LOCUS       NM_001114405            1353 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus protein tyrosine phosphatase 4A3 (Ptp4a3), mRNA.
ACCESSION   NM_001114405 XM_001069043 XM_001069094 XM_343259
VERSION     NM_001114405.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1353)
  AUTHORS   Zimmerman MW, McQueeney KE, Isenberg JS, Pitt BR, Wasserloos KA,
            Homanics GE and Lazo JS.
  TITLE     Protein-tyrosine phosphatase 4A3 (PTP4A3) promotes vascular
            endothelial growth factor signaling and enables endothelial cell
            motility
  JOURNAL   J Biol Chem 289 (9), 5904-5913 (2014)
   PUBMED   24403062
REFERENCE   2  (bases 1 to 1353)
  AUTHORS   Lian S, Meng L, Liu C, Xing X, Song Q, Dong B, Han Y, Yang Y, Peng
            L, Qu L and Shou C.
  TITLE     PRL-3 activates NF-kappaB signaling pathway by interacting with
            RAP1
  JOURNAL   Biochem Biophys Res Commun 430 (1), 196-201 (2013)
   PUBMED   23178297
REFERENCE   3  (bases 1 to 1353)
  AUTHORS   Fouillade C, Baron-Menguy C, Domenga-Denier V, Thibault C, Takamiya
            K, Huganir R and Joutel A.
  TITLE     Transcriptome analysis for Notch3 target genes identifies Grip2 as
            a novel regulator of myogenic response in the cerebrovasculature
  JOURNAL   Arterioscler Thromb Vasc Biol 33 (1), 76-86 (2013)
   PUBMED   23117660
REFERENCE   4  (bases 1 to 1353)
  AUTHORS   Tarantino C, Paolella G, Cozzuto L, Minopoli G, Pastore L, Parisi S
            and Russo T.
  TITLE     miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic
            stem cells
  JOURNAL   FASEB J 24 (9), 3255-3263 (2010)
   PUBMED   20439489
REFERENCE   5  (bases 1 to 1353)
  AUTHORS   Guo K, Li J, Wang H, Osato M, Tang JP, Quah SY, Gan BQ and Zeng Q.
  TITLE     PRL-3 initiates tumor angiogenesis by recruiting endothelial cells
            in vitro and in vivo
  JOURNAL   Cancer Res 66 (19), 9625-9635 (2006)
   PUBMED   17018620
  REMARK    GeneRIF: PRL-3 protein is expressed in fetal heart, developing
            blood vessels, and pre-erythrocytes but not in their mature
            counterparts.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC159432.1.
            
            On Feb 24, 2008 this sequence version replaced NM_001114405.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC159432.1, CB798463.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132264, SAMD00132266
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1353
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..1353
                     /gene="Ptp4a3"
                     /note="protein tyrosine phosphatase 4A3"
                     /db_xref="GeneID:362930"
                     /db_xref="RGD:1308687"
     exon            1..596
                     /gene="Ptp4a3"
                     /inference="alignment:Splign:2.1.0"
     CDS             492..1013
                     /gene="Ptp4a3"
                     /EC_number="3.1.3.48"
                     /note="protein tyrosine phosphatase type IVA, member 3"
                     /codon_start=1
                     /product="protein tyrosine phosphatase type IVA 3"
                     /protein_id="NP_001107877.1"
                     /db_xref="GeneID:362930"
                     /db_xref="RGD:1308687"
                     /translation="MARMNRPAPVEVSYRHMRFLITHNPSNATLSTFIEDLKKYGATT
                     VVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLLKAKFYNDPGSCVAV
                     HCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRF
                     KDPHTHKTRCCVM"
     exon            597..689
                     /gene="Ptp4a3"
                     /inference="alignment:Splign:2.1.0"
     exon            690..820
                     /gene="Ptp4a3"
                     /inference="alignment:Splign:2.1.0"
     exon            821..895
                     /gene="Ptp4a3"
                     /inference="alignment:Splign:2.1.0"
     exon            896..1328
                     /gene="Ptp4a3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgctggggc ccaactctga ccaaagggga cactcactcc tctatccacc gatgcagaga
       61 gggtgtctcc agcgacagcc ccatcgagga cactgctctg cggccagagt caccaacccc
      121 aagttctcgt tgctcgtttt ttttggttgt tgttattttt atttttgcat cctcctaact
      181 actccactct gagggacagg accttggagc tgcccatctt gctgcggggt gggggagggg
      241 tgtgtttgtt tctttttctt ttcttttttt tttttagaat tggggttttt tggaatcatc
      301 caccaccagg cagtttcctc tccctctccc aagttatttg cacaatattt gtgcggggtg
      361 taggggcgag gttttaagaa gtcttttctt ttcggacaag cacggggatc tcactggact
      421 tggtgtgggg gcctggggga ccccccgtgc agcccttgct ggctagtcct ctctgggtcc
      481 ccggaggagg catggcccgc atgaaccggc ctgcacctgt ggaggtgagc taccgacaca
      541 tgcgtttcct catcacccac aaccccagca atgccaccct cagcacgttc atcgaggacc
      601 tgaagaagta tggggctacc actgtggtgc gtgtgtgcga agtgacctat gacaagaccc
      661 ctctggagaa ggacggcatc actgttgtgg actggccctt tgatgatggg gcgccccctc
      721 ctggcaaggt ggtagaggac tggctgagcc tgctgaaggc caagttctac aatgacccgg
      781 gcagctgcgt agctgtgcac tgtgtggcgg gcctgggaag ggctccagtg ctcgtggctc
      841 tcgctctcat cgagagtggg atgaagtacg aggatgccat ccagttcatc cgacagaagc
      901 gccgtggggc catcaacagc aagcagctca cctacctgga gaagtaccgg cctaagcaga
      961 gactgagatt caaagaccca cacacgcaca agaccagatg ctgcgtcatg tagtgcgggt
     1021 tctggctctg tacgccctgt actccattac atcagggtct aaggagtcca acggctgtgt
     1081 gcgttcctgc tctgtcccca tctgtgccca cggctgtctt tctgaggccg tccctggacc
     1141 ttctgccagt cctgtccaac ccctccaccc actgcccggg cctcttcccc ctggcctgtg
     1201 tatcgcaggt gggctctttt taaccactgg gccgagagcc tcagcggcgg cgccctcacc
     1261 ctcacctttc tccagcacct ttgttaccag gtgctctgga ctctcaaggc aataaatcag
     1321 gagctgtgaa aaaaaaaaaa aaaaaaaaaa aaa
//
