LOCUS       NM_001106230            2166 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus glutaminyl-peptide cyclotransferase-like (Qpctl),
            mRNA.
ACCESSION   NM_001106230 XM_001066591 XM_214869
VERSION     NM_001106230.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2166)
  AUTHORS   Huang KF, Liaw SS, Huang WL, Chia CY, Lo YC, Chen YL and Wang AH.
  TITLE     Structures of human Golgi-resident glutaminyl cyclase and its
            complexes with inhibitors reveal a large loop movement upon
            inhibitor binding
  JOURNAL   J Biol Chem 286 (14), 12439-12449 (2011)
   PUBMED   21288892
REFERENCE   2  (bases 1 to 2166)
  AUTHORS   Ghosh D, Lippert D, Krokhin O, Cortens JP and Wilkins JA.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   3  (bases 1 to 2166)
  AUTHORS   Cynis H, Rahfeld JU, Stephan A, Kehlen A, Koch B, Wermann M, Demuth
            HU and Schilling S.
  TITLE     Isolation of an isoenzyme of human glutaminyl cyclase: retention in
            the Golgi complex suggests involvement in the protein maturation
            machinery
  JOURNAL   J Mol Biol 379 (5), 966-980 (2008)
   PUBMED   18486145
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473979.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001066591.1, XM_214869.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC169076.1, SRR8487226.32931.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760476, SAMN16093050
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2166
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..2166
                     /gene="Qpctl"
                     /gene_synonym="RGD1308128"
                     /note="glutaminyl-peptide cyclotransferase-like"
                     /db_xref="GeneID:292687"
                     /db_xref="RGD:1308128"
     exon            1..269
                     /gene="Qpctl"
                     /gene_synonym="RGD1308128"
                     /inference="alignment:Splign:2.1.0"
     CDS             60..1211
                     /gene="Qpctl"
                     /gene_synonym="RGD1308128"
                     /EC_number="2.3.2.5"
                     /codon_start=1
                     /product="glutaminyl-peptide cyclotransferase-like
                     protein"
                     /protein_id="NP_001099700.1"
                     /db_xref="GeneID:292687"
                     /db_xref="RGD:1308128"
                     /translation="MSPASRGRSRQRLGDRGLMKPPSLSKRRLLPRVQLLPLLLLALA
                     LGLAFYIVWNSWHPGVEEVSRSRDLRVPLIGSLSEAKLRLVVGQLDPQRLWGTFLRPL
                     LIVRPPGSPGNLQVRKFLEATLQSLSAGWHVELDPFTASTPLGPLDFGNVVATLDPGA
                     ARHLTLACHYDSKFFPPGLPPFVGATDSAVPCALLLELVQALDVMLSRIKQQAAPVTL
                     QLLFLDGEEALKEWGPKDSLYGSRHLAQIMESIPHSPGPTRIQAIELFVLLDLLGAPS
                     PIFFSHFPRTARWFQRLRSIEKRLHRLNLLQSHPQEVMYFQPGEPPGPVEDDHIPFLR
                     RGVPVLHLIAMPFPAVWHTPADTEANLHPPTVHNLSRILAVFLAEYLGL"
     exon            270..413
                     /gene="Qpctl"
                     /gene_synonym="RGD1308128"
                     /inference="alignment:Splign:2.1.0"
     exon            414..695
                     /gene="Qpctl"
                     /gene_synonym="RGD1308128"
                     /inference="alignment:Splign:2.1.0"
     exon            696..848
                     /gene="Qpctl"
