LOCUS       NM_001191117            1743 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus pygopus family PHD finger 1 (Pygo1), mRNA.
ACCESSION   NM_001191117 XM_001079880
VERSION     NM_001191117.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1743)
  AUTHORS   Nagamachi,A., Matsui,H., Asou,H., Ozaki,Y., Aki,D., Kanai,A.,
            Takubo,K., Suda,T., Nakamura,T., Wolff,L., Honda,H. and Inaba,T.
  TITLE     Haploinsufficiency of SAMD9L, an endosome fusion facilitator,
            causes myeloid malignancies in mice mimicking human diseases with
            monosomy 7
  JOURNAL   Cancer Cell 24 (3), 305-317 (2013)
   PUBMED   24029230
REFERENCE   2  (bases 1 to 1743)
  AUTHORS   Cantu,C., Valenta,T., Hausmann,G., Vilain,N., Aguet,M. and
            Basler,K.
  TITLE     The Pygo2-H3K4me2/3 interaction is dispensable for mouse
            development and Wnt signaling-dependent transcription
  JOURNAL   Development 140 (11), 2377-2386 (2013)
   PUBMED   23637336
REFERENCE   3  (bases 1 to 1743)
  AUTHORS   Fiedler,M., Sanchez-Barrena,M.J., Nekrasov,M., Mieszczanek,J.,
            Rybin,V., Muller,J., Evans,P. and Bienz,M.
  TITLE     Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt
            signaling complex
  JOURNAL   Mol Cell 30 (4), 507-518 (2008)
   PUBMED   18498752
REFERENCE   4  (bases 1 to 1743)
  AUTHORS   Schwab,K.R., Patterson,L.T., Hartman,H.A., Song,N., Lang,R.A.,
            Lin,X. and Potter,S.S.
  TITLE     Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney
            development
  JOURNAL   BMC Biol 5, 15 (2007)
   PUBMED   17425782
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1743)
  AUTHORS   Adachi,S., Jigami,T., Yasui,T., Nakano,T., Ohwada,S., Omori,Y.,
            Sugano,S., Ohkawara,B., Shibuya,H., Nakamura,T. and Akiyama,T.
  TITLE     Role of a BCL9-related beta-catenin-binding protein, B9L, in
            tumorigenesis induced by aberrant activation of Wnt signaling
  JOURNAL   Cancer Res 64 (23), 8496-8501 (2004)
   PUBMED   15574752
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Oct 4, 2022 this sequence version replaced NM_001191117.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643297.29037.1,
                                           SRR22582424.481673.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-306               JAXUCZ010000008.1  82546866-82547171
            307-392             JAXUCZ010000008.1  82562378-82562463
            393-1743            JAXUCZ010000008.1  82564176-82565526
FEATURES             Location/Qualifiers
     source          1..1743
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..1743
                     /gene="Pygo1"
                     /note="pygopus family PHD finger 1"
                     /db_xref="GeneID:691857"
                     /db_xref="RGD:1594620"
     exon            1..306
                     /gene="Pygo1"
                     /inference="alignment:Splign:2.1.0"
     CDS             258..1511
                     /gene="Pygo1"
                     /note="pygopus 1"
                     /codon_start=1
                     /product="pygopus homolog 1"
                     /protein_id="NP_001178046.1"
