LOCUS       NM_001100479           10584 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus protein tyrosine phosphatase, non-receptor type 4
            (Ptpn4), mRNA.
ACCESSION   NM_001100479 XM_001053943 XM_039090323 XM_341109
VERSION     NM_001100479.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 10584)
  AUTHORS   Ge,L., Cai,Y., Ying,F., Liu,H., Zhang,D., He,Y., Pang,L., Yan,D.,
            Xu,A., Ma,H. and Xia,Z.
  TITLE     miR-181c-5p Exacerbates Hypoxia/Reoxygenation-Induced Cardiomyocyte
            Apoptosis via Targeting PTPN4
  JOURNAL   Oxid Med Cell Longev 2019, 1957920 (2019)
   PUBMED   31178952
  REMARK    GeneRIF: The overexpression of miR-181c-5p significantly attenuated
            the mRNA and protein expression of PTPN4 in H9C2 cardiomyocytes.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10584)
  AUTHORS   Heneberg,P. and Draber,P.
  TITLE     Nonreceptor protein tyrosine and lipid phosphatases in type I
            fc(epsilon) receptor-mediated activation of mast cells and
            basophils
  JOURNAL   Int Arch Allergy Immunol 128 (4), 253-263 (2002)
   PUBMED   12218363
  REMARK    Review article
REFERENCE   3  (bases 1 to 10584)
  AUTHORS   Park,K.W., Lee,E.J., Lee,S., Lee,J.E., Choi,E., Kim,B.J., Hwang,R.,
            Park,K.A. and Baik,J.
  TITLE     Molecular cloning and characterization of a protein tyrosine
            phosphatase enriched in testis, a putative murine homologue of
            human PTPMEG
  JOURNAL   Gene 257 (1), 45-55 (2000)
   PUBMED   11054567
REFERENCE   4  (bases 1 to 10584)
  AUTHORS   Gjorloff-Wingren,A., Saxena,M., Han,S., Wang,X., Alonso,A.,
            Renedo,M., Oh,P., Williams,S., Schnitzer,J. and Mustelin,T.
  TITLE     Subcellular localization of intracellular protein tyrosine
            phosphatases in T cells
  JOURNAL   Eur J Immunol 30 (8), 2412-2421 (2000)
   PUBMED   10940933
REFERENCE   5  (bases 1 to 10584)
  AUTHORS   Gu,M. and Majerus,P.W.
  TITLE     The properties of the protein tyrosine phosphatase PTPMEG
  JOURNAL   J Biol Chem 271 (44), 27751-27759 (1996)
   PUBMED   8910369
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            On or before Jun 3, 2021 this sequence version replaced
            XM_039090323.1, NM_001100479.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360190.3342369.1,
                                           SRR26643293.52954.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-450               JAXUCZ010000013.1  33504508-33504957   c
            451-605             JAXUCZ010000013.1  33469447-33469601   c
            606-713             JAXUCZ010000013.1  33453270-33453377   c
            714-756             JAXUCZ010000013.1  33435755-33435797   c
            757-835             JAXUCZ010000013.1  33435579-33435657   c
            836-880             JAXUCZ010000013.1  33430393-33430437   c
            881-933             JAXUCZ010000013.1  33429856-33429908   c
            934-1054            JAXUCZ010000013.1  33429461-33429581   c
            1055-1142           JAXUCZ010000013.1  33419937-33420024   c
            1143-1231           JAXUCZ010000013.1  33415858-33415946   c
