LOCUS       NM_001191575            5538 bp    mRNA    linear   ROD 06-NOV-2024
DEFINITION  Rattus norvegicus protein tyrosine phosphatase, receptor type, U
            (Ptpru), transcript variant 1, mRNA.
ACCESSION   NM_001191575 XM_002729546
VERSION     NM_001191575.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5538)
  AUTHORS   Clement,L.C., Liu,G., Perez-Torres,I., Kanwar,Y.S., Avila-Casado,C.
            and Chugh,S.S.
  TITLE     Early changes in gene expression that influence the course of
            primary glomerular disease
  JOURNAL   Kidney Int 72 (3), 337-347 (2007)
   PUBMED   17457373
REFERENCE   2  (bases 1 to 5538)
  AUTHORS   Yan,H.X., Yang,W., Zhang,R., Chen,L., Tang,L., Zhai,B., Liu,S.Q.,
            Cao,H.F., Man,X.B., Wu,H.P., Wu,M.C. and Wang,H.Y.
  TITLE     Protein-tyrosine phosphatase PCP-2 inhibits beta-catenin signaling
            and increases E-cadherin-dependent cell adhesion
  JOURNAL   J Biol Chem 281 (22), 15423-15433 (2006)
   PUBMED   16574648
REFERENCE   3  (bases 1 to 5538)
  AUTHORS   Siu,B., Saha,J., Smoyer,W.E., Sullivan,K.A. and Brosius,F.C. 3rd.
  TITLE     Reduction in podocyte density as a pathologic feature in early
            diabetic nephropathy in rodents: prevention by lipoic acid
            treatment
  JOURNAL   BMC Nephrol 7, 6 (2006)
   PUBMED   16539708
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5538)
  AUTHORS   Chin,C.N., Sachs,J.N. and Engelman,D.M.
  TITLE     Transmembrane homodimerization of receptor-like protein tyrosine
            phosphatases
  JOURNAL   FEBS Lett 579 (17), 3855-3858 (2005)
   PUBMED   15978577
REFERENCE   5  (bases 1 to 5538)
  AUTHORS   Yan,H.X., He,Y.Q., Dong,H., Zhang,P., Zeng,J.Z., Cao,H.F., Wu,M.C.
            and Wang,H.Y.
  TITLE     Physical and functional interaction between receptor-like protein
            tyrosine phosphatase PCP-2 and beta-catenin
  JOURNAL   Biochemistry 41 (52), 15854-15860 (2002)
   PUBMED   12501215
REFERENCE   6  (bases 1 to 5538)
  AUTHORS   Wharram,B.L., Goyal,M., Gillespie,P.J., Wiggins,J.E., Kershaw,D.B.,
            Holzman,L.B., Dysko,R.C., Saunders,T.L., Samuelson,L.C. and
            Wiggins,R.C.
  TITLE     Altered podocyte structure in GLEPP1 (Ptpro)-deficient mice
            associated with hypertension and low glomerular filtration rate
  JOURNAL   J Clin Invest 106 (10), 1281-1290 (2000)
   PUBMED   11086029
REFERENCE   7  (bases 1 to 5538)
  AUTHORS   Cheng,J., Wu,K., Armanini,M., O'Rourke,N., Dowbenko,D. and
            Lasky,L.A.
  TITLE     A novel protein-tyrosine phosphatase related to the homotypically
            adhering kappa and mu receptors
  JOURNAL   J Biol Chem 272 (11), 7264-7277 (1997)
   PUBMED   9054423
REFERENCE   8  (bases 1 to 5538)
  AUTHORS   Sommer,L., Rao,M. and Anderson,D.J.
  TITLE     RPTP delta and the novel protein tyrosine phosphatase RPTP psi are
            expressed in restricted regions of the developing central nervous
            system
  JOURNAL   Dev Dyn 208 (1), 48-61 (1997)
   PUBMED   8989520
REFERENCE   9  (bases 1 to 5538)
  AUTHORS   Kitamura,T., Nakamura,K., Mizuno,Y. and Kikuchi,K.
