LOCUS       NM_001013111            2162 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus protein tyrosine phosphatase, non-receptor type
            18 (Ptpn18), mRNA.
ACCESSION   NM_001013111 XM_217373
VERSION     NM_001013111.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2162)
  AUTHORS   Cui,W., Dai,X., Marcho,C., Han,Z., Zhang,K., Tremblay,K.D. and
            Mager,J.
  TITLE     Towards Functional Annotation of the Preimplantation Transcriptome:
            An RNAi Screen in Mammalian Embryos
  JOURNAL   Sci Rep 6, 37396 (2016)
   PUBMED   27869233
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2162)
  AUTHORS   Wang,H.M., Xu,Y.F., Ning,S.L., Yang,D.X., Li,Y., Du,Y.J., Yang,F.,
            Zhang,Y., Liang,N., Yao,W., Zhang,L.L., Gu,L.C., Gao,C.J., Pang,Q.,
            Chen,Y.X., Xiao,K.H., Ma,R., Yu,X. and Sun,J.P.
  TITLE     The catalytic region and PEST domain of PTPN18 distinctly regulate
            the HER2 phosphorylation and ubiquitination barcodes
  JOURNAL   Cell Res 24 (9), 1067-1090 (2014)
   PUBMED   25081058
REFERENCE   3  (bases 1 to 2162)
  AUTHORS   Huang,K., Sommers,C.L., Grinberg,A., Kozak,C.A. and Love,P.E.
  TITLE     Cloning and characterization of PTP-K1, a novel nonreceptor protein
            tyrosine phosphatase highly expressed in bone marrow
  JOURNAL   Oncogene 13 (7), 1567-1573 (1996)
   PUBMED   8875997
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Mar 4, 2021 this sequence version replaced NM_001013111.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22582416.468525.1,
                                           SRR22582424.545323.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMEA5760393
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-109               JAXUCZ010000009.1  44168297-44168405
            110-218             JAXUCZ010000009.1  44171312-44171420
            219-295             JAXUCZ010000009.1  44171695-44171771
            296-391             JAXUCZ010000009.1  44171856-44171951
            392-430             JAXUCZ010000009.1  44172051-44172089
            431-499             JAXUCZ010000009.1  44179864-44179932
            500-562             JAXUCZ010000009.1  44181260-44181322
            563-705             JAXUCZ010000009.1  44181626-44181768
            706-772             JAXUCZ010000009.1  44182877-44182943
            773-850             JAXUCZ010000009.1  44183034-44183111
            851-940             JAXUCZ010000009.1  44183205-44183294
            941-1029            JAXUCZ010000009.1  44183477-44183565
            1030-1235           JAXUCZ010000009.1  44184204-44184409
            1236-1310           JAXUCZ010000009.1  44184775-44184849
            1311-2162           JAXUCZ010000009.1  44185034-44185885
FEATURES             Location/Qualifiers
     source          1..2162
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q21"
     gene            1..2162
                     /gene="Ptpn18"
                     /gene_synonym="PTP20"
                     /note="protein tyrosine phosphatase, non-receptor type 18"
                     /db_xref="GeneID:301333"
                     /db_xref="RGD:1311586"
     exon            1..109
                     /gene="Ptpn18"
                     /gene_synonym="PTP20"
                     /inference="alignment:Splign:2.1.0"
     CDS             17..1378
                     /gene="Ptpn18"
                     /gene_synonym="PTP20"
                     /EC_number="3.1.3.48"
                     /note="protein tyrosine phosphatase 20"
                     /codon_start=1
                     /product="tyrosine-protein phosphatase non-receptor type
                     18"
                     /protein_id="NP_001013129.2"
                     /db_xref="GeneID:301333"
                     /db_xref="RGD:1311586"
                     /translation="MSRQSDLVRSFLEQQEARDHREGAILAREFSDIKARSVAWKTEG
                     VCSTKAGSQQGNSKKNRYKDVVPYDETRVILSLLQEEGHGDYINANFIRGTDGSQAYI
                     ATQGPLPHTLLDFWRLVWEFGVKVILMACQETENGRRKCERYWAQEREPLQAGPFCIT
                     LTKETALTADITLRTLQVTFQKESRPVHQLQYMSWPDHGVPSSSDHILTMVEEARCLQ
                     GLGPGPLCVHCSAGCGRTGVLCAVDYVRQLLLTQTIPPNFSLFEVVLEMRKQRPAAVQ
                     TEEQYRFLYHTVAQLFSRTLQNNSPLYQNLKENRAPICKDSSSLRTSSALPATSRPLG
                     GVLRSISVPGPPTLPMADTYAVVQKRGAPAGTGPGTRAPNSTDTPIYSQVAPRIQRPV
                     SHTENAQGTTALGRVPADENPSGPDAYEEVTDGAQTGGLGFNLRIGRPKGPRDPPAEW
                     TRV"
     exon            110..218
                     /gene="Ptpn18"
                     /gene_synonym="PTP20"
                     /inference="alignment:Splign:2.1.0"
     exon            219..295
                     /gene="Ptpn18"
                     /gene_synonym="PTP20"
