LOCUS       NM_033099               5446 bp    mRNA    linear   ROD 02-APR-2024
DEFINITION  Rattus norvegicus protein tyrosine phosphatase, receptor type, V
            (Ptprv), mRNA.
ACCESSION   NM_033099
VERSION     NM_033099.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5446)
  AUTHORS   Flister,M.J., Hoffman,M.J., Reddy,P., Jacob,H.J. and Moreno,C.
  TITLE     Congenic mapping and sequence analysis of the Renin locus
  JOURNAL   Hypertension 61 (4), 850-856 (2013)
   PUBMED   23460292
REFERENCE   2  (bases 1 to 5446)
  AUTHORS   Lathrop,W., Jordan,J., Eustice,D. and Chen,D.
  TITLE     Rat osteotesticular phosphatase gene (Esp): genomic structure and
            chromosome location
  JOURNAL   Mamm Genome 10 (4), 366-370 (1999)
   PUBMED   10087294
REFERENCE   3  (bases 1 to 5446)
  AUTHORS   Mauro,L.J., Olmsted,E.A., Davis,A.R. and Dixon,J.E.
  TITLE     Parathyroid hormone regulates the expression of the receptor
            protein tyrosine phosphatase, OST-PTP, in rat osteoblast-like cells
  JOURNAL   Endocrinology 137 (3), 925-933 (1996)
   PUBMED   8603605
REFERENCE   4  (bases 1 to 5446)
  AUTHORS   Mauro,L.J., Olmsted,E.A., Skrobacz,B.M., Mourey,R.J., Davis,A.R.
            and Dixon,J.E.
  TITLE     Identification of a hormonally regulated protein tyrosine
            phosphatase associated with bone and testicular differentiation
  JOURNAL   J Biol Chem 269 (48), 30659-30667 (1994)
   PUBMED   7527035
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from L36884.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: L36884.1, SRR8487227.65596.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132263 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..5446
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q13"
     gene            1..5446
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /note="protein tyrosine phosphatase, receptor type, V"
                     /db_xref="GeneID:64576"
                     /db_xref="RGD:621123"
     exon            1..133
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            134..193
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            194..261
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     CDS             205..5340
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /EC_number="3.1.3.48"
                     /note="Osteotesticular phosphatase; receptor-type
                     tyrosine-protein phosphatase V; OST-PTP; ES cell
                     phosphatase; osteotesticular protein-tyrosine phosphatase;
                     embryonic stem cell protein-tyrosine phosphatase; R-PTP-V;
                     protein tyrosine phosphatase receptor type W"
                     /codon_start=1
                     /product="receptor-type tyrosine-protein phosphatase V
                     precursor"
                     /protein_id="NP_149090.1"
                     /db_xref="GeneID:64576"
                     /db_xref="RGD:621123"
                     /translation="MRPLILLAALLWLQGFLAEDDACSSLEGSPDRQGGGPLLSVNVS
                     SHGKSTSLFLSWVAAELGGFDYALSLRSVNSSGSPEGQQLQAHTNESGFEFHGLVPGS
                     RYQLKLTVLRPCWQNVTITLTARTAPTVVRGLQLHSAGSPARLEASWSDAPGDQDSYQ
                     LLLYHLESQTLACNVSVSPDTLSYSFGDLLPGTQYVLEVITWAGSLHAKTSILQWTEP
                     VPPDHLALRALGTSSLQAFWNSSEGATSFHLMLTDLLGGTNTTAVIRQGVSTHTFLHL
                     SPGTPHELKICASAGPHQIWGPSATEWTYPSYPSDLVLTPLRNELWASWKAGLGARDG
                     YVLKLSGPMESTSTLGPEECNAVFPGPLPPGHYTLQLKVLAGPYDAWVEGSTWLAESA
                     ALPREVPGARLWLDGLEASKQPGRRALLYSDDAPGSLGNISVPSGATHVIFCGLVPGA
                     HYRVDIASSTGDISQSISGYTSPLPPQSLEVISRSSPSDLTIAWGPAPGQLEGYKVTW