  TITLE     Gene expressions of protein tyrosine phosphatases in regenerating
            rat liver and rat ascites hepatoma cells
  JOURNAL   Jpn J Cancer Res 86 (9), 811-818 (1995)
   PUBMED   7591957
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Dec 20, 2022 this sequence version replaced NM_001191575.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386
                              [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-196               JAXUCZ010000005.1  149308638-149308833 c
            197-328             JAXUCZ010000005.1  149294461-149294592 c
            329-600             JAXUCZ010000005.1  149291272-149291543 c
            601-682             JAXUCZ010000005.1  149290753-149290834 c
            683-798             JAXUCZ010000005.1  149290532-149290647 c
            799-973             JAXUCZ010000005.1  149290092-149290266 c
            974-1267            JAXUCZ010000005.1  149289367-149289660 c
            1268-1576           JAXUCZ010000005.1  149277377-149277685 c
            1577-1686           JAXUCZ010000005.1  149272994-149273103 c
            1687-1888           JAXUCZ010000005.1  149272531-149272732 c
            1889-1991           JAXUCZ010000005.1  149272119-149272221 c
            1992-2265           JAXUCZ010000005.1  149269503-149269776 c
            2266-2302           JAXUCZ010000005.1  149268862-149268898 c
            2303-2441           JAXUCZ010000005.1  149267949-149268087 c
            2442-2471           JAXUCZ010000005.1  149265051-149265080 c
            2472-2629           JAXUCZ010000005.1  149263646-149263803 c
            2630-2820           JAXUCZ010000005.1  149253955-149254145 c
            2821-2896           JAXUCZ010000005.1  149253319-149253394 c
            2897-2973           JAXUCZ010000005.1  149252889-149252965 c
            2974-3010           JAXUCZ010000005.1  149246417-149246453 c
            3011-3108           JAXUCZ010000005.1  149245726-149245823 c
            3109-3225           JAXUCZ010000005.1  149245521-149245637 c
            3226-3380           JAXUCZ010000005.1  149244663-149244817 c
            3381-3516           JAXUCZ010000005.1  149242738-149242873 c
            3517-3666           JAXUCZ010000005.1  149242175-149242324 c
            3667-3840           JAXUCZ010000005.1  149240075-149240248 c
            3841-3981           JAXUCZ010000005.1  149238383-149238523 c
            3982-4107           JAXUCZ010000005.1  149237325-149237450 c
            4108-4265           JAXUCZ010000005.1  149237068-149237225 c
            4266-4401           JAXUCZ010000005.1  149235951-149236086 c
            4402-5538           JAXUCZ010000005.1  149234624-149235760 c
FEATURES             Location/Qualifiers
     source          1..5538
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..5538
                     /gene="Ptpru"
                     /note="protein tyrosine phosphatase, receptor type, U"
                     /db_xref="GeneID:116680"
                     /db_xref="RGD:620782"
     exon            1..196
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     CDS             124..4464
                     /gene="Ptpru"
                     /EC_number="3.1.3.48"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; R-ptp-psi; receptor-type tyrosine-protein
                     phosphatase U"
                     /codon_start=1
                     /product="receptor-type tyrosine-protein phosphatase U
                     isoform 1 precursor"
                     /protein_id="NP_001178504.1"
                     /db_xref="GeneID:116680"
                     /db_xref="RGD:620782"
                     /translation="MARAQALVLALTFQFCAPETETPAAGCTFEEASDPVVPCEFSQA
                     QYDDFQWEQVRIHPGTRTPADLPHGAYLMVNASQHAPGQRAHIIFQTLSENDTHCVQF
                     SYFLFSRDGHSPGTLGVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQV
                     LFEALISPDHKGYIGLDDILLFSHPCAKAPHFSRLGDVEVNAGQNASFQCMAAGRAAE
                     AERFFLQRQSGVLVPAAGVRHISHRRFLATFPLASVGRSEQDLYRCVSQAPRGAGVSN
                     FAELIVKEPPTPIAPPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEIEYRMARGPWAEV
                     HAVNLQTYKLWHLDPDTEYEISVLLTRPGDGGTGRPGPPLLSRTKCAEPTRAPKGLAF
                     AEIQARQLTLQWEPLGYNVTRCHTYAVSLCYHYTLGGSHNQTIRECVKMERGASRYTI
                     KNLLPFRNVHVRLILTNPEGRKEGKEVTFQTDEDVPGGIAAESLTFTPLEDMIFLKWE
                     EPQEPNGLITQYEISYQSIESSDPAVNVPGPRRTISKLRNETYHVFSNLQPGTTYLFS
                     VRARTSKGFGQAALTEITTNISAPSFDYADMPSPLGESENTITVLLRPAQGRGAPISV
                     YQVVVEEERPRRLRREPGGQDCFSVPLTFETALARGLVHYFGAELAASSLLEAMPFTV
                     GDNQTYRGFWNPPLEPRKAYLIYFQAASHLKGETRLNCIRIARKAACKESKRPLEVSQ
                     RSEEMGLILGICAGGLAVLILLLGAIIIIIRKGRDRYAYSYYPKPVNMAKATVNYRQE
                     KTHMMTAVDRSFTDQSTLQEDERLGLSFMDAPGYSPRGDQRSSGVTEASSLLGGSPRR
                     PCGRKGSPYHTGQLHPAVRVADLLQHINQMKTAEGYGFKQEYESFFEGWDATKKKDKL
                     KSGRQEPVSAYDRHRVKLHPMLGDPDADYISANYIDGYHRSNHFIATQGPKPEMIYDF
                     WRMVWQEQCVSVVMISKLVEVGRVKCSRYWPEDSDMYGDIKITLVKTETLAEYVVRTF
                     ALERRGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPDAGPVVIHCSAG
                     TGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACL
                     CGETTIPVNEFKATYREMIRIDPQSNSSQLREEFQTLNSVTPPLDVEECSIALLPRNR
                     DKNRSMDVLPPDRCLPFLISSDGDPNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFW
                     RLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQYGLMEVEFVSGTANEDLVSRV
                     FRVQNSSRLQEGHLLVRHFQFLRWSAYRDTPDSRKAFLHLLAEVDKWQAESGDGRTVV
                     HCLNGGGRSGTFCACATVLEMIRCHSLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVA
                     LEYLEALELR"
     exon            197..328
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            329..600
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            601..682
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            683..798
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            799..973
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            974..1267
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            1268..1576
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            1577..1686
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            1687..1888
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            1889..1991
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            1992..2265
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            2266..2302
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            2303..2441
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            2442..2471
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            2472..2629
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            2630..2820
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            2821..2896
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            2897..2973
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            2974..3010
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            3011..3108
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            3109..3225
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            3226..3380
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            3381..3516
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            3517..3666
