LOCUS       NM_001108736            2463 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus PWWP domain containing 3A, DNA repair factor
            (Pwwp3a), mRNA.
ACCESSION   NM_001108736 XM_001076641 XM_343166
VERSION     NM_001108736.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2463)
  AUTHORS   Panier,S. and Boulton,S.J.
  TITLE     Double-strand break repair: 53BP1 comes into focus
  JOURNAL   Nat Rev Mol Cell Biol 15 (1), 7-18 (2014)
   PUBMED   24326623
  REMARK    Review article
REFERENCE   2  (bases 1 to 2463)
  AUTHORS   Huen,M.S., Huang,J., Leung,J.W., Sy,S.M., Leung,K.M., Ching,Y.P.,
            Tsao,S.W. and Chen,J.
  TITLE     Regulation of chromatin architecture by the PWWP domain-containing
            DNA damage-responsive factor EXPAND1/MUM1
  JOURNAL   Mol Cell 37 (6), 854-864 (2010)
   PUBMED   20347427
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CV126168.1,
            CK603499.1, CK597826.1, CB784307.1, CO383806.1 and CK839769.1.
            
            On Oct 26, 2007 this sequence version replaced NM_001108736.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-718               CV126168.1         27-744
            719-1160            CK603499.1         253-694
            1161-1378           CK597826.1         429-646
            1379-1552           CB784307.1         246-419
            1553-1951           CO383806.1         232-630
            1952-2463           CK839769.1         1-512               c
FEATURES             Location/Qualifiers
     source          1..2463
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..2463
                     /gene="Pwwp3a"
                     /gene_synonym="Mum1"
                     /note="PWWP domain containing 3A, DNA repair factor"
                     /db_xref="GeneID:362838"
                     /db_xref="RGD:1308340"
     exon            1..28
                     /gene="Pwwp3a"
                     /gene_synonym="Mum1"
                     /inference="alignment:Splign:2.1.0"
     exon            29..135
                     /gene="Pwwp3a"
                     /gene_synonym="Mum1"
                     /inference="alignment:Splign:2.1.0"
     CDS             79..2172
                     /gene="Pwwp3a"
                     /gene_synonym="Mum1"
                     /note="mutated melanoma-associated antigen 1; PWWP
                     domain-containing protein MUM1; melanoma associated
                     antigen (mutated) 1; melanoma ubiquitous mutated protein;
                     MUM-1"
                     /codon_start=1
                     /product="PWWP domain-containing DNA repair factor 3A"
                     /protein_id="NP_001102206.2"
                     /db_xref="GeneID:362838"
                     /db_xref="RGD:1308340"
                     /translation="MTDAKYVLCRWEKRLWPAKVLARTETSAKNKRKKEFFLDVQILS
                     LKEKIQVKSSAVEALQKSHIENIAAFLASQNEVPATPLEELTYRRSLRVALDVLNERT
                     SLSPESHPVENGSTPSQKGKPDADMASQVSSAPSPSFLSEDDQAVAAQCASKRRWECS
                     PKSLSPLSASEEDLRCKVDPKTGLSESGALGTEVPAPTGDESQNGSGSQLDHGQESTT
                     KKRQRNSGEKPARRGKAESGLSKGDSVAESGGQASSCVALASPRLPSQTWEGDPCAGV
                     EGCDPVESSGNIRPLLDSERSKGRLTKRPRLDGGRNPLPRHLGTRTVGAVPSRRSCSG
                     EVTTLRRAGDSDRPEEDPMSSEESTGFKSVHSLLEEEEEEEEEEEEEEEPPRILLYHE
                     PRSFEVGMLVWLKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPKGRGITVSLRRLK
                     HFDCKEKHALLDRAKEDFAQAIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVR
                     KSIQQDVLGTRFPQLGKGDPEEPMGDSRLGQWRPCRKVLPDRSRAARDKANQKLVEYI
                     VKAKGAESHLRAILHSRKPSRWLKTFLSSNQYVTCMETYLEDEAQLDEVVEYLQGVCR
                     DMDGEMPARGSGDRIRFILDVLLPEAIICAISAVEAVDYKTAEQKYLRGPTLSYREKE
                     IFDNELLEERNRRRR"
     exon            136..221
                     /gene="Pwwp3a"
                     /gene_synonym="Mum1"
                     /inference="alignment:Splign:2.1.0"
     exon            222..292
                     /gene="Pwwp3a"
                     /gene_synonym="Mum1"
                     /inference="alignment:Splign:2.1.0"
     exon            293..1129
                     /gene="Pwwp3a"
                     /gene_synonym="Mum1"
                     /inference="alignment:Splign:2.1.0"
     exon            1130..1252
                     /gene="Pwwp3a"
                     /gene_synonym="Mum1"
                     /inference="alignment:Splign:2.1.0"
