LOCUS       NM_001191877            2056 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus PWP1 homolog, endonuclein (Pwp1), mRNA.
ACCESSION   NM_001191877 XM_343186
VERSION     NM_001191877.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Liu,Y., Mattila,J., Ventela,S., Yadav,L., Zhang,W., Lamichane,N.,
            Sundstrom,J., Kauko,O., Grenman,R., Varjosalo,M., Westermarck,J.
            and Hietakangas,V.
  TITLE     PWP1 Mediates Nutrient-Dependent Growth Control through Nucleolar
            Regulation of Ribosomal Gene Expression
  JOURNAL   Dev Cell 43 (2), 240-252 (2017)
   PUBMED   29065309
REFERENCE   2  (bases 1 to 2056)
  AUTHORS   Shen,J., Jia,W., Yu,Y., Chen,J., Cao,X., Du,Y., Zhang,X., Zhu,S.,
            Chen,W., Xi,J., Wei,T., Wang,G., Yuan,D., Duan,T., Jiang,C. and
            Kang,J.
  TITLE     Pwp1 is required for the differentiation potential of mouse
            embryonic stem cells through regulating Stat3 signaling
  JOURNAL   Stem Cells 33 (3), 661-673 (2015)
   PUBMED   25335925
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from JAXUCZ010000007.1.
            
            On Jul 17, 2010 this sequence version replaced XM_343186.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643297.24580.1,
                                           SRR26643292.28789.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-131               JAXUCZ010000007.1  19886333-19886463   c
            132-190             JAXUCZ010000007.1  19884159-19884217   c
            191-375             JAXUCZ010000007.1  19883849-19884033   c
            376-558             JAXUCZ010000007.1  19882042-19882224   c
            559-669             JAXUCZ010000007.1  19879996-19880106   c
            670-800             JAXUCZ010000007.1  19879220-19879350   c
            801-862             JAXUCZ010000007.1  19878626-19878687   c
            863-959             JAXUCZ010000007.1  19876520-19876616   c
            960-1021            JAXUCZ010000007.1  19875734-19875795   c
            1022-1133           JAXUCZ010000007.1  19874108-19874219   c
            1134-1224           JAXUCZ010000007.1  19872986-19873076   c
            1225-1346           JAXUCZ010000007.1  19872769-19872890   c
            1347-1452           JAXUCZ010000007.1  19871791-19871896   c
            1453-2056           JAXUCZ010000007.1  19870465-19871068   c
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q13"
     gene            1..2056
                     /gene="Pwp1"
                     /gene_synonym="RGD1310705"
                     /note="PWP1 homolog, endonuclein"
                     /db_xref="GeneID:362856"
                     /db_xref="RGD:1310705"
     exon            1..131
                     /gene="Pwp1"
                     /gene_synonym="RGD1310705"
                     /inference="alignment:Splign:2.1.0"
     CDS             60..1562
                     /gene="Pwp1"
                     /gene_synonym="RGD1310705"
                     /codon_start=1
                     /product="periodic tryptophan protein 1 homolog"
                     /protein_id="NP_001178806.1"
                     /db_xref="GeneID:362856"
                     /db_xref="RGD:1310705"
                     /translation="MNRSRQVTCVAWVRRGVAKETPDKVELSKEEVKRLIAEAKEKLQ
                     EEGGSEEEEVGSPSEDGMQRARVQARPTEPLEDGDPQDDRTLDDDELAEYDLDNYDQE
                     DNPDAETIGESLLGLTVYGSNDQDPYVTLKDTEQYEHEDFLIKPTDNLIVCGRAEQEQ
                     CNLEVHVYNQEEESFYVHHDILLSAYPLSVEWLNFDPSPDAATGNYIAVGNMTPVIEV
                     WDLDIVDSLEPVFTLGSKLSKKKKKKGKKSSSAEGHTDAVLDLSWNKTVRNVLASASA
                     DSTVILWDLSVGKPAARLTAHTDKVQTLQFHPFEAQTLISGSYDKSVALYDCRDPSQN
                     HRLWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDARSDKPIFTLNAHNDEISGLDL
                     SSQIKGCLVTASADKFVKIWDILGERPSLIHSRDMKMGVLFCSSCCPDLPFVYAFGGQ
                     KEGLRVWDISTVSSVNEAFGRRERLAIGSTKGLSVSDPCRSGSPQTPMES"
     exon            132..190
                     /gene="Pwp1"
                     /gene_synonym="RGD1310705"
                     /inference="alignment:Splign:2.1.0"
     exon            191..375
                     /gene="Pwp1"
                     /gene_synonym="RGD1310705"
                     /inference="alignment:Splign:2.1.0"
     exon            376..558
                     /gene="Pwp1"