                     /db_xref="GeneID:691857"
                     /db_xref="RGD:1594620"
                     /translation="MSAEQDKEPIALKRVRGGDSGLDGLGGPNIQLGSPDKKKRKAST
                     QGASFPPLSEYAPPPNPNADHLVAANPFDDSYNTISYKPLPSSNPYLSPGYPGFGGYS
                     TFRMPPHVPPRMSSPYCGPYALRNQPHPFPQNPLGMGFNRPHAFNFGPHDNSNFGNPP
                     YNNVLTQDINMPSQHFRQGSAENFSQIPPQNVGQVSNPDLASNFAPGNNSNFNSPLES
                     NHSFIPPPNSFGQAKAPLPKQDFTQGAAKTTNQNSSTHPPHLNMEDPVNQSNVELKNV
                     NRNNVVQENSRSGSAEPTNNHANGTQNKPRQPRGTADLCTTDKSRKFSLHPSRHGHSS
                     SDPVYPCGICTNEVNDDQDAILCEASCQKWFHRICTGMTETAYGLLTAEASAVWGCDT
                     CMADKDVQLMRTREAFGPPAVGSDA"
     exon            307..392
                     /gene="Pygo1"
                     /inference="alignment:Splign:2.1.0"
     exon            393..1743
                     /gene="Pygo1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggccgcggc cctgagcccg gcagaacccg gctgagcccc gcaagcgctc ggagccccga
       61 ggcctcggcc gcctcctaaa cttttcaaag tcggcccgcg gcccggccgg cctgggctcc
      121 gagctcggcc gggaggattc cagggaccag gaggaggacc cggaggacca gaaggaggac
      181 ccggaggagg aggggccgcc gcatcaaaga caccggcttc ccgcggcccg ggggcgagcc
      241 atgcgcggcg gtcggtaatg tcagcagaac aggacaagga gcccatcgcg ctgaagagag
      301 ttagaggtgg tgacagtgga ctggatgggt taggagggcc caatatacaa ctaggaagcc
      361 cagataagaa aaaacgcaag gccagcacac agggagcttc ctttcctccg ttgtctgagt
      421 acgcaccacc gccaaatcca aacgccgacc acctcgtggc tgccaatccc ttcgatgaca
      481 gctacaacac gatttcctat aagccactgc cttcatccaa cccttatctt agccctgggt
      541 atcctggatt tggaggctac agcacgttca gaatgccacc ccacgtccct ccaagaatgt
      601 cttctcccta ctgtggtccc tacgcactca ggaatcagcc acatccattt cctcagaatc
      661 ctctgggcat gggctttaac cggcctcatg cttttaactt tgggccacat gataactcga
      721 attttggaaa cccaccttat aataacgtac tgacacagga cattaacatg cccagtcagc
      781 attttagaca aggctctgct gaaaacttta gtcagattcc cccgcagaat gttggccaag
      841 tatctaaccc tgacctggca tctaattttg cccctggaaa taattcaaat tttaactctc
      901 ccttagaatc gaatcactcg tttattccac ccccaaattc gtttggtcaa gcaaaagctc
      961 cactccccaa acaagacttt acgcaagggg cagccaaaac cacgaatcag aattcttcca
     1021 ctcacccacc tcatttaaat atggaggatc cagtcaatca gagtaatgtc gagttaaaaa
     1081 atgtcaacag aaacaacgtc gttcaagaga acagccgttc gggcagcgcg gagcccacca
     1141 acaaccacgc gaatgggacc cagaacaagc cccggcagcc caggggcacg gctgacctgt
     1201 gcaccactga caaaagccgc aagttctccc tgcaccccag ccggcacggc cattcatctt
     1261 ctgaccctgt gtacccgtgt gggatttgta caaatgaagt aaacgacgat caggatgcca
     1321 ttctgtgtga ggcctcttgt cagaagtggt ttcatcgcat ctgcaccgga atgaccgaaa
     1381 cagcctatgg gctgttgaca gctgaagcat ccgcagtgtg gggttgtgac acgtgcatgg
     1441 ctgacaagga tgtccagcta atgcgcacta gagaggcctt tggtccacct gccgtgggca
     1501 gcgatgccta agcatggttg tcagctaatg tgggttcatt ttttccctgt agaacagaga
     1561 tttggtgaca tgggagttta atgtttgaca ttattttttt aaatgcacac aaaaatatta
     1621 cattttagtt cttactaaca taatgcttca ttttattgtt ttttgttgtc ttaaaatgag
     1681 attaatgtgg ggggttgctg tagagacatc tataaataaa tgttcattgt tatttatcat
     1741 aaa
//