                     /inference="alignment:Splign:2.1.0"
     exon            296..391
                     /gene="Ptpn18"
                     /gene_synonym="PTP20"
                     /inference="alignment:Splign:2.1.0"
     exon            392..430
                     /gene="Ptpn18"
                     /gene_synonym="PTP20"
                     /inference="alignment:Splign:2.1.0"
     exon            431..499
                     /gene="Ptpn18"
                     /gene_synonym="PTP20"
                     /inference="alignment:Splign:2.1.0"
     exon            500..562
                     /gene="Ptpn18"
                     /gene_synonym="PTP20"
                     /inference="alignment:Splign:2.1.0"
     exon            563..705
                     /gene="Ptpn18"
                     /gene_synonym="PTP20"
                     /inference="alignment:Splign:2.1.0"
     exon            706..772
                     /gene="Ptpn18"
                     /gene_synonym="PTP20"
                     /inference="alignment:Splign:2.1.0"
     exon            773..850
                     /gene="Ptpn18"
                     /gene_synonym="PTP20"
                     /inference="alignment:Splign:2.1.0"
     exon            851..940
                     /gene="Ptpn18"
                     /gene_synonym="PTP20"
                     /inference="alignment:Splign:2.1.0"
     exon            941..1029
                     /gene="Ptpn18"
                     /gene_synonym="PTP20"
                     /inference="alignment:Splign:2.1.0"
     exon            1030..1235
                     /gene="Ptpn18"
                     /gene_synonym="PTP20"
                     /inference="alignment:Splign:2.1.0"
     exon            1236..1310
                     /gene="Ptpn18"
                     /gene_synonym="PTP20"
                     /inference="alignment:Splign:2.1.0"
     exon            1311..2162
                     /gene="Ptpn18"
                     /gene_synonym="PTP20"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgagcgggt tgcagtatga gtcgccaatc ggacctagtg aggagcttct tggagcagca
       61 ggaggcccgg gaccaccggg agggggcaat cctcgcccgt gagttcagcg acattaaggc
      121 ccgctcagtg gcctggaaga ctgaaggtgt gtgctccact aaagccggca gtcagcaggg
      181 aaactcaaag aagaaccgct acaaagacgt ggtaccgtat gatgagacga gagtcatcct
      241 ttccctgctc caggaggaag gacacggaga ttacattaat gccaacttca tccggggcac
      301 agatggaagc caggcctaca ttgcgacgca aggacccctg cctcacactc tgttggactt
      361 ctggcgcctg gtttgggagt ttggagtcaa ggtgatcttg atggcctgtc aggagacaga
      421 aaatggacgg aggaagtgtg aacgctactg ggcccaggag cgggagcctc tacaggccgg
      481 gcctttctgc atcaccctga caaaggagac agcactgact gcggacatca ctctcaggac
      541 cctccaggtt acattccaga aggaatcccg tcctgtgcac cagctacagt acatgtcttg
      601 gccggaccac ggggttccca gcagttccga tcacattctc accatggtgg aggaggcccg
      661 ttgcctccaa ggacttggac ctggacccct ctgtgtccac tgcagtgctg gctgtggacg
      721 aacaggtgtc ttgtgtgctg ttgattacgt gaggcagttg cttctgactc agacaatccc
      781 gcccaatttc agcctctttg aagtggtcct ggagatgcgg aaacagcgac ctgcagcggt
      841 gcagacagag gagcagtaca ggttcctgta ccacacagtg gctcagctat tctcccgcac
      901 tctccagaac aacagtcccc tctaccagaa cctcaaggag aaccgcgctc caatctgcaa
      961 ggactcctcg tccctcagga cctcctcagc cctgcctgcc acatcccgcc cactgggtgg
     1021 ggttctcagg agcatctcgg tgcctgggcc accgaccctt cccatggctg acacttacgc
     1081 tgtggtgcag aagcgtggcg ctccggcagg cacagggccg gggacgcggg cgcccaacag
     1141 cacggacacc ccgatctaca gccaggtggc tccacgtatc cagcggcccg tgtcacacac
     1201 cgaaaacgcg caggggacaa cggcactggg ccgagttcct gcggatgaaa acccttccgg
     1261 gcctgatgcc tatgaggaag taacagatgg agcgcagact ggtgggctag gcttcaactt
     1321 gcgcattgga agacctaaag ggccacggga tcctccagca gagtggacac gggtgtaatg
     1381 agtgctgtac cagttccagc ctatcactca gtggtggctg ggcgactgca acccccatgc
     1441 tgctgtgtgc tgtcttatgt atgagtggga ctcatgggcc tgaatcaaaa taaaagtttc
     1501 tcagggtaga aaaaaacaaa tagggacttt ggccagtggt tatagcagtc aaagccaggg
     1561 gctaggaggg gtaagtgggg gaggtggtgg atctactctg agaaagttta ggaaagcaca
     1621 tcaagagtga gcatcgccac tcttctcccc atacacctac tggaaagtgc accccagaca
     1681 gagtcctaac ttgacagtgc acctcagaca ggtgcctacc tggatggaca tgctggccct
     1741 acagctagag acatgtctaa ttagatcctc atgtaaactt gcaatgagct agaaagatct
     1801 ccgtctggtc agggaaatgg atcacctagt caggtaaata gtgtgccatc cagaagacag
     1861 aactgcaaga taccgtcttt ctcaaaatgg aagaaaatag atcctcaaga ataaatgtat
     1921 gtacaatgct ctacgccctg atcctgccct gcctcactgc cataatgtca caaacaagtc
     1981 agggtctata tgacagttgt tcatctagtc agtcctgact gtggcctctg caggctcaga
     2041 tagtgccttc tgcagactct tggaatgccc gtcttgaact tgatgaaagc ttctaccggg
     2101 aacttgcaaa catcattaaa attattaatg tagaattcaa taaagagtgg gtcaaaaact
     2161 ca
//