                     /gene_synonym="RGD1310705"
                     /inference="alignment:Splign:2.1.0"
     exon            559..669
                     /gene="Pwp1"
                     /gene_synonym="RGD1310705"
                     /inference="alignment:Splign:2.1.0"
     exon            670..800
                     /gene="Pwp1"
                     /gene_synonym="RGD1310705"
                     /inference="alignment:Splign:2.1.0"
     exon            801..862
                     /gene="Pwp1"
                     /gene_synonym="RGD1310705"
                     /inference="alignment:Splign:2.1.0"
     exon            863..959
                     /gene="Pwp1"
                     /gene_synonym="RGD1310705"
                     /inference="alignment:Splign:2.1.0"
     exon            960..1021
                     /gene="Pwp1"
                     /gene_synonym="RGD1310705"
                     /inference="alignment:Splign:2.1.0"
     exon            1022..1133
                     /gene="Pwp1"
                     /gene_synonym="RGD1310705"
                     /inference="alignment:Splign:2.1.0"
     exon            1134..1224
                     /gene="Pwp1"
                     /gene_synonym="RGD1310705"
                     /inference="alignment:Splign:2.1.0"
     exon            1225..1346
                     /gene="Pwp1"
                     /gene_synonym="RGD1310705"
                     /inference="alignment:Splign:2.1.0"
     exon            1347..1452
                     /gene="Pwp1"
                     /gene_synonym="RGD1310705"
                     /inference="alignment:Splign:2.1.0"
     exon            1453..2056
                     /gene="Pwp1"
                     /gene_synonym="RGD1310705"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctcatagtc tctcccagcg accaggtgtc ttgttcgcgc tgggttcaag cggaacatca
       61 tgaaccgcag ccgccaagtg acctgcgtgg cctgggtccg ccgcggcgtg gccaaagaga
      121 cgccagacaa ggtagagcta agtaaagagg aagtgaaacg tctcattgct gaagcaaaag
      181 aaaagttaca agaggagggt gggagtgagg aagaggaggt aggcagtcct tcagaagatg
      241 gcatgcagag agcccgggtc caggcccggc ctacggagcc gctggaggat ggggatccac
      301 aagacgaccg tacactggac gacgatgagc tggcggagta cgacttagat aactatgacc
      361 aagaggacaa cccagatgct gagaccattg gagaatctct gttggggctt acggtctatg
      421 gcagtaacga tcaggatcca tacgtcaccc tcaaagacac ggaacagtac gagcacgaag
      481 acttcttgat taagccgacc gacaacctca tcgtctgtgg ccgtgcagaa caagagcagt
      541 gtaacttaga ggtgcacgtg tacaatcaag aagaggagtc tttctatgtc caccatgaca
      601 tactcctgtc tgcatatcct ctaagtgtgg aatggctgaa ttttgatcct agcccagatg
      661 cggctactgg aaattacatt gctgtgggaa acatgacccc tgtcattgag gtgtgggacc
      721 tggatatcgt ggactctcta gaaccagtct tcacactggg aagcaagctt tcaaaaaaga
      781 agaagaagaa agggaaaaag agttcgtcag cagaaggaca tactgatgct gtccttgacc
      841 tttcctggaa taagacagtc agaaacgtgc tggcgagtgc atcagcagac agcactgtaa
      901 tcctgtggga tctgtctgtg gggaagccag cggccaggct tactgcacat acagacaagg
      961 ttcagactct gcagtttcat ccatttgaag cacagactct gatttctggg tcctatgaca
     1021 aatccgtggc tctgtacgac tgcagagacc ccagccagaa ccaccgtctg tggaggttta
     1081 gtgggcagat cgagagagtg acctggaacc acttctcacc gtgccatttc ttggccagta
     1141 cagatgatgg ctttgtatat aatctggatg cgcgctcaga taagccgatt tttacactta
     1201 atgcacacaa cgatgaaatc tctggtcttg atctgagcag tcagatcaaa ggctgccttg
     1261 tgaccgcttc agcagacaaa tttgtgaaga tctgggacat cttaggagag aggccaagtc
     1321 tcattcattc tagagacatg aagatgggag ttctcttttg ttcttcatgc tgccctgatt
     1381 tgccgtttgt ttacgccttt ggaggacaga aagaagggct tcgggtttgg gacataagca
     1441 ctgtgtcttc agtaaacgaa gcgtttggaa gacgggagag actggccatt ggcagcacaa
     1501 aaggtttatc tgttagtgac ccctgtagga gcgggagccc acagacacca atggagtcct
     1561 gacaaagatc agttcctggt gtgcttacct tagctcggag ttttaaaaac tggcctaaaa
     1621 ctgttcacat gtatctgcag ccacagatga acaaaactcc gttcctgttg ccattcctct
     1681 ctgcagcttt ggtggcagtc cacagccttt gggctgcctt caactggata ctgtacagtg
     1741 ttcttgcatt tcttggaaat aaaagttttt ttttttttta aatgattcct taaacaggcc
     1801 atctgagtag gaactgtagg tttataaaat acatggtaac tgaagtttct gagatgggac
     1861 ttgctctgtt agccaggctg atgtggctgg tgcttgtccc agcgctaggg aggagagaga
     1921 tgtgtagatt tcctaagaca tgtggccagc cagccagcct gctcagggac ccacctgcct
     1981 ccatcgtccc aggcgctgat tacccatatg catggtaggt tctagaattg aattcaggcc
     2041 ctcagtcttg caagtt
//