            1232-1295           JAXUCZ010000013.1  33398604-33398667   c
            1296-1468           JAXUCZ010000013.1  33394947-33395119   c
            1469-1537           JAXUCZ010000013.1  33382895-33382963   c
            1538-1663           JAXUCZ010000013.1  33376825-33376950   c
            1664-1822           JAXUCZ010000013.1  33375011-33375169   c
            1823-1982           JAXUCZ010000013.1  33366291-33366450   c
            1983-2066           JAXUCZ010000013.1  33364799-33364882   c
            2067-2123           JAXUCZ010000013.1  33364654-33364710   c
            2124-2280           JAXUCZ010000013.1  33360136-33360292   c
            2281-2447           JAXUCZ010000013.1  33357416-33357582   c
            2448-2538           JAXUCZ010000013.1  33355407-33355497   c
            2539-2600           JAXUCZ010000013.1  33355181-33355242   c
            2601-2747           JAXUCZ010000013.1  33352741-33352887   c
            2748-2876           JAXUCZ010000013.1  33351250-33351378   c
            2877-3025           JAXUCZ010000013.1  33345781-33345929   c
            3026-3161           JAXUCZ010000013.1  33341807-33341942   c
            3162-10584          JAXUCZ010000013.1  33324808-33332230   c
FEATURES             Location/Qualifiers
     source          1..10584
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q11"
     gene            1..10584
                     /gene="Ptpn4"
                     /note="protein tyrosine phosphatase, non-receptor type 4"
                     /db_xref="GeneID:246116"
                     /db_xref="RGD:620712"
     exon            1..450
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            451..605
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     CDS             468..3248
                     /gene="Ptpn4"
                     /EC_number="3.1.3.48"
                     /codon_start=1
                     /product="tyrosine-protein phosphatase non-receptor type
                     4"
                     /protein_id="NP_001093949.1"
                     /db_xref="GeneID:246116"
                     /db_xref="RGD:620712"
                     /translation="MTARFRLPAGRTYNVRASELARDRQHTEVVCNILLLDNTVQAFR
                     VNKHDQGQVLLDIVFKHLDLTERDYFGLQLADDSTDNPRWLDPNKPIRKQLKRGSPYN
                     LNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILTGRLSCPCNTAALLASFAVQSELGD
                     YNQSENLAGYLSDYSFIPNQPQDFEKEIAKLHQQHIGLSPAEAEFNYLNTARTLELYG
                     VEFHYARDQSNNEILIGVMSGGILIYKNRVRMNTFLWLKIVKISFKCKQFFIQLRKEL
                     HESRETLLGFNMVNYRACKTLWKACVEHHTFFRLDRPLPPQKNFFAHYFTLGSKFRYC
                     GRTEVQSVQYGKEKANKDRVFARSPSKPLARKLMDWEVVSRNSLSDDRLETQSLPSRS
                     PPGTPNHRNSSFTQEGTRVRPSSVGHLVDHVVHTSPSEDFVSQRSPSSTQANSIVLES
                     SPSQETPEDGQPPALPPKQSKKNSWNQIHFSHSQQDLVNHTNESFDVPSSPEKSTPNG
                     GIPHDNLVLIKMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNEGDQV
                     VLINGRDIAEHTHDQVVLFIKASCERHSGELVLLVRPNAVYDVVEEKLESEPDFQYIP
                     EKAPLDSVHQDDHSLRESMIQLAEGLITGTVLAQFDQLYRKKPGMTMSCAKLPQNISK