                     HQDGSQRSPGDLVDLGPDTLSLTLKSLVPGSCYTVSAWAWAGNLDSDSQKIHSCTRPA
                     PPTNLSLGFAHQPAALKASWYHPPGGRDAFHLRLYRLRPLTLESEKVLPREAQNFSWA
                     QLTAGCEFQVQLSTLWGSERSSSANATGWTPPSAPTLVNVTSDAPTQLQVSWAHVPGG
                     RSRYQVTLYQESTRTATSIMGPKEDGTSFLGLTPGTKYKVEVISWAGPLYTAAANVSA
                     WTYPLIPNELLVSMQAGSAVVNLAWPSGPLGQGACHAQLSDAGHLSWEQPLKLGQELF
                     MLRDLTPGHTISMSVRCRAGPLQASTHLVVLSVEPGPVEDVLCHPEATYLALNWTMPA
                     GDVDVCLVVVERLVPGGGTHFVFQVNTSGDALLLPNLMPTTSYRLSLTVLGRNSRWSR
                     AVSLVCSTSAEAWHPPELAEPPQVELGTGMGVTVMRGMFGKDDGQIQWYGIIATINMT
                     LAQPSREAINYTWYDHYYRGCESFLALLFPNPFYPEPWAGPRSWTVPVGTEDCDNTQE
                     ICNGRLKSGFQYRFSVVAFSRLNTPETILAFSAFSEPRASISLAIIPLTVMLGAVVGS
                     IVIVCAVLCLLRWRCLKGPRSEKDGFSKELMPYNLWRTHRPIPIHSFRQSYEAKSAHA
                     HQTFFQEFEELKEVGKDQPRLEAEHPDNIIKNRYPHVLPYDHSRVRLTQLPGEPHSDY
                     INANFIPGYSHTQEIIATQGPLKKTLEDFWRLVWEQQVHVIIMLTVGMENGRVLCEHY
                     WPANSTPVTHGHITIHLLAEEPEDEWTRREFQLQHGTEQKQRRVKQLQFTTWPDHSVP
                     EAPSSLLAFVELVQEQVQATQGKGPILVHCSAGVGRTGTFVALLRLLRQLEEEKVADV
                     FNTVYILRLHRPLMIQTLSQYIFLHSCLLNKILEGPPDSSDSGPISVMDFAQACAKRA
                     ANANAGFLKEYKLLKQAIKDGTGSLLPPPDYNQNSIVSRRHSQEQFALVEECPEDSML
                     EASLFPGGPSGCDHVVLTGSAGPKELWEMVWEHDAHVLVSLGLPDTKEKPPDIWPVEM
                     QPIVTDMVTVHRVSESNTTTGWPSTLFRVIHGESGKERQVQCLQFPCSESGCELPANT
                     LLTFLDAVGQCCFRGKSKKPGTLLSHSSKNTNQLGTFLAMEQLLQQAGTERTVDVFNV
                     ALKQSQACGLMTPTLEQYIYLYNCLNSALLNGLPRAGKWPAPC"
     exon            262..310
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            311..583
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            584..853
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            854..1117
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            1118..1372
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            1373..1618
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            1619..1894
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            1895..2167
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            2168..2431
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            2432..2698
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            2699..2980
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            2981..3121
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            3122..3332
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            3333..3400
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            3401..3527
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            3528..3575
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            3576..3669
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            3670..3760
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            3761..3837
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            3838..3972
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            3973..4095
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            4096..4256
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            4257..4392
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            4393..4460
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            4461..4548
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            4549..4627
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            4628..4704
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            4705..4833
