LOCUS       NM_001270038            1989 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus similar to Solute carrier family 23, member 2
            (Sodium-dependent vitamin C transporter 2) (RGD1565367), mRNA.
ACCESSION   NM_001270038 XM_001067886 XM_231601
VERSION     NM_001270038.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1989)
  AUTHORS   Yasujima T, Murata C, Mimura Y, Murata T, Ohkubo M, Ohta K, Inoue K
            and Yuasa H.
  TITLE     Urate transport function of rat sodium-dependent nucleobase
            transporter 1
  JOURNAL   Physiol Rep 6 (10), e13714 (2018)
   PUBMED   29845779
  REMARK    GeneRIF: Study shows that urate uptake was observed only barely in
            the everted tissue sacs of the rat small intestine, in which
            sodium-dependent nucleobase transporter 1 operates for nucleobase
            uptake. Findings suggested that urate undergoes a futile cycle, in
            which urate transported into epithelial cells is immediately
            effluxed back by urate efflux transporters, in the small intestine.
REFERENCE   2  (bases 1 to 1989)
  AUTHORS   Yamamoto S, Inoue K, Murata T, Kamigaso S, Yasujima T, Maeda JY,
            Yoshida Y, Ohta KY and Yuasa H.
  TITLE     Identification and functional characterization of the first
            nucleobase transporter in mammals: implication in the species
            difference in the intestinal absorption mechanism of nucleobases
            and their analogs between higher primates and other mammals
  JOURNAL   J Biol Chem 285 (9), 6522-6531 (2010)
   PUBMED   20042597
  REMARK    GeneRIF: identification of rat Slc23a4 as the first
            sodium-dependent nucleobase transporter (rSNBT1). The mRNA of
            rSNBT1 was expressed highly and only in the small intestine
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB511909.1.
            
            [WARNING] On Jul 13, 2023 this sequence was replaced by
            NM_001270038.2.
            
            On or before Jun 27, 2012 this sequence version replaced
            XM_231601.6, XM_001067886.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB511909.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMD00132263, SAMD00132264
                                           [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1989
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="WST"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q22"
     gene            1..1989
                     /gene="RGD1565367"
                     /gene_synonym="slc23A4; SNBT1"
                     /note="similar to Solute carrier family 23, member 2
                     (Sodium-dependent vitamin C transporter 2)"
                     /db_xref="GeneID:312226"
                     /db_xref="RGD:1565367"
     exon            1..52
                     /gene="RGD1565367"
                     /gene_synonym="slc23A4; SNBT1"
                     /inference="alignment:Splign:2.1.0"
     CDS             11..1855
                     /gene="RGD1565367"
                     /gene_synonym="slc23A4; SNBT1"
                     /note="sodium-dependent nucleobase transporter 1"
                     /codon_start=1
                     /product="solute carrier family 23 member 2-like"
                     /protein_id="NP_001256967.1"
                     /db_xref="GeneID:312226"
                     /db_xref="RGD:1565367"
                     /translation="MNSAVCSLESPNSRRGDGALSSHTEDQGKTKDRQQKDFSSSHLA
                     YGILDRPPWYLCIFLGIQHFLTALGGLVAVPLILAKDLCLQHDPLTQSYLISTIFFVS
                     GICTLLQVLLGVRLPILQGGTFAFVAPSLAMLSLPAWKCPEWTLNASLVNTSSPEFTE
                     EWQKRIRELQGAVMVASCIQMLVGFSGLIGYLMRFIGPLTIAPTISLVALPLFDSASN
                     DAGTHWGISALTIFLIVLFSQYLKNVMVPVPVYGGGKRCHISKFNLFQVFPVLLALCL
                     SWLFCFVLTVTNTFPESPTAYGYMARTDTKGSVLSQAPWFRFPYPGQWGLPTISLAGV
                     FGIIAGVISSMVESVGDYHACARLVGAPPPPKHAINRGIGIEGLGCLLAGAWGTGNGT
                     TSYSENVGALGITRVGSRMVIVAAGCVLLLMGMFGKIGAAFATIPTPVIGGMFLVMFG
                     IISAVGISNLQYVDMNSSRNLFVFGFSIFCGLAVPNWVNKNPEKLQTGILQLDQVIQV
                     LLTTGMFVGGFLGFVLDNTIPGSLEERGLLAWGEIQEDSEETPKASKVYGLPWGIGTK
                     FCTSSCTRILPFWPRIDHHGDEVGASQLTLCSQTSSGKHPWSVTETKM"
     exon            53..196