                     NRYRDISPYDATRVLLKGNEDYINANYINMEISSSSIINQYIACQGPLPHTCKDFWQM
                     TWEQGSSMVVMLTTQVERGRVKCHQYWPEPSGSSSYGCYQVTCHSEEGNPAYIFRKMT
                     LFNQEKNESRQLTQIQYTAWPDHGVPDDSSDFLDFVCHVRNKRAGKEEPIIVHCSAGI
                     GRTGVLITMETAMCLIECNQPVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKVYEE
                     GFVKPLTTSSNK"
     exon            606..713
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            714..756
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            757..835
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            836..880
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            881..933
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            934..1054
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            1055..1142
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            1143..1231
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            1232..1295
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            1296..1468
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            1469..1537
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            1538..1663
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            1664..1822
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            1823..1982
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            1983..2066
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            2067..2123
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            2124..2280
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            2281..2447
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            2448..2538
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            2539..2600
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            2601..2747
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            2748..2876
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            2877..3025
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            3026..3161
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
     exon            3162..10584
                     /gene="Ptpn4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agccgcctcc ctggagtcac ccgccgcctc tcgccgcgcg cgcttccctg ctccgcggac
       61 gcgacattgt tcttgaagac tcccgggacc tgtcagaaat cggggctccg ggacttgaaa
      121 gagacttgac ttcggctcgc gggttgcggg gaccgcggta ctttcggggc gcgtgtgagg
      181 ggattagctc atctcgccgc gaggtgcgag cgcgtgcctc cccgcgcacg ctggccccgc
      241 cgcagccccg caggatgacg gggtgcaggc ggcccgcggc cgtggcgcgg ccgctgtggc
      301 ggcggctgtt cgcggggcgc tgagggcgag cacccggacg cggaccacgc gcccctttcc
      361 cccggccacg agcccggggc ctcctggctt tttgtatttg gattttgttt ttctttcccc
      421 agccgagagg acgcggctgt gacaacgaag gttttgtgcg gacagtaatg accgcacgtt
      481 tccgattgcc tgctggcaga acctacaatg tccgagcatc agagttggcc cgagacagac
      541 agcatacaga ggtggtttgc aacattcttc ttctggataa cactgtacag gcattcagag
      601 ttaataaaca tgatcagggg caagttctgt tggatatagt cttcaagcat cttgatctga
