LOCUS       NM_001106447            2837 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus pygopus family PHD finger 2 (Pygo2), mRNA.
ACCESSION   NM_001106447 XM_001073224 XM_001073257 XM_227419
VERSION     NM_001106447.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2837)
  AUTHORS   van Tienen,L.M., Mieszczanek,J., Fiedler,M., Rutherford,T.J. and
            Bienz,M.
  TITLE     Constitutive scaffolding of multiple Wnt enhanceosome components by
            Legless/BCL9
  JOURNAL   Elife 6, e20882 (2017)
   PUBMED   28296634
  REMARK    Erratum:[Elife. 2017 Mar 30;6:. PMID: 28358670]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2837)
  AUTHORS   Cantu,C., Valenta,T., Hausmann,G., Vilain,N., Aguet,M. and
            Basler,K.
  TITLE     The Pygo2-H3K4me2/3 interaction is dispensable for mouse
            development and Wnt signaling-dependent transcription
  JOURNAL   Development 140 (11), 2377-2386 (2013)
   PUBMED   23637336
REFERENCE   3  (bases 1 to 2837)
  AUTHORS   Chen,Y.Y., Li,B.A., Wang,H.D., Liu,X.Y., Tan,G.W., Ma,Y.H.,
            Shen,S.H., Zhu,H.W. and Wang,Z.X.
  TITLE     The role of Pygopus 2 in rat glioma cell growth
  JOURNAL   Med Oncol 28 (2), 631-640 (2011)
   PUBMED   20361361
  REMARK    GeneRIF: Pygo2 is highly expressed in and promotes the growth of
            glioma cells by
REFERENCE   4  (bases 1 to 2837)
  AUTHORS   Gu,B., Sun,P., Yuan,Y., Moraes,R.C., Li,A., Teng,A., Agrawal,A.,
            Rheaume,C., Bilanchone,V., Veltmaat,J.M., Takemaru,K., Millar,S.,
            Lee,E.Y., Lewis,M.T., Li,B. and Dai,X.
  TITLE     Pygo2 expands mammary progenitor cells by facilitating histone H3
            K4 methylation
  JOURNAL   J Cell Biol 185 (5), 811-826 (2009)
   PUBMED   19487454
REFERENCE   5  (bases 1 to 2837)
  AUTHORS   Schwab,K.R., Patterson,L.T., Hartman,H.A., Song,N., Lang,R.A.,
            Lin,X. and Potter,S.S.
  TITLE     Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney
            development
  JOURNAL   BMC Biol 5, 15 (2007)
   PUBMED   17425782
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001106447.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ228430.1, BC169054.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-157               JAXUCZ010000002.1  177147806-177147962
            158-207             JAXUCZ010000002.1  177148359-177148408
            208-2837            JAXUCZ010000002.1  177149844-177152473
FEATURES             Location/Qualifiers
     source          1..2837
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..2837
                     /gene="Pygo2"
                     /gene_synonym="RGD1308535"
                     /note="pygopus family PHD finger 2"
                     /db_xref="GeneID:295251"
                     /db_xref="RGD:1308535"
     exon            1..157
                     /gene="Pygo2"
                     /gene_synonym="RGD1308535"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..1272
                     /gene="Pygo2"
                     /gene_synonym="RGD1308535"
                     /note="pygopus 2"
                     /codon_start=1
                     /product="pygopus homolog 2"
                     /protein_id="NP_001099917.1"
                     /db_xref="GeneID:295251"
                     /db_xref="RGD:1308535"
                     /translation="MAASAPPPPDKLEGGSGPAPPPAPPSTGRKQGKAGLQMKSPEKK
                     RRKSNTQGPAYSHLTEFAPPPTPMVDHLVASNPFEDDFGAPKMGGAGPPFLGSPVPFG
                     GFRVQGGMAGQVPPGYGTGGGGGPQPLRRQPPPFPPNPMGPAFNMPPQGPGYPPPGNM
                     NFPSQPFNQSLGQNFSPPGGQMIPGPVGGFGPMISPTMGQPPRGELGPPPLPQRFTQP
                     GAPFGPSLQRPGQGLPSLPPNTSPFPGPDPGFPGPGGEDGGKPLNPPAPTAFPQEPHS
                     GSPAAAVNGNQPSFPPSSSGRGGGTPDANSLAPPGKAGGGSGPQPPPGLVYPCGACRS
                     EVNDDQDAILCEASCQKWFHRECTGMTESAYGLLTTEASAVWACDLCLKTKEIQSVYI
                     REGMGQLVAANDG"