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            3667..3840
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            3841..3981
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            3982..4107
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            4108..4265
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            4266..4401
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
     exon            4402..5538
                     /gene="Ptpru"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtcccgctc cgcgcggcgc tgctccgcta ccgctcccgc tcgccttggg ctccggcttc
       61 ggctccggag gcgtcgcctc cccagctacc ggtctccagg acccaggcgg cggcgcccca
      121 gccatggccc gagctcaggc tctggtcctg gcgctcacct tccagttctg cgcgcccgag
      181 accgagactc ccgcagctgg ctgcaccttc gaggaggcga gtgacccggt tgtgccctgc
      241 gagttcagcc aggctcagta tgatgacttc cagtgggagc aagtacggat ccaccctggc
      301 acccggaccc ctgcagacct gccccatggt gcctacttga tggttaatgc ttcccagcat
      361 gctccaggcc agagggccca tatcatcttc cagaccctga gcgagaacga cacccactgt
      421 gtgcagttca gctacttcct gtttagccgg gatgggcaca gcccaggcac cctgggcgtc
      481 tatgtgcgtg tgaacggggg ccctctgggc agtgccgtgt ggaatatgac tggatcccac
      541 ggccgtcagt ggcatcaggc tgaactggct gtcagcacct tctggcccaa tgagtatcag
      601 gtgctgtttg aggctctcat ctccccagac cataagggct acataggctt agatgacatc
      661 ttgctattca gccatccctg cgcgaaggcc cctcacttct cccgccttgg agacgtggag
      721 gtcaatgcgg gccagaatgc atccttccaa tgcatggcag caggcagagc tgcagaggca
      781 gagcgtttct tcctgcagcg gcagagtggg gtgctagtgc ctgcggctgg ggtgcggcac
      841 atcagtcacc gtcgcttcct ggccactttt ccactggcct ctgtaggccg ctcggagcag
      901 gatctgtacc gttgcgtgtc ccaggccccg cgcggtgctg gagtctccaa cttcgcagag
      961 ctcatcgtca aagagcctcc cacccccatc gcgcccccac agctgctgcg tgcaggcccc
     1021 acctacctca tcatccagct caacaccaac tccatcattg gcgacgggcc gatcgtgcgc
     1081 aaggagatcg agtaccgaat ggcacggggc ccgtgggccg aggttcacgc tgtcaacctg
     1141 cagacctaca agctgtggca tctagacccg gacactgagt atgagatcag cgtgctgctt
     1201 acccgcccgg gagatggagg cacaggccgc ccagggccac cactgctcag ccggaccaag
     1261 tgcgcagagc ccacgagggc ccccaagggc ctggcttttg ctgagatcca ggctcgtcag
     1321 ctgaccctgc agtgggagcc cctgggctac aatgtcacgc gttgtcatac ctatgctgtg
     1381 tccctttgtt atcactacac cctgggcggc agccacaacc agaccatccg ggagtgtgtg
     1441 aagatggagc ggggcgccag ccgctacacc atcaagaatc tgctgccgtt caggaacgtc
     1501 cacgtgcgtc tgattctcac aaaccctgag gggcgcaagg agggcaagga ggtcaccttc
     1561 cagacagatg aagatgtgcc tggtgggatc gccgctgagt ctctcacctt caccccacta
     1621 gaggacatga tctttctcaa gtgggaggag ccccaggaac ccaatggcct catcactcag
     1681 tatgagatca gctaccaaag cattgagtcc tcagacccag cggtgaacgt gcccggcccg
     1741 agacgcacca tctccaaact ccgaaatgag acttaccatg tcttctccaa cctgcaaccc
     1801 ggcaccacat acctgttctc tgtgcgtgct cgtacaagca agggctttgg ccaggcggct
     1861 ctcaccgaga taaccaccaa catctcagca cccagctttg attatgccga catgccgtca
     1921 cccctgggcg agtctgagaa caccatcact gtgctgttga ggccggccca gggccgagga
     1981 gcacccatca gcgtctacca ggtggttgtg gaggaagagc ggccacggcg cttgcggcgc
     2041 gagcctggag gtcaggactg cttctcggta cctctgacct ttgagacggc cctggctcgc
     2101 ggcctggtgc actactttgg ggctgaactg gctgccagca gcctgcttga ggccatgccc
     2161 ttcactgtgg gtgacaacca gacctatcgt ggcttctgga acccaccgct tgagcccagg
     2221 aaggcctacc tcatctattt ccaggcagcg agccacctga aaggggaaac ccgactgaac
     2281 tgcatccgaa ttgccaggaa agctgcgtgc aaggagagca agcgacccct cgaagtgtcc
     2341 cagaggtcgg aggagatggg gctcatcctg ggtatctgtg caggtggcct tgccgtcctc
     2401 attctcctcc tgggcgccat cattatcatc atccgtaaag ggagggaccg ctatgcctac
     2461 tcttactacc cgaagccagt gaacatggca aaagccacgg tcaactatcg ccaggagaag
     2521 acccacatga tgactgctgt ggaccgtagc ttcacagatc agagcactct gcaggaggat