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            4834..4953
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            4954..5117
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            5118..5253
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     exon            5254..5446
                     /gene="Ptprv"
                     /gene_synonym="Esp"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      5446
                     /gene="Ptprv"
                     /gene_synonym="Esp"
ORIGIN      
        1 agaacagcct acaacagctg ccttccggga gggaccaggc tagttcacac ttggaagttg
       61 ggatgccagg agcagccttc tgtcttccga ggccttcctg ggtctcctgg tcagctcatt
      121 ccacactgag atgattctaa agaaagatcc tcacacagac tctgctggaa gaaacaaagt
      181 gaagtgtccc cagactttat caggatgagg cccctgattc tgttagctgc cctcctctgg
      241 ctccagggct ttttggccga ggacgacgca tgctcatcct tggaagggag cccagacagg
      301 cagggtggag gtccacttct gagtgtgaac gtcagtagcc atggaaagtc taccagcctg
      361 tttctgagct gggtagctgc agagctgggc ggatttgact atgccctcag cctcaggagt
      421 gtgaactcct caggttctcc agaagggcaa cagctccagg ctcacacaaa tgagtccggc
      481 tttgagttcc atggcctggt gccagggagt cgctaccagc taaaactgac tgtcctaaga
      541 ccctgttggc agaatgtcac aattaccctc actgcccgaa ctgccccgac agtggtccgt
      601 ggactgcagc tgcatagcgc tgggagccca gccaggctgg aagcctcgtg gagtgatgcc
      661 cctggagatc aagacagcta ccaacttctc ctctaccacc tggaatccca aactctggca
      721 tgcaatgtct ctgtgtcccc tgacaccctg tcttacagtt ttggcgacct tttgccaggt
      781 actcagtatg tcttggaggt tatcacctgg gctggcagtc tccatgcgaa gactagtatc
      841 ctccagtgga cagagcctgt ccctcctgat cacctagcac tacgtgcctt gggtaccagt
      901 agcctgcaag ccttctggaa cagctctgaa ggggccacct cgtttcacct gatgctcaca
      961 gacctcctcg ggggcaccaa cacgactgcg gtgatcagac aaggggtctc gacccacacc
     1021 tttcttcacc tatctccggg tacacctcat gagctgaaga tttgtgcttc tgctgggccc
     1081 caccagatct ggggacccag tgccaccgag tggacctatc cctcttaccc atctgacctg
     1141 gtgctgactc ccttacggaa tgagctctgg gccagctgga aggcagggct gggagcccgg
     1201 gacggctatg tactgaagtt aagtgggcca atggagagta cgtctaccct gggcccggaa
     1261 gagtgcaatg cagtcttccc agggcccctg cctccgggac actacacttt gcagctgaag
     1321 gttctagctg gaccttatga tgcctgggtg gagggcagta cctggctggc tgaatctgct
     1381 gcccttccca gggaggtccc tggtgccaga ctgtggctag atggactgga agcttccaag
     1441 cagcctggga gacgggcgct actctattct gacgatgccc caggctccct agggaacatc
     1501 tctgtgccct ctggtgccac tcacgtcatt ttctgtggcc tggtacctgg agcccactat
     1561 agggtggaca ttgcctcatc cacgggggac atctctcaga gcatctcagg ctatacaagt
     1621 cccctgccac cgcagtcact ggaggtcatc agcaggagca gcccatctga cctgactatt
     1681 gcttggggtc cagcaccagg gcagctggaa ggttataagg ttacctggca tcaggatggc
     1741 agccagaggt ctcctggcga ccttgttgac ttgggccctg acactttgag cctgactctg
     1801 aaatctctgg tacccggctc ctgctacacc gtgtcagcat gggcctgggc cgggaacctc
     1861 gactctgact ctcagaagat tcacagctgc acccgccccg ctcctcccac caacctgagt
     1921 ctgggctttg cccaccagcc tgcggcactg aaggcttcct ggtatcaccc accgggtggc
     1981 agggatgcct ttcacttacg gctttacagg ctgaggcctc tgacactgga aagtgagaag
     2041 gtcctacctc gggaggccca gaacttctcc tgggcccagc tgactgcagg ctgtgagttc
     2101 caggtacagc tgtctacctt gtgggggtct gagagaagca gcagtgccaa cgccacaggc
     2161 tggacacccc cttcagctcc tacactggta aacgtgacca gcgatgctcc tacccagctc
     2221 caagtatcct gggcccacgt tcctgggggc cggagccgct accaagtgac cctataccag
     2281 gagagtaccc ggacagccac cagcatcatg gggcccaagg aagatggcac gagctttttg
     2341 ggtttgactc ctggcactaa gtacaaggtg gaagtcatct cctgggctgg gcccctctac
     2401 actgcagcag ccaacgtttc tgcctggacc tacccactca tacccaatga gctgctcgtg
     2461 tcaatgcagg caggcagtgc tgtggttaac ctggcctggc ccagtggtcc cctggggcaa