     exon            1253..1323
                     /gene="Pwwp3a"
                     /gene_synonym="Mum1"
                     /inference="alignment:Splign:2.1.0"
     exon            1324..1400
                     /gene="Pwwp3a"
                     /gene_synonym="Mum1"
                     /inference="alignment:Splign:2.1.0"
     exon            1401..1461
                     /gene="Pwwp3a"
                     /gene_synonym="Mum1"
                     /inference="alignment:Splign:2.1.0"
     exon            1462..1537
                     /gene="Pwwp3a"
                     /gene_synonym="Mum1"
                     /inference="alignment:Splign:2.1.0"
     exon            1538..1588
                     /gene="Pwwp3a"
                     /gene_synonym="Mum1"
                     /inference="alignment:Splign:2.1.0"
     exon            1589..2025
                     /gene="Pwwp3a"
                     /gene_synonym="Mum1"
                     /inference="alignment:Splign:2.1.0"
     exon            2026..2114
                     /gene="Pwwp3a"
                     /gene_synonym="Mum1"
                     /inference="alignment:Splign:2.1.0"
     exon            2115..2446
                     /gene="Pwwp3a"
                     /gene_synonym="Mum1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcggggatc tgcgcggcgg cggaggcggg acctctggca tcagtagcac cgtgagccca
       61 gacattcctc tctgagtcat gacggatgcc aagtatgtcc tctgccgatg ggagaagcga
      121 ctgtggcctg caaaggtttt ggccagaact gagacttcag caaaaaacaa gagaaaaaag
      181 gaattctttc tagatgttca aatactctca ctaaaggaaa agatccaggt taagagctca
      241 gccgtggagg cactgcagaa gtcacacatt gagaacattg ccgccttctt ggcctctcag
      301 aatgaagtcc cagctactcc tctggaggag ctgacttacc gacggtccct gcgagtggcc
      361 ctggatgtct tgaacgagag gaccagtttg agtcctgaaa gtcatccagt cgaaaatggg
      421 agcacaccat ctcagaaggg caagccagat gcagatatgg cctcgcaggt ctctagtgct
      481 ccttctccat cttttctcag tgaagatgat caggctgtgg cagcccagtg tgcatccaag
      541 aggaggtggg agtgcagtcc aaaaagcctg tcgccgttgt ctgcctcgga agaggatctc
      601 aggtgcaaag tggaccccaa gacaggcctc tcagagagtg gagccctggg gactgaagtg
      661 cctgccccca ctggggatga gtctcagaat ggctctgggt cacagctgga ccatggacag
      721 gagagcacaa ccaaaaagag acagaggaat tcgggagaga aacctgcccg gcgcggaaaa
      781 gcagagtctg gcctttccaa gggagacagt gtcgcagaga gcggaggaca ggcaagcagc
      841 tgtgtggccc tggcttcacc caggctgccc tcccaaacct gggaggggga tccatgtgct
      901 ggagtcgaag gctgtgaccc agttgagtca tccggcaaca tcaggccgct tctggactct
      961 gagagaagca aaggacgcct cacaaagagg ccacgcttgg acggaggccg gaacccactg
     1021 cccagacatc taggaaccag aactgtgggg gcagtgccct cccgtaggag ctgctctggg
     1081 gaggtcacga cgctgcgcag ggctggagac agtgacagac cagaggaaga tcctatgtct
     1141 tcagaagaat ctacagggtt caagtccgtc cactccctgc tggaggagga ggaggaggag
     1201 gaggaggagg aggaagagga ggaggaacca ccccggatcc ttctgtatca cgaaccacga
     1261 tcatttgaag taggaatgct ggtctggctt aaataccaaa aatacccatt ctggccagcc
     1321 gtggtcaaga gtgtccggcg gagggacaag aaggccagtg tgctcttcat tgagggcaac
     1381 atgaatccca agggccgagg aatcaccgtg tcgctgcgac ggctcaagca ctttgactgc
     1441 aaggaaaagc atgcactact ggacagagcc aaagaggact ttgcccaggc tattggctgg
     1501 tgtgtctcgc ttatcactga ctaccgcgtg cggctgggct gcggctcctt cgccgggtcg
     1561 ttcttggaat attacgctgc tgatatcagc tatcctgtgc gcaagtctat ccaacaggac
     1621 gtcctgggga ccaggtttcc tcagctgggc aagggggacc ctgaggagcc tatgggggac
     1681 agccggctgg gacagtggcg gccatgcagg aaggtgctgc ctgaccgctc cagggctgcc
     1741 cgggataaag ccaaccagaa gctggtggag tacatcgtga aggccaaggg tgcagagagc
     1801 cacctgcggg ctatcctgca cagccgcaag ccctcacgct ggctgaagac gttcctgagc
     1861 tccaatcagt acgtgacatg catggagacg tacctggagg atgaggcgca gctggatgag
     1921 gtggtggagt acctgcaggg cgtctgccga gacatggatg gcgagatgcc tgcgcgcggc
     1981 agcggcgacc gcatccgttt catcctggat gtgctgctgc ctgaggcgat catctgcgcc
     2041 atctcggcag tggaggcagt ggactacaag acagccgagc agaagtacct ccgtggcccc
     2101 acactcagct accgggaaaa ggaaatcttt gacaatgaac tcctggagga gaggaaccgt
     2161 cgccgtcgct gatgccgtag tctccacctg gccagcaccg tgtctgtggc ctgccagagg
     2221 cctgtgagaa tgtgctagaa gcaagaggcc tagtaatgtg ctgactttga tctgtgcatg
     2281 ggttctgcgt cttcagccct gagcctggga gatcagaggc catcttcaca ctagaagact
     2341 gctgcatcta tgaacagctg cttctggaag tttctgtgtg tgtacgcgtg tatgtttggt
     2401 tttatttttt taattattat tttgtttata aatgcgtttg aatgcaaaaa aaaaaaaaaa
     2461 aaa
//
