LOCUS       NM_001008832            1191 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus RT1 class I, locus1 (RT1-CE1), mRNA.
ACCESSION   NM_001008832 XM_228019 XM_347318
VERSION     NM_001008832.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1191)
  AUTHORS   Dai,K.Z., Ryan,J.C., Naper,C. and Vaage,J.T.
  TITLE     Identification of MHC Class Ib Ligands for Stimulatory and
            Inhibitory Ly49 Receptors and Induction of Potent NK Cell
            Alloresponses in Rats
  JOURNAL   J Immunol 200 (8), 2847-2859 (2018)
   PUBMED   29531166
REFERENCE   2  (bases 1 to 1191)
  AUTHORS   Leong,L.Y., Le Rolle,A.F., Deverson,E.V., Powis,S.J., Larkins,A.P.,
            Vaage,J.T., Stokland,A., Lambracht-Washington,D., Rolstad,B.,
            Joly,E. and Butcher,G.W.
  TITLE     RT1-U: identification of a novel, active, class Ib alloantigen of
            the rat MHC
  JOURNAL   J Immunol 162 (2), 743-752 (1999)
   PUBMED   9916694
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX883046.1.
            
            On Dec 4, 2009 this sequence version replaced NM_001008832.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMN06680425, SAMN06680426
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-73                BX883046.1         114879-114951
            74-343              BX883046.1         115156-115425
            344-619             BX883046.1         115655-115930
            620-895             BX883046.1         116929-117204
            896-1045            BX883046.1         117332-117481
            1046-1075           BX883046.1         117644-117673
            1076-1123           BX883046.1         117880-117927
            1124-1191           BX883046.1         118063-118130
FEATURES             Location/Qualifiers
     source          1..1191
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..1191
                     /gene="RT1-CE1"
                     /gene_synonym="RT1-C/E1; RT1-CE12"
                     /note="RT1 class I, locus1"
                     /db_xref="GeneID:309603"
                     /db_xref="RGD:1595869"
     CDS             1..1128
                     /gene="RT1-CE1"
                     /gene_synonym="RT1-C/E1; RT1-CE12"
                     /note="MHC class I protein; RT1 class I, locus CE1; RT1
                     class I, CE12"
                     /codon_start=1
                     /product="RT1 class I, locus CE1 precursor"
                     /protein_id="NP_001008832.1"
                     /db_xref="GeneID:309603"
                     /db_xref="RGD:1595869"
                     /translation="MGVTAPPLLLLLLAAALARTQTRAGSHSLRYFKTAVSRPGLGEP
                     RFMEVGYVDDTEFVRFDSDAENPRYEPRVRWMERQRPEYWERETQGAKEKEQTFRVNL
                     RTLLGYYNQSEGDSHTLQLMFGCDVGSDGRLLRGYDQFAYDGRDYIALNEDLKTWAAA
                     DVVAQMTRNKWERARYAEKRRANLEGECVESLRRYLELGKETLLRSDPPKAHVTLHPR
                     PEGDVTLRCWALGFYPADITLTWQLNGEDLTQDMELVETRPAGDGTFQKWAAVVVPLG
                     KEQNYTCHMEHEGLPEPLTLRWEAPPSTNSNMEFNVIYVVLGAISAVAIIGAVIIGAV
                     LAVVRKRNTGRKGQGGKGDYAPAPDRDSCQSSNVSLPDCKA"
     exon            1..73
                     /gene="RT1-CE1"
                     /gene_synonym="RT1-C/E1; RT1-CE12"
                     /inference="alignment:Splign:2.1.0"
     exon            74..343
                     /gene="RT1-CE1"
                     /gene_synonym="RT1-C/E1; RT1-CE12"
                     /inference="alignment:Splign:2.1.0"
     exon            344..619
                     /gene="RT1-CE1"
                     /gene_synonym="RT1-C/E1; RT1-CE12"
                     /inference="alignment:Splign:2.1.0"
     exon            620..895
                     /gene="RT1-CE1"
                     /gene_synonym="RT1-C/E1; RT1-CE12"
                     /inference="alignment:Splign:2.1.0"
     exon            896..1045
                     /gene="RT1-CE1"
                     /gene_synonym="RT1-C/E1; RT1-CE12"
                     /inference="alignment:Splign:2.1.0"
     exon            1046..1075
                     /gene="RT1-CE1"
                     /gene_synonym="RT1-C/E1; RT1-CE12"
                     /inference="alignment:Splign:2.1.0"
     exon            1076..1123
                     /gene="RT1-CE1"
                     /gene_synonym="RT1-C/E1; RT1-CE12"
                     /inference="alignment:Splign:2.1.0"
     exon            1124..1191
                     /gene="RT1-CE1"
                     /gene_synonym="RT1-C/E1; RT1-CE12"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgggggtga ctgcgccgcc cttgctgctc ctgctgctgg cggccgcctt ggcccggacc
       61 cagacccgcg ctggctcaca ctcgctgcgg tatttcaaaa ccgccgtgtc ccggccgggc
      121 ctcggggagc cccggttcat ggaagtcggc tatgtggacg acacggagtt cgtgcgcttc
      181 gacagtgacg cggagaatcc gagatacgag ccgcgggtgc ggtggatgga gcggcagagg
      241 ccggagtatt gggagcggga gacgcaggga gccaaggaaa aggagcagac tttccgagtg
      301 aacctgagga ccctgcttgg ctactacaac cagagcgagg gcgactctca cacactccag
      361 ttgatgtttg gctgtgacgt ggggtcggac gggaggctcc tccgcgggta tgatcagttc
      421 gcctacgacg gccgcgatta catcgccctg aacgaagacc tgaaaacgtg ggcggcggcg
      481 gacgtggtgg cgcagatgac ccgaaacaag tgggagcggg ctcgttatgc agagaaacgc
      541 agggccaatc tggaaggaga gtgtgtggag tcgctccgca gatacctgga actcgggaag
      601 gagacgctgc tgcgctcaga tcccccaaag gcacatgtga cccttcaccc cagacctgaa
      661 ggtgatgtca ccctgaggtg ctgggccctg ggcttctacc ctgctgacat caccctgacc
      721 tggcagttga atggggagga cctgacccag gacatggagc ttgtggagac caggcctgca
      781 ggggatggaa ccttccagaa gtgggcagct gtggtggtgc ctcttgggaa ggagcagaat
      841 tacacatgcc acatggagca tgaggggctg cctgagcctc tcaccttgag atgggaggcc
      901 cctccatcca ccaactccaa catggaattc aatgtcattt atgttgtcct tggagccatc
      961 tctgctgtgg ccatcattgg agctgtgatc attggagctg tgttggctgt tgtgaggaag
     1021 agaaacacag gtaggaaagg gcagggtggg aaaggagact acgcccctgc tccagacagg
     1081 gacagctgcc agagctctaa tgtgtctctc ccagattgta aagcatgaag acagctgcct
     1141 gaagtggact gagtgacaga cgatgtgttc aggtctctcc tgtgacatcc a
//