     2521 ggggcatgcc acgcccaact ctcagatgct ggacacctct catgggagca acccctgaaa
     2581 ctaggccaag agctcttcat gctaagggat ctcacaccag gacataccat ctcgatgtca
     2641 gtgaggtgtc gggcagggcc gctccaggcc tctacgcacc ttgtggtgct gtctgtggag
     2701 cctggccctg tggaagatgt gctctgtcat ccagaggcca cctacctggc cctgaactgg
     2761 acgatgcctg ctggagacgt ggatgtctgt ctggtggtgg tagagcggct ggtgccggga
     2821 gggggcactc attttgtctt ccaggtcaac acctcagggg atgctcttct gttgcccaac
     2881 ttgatgccca ccacttctta ccgccttagc ctcaccgttc tgggcaggaa tagtcggtgg
     2941 agccgggcgg tttccctggt gtgcagtact tctgctgagg cttggcaccc cccagagcta
     3001 gctgagcccc cccaggtgga gctggggaca gggatgggtg tgacagtcat gcgtggcatg
     3061 tttggtaaag atgacgggca gatccagtgg tatggcataa ttgccaccat caacatgacg
     3121 ctggcccagc cttcccggga agccatcaat tacacatggt atgaccacta ctatagagga
     3181 tgtgagtcct tcctggctct cctgttccca aaccccttct acccagagcc ttgggctggg
     3241 ccaagatcct ggacagtacc tgtgggtact gaggactgtg acaacaccca agagatatgc
     3301 aatgggcgtc tcaagtcagg cttccagtat aggttcagcg ttgtggcctt tagtaggctc
     3361 aacactccag agaccatcct cgccttctcg gccttctcag agccccgggc cagcatctct
     3421 ctggcgatca ttcccctgac agttatgctg ggggctgtgg tgggcagcat tgtcattgtg
     3481 tgtgcagtgc tatgcttgct ccgctggcgg tgcctgaagg gaccaagatc agagaaggat
     3541 ggcttttcca aggagctgat gccttacaac ctgtggcgga cccatcggcc tatccccatc
     3601 catagcttcc ggcagagcta tgaggccaag agcgcacatg cacaccagac cttcttccag
     3661 gaatttgagg agttgaagga ggtaggcaag gaccagcccc gactagaggc tgagcatccg
     3721 gacaacatca tcaagaaccg gtacccacac gtgctgccct atgaccactc cagggtcagg
     3781 ctgacccagc taccaggaga gcctcattct gactacatca atgccaactt catcccaggc
     3841 tatagccaca cacaggagat cattgccacc caggggcctc tcaaaaagac gctagaggac
     3901 ttctggcggt tggtatggga gcagcaagtc cacgtgatca tcatgctgac tgtgggcatg
     3961 gagaacgggc gggtactgtg tgagcactac tggccagcca actccacgcc tgttactcac
     4021 ggtcacatca ccatccacct cctggcagag gagcctgagg atgagtggac caggagggaa
     4081 ttccagctgc agcacggtac cgagcaaaaa cagaggcgag tgaagcagct gcagttcact
     4141 acctggccag accacagtgt cccggaggct cccagctctc tgctcgcttt tgtagaactg
     4201 gtacaggagc aggtgcaggc cactcagggc aagggaccca tcctggtgca ttgcagtgct
     4261 ggcgtgggga ggacaggcac ctttgtggct ctcttgcggc tactgcgaca actagaggaa
     4321 gagaaggtgg ccgatgtgtt caacactgtg tacatactcc ggttgcaccg gcccctcatg
     4381 atccagaccc tgagtcaata catcttcctg cacagttgcc tgctgaacaa gattctggaa
     4441 gggccccctg acagctccga ctccggcccc atctctgtga tggattttgc acaggcttgt
     4501 gccaagaggg cagccaacgc caatgctggt ttcttgaagg agtacaagct cctgaagcag
     4561 gccatcaagg atgggactgg ctctctgctg ccccctcctg actacaatca gaacagcatt
     4621 gtctcccgtc gtcattctca ggagcagttc gccctggtgg aggagtgccc tgaggatagc
     4681 atgctggaag cctcactctt ccctggtggt ccgtctggtt gtgatcatgt ggtgctgact
     4741 ggctcagccg gaccaaagga actctgggaa atggtgtggg agcatgatgc ccatgtgctc
     4801 gtctccctgg gcctgcctga taccaaggag aagccaccag acatctggcc agtggagatg
     4861 cagcctattg tcacagacat ggtgacagtg cacagagtgt ctgagagcaa cacaacaact
     4921 ggctggccca gcaccctctt cagagtcata cacggggaga gtggaaagga aaggcaggtt
     4981 caatgcctgc aatttccatg ctctgagtct gggtgtgagc tcccagctaa caccctactg
     5041 accttccttg atgctgtggg ccagtgctgc ttccggggca agagcaagaa gccagggacc
     5101 ctgctcagcc actccagcaa aaacacaaac cagctgggca ccttcttggc tatggaacag
     5161 ctgttacagc aagcagggac agagcgcaca gtggacgtct tcaatgtggc cctgaagcag
     5221 tcacaggcct gcggccttat gaccccaaca ctggagcagt atatctacct ctacaactgt
     5281 ctgaacagcg cactgctgaa cgggctgccc agagctggga agtggcctgc gccctgctag
     5341 gcgtcatgtt ccagcaaatc cacccaggcc tgacttccct aggagagtgg atccaccggg
     5401 cctcacactg tccaagggca gagtccagga ataaagagac atggtc
//
