LOCUS       NM_001008835            1577 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus RT1 class I, locus CE12 (RT1-CE12), mRNA.
ACCESSION   NM_001008835 XM_227986
VERSION     NM_001008835.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1577)
  AUTHORS   Dai,K.Z., Ryan,J.C., Naper,C. and Vaage,J.T.
  TITLE     Identification of MHC Class Ib Ligands for Stimulatory and
            Inhibitory Ly49 Receptors and Induction of Potent NK Cell
            Alloresponses in Rats
  JOURNAL   J Immunol 200 (8), 2847-2859 (2018)
   PUBMED   29531166
REFERENCE   2  (bases 1 to 1577)
  AUTHORS   Mauxion,F., Sobczak,J. and Kress,M.
  TITLE     Characterization of five distinct cDNA clones encoding for class I
            RT1 antigens
  JOURNAL   Immunogenetics 29 (6), 397-401 (1989)
   PUBMED   2731966
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000020.1.
            
            On Mar 11, 2021 this sequence version replaced NM_001008835.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: MG963106.1, SRR26360190.1856140.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN12840111,
                                           SAMN12840124 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-87                JAXUCZ010000020.1  3347139-3347225     c
            88-357              JAXUCZ010000020.1  3346666-3346935     c
            358-633             JAXUCZ010000020.1  3346162-3346437     c
            634-909             JAXUCZ010000020.1  3344897-3345172     c
            910-1044            JAXUCZ010000020.1  3344635-3344769     c
            1045-1077           JAXUCZ010000020.1  3344425-3344457     c
            1078-1125           JAXUCZ010000020.1  3344171-3344218     c
            1126-1577           JAXUCZ010000020.1  3343585-3344036     c
FEATURES             Location/Qualifiers
     source          1..1577
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..1577
                     /gene="RT1-CE12"
                     /gene_synonym="RT1.46"
                     /note="RT1 class I, locus CE12"
                     /db_xref="GeneID:309600"
                     /db_xref="RGD:1359103"
     exon            1..87
                     /gene="RT1-CE12"
                     /gene_synonym="RT1.46"
                     /inference="alignment:Splign:2.1.0"
     CDS             15..1130
                     /gene="RT1-CE12"
                     /gene_synonym="RT1.46"
                     /note="MHC RT44 protein; RT1 class I, CE12; MHC class I
                     antigen; RT1 class I histocompatibility antigen, AA alpha
                     chain-like"
                     /codon_start=1
                     /product="RT1 class I, locus CE12 precursor"
                     /protein_id="NP_001008835.1"
                     /db_xref="GeneID:309600"
                     /db_xref="RGD:1359103"
                     /translation="MGVTAPPLLLLLLAAALARTQTRAGSHSLRYFKTAVSRPGLGEP
                     RFMEVGYVDDTEFVRFDSDAENPRYEPRARWMEQQGPEYWERETQGAKEKEQTFRVNL
                     RTLLGYYNQSEGDSHTLQLMFGCDVGSDGRLLRGYDQFAYDGRDYIALNEDLKTWAAA
                     DVVAQMTRNKWERARYAEKRRANLEGECVESLRRFLELGKETLLRSDPPKAHVTLHPR
                     PEGDVTLRCWALGFYPADITLTWQMNGEDLTQDMELVETRPAGDGTFQKWAAVVVPLG
                     KEQNYTCLVEHEGLPEPLTLRWEPPSSTNSNMEFNVIYVVLGAISAVAISGAVIIGAV
                     LAVVRKRNTGGEGGDYTPAPDRDSCQSSNVSLPDCKA"
     exon            88..357
                     /gene="RT1-CE12"
                     /gene_synonym="RT1.46"
                     /inference="alignment:Splign:2.1.0"
     exon            358..633
                     /gene="RT1-CE12"
                     /gene_synonym="RT1.46"
                     /inference="alignment:Splign:2.1.0"
     exon            634..909
                     /gene="RT1-CE12"
                     /gene_synonym="RT1.46"
                     /inference="alignment:Splign:2.1.0"
     exon            910..1044
                     /gene="RT1-CE12"
                     /gene_synonym="RT1.46"
                     /inference="alignment:Splign:2.1.0"
     exon            1045..1077
                     /gene="RT1-CE12"
                     /gene_synonym="RT1.46"
                     /inference="alignment:Splign:2.1.0"
     exon            1078..1125
                     /gene="RT1-CE12"
                     /gene_synonym="RT1.46"
                     /inference="alignment:Splign:2.1.0"
     exon            1126..1577
                     /gene="RT1-CE12"
                     /gene_synonym="RT1.46"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtccgggatc tcggatgggg gtgactgcgc cgcccttgct gctcctgctg ctggcggccg
       61 ccttggcccg gacccagacc cgcgcgggct cacactcgct gcggtatttc aaaaccgccg
      121 tgtcccggcc cggcctcggg gagccccggt tcatggaagt cggctacgtg gacgacacgg
      181 agttcgtgcg cttcgacagt gacgcggaga atccgagata cgagccgcgg gcccggtgga
      241 tggagcagca ggggccggag tattgggagc gggagacgca gggagccaag gaaaaggagc
      301 agactttccg agtgaacctg aggacactgc ttggctacta caaccagagc gagggcgact
      361 ctcacacact ccagttgatg tttggctgtg acgtggggtc ggacgggagg ctcctccgcg
      421 ggtatgatca gttcgcctac gacggccgcg attacatcgc cctgaacgaa gacctgaaaa
      481 cgtgggcggc ggcggacgtg gtggcgcaga tgacccgaaa caagtgggag cgggctcgtt
      541 atgcagagaa acgcagggcc aatctggaag gagagtgtgt ggagtcgctc cgcagattcc
      601 tggaactcgg gaaggagacg ctgctgcgct cagatccccc aaaggcacat gtgacccttc
      661 accccagacc tgaaggtgat gtcaccctga ggtgctgggc cctgggcttc taccctgctg
      721 acatcaccct gacctggcag atgaatgggg aggacctgac ccaggacatg gagcttgtgg
      781 agaccaggcc tgcaggggat ggaaccttcc agaagtgggc agctgtggtg gtgcctcttg
      841 ggaaggagca gaattacaca tgccttgtgg agcatgaggg gctgcctgag cctctcacct
      901 tgagatggga gcctccttca tccaccaact ccaacatgga attcaatgtc atttatgttg
      961 tccttggagc catctctgct gtggccatca gtggagctgt gatcattgga gctgtgttgg
     1021 ctgttgtgag gaagagaaac acaggtgggg aaggaggaga ctacacccct gctccagaca
     1081 gggacagctg ccagagctct aatgtgtctc tcccagattg taaagcatga agacagctgc
     1141 ctgaagtgga ctgagtgaca gacgatgtgt tcaggtctct cctgtgacat ccagagccct
     1201 cagttctctt tagacaccag tgtctgaagt tccctgtgat tctatggctt cagtgtgaag
     1261 aactgtggag cccagcctgc cctgcacacc tggaccctgt ccctgcactg cctgcattcc
     1321 ctaccacagc caaccttgct ggtcctgcct ggggttgggg gctggggaca gctgcatcct
     1381 atcactcagt ggtgctttga actgcaactc ctcacttcta cactgagaat aagaatctga
     1441 gtgtgaactt gactgttcac atacttgaca cagtgttgat tgctttttaa attactggat
     1501 tgagaatact tagaggttgt tttttgtttt tgttttgttt tgttttaaat aaatggcagg
     1561 tggagaacct tccagaa
//
