LOCUS       NM_001008840            1177 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus RT1 class I, locus CE2 (RT1-CE2), mRNA.
ACCESSION   NM_001008840 XM_579235
VERSION     NM_001008840.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1177)
  AUTHORS   Dai,K.Z., Ryan,J.C., Naper,C. and Vaage,J.T.
  TITLE     Identification of MHC Class Ib Ligands for Stimulatory and
            Inhibitory Ly49 Receptors and Induction of Potent NK Cell
            Alloresponses in Rats
  JOURNAL   J Immunol 200 (8), 2847-2859 (2018)
   PUBMED   29531166
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000020.1.
            
            On Dec 7, 2020 this sequence version replaced NM_001008840.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643288.62427.1,
                                           SRR26643291.42536.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA5760386,
                                           SAMEA5760389 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-128               JAXUCZ010000020.1  3546390-3546517     c
            129-398             JAXUCZ010000020.1  3545917-3546186     c
            399-674             JAXUCZ010000020.1  3545444-3545719     c
            675-950             JAXUCZ010000020.1  3544231-3544506     c
            951-1079            JAXUCZ010000020.1  3544008-3544136     c
            1080-1109           JAXUCZ010000020.1  3543802-3543831     c
            1110-1157           JAXUCZ010000020.1  3543529-3543576     c
            1158-1177           JAXUCZ010000020.1  3543374-3543393     c
FEATURES             Location/Qualifiers
     source          1..1177
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..1177
                     /gene="RT1-CE2"
                     /gene_synonym="RT1-C/E2"
                     /note="RT1 class I, locus CE2"
                     /db_xref="GeneID:414779"
                     /db_xref="RGD:1598235"
     exon            1..128
                     /gene="RT1-CE2"
                     /gene_synonym="RT1-C/E2"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..1162
                     /gene="RT1-CE2"
                     /gene_synonym="RT1-C/E2"
                     /note="MHC class I protein"
                     /codon_start=1
                     /product="RT1 class I, locus CE2 precursor"
                     /protein_id="NP_001008840.1"
                     /db_xref="GeneID:414779"
                     /db_xref="RGD:1598235"
                     /translation="MAPRTLLLLLAAALARTQTREGSHSLRYFKTAVSRPGLGKPLFM
                     EVGYVDDTEFVRFDSDAENPRMEPRARWMEREGPEYWDRETRIAKGNEQRFRVHLRTL
                     LGHYNQSEGGSHTFQLMYGCDLGSDGSLLRGYDHYAYDGRDYIALNEDLKTWTAADAA
                     ARITLNQWHQTGYAERRRADLEGECVESLRRYLELGKETLLRSDPPKAHVTLHPRPEG
                     DVTLRCWALGFYPADITMTWLLNGEDLSQDMELVETRPAGDGTFQKWASVVVPLGKEQ
                     NYTCLVEHEGLPEPLSQRWEPSPSTDSNMGIDVTSVLPGAVAVFVVLAIIGAVVAIVR
                     RRNTGGKGDYAPAPGRDSSQSSDVSFSDCKA"
     exon            129..398
                     /gene="RT1-CE2"
                     /gene_synonym="RT1-C/E2"
                     /inference="alignment:Splign:2.1.0"
     exon            399..674
                     /gene="RT1-CE2"
                     /gene_synonym="RT1-C/E2"
                     /inference="alignment:Splign:2.1.0"
     exon            675..950
                     /gene="RT1-CE2"
                     /gene_synonym="RT1-C/E2"
                     /inference="alignment:Splign:2.1.0"
     exon            951..1079
                     /gene="RT1-CE2"
                     /gene_synonym="RT1-C/E2"
                     /inference="alignment:Splign:2.1.0"
     exon            1080..1109
                     /gene="RT1-CE2"
                     /gene_synonym="RT1-C/E2"
                     /inference="alignment:Splign:2.1.0"
     exon            1110..1157
                     /gene="RT1-CE2"
                     /gene_synonym="RT1-C/E2"
                     /inference="alignment:Splign:2.1.0"
     exon            1158..1177
                     /gene="RT1-CE2"
                     /gene_synonym="RT1-C/E2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggcaagttc taaagtccat gcagcccgcg ggactcaggc acgtcctgga tctcaggtga
       61 ggccatggcg ccgcgcacgc tgctcttgct tctggccgca gccctggccc ggacccagac
      121 ccgggagggc tcacactcgc tgcggtattt caaaaccgcc gtgtcccggc ccggcctcgg
      181 gaagcccttg ttcatggaag tcggctacgt ggacgacacg gagttcgtgc gcttcgacag
      241 cgacgcggag aatccgagga tggagccgcg ggcgcggtgg atggagcggg aggggccgga
      301 gtattgggat cgggagacac ggatcgccaa gggaaatgag cagaggttcc gagtgcacct
      361 gaggaccctg cttggccact acaaccagag cgagggcggc tctcacacct tccagttgat
      421 gtatggctgt gacctggggt cggacgggag cctcctacgc gggtatgatc actacgccta
      481 cgatggccgc gattacatcg ccctgaacga agacctgaag acttggacgg cggcggacgc
      541 ggcggcacgg atcaccctga accagtggca tcagactggt tatgcagaga gacgcagggc
      601 cgacctggag ggcgagtgcg tggagtcact ccgcagatac ctggagctcg ggaaggagac
      661 gctgctgcgc tcagatcccc caaaggcaca tgtgaccctt caccccagac ctgaaggtga
      721 tgtcaccctg aggtgctggg ccctgggatt ctaccctgct gacatcacca tgacctggct
      781 gttgaatggg gaggacctga gccaggacat ggagcttgtg gagaccaggc ctgcagggga
      841 tggaaccttc cagaagtggg catctgtggt ggtgcctctt gggaaggagc agaattacac
      901 ttgccttgtg gagcatgagg ggctgcctga gccgctttcc cagagatggg agccttctcc
      961 atccaccgac tccaacatgg gaattgatgt tacttctgtt cttcctggag ctgtggctgt
     1021 ctttgtagtt ttggccatca ttggagctgt ggtggctatt gtgaggagga gaaacacagg
     1081 tgggaaagga gactacgccc ctgctccagg cagggacagc tcccagagct ctgatgtgtc
     1141 tttctcagat tgtaaagcat gaagacaact gcctgga
//
