LOCUS       XM_225137               1513 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus similar to Cathepsin L precursor
            (Major excreted protein) (MEP) (RGD1308751), mRNA.
ACCESSION   XM_225137
VERSION     XM_225137.6
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051352.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_225137.7.
            
            On Jan 21, 2021 this sequence version replaced XM_225137.5.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1513
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..1513
                     /gene="RGD1308751"
                     /note="similar to Cathepsin L precursor (Major excreted
                     protein) (MEP); Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 20 Proteins, and 44%
                     coverage of the annotated genomic feature by RNAseq
                     alignments"
                     /db_xref="GeneID:290981"
                     /db_xref="RGD:1308751"
     CDS             1..993
                     /gene="RGD1308751"
                     /codon_start=1
                     /product="procathepsin L"
                     /protein_id="XP_225137.5"
                     /db_xref="GeneID:290981"
                     /db_xref="RGD:1308751"
                     /translation="MTPIFLLATLCLGMISAAPTHDPSFDTVWEEWKTKHGKTYNTNE
                     EGQKRAVWENNMKMINLHNEDYLKGKHGFSLEMNAFGDLTNTEFRELMTGFQSMGPKE
                     TTIFREPFLGDIPKSLDWREHGYVTPVKNQGQCGSCWAFSAVGSLEGQIFKKTGKLVS
                     LSEQNLVDCSWSYGNLGCNGGLMEFAFQYVKENRGLDTGESYAYEAQDGLCRYNPKYS
                     AANVTGFVKVPLSEDDLMSAVASVGPVSVGIDSHHQSFRFYSGGMYYEPDCSSTEMDH
                     AVLVVGYGEESDGGKYWLVKNSWGEDWGMDGYIKMAKDQNNNCGIATYAIYPTV"
ORIGIN      
        1 atgactccaa ttttcctcct ggccaccctt tgcttgggga tgatctcagc tgctccaaca
       61 catgacccca gtttcgatac tgtatgggag gaatggaaga ccaaacatgg gaaaacatac
      121 aacacgaacg aagaaggaca gaagagagca gtgtgggaga acaacatgaa gatgatcaac
      181 ctgcacaacg aggactatct gaaggggaag catggcttca gcttggagat gaatgccttt
      241 ggtgatttga ccaacacaga attcagggaa ttgatgactg gctttcaaag catgggaccc
      301 aaggagacaa ccatcttccg ggagcccttt ctgggtgata tccccaagtc tttggattgg
      361 agagagcatg gctatgtgac tcctgtgaaa aaccagggtc agtgtggctc ttgttgggct
      421 ttcagtgcag ttggttcctt agaaggacaa atattcaaga aaacgggcaa actggtatct
      481 ctgagtgaac agaacctagt ggactgctcc tggtcatatg gaaacctagg ttgtaatggt
      541 ggcttaatgg agtttgcctt ccagtatgtg aaagaaaaca gaggcctgga cacaggggag
      601 tcctatgcat atgaagcaca ggatggacta tgccggtata atcctaagta ctcggcagct
      661 aatgttacag gctttgtgaa agtcccactg agcgaagatg accttatgag tgccgtggcc
      721 agtgtggggc ctgtctcagt tggaatcgac tctcatcacc aatccttcag gttctacagt
      781 ggcggcatgt actatgagcc agactgtagc agcactgaaa tggatcatgc tgtcctggtg
      841 gttggctatg gtgaagaatc agacggcggg aagtactggc tggtcaagaa cagctggggt
      901 gaagactggg gcatggatgg ctacataaag atggccaaag accagaacaa caactgtggg
      961 attgctacgt atgccatcta ccccactgtg tgagctgctg gacaagaaga gggaaggact
     1021 gggctgcggg tgacctgcac agaggacgtt ccccttcgca gaccggcctc tgctcagtgg
     1081 ggaatggcgg ctgagtcgct gaaggtccat gctacggtgt agattctggg acattttact
     1141 ccagttaaat gcacctgcca atctgtgctg taagccgttt tgtaacagtg acttctgagt
     1201 tttcttcttc ttcttctttt tttttttttt ttttacaaga tgtacagaat ttctataaaa
     1261 cctacattga aaagactggt ggtggtgcct ccttctgtct ttgctgcagt gggtttctct
     1321 tagtgaagga gcagtggggt ggtgttctag gggaggggtg ggatgctcct tcagacttag
     1381 gttaatattc cggcttcctc ggagtccttt ccaaagttta tggactcacc atcaactatg
     1441 gtaggaagaa tgatgaaaaa tgaaaactct tgaaatttaa tccatgcaaa ctttcaaagt
     1501 ttaaatccct tgc
//