                     /gene="RGD1565367"
                     /gene_synonym="slc23A4; SNBT1"
                     /inference="alignment:Splign:2.1.0"
     exon            197..354
                     /gene="RGD1565367"
                     /gene_synonym="slc23A4; SNBT1"
                     /inference="alignment:Splign:2.1.0"
     exon            355..514
                     /gene="RGD1565367"
                     /gene_synonym="slc23A4; SNBT1"
                     /inference="alignment:Splign:2.1.0"
     exon            515..696
                     /gene="RGD1565367"
                     /gene_synonym="slc23A4; SNBT1"
                     /inference="alignment:Splign:2.1.0"
     exon            697..817
                     /gene="RGD1565367"
                     /gene_synonym="slc23A4; SNBT1"
                     /inference="alignment:Splign:2.1.0"
     exon            818..974
                     /gene="RGD1565367"
                     /gene_synonym="slc23A4; SNBT1"
                     /inference="alignment:Splign:2.1.0"
     exon            975..1228
                     /gene="RGD1565367"
                     /gene_synonym="slc23A4; SNBT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1229..1393
                     /gene="RGD1565367"
                     /gene_synonym="slc23A4; SNBT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1394..1502
                     /gene="RGD1565367"
                     /gene_synonym="slc23A4; SNBT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1503..1598
                     /gene="RGD1565367"
                     /gene_synonym="slc23A4; SNBT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1599..1989
                     /gene="RGD1565367"
                     /gene_synonym="slc23A4; SNBT1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tccagttgcc atgaactctg cagtctgcag cttggagtcc cccaacagca ggaggggtga
       61 tggtgcgctt agctcccaca ctgaagacca ggggaagaca aaggacagac agcagaagga
      121 cttcagcagc agtcacctgg cctatggcat cctggaccgc ccaccatggt acctctgcat
      181 cttcctgggg atccagcact tcctcacagc cctgggcggc ctcgtggccg tgccgctcat
      241 cctggccaag gacctgtgcc tgcagcatga ccccctgacc caaagctacc tcatcagcac
      301 cattttcttt gtctcaggca tctgcaccct cttgcaagtg cttttagggg tcaggctgcc
      361 cattcttcaa ggagggacct tcgccttcgt ggctccctct ctggccatgc tctctcttcc
      421 tgcctggaaa tgcccagagt ggactctcaa tgccagcctg gtgaacacca gctctcctga
      481 attcaccgag gagtggcaga agaggatccg agagttgcag ggcgctgtca tggtggcttc
      541 ctgcatccag atgctggtgg gtttctcggg cctcatcggc tacctcatgc gtttcattgg
      601 ccccttgacc atcgctccaa ccatttccct cgtggccctg cctctcttcg attctgctag
      661 caatgatgcc gggacccact gggggatttc tgccctgacc atcttcctca tcgtgctctt
      721 ttctcagtac ctcaaaaacg tcatggttcc tgtgcctgtt tatggaggag ggaagaggtg
      781 tcacatctcc aagttcaacc tgtttcaggt cttccctgtg ctgctagctc tgtgcctctc
      841 gtggctcttt tgcttcgtgc tcactgtcac caacaccttc cccgagtccc ccacggccta
      901 tggatacatg gcccgcacag acaccaaagg cagcgttctg agccaggccc cctggttccg
      961 cttcccttac ccaggacagt ggggcctccc caccatcagc ctggctggag tcttcggaat
     1021 catcgctgga gtgatctcct ccatggtaga gtctgtgggt gattatcacg cctgcgctcg
     1081 gctggttggg gccccgcccc ctccgaagca cgccatcaac cgtggcattg gcatcgaggg
     1141 cctcggctgc ctgctggcag gggcctgggg aaccggaaac ggtaccacgt cctacagcga
     1201 gaacgtcggt gcgctgggca tcaccagggt cgggagcagg atggtgattg tcgctgcggg
     1261 ctgtgtgctg ctcctgatgg gcatgttcgg gaagatcggg gcggcttttg ccaccatccc
     1321 tacccccgtg attggaggca tgttccttgt catgttcgga atcatcagcg ccgtggggat
     1381 ctccaacctg cagtatgtgg acatgaattc atctaggaac ctcttcgtgt ttggcttctc
     1441 aatcttctgt gggctcgccg tccctaactg ggtgaacaag aaccctgaga agctgcagac
     1501 aggaattctc cagctggacc aggtcatcca agtgctcctg accacaggca tgttcgttgg
     1561 tggatttctg ggcttcgtct tggacaacac catacctggc agcctggagg agagaggcct
     1621 tttggcatgg ggtgaaatcc aggaagattc tgaggagact ccgaaggcct caaaggtcta
     1681 tggccttccc tgggggattg gcaccaagtt ctgcacatcc tcatgtaccc gaatcctccc
     1741 cttctggccc aggatagacc accatggaga tgaggtggga gcgagccagc tcactctatg
     1801 ttcccagacc tcctctggaa agcacccatg gagtgttaca gaaaccaaga tgtgaatgga
     1861 gtggccccac cccatctcct catagccaaa ccctggcctg caaaatgcaa aactctctgt
     1921 tcacaaatag tcactcaaga gtccttccca ggaccttcca cacctgggta ccgtggtgaa
     1981 cacacagtg
//