                     /gene_synonym="RGD1308128"
                     /inference="alignment:Splign:2.1.0"
     exon            849..948
                     /gene="Qpctl"
                     /gene_synonym="RGD1308128"
                     /inference="alignment:Splign:2.1.0"
     exon            949..1065
                     /gene="Qpctl"
                     /gene_synonym="RGD1308128"
                     /inference="alignment:Splign:2.1.0"
     exon            1066..2166
                     /gene="Qpctl"
                     /gene_synonym="RGD1308128"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaatcttggc ctaaactcaa accaccctgc ggggggattg gtttcagggc aaagctgcca
       61 tgagtccggc cagccgcggg cggtctcggc agcggctcgg ggatcgcggc ctcatgaaac
      121 caccctcact ttccaagcgc cgtcttctgc cgcgggtgca gctcctgccc ctgctgctgc
      181 tggcgctggc cctgggcttg gctttttata tcgtctggaa tagctggcac cctggggttg
      241 aggaggtatc acggagccgg gatctgcggg tcccgctgat cggaagcctt tcagaagcca
      301 agctgcggct tgtggtaggg cagctggatc cacagcgtct ctggggaact tttctgcgtc
      361 ccttgttgat tgtacgaccc ccaggtagtc ctggcaatct ccaagtgaga aagttcctgg
      421 aggctacgtt gcagtcccta tcggcaggct ggcacgtgga actggaccca ttcacagcct
      481 caaccccctt ggggccactg gacttcggga acgtggtggc cacccttgac ccaggagctg
      541 cccgtcacct caccctcgcc tgccattatg actctaagtt cttccctcct gggttacccc
      601 cctttgtggg ggccacagat tcagccgtgc cctgtgccct gcttctggag ttagtccagg
      661 cccttgatgt catgctgagc agaatcaagc agcaggcagc accagtgacc ctgcagctgc
      721 tcttcttgga cggggaggag gcactgaagg agtggggacc aaaggactcc ctctatggtt
      781 cccggcacct agctcagatc atggagtcta taccgcacag ccctggcccc accaggatcc
      841 aggctattga gctctttgtc cttcttgacc ttctgggagc gcccagtcca atcttcttca
      901 gtcacttccc ccgcacagcc cgctggttcc aacgactgcg gagcatcgag aagcgccttc
      961 accgtctgaa cctactgcag tctcaccccc aggaagtgat gtacttccaa cccggggagc
     1021 cccctggccc tgtggaagat gaccacatcc ccttccttcg cagaggggtc ccggtgctcc
     1081 acctcattgc gatgcccttc cctgccgtgt ggcacacacc tgctgacact gaggctaacc
     1141 tccacccgcc cacggtgcac aacctgagcc gcatcctcgc cgtgttcctg gctgagtacc
     1201 tgggtctcta gcctgcagac tgataccctg aagggatctt acagctagct gtgaactggt
     1261 cacgtgcact tggagccagt gcggggcggc caggctcacc tcagatgtat gctataacca
     1321 tgtcaaagcc acggtgtttc aaggatatgc aaggaacact gagggcataa gagagccaaa
     1381 ggaaatcagg aatgaatcct ttggcctgtc ctgaagtaaa taactggaag tttccaggga
     1441 ccaatgatgt gtcatgggct ggcacttgga ccagtaccac caaccaaatg aatcctctgt
     1501 ggctaacgtt ttatgtcagt tcatttgcta ctgcacggac ccagttcaga ctctgcggcc
     1561 tctgcgtggg gatgggctca tgacttggga cagagacgaa gcctagctct gtgtcctaca
     1621 gtctgcctga ctcgggtgcc aacctcgagg gcgaaggagg actgaaggcc acagctccca
     1681 tgagaagtga cattaaatga gcttcctcac tgcaaaaggt gagatcttca gagtaaagaa
     1741 tgaaatagtt ctcaaagtac ttcacagtgg ggcctctttg caggaaggca tttcaagttg
     1801 aagctgcctc agagcatact ttgggaaata ctggctttgg caggtttgag agtgggaatg
     1861 gactggatag actgagatcc accttttgtt gtgtgtacaa ctctggtgaa aagagtttct
     1921 ttttctttct actcttgttt gtttttgata cggggtttct ctgtgtagtg ctgcctgtcc
     1981 tgaaacttca tctgtagtcc aggctggcct caaattttaa agattcacat tcctccgcct
     2041 ccagagtgct gggataaagg gcattatcac cactgcctgg ctggcctgga actttctgtg
     2101 tagaccttga acacgagaga tgtgactcca cctccactgg gatcgaaagg aagagccacc
     2161 atattc
//