      661 ctgagcgaga ctattttggt ttacagttgg ctgatgattc cacagataac ccaaggtggc
      721 tggatccaaa caaaccaata aggaagcagc taaagagagg atcaccttac aatttgaact
      781 ttagagtcaa attctttgta agtgacccca acaagttaca agaagaatat acaaggtatc
      841 agtatttttt gcaaattaag caagacattc ttactggaag attatcctgt ccttgtaaca
      901 ctgctgctct tttagcttca ttcgctgttc agtctgaact tggagactac aatcagtcag
      961 aaaacttggc aggctacctc tcagattatt ctttcattcc taatcaacct caagatttcg
     1021 agaaagaaat tgcaaagtta catcagcagc atattggctt atctcctgca gaagcagaat
     1081 ttaattacct aaacacagca cgtaccctgg aactctatgg agttgaattt cactatgcaa
     1141 gggatcaaag taacaatgaa atcctgattg gagtgatgtc aggaggaatt ctgatttaca
     1201 agaacagggt acggatgaat acttttctgt ggttgaagat tgtaaaaatt tcttttaaat
     1261 gcaaacaatt ttttattcaa cttcgaaaag aattgcatga atctagagaa acattacttg
     1321 gatttaatat ggtgaattat agagcgtgta aaactttgtg gaaagcgtgt gtagaacatc
     1381 acacattctt ccgcctggat agaccacttc cacctcaaaa gaactttttt gcacattatt
     1441 ttacattggg ttccaaattc cggtactgtg ggagaactga agtccagtca gttcagtatg
     1501 gcaaagaaaa ggcaaataaa gacagggtat ttgcaagatc tccaagtaag cctttggccc
     1561 ggaaattaat ggattgggaa gtagtcagca gaaattcgtt atctgatgac aggttagaaa
     1621 cacaaagtct cccatcccgg tctccacctg gaactcccaa ccatcgaaat tcttcattca
     1681 cacaagaggg gacccgggtt cggccgtctt cagttggtca tttggtagac catgtggttc
     1741 atacatcccc cagtgaggat tttgtaagtc agagatctcc atcatcaacg caagctaata
     1801 gcatagttct ggaatcatca ccatcacaag agacccctga agatgggcag cctccagctt
     1861 taccacccaa acaatctaag aaaaacagtt ggaaccaaat tcatttttca cattctcagc
     1921 aagatctagt caaccatact aatgaatcct ttgatgtgcc ctcttcccct gaaaagtcca
     1981 ctcctaatgg tggcattcca catgataacc ttgttctaat caaaatgaaa cctgatgaga
     2041 atggaaggtt tggattcaat gtaaagggag ggtatgatca gaagatgcct gtaattgtgt
     2101 cccgggtagc accaggaaca cctgctgacc tctgtgtccc tcggttgaat gaaggggacc
     2161 aagtggtact cataaatggc cgggatattg cagaacacac ccatgatcaa gtagtcttat
     2221 ttattaaagc tagctgtgag agacattctg gggaacttgt gctcctagtt cgacctaatg
     2281 ctgtatatga cgtagtggaa gaaaaactag aaagtgagcc agacttccag tatattcctg
     2341 aaaaagcccc tctagatagt gtccatcaag atgaccattc cctgcgggag tcgatgatcc
     2401 agctagctga ggggcttatc actggaacag tactggcaca gtttgatcaa ctgtatcgga
     2461 aaaaacctgg aatgacaatg tcttgtgcca aattacctca gaacatttcc aaaaacagat
     2521 acagagatat ttcaccttat gacgctacac gggtcctttt aaaaggtaat gaagactaca
     2581 tcaatgcaaa ctatataaat atggaaattt cttcttcgag tattataaat caatacattg
     2641 cttgtcaagg gccattacca catacttgta aagatttttg gcaaatgact tgggaacaag
     2701 gctcctccat ggttgtgatg ttgaccacac aagttgaacg tggcagagtt aaatgtcacc
     2761 agtattggcc agaaccctca ggaagctcat cctatggatg ctatcaagtc acctgccact
     2821 ctgaagaagg aaatcctgcg tatatcttca ggaaaatgac actgtttaac caagagaaaa
     2881 atgagagtcg ccaactcact cagattcagt acacagcctg gcctgaccat ggggtacctg
     2941 acgactcaag tgactttctg gatttcgttt gtcatgtccg aaacaagagg gctggaaaag
     3001 aagagccgat tattgttcat tgcagtgctg gaataggaag gactggggtt ctcatcacta
     3061 tggaaactgc tatgtgtctc attgaatgca atcagccagt gtatccacta gacattgtaa
