /gene_synonym="H2-T18; H2-T3; Tla"
                     /inference="alignment:Splign:2.1.0"
     exon            348..623
                     /gene="RT1-T18"
                     /gene_synonym="H2-T18; H2-T3; Tla"
                     /inference="alignment:Splign:2.1.0"
     exon            624..899
                     /gene="RT1-T18"
                     /gene_synonym="H2-T18; H2-T3; Tla"
                     /inference="alignment:Splign:2.1.0"
     exon            900..1013
                     /gene="RT1-T18"
                     /gene_synonym="H2-T18; H2-T3; Tla"
                     /inference="alignment:Splign:2.1.0"
     exon            1014..1097
                     /gene="RT1-T18"
                     /gene_synonym="H2-T18; H2-T3; Tla"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaggatggga aacatggtgc ccagcgccct ccttctcctc ctggcgacgt cgccaggcga
       61 gacccagacc tgctcagggt cacactctct gcggtatttc tacaccgccc tgtcccgacc
      121 tgcacccggc gagtcctggt acatcgctgt gggctacgtg gacgacacac agttcgtgcg
      181 cttcaacagc gcaggggaga gtgcgagata taagctacgt gcgtcctggg tggagcagga
      241 gggccccgag tattggcaga aggagacaga gatcgtcaca agcaatgcac agtttttccg
      301 aggaaaccta cagaccatgc ttgactacta caacctgagc cacgacggct ctcacatcat
      361 ccaggtgatg tatggctgtg acgtggaatc cgatgggagc ctcctccgcg gttatgagca
      421 gtatgcctac gatggccgag attacatcac cctcaacgaa gatcttaaga cttggacagc
      481 agaggacagg gcggcgcaga tcaccagact caagtgggag caggctggtt atgcagagct
      541 ccgcaggacc tacttagagg gcccatgcaa ggattcgctg ctcagatacc tagagaatag
      601 aaaagagatg ctgcagtgta cagatcctcc aaaggcacat gtgagccatc accccggaca
      661 tgaaggtgat gtcaccctga ggtgctgggc cctgggcttc taccctgctg acatcactct
      721 gatctggaag aaggaggagg aggaactgaa ccaagagatg gagcttatac agaccaggcc
      781 tgcaggggat gggacttttc agaagtgggc agctctggtg gtgccttctg gggaggagca
      841 gaagtacaca tgtcatgtgt accatgaggg gctacctgag cccctcaccc tgagatggga
      901 gcctcctcag tccagaatgc ggaccagggt cattgttggt gctgtccttg gtgctatggc
      961 catcttaggt tttatgactg gaggtgctgt gatgtgcatg agaaagaaca agggaggaga
     1021 cagagattat gatcctgctg ccgtcacaat gtgagggaac agttgtccct gaggtacttg
     1081 ggggggaagc tgagcca
//