     2581 gagcggctgg gcctgtcctt catggatgct cctggctaca gccctcgggg agaccagaga
     2641 agcagtgggg tcactgaggc cagtagcctc ctggggggct ctcctcggcg cccctgtggc
     2701 cggaagggct ccccgtatca cacagggcag cttcaccctg cagtacgagt ggctgacctg
     2761 ctgcagcaca tcaaccagat gaagacagcc gagggctacg gcttcaagca agagtacgag
     2821 agtttctttg aaggctggga tgccaccaag aagaaagaca agctgaagag cggccggcag
     2881 gagccagtgt ctgcctatga ccgacaccga gtgaagctgc acccgatgct gggagaccct
     2941 gatgccgact acatctctgc caactacata gacggctacc acaggtcaaa ccacttcata
     3001 gccactcaag ggccaaagcc tgagatgatc tacgacttct ggcgcatggt gtggcaggag
     3061 cagtgtgtga gcgtcgtcat gatcagcaag ctggtagagg tgggcagggt aaagtgctct
     3121 cgatactggc ccgaggactc agacatgtat ggggacatca agatcacgct ggtaaagaca
     3181 gagacactgg ctgagtacgt ggtgcgcacc tttgccctgg agcggagagg ttactcagcc
     3241 cggcatgagg tccgccagtt ccacttcaca gcgtggccag agcatggtgt tccctaccat
     3301 gccacggggc tgctggcctt catccggcgc gtgaaggctt ccactccacc tgatgctggg
     3361 cctgttgtca ttcactgcag tgcaggcact ggccgcacag gctgctacat cgtcttggat
     3421 gtgatgctgg acatggctga gtgtgagggg gtcgtggaca tttacaactg cgtgaagacc
     3481 ctctgttccc ggcgggtcaa catgatccag accgaggaac aatacatctt catccacgat
     3541 gcgattctgg aggcctgcct gtgtggggag accaccatcc ctgtcaatga gttcaaggcc
     3601 acctataggg agatgatccg cattgaccct cagagtaact cctcccagct tcgggaagag
     3661 ttccagacac tgaactcggt cacaccgccg ctggacgtgg aggagtgtag cattgccctg
     3721 ctgccccgga atcgagacaa gaaccgtagc atggacgtgc tgccgccaga ccgctgcctg
     3781 cccttcctca tctccagtga tggggacccc aacaactaca tcaatgcagc cctaactgat
     3841 agctacacac ggagcgccgc cttcatcgtg accctgcacc cactgcagag taccacaccc
     3901 gacttctggc ggctggtcta cgactatggg tgcacctcca ttgtgatgct caaccagctt
     3961 aaccagtcca actccgcctg gccctgcctg cagtactggc cagaaccagg cagacagcag
     4021 tatggcctca tggaggtgga gtttgtgtct ggcacagcaa acgaggatct ggtgtcccga
     4081 gtgttccggg tgcagaactc ttcaaggctg caggagggcc acctgctggt tcgtcacttt
     4141 cagttcctgc gttggtctgc ttatcgggac acgcctgact ccaggaaggc cttcctgcac
     4201 ctgttggctg aggtggacaa gtggcaggcg gagagtggag atgggcgcac cgtggtgcat
     4261 tgtctcaatg gcggtggccg cagtggcacc ttctgcgcct gtgcaacggt cttggaaatg
     4321 atccgctgtc acagcctggt ggatgttttc tttgctgcca aaacgcttcg gaactacaag
     4381 cccaatatgg tggagaccat ggatcaatac catttctgct acgatgtggc cctggagtac
     4441 ctggaggctc tggagttgag atagcaggcg cctggactgg ggcacccagt gaacacccag
     4501 ggcatggccc atcattccag actggtgagg agggcctgtg gccccaactt tgctcagcca
     4561 taatcctaca gggagaacac aggagcggat gctgcaccgt ctcggtgacc cccacgggaa
     4621 ggctgcagac caaggaggag ctttgcaaga ctgtttcagc cccacctcca gagggccctg
     4681 tagaactgtg ccgagaagct ggcctgggac agtggcactg gccaaaatag ctagtgctgg
     4741 ggaccccagg ctagaccttc cactccatta cagtccttgg caagaaacga atgaggatct
     4801 gcagagagtg tccaaggttt gcacccagtg tggtcccttt ggcacgtggc ggaagctcac
     4861 tggggcttgg ctggggctga gtcccagctg gctgagcccc cgagagtcct gaagccggga
     4921 ctcctccttg tcttggcagt gggacacact gagcatcctg cagctccttt ctccatccca
     4981 ctgcccttgc agacccaggg gtgctttgct tgacaatgct ttcctcctgc ttctgagctt
     5041 ttcctgcaac aggagcctcc ctcctgggct ccatccctgc ctggcccagt atatgcagaa
     5101 tgatacactt cagctccttc ttccctagcc ttcaggtcgc catggctcgg tcctgctcag
     5161 cttgggcctg tgacaatcca caaggctgac tcacagcccc ctggggtgga ggtccctgtg
     5221 gctcttggtg aggtggtcac tggatcaggg tggagtagag caaggctggg gccagctccc
     5281 agagttcaga gaaagaaggg gtgctttggg atggggacca gtgctttctt tctttgttgt
     5341 tgttattttg ttttttgatg ggagggtagg aagttctctt tataatgggg taggccacac
     5401 ccccatttcg tgcctcaatt tccccatctg taaactgtag atatgactac tgacctacct
     5461 cacagggggc tgtggggagg tgtaaggtaa tgtttgtaaa gcgctttgta aataaatgtg
     5521 ctctctgaat gccaccca
//