     3121 gaacaatgag agatcaaaga gccatgatga tccaaacccc tagtcaatac agatttgtat
     3181 gtgaagctat tttgaaagtt tatgaagaag gctttgttaa accattaaca acatcatcaa
     3241 ataaataaga aagcaaaaag gttggaataa gtactgggaa cctgagtttg ttacattcac
     3301 tgtgccataa tactgcttgc aggaaatggc ctctcacaca aaaagtgaag aactcaaaga
     3361 gacctcgaga acttcagcac tactgcactt tatgtttcaa aaagtcactc agaacttacc
     3421 acatgtttga atactttgtg ctttgctctg aacaaatagt ggaaactggg tatgttcaga
     3481 gtaatttatg gaattgtgag gcattgccat gcagtccctt ctggtagaat tgccgccgac
     3541 aaggctcaga ttctcatctc tgtcacacac ctgtaccttg aaagcagaag gagttatcat
     3601 caggagtctg ctctggattt tcccaggggt catgccctca ctctactgat taccagattt
     3661 tatttttcaa acgttagcaa taccattctc aacattagcc agtacactgc ctgtgggtgc
     3721 agcacatctt cctaacgtcc ccgtggggac ctgctgttga gaagaaaatt ggaacttgct
     3781 gttcccagga aatgctgcac agtgtccatt taccagcatc ttatagaaat aactatgaat
     3841 tttcttggat ttaataatgt aacttatatt tatcataagg ttggcttatt ccaaatcatg
     3901 tgatttcaca gtcttgatgt aaaggaatgc atgcatcgtg tcttaacccc ttaagtgcct
     3961 tgagatatct ttgtctaatg aaaaggcact catttgaccc cataggaggt atgtatgtat
     4021 actgtacatt cttatagttt tacgaatttt taatgagatc acagtgtttt aaaaagctgt
     4081 tttaaaaacc agcttcttat gttgagagtt atacaaacag caaagggtaa ggccattctg
     4141 tcttttactc agtgcttgta ctttgccgta aaagccagga tatctgtatt ctgcccagag
     4201 tgcatctgct gctatggaat tgttcacaat ctgcacattc ctttaccgaa gggaaggata
     4261 ggggttaaag tttagcagct taacttaaaa agagggttta ttcttcagat ttcacattta
     4321 ctttatccta aggtaagaat tgatgtttaa tatgtgcatc aaagataaat atattggtat
     4381 tctaggttac agtgagaaag tcgatcagct gggttatgca cccgtaactg acgagctgcc
     4441 ctggagcatc atcactccaa ggcctgtcag gctggctcac actgctcctt ccttccactg
     4501 gggttcttca cacaaggagt taaacacttt agcattctct aaagtgaccc ttccttgtca
     4561 tccagtttat atatgcctgt taaattataa gcatgtcagt aagtaggcca tcttaacgga
     4621 agatccaact cccattacag atatgtctgt tttccttgtt ttaagtctgt ggagacagat
     4681 ttttaaaatt gcacaattta atgtgagaac ttgctcacct attcacatgt tattttataa
     4741 ggatatggtt aaaatagaca catttactag tggttttcag attacttctg tagtctcgat
     4801 aaaacatagg tcccaatggt agatattttg gaatgctatt tagttgaggg aatgatacac
     4861 atttaaaaaa tctttagtaa catataaatt attgcttcag gtattcagaa cccataatag
     4921 taaaattcaa aagttaagct tctaaatatt aattgccagg gtaccaaata aattggcact
     4981 tataaatact tcttgtcttt tttttaaaga aagaaataaa catctttaca tcaaacagaa
     5041 gtccccttat tatgatttca caagcaagac aataatataa gttcgtaagt gaactataat
     5101 tatactcaga cattccattc tgtaaccaga ggcaaatgta atttaggctg gtaagctatc
     5161 attacaactt aaaaagggga aacaagctag agatctatgt tataaagcta ttttatttca
     5221 ttggtggatt ttagcctaaa ttttatatct tgccatgtgg gtagaaggtg ataagtgtag
     5281 acaggaagag aaaagctgtg tagaaaggca gtgtcatggt tcgtttgctc ttcaatgtaa
     5341 agctttgggt acatctctgg ttagcactga tgttggcagc aggcattgct gccttttaaa
     5401 tcagcagtgc ttaatctgaa atgacaagtg tagaattaaa ttcaaattta tcatagcagt
     5461 ttcttatctg agaactatgc tccattcgtg ttttacatct gaagacagcc cttttagaac
     5521 atttattagg atcttaagct aaacttagcc ttcacaaatt gttaatatag atatgctaac
     5581 taaactttcc tagttaccta acagaacact tgtcttttcc acctaagcat ctaaccagtt