     exon            158..207
                     /gene="Pygo2"
                     /gene_synonym="RGD1308535"
                     /inference="alignment:Splign:2.1.0"
     exon            208..2837
                     /gene="Pygo2"
                     /gene_synonym="RGD1308535"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggcctgag gacgcctcca tcccccgccg acgctgactc gggtccccca atccatggcc
       61 gcctcggcgc cgcccccacc ggacaagctg gagggaggca gcggccccgc accacccccc
      121 gcgccgccca gcaccgggag gaagcagggc aaggccggtc tgcaaatgaa gagccctgaa
      181 aagaagcgaa gaaagtccaa tactcagggt cctgcatact cacatctgac ggagttcgct
      241 ccacccccga cccccatggt ggatcatctg gtcgcttcta acccttttga ggatgacttc
      301 ggagccccta agatgggggg tgcgggccct ccgttccttg gcagtcctgt accctttgga
      361 ggctttcgtg tacagggggg catggcaggc caggtccccc caggctatgg cactggagga
      421 ggagggggtc cccagccgct tcgtaggcag ccacctcctt ttcctcccaa ccctatgggt
      481 ccagctttta atatgcctcc tcagggccct ggctatccgc ccccaggcaa tatgaacttt
      541 cccagtcagc ccttcaacca gtctctgggc caaaacttta gtccacctgg tgggcaaatg
      601 ataccaggcc cggtgggggg atttggtccc atgatctcac ccaccatggg gcagccccct
      661 agaggcgagc tcggtcctcc tcctctcccc caacgcttta cccaaccagg agcacccttt
      721 ggtccttctc ttcagagacc tggtcaggga ctccccagcc tgcctcccaa cacaagtccc
      781 ttccctggtc cagaccctgg ttttcctggc cctggtggtg aagatggtgg aaagcccttg
      841 aatccacccg cccccactgc ttttccccag gagccccact caggctcccc agctgctgct
      901 gttaatggga atcagcccag tttcccccct agcagcagcg gtcgaggtgg gggcactcca
      961 gatgccaaca gtctggcacc tccaggcaag gcaggtggag gctcagggcc ccagcctccc
     1021 ccgggcctgg tgtacccttg cggtgcctgt cggagcgagg tgaatgatga ccaggatgcc
     1081 attttgtgtg aggcctcctg ccagaagtgg tttcaccgtg agtgcaccgg catgaccgag
     1141 agtgcctacg gcctgctgac caccgaggcc tctgccgtct gggcctgtga tctctgcctc
     1201 aagaccaagg agatccaatc cgtctacatc cgtgagggca tgggccagtt ggtggctgcc
     1261 aacgatgggt gactgtgcga tggcttgggg aagtgtacat ctccaccatg ctcttgcagg
     1321 gtgactctcg ctcctgtctt ccactggctc cccatcccca tggagcagaa gcatggctcc
     1381 tgggagcaga aaaggaactg aggcaggcag gcaggcagaa gagcctgggt tgcttgcttg
     1441 tttgtttgtt tctgggaact tgtgcactga gtacctccca agacacagga aacaagtctt
     1501 gctgagcaga gccattccta gagtccaact cgaggctgca agagaaaagg ggctggagga
     1561 agtttcagag ggcaaggatg tcctgtgcgc agatgacccc aacacccgtg cctacaatcc
     1621 ctgcatagcc ccatggctgc tgctgtagtt cttggagtca tgcgttcaag gtttcttcgc
     1681 tccctgagat agagcccctt tcttcagtcc tggaaacaaa agtggggatt tctctcttct
     1741 ctctgtccct ttgcttcccc tggacctgac ttactccatt ccttgtggag caccaaatac
     1801 cttgaaacag gagcgttcct gaccagagca attgtctgtc tggggcttca agactgtagg
     1861 taagatgctg agaagacacc ttcctcatac caaagtcact ggtcctctct cagcttctct
     1921 tgtggttttc tctcagtgac catatgtttt gccaaaaatt gggatatgtg gtctgagtga
     1981 ccagagtatt tgaagtttgg gctcccctgg aaatctggac tggaggtcta agcccctttg
     2041 tccccgcttg tctggtgcac agtgtgacag tgcttttctt cagctcctgg tactcatttt
     2101 ctctgtctct cttggggaaa tgtaccttgt acctcattcc gtccctgatg aaaggaccca
     2161 agggaggccc tgctatggct ttggggacag gctgggcagt aggaccctca aagccatgac
     2221 actatgagct gaaagaaccc gaagttttct cttacccttt tttatcctgc gatgtcatct
     2281 tgggcctggt gatccagcaa ctaggcttgg tgtattttta tttttgtacc actctctgcc
     2341 agcaatggga ttgtggcctg atcaggagac cctctcagct gctcttctct ccagctaacc
     2401 ccaatgtcca ttcctcaact gggtggggaa ggcaggcttg ggtgtggccc tcctgagaga
     2461 gtcagaggtg cccatcttga tgataaaggc taccctctgg gacgtcccat ctcagtcctc
     2521 atgcttcctg catggggaga gagaagacac tcagagttgg cagcctttga agctgaaggc
     2581 ggcaagggtg gacctgcttc ttactctgcg cccctcagct cctaagcctc tctgcttagc
     2641 tctgtgttgt gctgtggttt tgttcgcacc tgttacctgc cactactttt gtgttgtctc
     2701 catggtttgt aaaatgctcc cggggagggc ccatcccctt gttcttctct gctgctcttt
     2761 ggaagagagt gggttggcag ggatgctgtt acaggatctt tttgtacggt tggattaata
     2821 aaatgacatg aaaatcc
//