     5641 tatgaatcta aataggttac tagaaataat gctagttttc atatgccaag tactgctcca
     5701 ctccatagat attgatataa tattgtgtga caaaaaccaa atttcttgaa ccaaactact
     5761 tttccattac tacttagcca cccttaagct cacaccccaa caaactcaag aacaaatcaa
     5821 tgcatttctt cggacaagga gaagttagta ttggtgagtt agggcttctg tacatgctaa
     5881 gagtaaatat gaaaattttc cctctcaaag ttcacatgac ttttctgctt ctttcatagg
     5941 gcatttagtt ttgtcagcac tagatgctct gtagtaatct tttggagtag actttgcatt
     6001 cacaaaaaga ataggttgta tttgttaaac taatccattc attcaaaagt gagacagaat
     6061 aaacagccca agaacagttt ttgtatagct tgctgggaca agtaattggg aaagggcaat
     6121 gattgatcat tttgacttca gaataaaggt aacattgtat aaaaaatgac ttcacaagca
     6181 gttatgctga gccattagga cagatgcttg aaaatttggg gtactactgt agctgccttc
     6241 aaagagaaac atcagtgtgt tggtttgcat gtgtacttac ttcataaaga catgttcaca
     6301 gattgaaagg acttttaacc atggggttgt ttatatctct tggcagacca agtctaatga
     6361 gttatttgaa aaaaaaaaaa tctccatgtc actagaagta gtactacacc ttgagagcta
     6421 aaaatttgaa agattttatc cactctctgt gtccttgtta ttatagaaag gactacaggc
     6481 ccaacaatta atttagcaga atctgctcat cttcaggttt tctaattctc aatttagtgt
     6541 ctctgtatta gactgtagct tcagtaaatt gtgacaaatg cttgtaagtt tttctacttg
     6601 ggaagtatgc tcagtgttgt cacttaaacc tgtaacacct tagaagttgg aaaggagact
     6661 tcaaaagtga tgccaatgag gacttggact cagttttctg gtgcttccca gacagattag
     6721 cataaactat tgtgaagtat ttaggctgat acacatgcag tataaaactg aaatgcaagt
     6781 aggaaagcat ttttaaagca cttaaaacgt ggacctgaga tttagatctt atacctactt
     6841 acaaaataat atgttcatgt gaacatgtga taaaaaggaa atatagcttg tttagcagga
     6901 agagagaagg aaacatgaac ttatagcaat atgctattta atgtctgtgt tttgaatatt
     6961 taaaatatct gatggtaaaa ttgccaaagt agtttgaatt catgtaagtt gtttatacta
     7021 caacaatgtg ggatatgttt acaggctctt tatagtgctt actttgtagt tctgatgaag
     7081 tttgtagttt gtatttaagt catttatagt aaatgtatga taaatatttg ctggaataaa
     7141 tatctcagta atatagcaaa acgtatctaa gtaatcccac agtctgcttt catacaaggt
     7201 gctttgtcca gaaaagcaag tactttgtga caccattgct tacaccccac atttgcacca
     7261 actgtccaac tacattcctg gaaccctgtg tggtgggtgc tgcctccaag taaaacagct
     7321 gtgttactat aattatatca gagttactaa tctattaaca gatatttgtg tctcagtgtg
     7381 atcacaaatt gagtgacttt tatgaaattc ttagaaaatt atatacatgc aaagaaattt
     7441 atttaatctt aaaacttttt gagggctaat tgctaataga taatgttatc aattttaaga
     7501 gtaaaagaaa tcaatcccag aattatatgt tttgagttct gctttttacc acaattctta
     7561 ttttgcatag atttcattta ctcttagtag tacttattat aatatatttc tctatgttat
     7621 cagaaacaac aacccatgta ttccggccca caattacttg attttcatgc cttattgaat
     7681 tcttttgagt aggtaccata atgttatttt ctgtttccat ctatcagtgt gacgctgctt
     7741 attttacagt tttctactgt ggaacactgt tgatttctaa agtcattatt tatttttttt
     7801 ttaagtcctc cgaaggtaaa tgagcagcca ttagttctag ctttttggtg gcagtccatc
     7861 tgtattggct aggtatggtt cagtgcataa acaagtacac cattttgcag aaagttatta
     7921 gcaatatttc aagttaaaaa ctacactgtt caggaagagt tcaaacgttt aacttcctgg
     7981 agccttgtaa attttccagt ataagaatga aaaagaaagc cttggtaagt tcataaaagt
     8041 ttcaaataaa cactgtagag ttttcctatt atgtaaatga tatacagaaa atatttttct
     8101 atgaacagaa ggttaaaact gttaacttta atttcattgc ttaaaaggga taaaacaata
     8161 tttgtatgtc tttcatgctg taaagaaaat gaatgtatct ttcaaatgtt agagtcatta
     8221 cttgattgta agtatatgtg tttttaaaaa tctgtaaagg gttgaaaaga agagtattac
     8281 aagtcattat gtaagacgca atgttggaag aaatggaatt tcattataaa tgagcagtca
     8341 ctatcaaagc atatttcagt atagtgcata ttcattttca cattgctttg ttttatctct
     8401 agaaatgttt cttaaaaatt gtgtatactg ttttgggtat acactaattg gtttctacac
     8461 ttgtgtgtta ggctcagtgt gctgctgcat gtgtctacca tggggaaaag ttaccaagtt
     8521 ttgtcaatgt cgaagccacc aatgggggca tcattgttag aatgtgaaac ccatgcctag
     8581 gagccactgc agcaactctg tgcagaggcc tctgactgtg ctaatgtgtt tcccttttta
     8641 tcttcaatga catggatagt aagactactg ggcccaactc tcctgacttg tggtggtttg
     8701 tatgcttaca actttattca gctagtgccc gtaggtgtga atgatttgtt cattagctct
     8761 ttaaatctag tatttatcag ttattaaact tgatgaaaat tgggaattca ttgttttgac
     8821 acttttctag ccatccatac taattttaac tcatcatgat ggaccctgaa caaccaaaaa
     8881 gtgatccctg gttagtgtca gatttcctct accccagcat ttacaaggtt gactgatgac
     8941 ttagaagttg cattgttaaa taaagtcact gccaaggatc atgaaggagg tagctttctc
     9001 taaactttgg cccagagagg ctgcttcctg gttccctaga tggactaaat atctgctgtg
     9061 tgtcttcata tcctctatag tcacaattag gcctagttta cctcttaaaa atttttttgt
     9121 tttccactta tatttgcctt cctggggaag gaagattcaa cccaattcta tgattctctg
     9181 gattcatttt tccaagtttt tcaatgagtt agtgagattc ctcattcatg aatcctgtag
     9241 agtgtgtcct tttccagtgc taaaattgat ttcaaatagc actttatttc atgcttacta
     9301 ctgatttaat ttatacatta aaaatatcta tcctaggaat tttgtaaata cagaaaagca
     9361 attgattagt agtaaagttt attagattgg ccccaagttt aaatgcttta taatgatctc
     9421 ttgatagctt ctttgatatt taagaggtaa cctatgtgat tgaagctctg ccattttcct
     9481 gtaatctgtg tagtacagtg gaggctggcc cagctggctg tattgctgga cttacttctc
     9541 tcagctagct tcagccaagc ttggttgcta aaactgttga tctgctctgc attttgtgga
     9601 catgacatga atgtttggaa agctgttttt tgtcagtgta gtacctagag attcagtaga
     9661 tgctgcacca ccagttcata gtttatatgg aagacaaagg acagaattta tgacataaca
     9721 gtttctgtta agctgttttc atattctgcc aggacagtat atctgctgta aaaaaaataa
     9781 aagttgtcta ccctagtggt gcccagcatc agaacacacc aattataaac catgctgtga
     9841 gcttttcaaa taagaaaggc tggtccttgt tttctatagt gcaggttaac tttaggactg
     9901 atggcttata cttatcagta ctattttaaa cgttagctta aaaattattt ttatgtagag
     9961 ggtattttaa tttgggaact ttcttttctt gtaataggtg ctatatgtaa atatggagtg
    10021 agaatttgct tcattaaagg tctagcttat ttccttatta aggtattttt catttctgtt
    10081 tccatttcat ggtttgtact aaactaatag cagaatgaat tagtccctta aggctgtaac
    10141 taccttttct cccagttgta caaaaatatc tccattcggt ttcatctcag attaagaggc
    10201 aaagaagcta agaatgaaaa caaaatgcat aagcttgaat ttggtcaaca ctggactatt
    10261 tgaaatgatc actgtgtatt tgtcactgca gtttactgtg tctgaaaggc attgtgtgtg
    10321 tgtcttaatt tcagtgaaaa tcagaattcc tgccattcat gtttaaacaa gtcacacata
    10381 gcaacagtga acaggataaa aatgcgggtt tgcattgaaa ccgttttagt cctaacctca
    10441 atttatatta tgcaaaacac atttacagac attttgttgg ttatgtttca ttttgattta
    10501 gtacttgttc aggtacaaat tcgaaaagaa aacaatagct gttaatgttc gattgagaaa
    10561 taaagatcct cgttagtaac ctaa
//
