LOCUS       NM_031975               1154 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus parathymosin (Ptms), mRNA.
ACCESSION   NM_031975 XM_001062784
VERSION     NM_031975.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1154)
  AUTHORS   Andreev,D.E., O'Connor,P.B., Zhdanov,A.V., Dmitriev,R.I.,
            Shatsky,I.N., Papkovsky,D.B. and Baranov,P.V.
  TITLE     Oxygen and glucose deprivation induces widespread alterations in
            mRNA translation within 20 minutes
  JOURNAL   Genome Biol 16 (1), 90 (2015)
   PUBMED   25943107
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1154)
  AUTHORS   Trompeter,H.I. and Soling,H.D.
  TITLE     Cloning and characterisation of a gene encoding the 11.5 kDa
            zinc-binding protein (parathymosin-alpha)
  JOURNAL   FEBS Lett 298 (2-3), 245-248 (1992)
   PUBMED   1544455
REFERENCE   3  (bases 1 to 1154)
  AUTHORS   Brand,I.A. and Heinickel,A.
  TITLE     Key enzymes of carbohydrate metabolism as targets of the 11.5-kDa
            Zn(2+)-binding protein (parathymosin)
  JOURNAL   J Biol Chem 266 (31), 20984-20989 (1991)
   PUBMED   1834654
REFERENCE   4  (bases 1 to 1154)
  AUTHORS   Trompeter,H.I., Brand,I.A. and Soling,H.D.
  TITLE     The primary sequence of the PFK-1 inactivating zinc-binding protein
            as deduced from cDNA sequencing. Identity of the zinc-binding
            protein with rat parathymosin
  JOURNAL   FEBS Lett 253 (1-2), 63-66 (1989)
   PUBMED   2759245
REFERENCE   5  (bases 1 to 1154)
  AUTHORS   Panneerselvam,C., Clinton,M., Wellner,D. and Horecker,B.L.
  TITLE     Bovine parathymosin: amino acid sequence and comparison with rat
            parathymosin
  JOURNAL   Biochem Biophys Res Commun 155 (2), 539-545 (1988)
   PUBMED   3421960
REFERENCE   6  (bases 1 to 1154)
  AUTHORS   Frangou-Lazaridis,M., Clinton,M., Goodall,G.J. and Horecker,B.L.
  TITLE     Prothymosin alpha and parathymosin: amino acid sequences deduced
            from the cloned rat spleen cDNAs
  JOURNAL   Arch Biochem Biophys 263 (2), 305-310 (1988)
   PUBMED   3377505
REFERENCE   7  (bases 1 to 1154)
  AUTHORS   Komiyama,T., Pan,L.X., Haritos,A.A., Wideman,J.W., Pan,Y.C.,
            Chang,M., Rogers,I. and Horecker,B.L.
  TITLE     The primary structure of rat parathymosin
  JOURNAL   Proc Natl Acad Sci U S A 83 (5), 1242-1245 (1986)
   PUBMED   3456585
REFERENCE   8  (bases 1 to 1154)
  AUTHORS   Haritos,A.A., Salvin,S.B., Blacher,R., Stein,S. and Horecker,B.L.
  TITLE     Parathymosin alpha: a peptide from rat tissues with structural
            homology to prothymosin alpha
  JOURNAL   Proc Natl Acad Sci U S A 82 (4), 1050-1053 (1985)
   PUBMED   3856246
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB801232.1, BC167753.1 and BI281491.1.
            
            On Aug 1, 2012 this sequence version replaced NM_031975.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC167753.1, X16481.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132296, SAMD00132301
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                CB801232.1         1-10
            11-1136             BC167753.1         1-1126
            1137-1154           BI281491.1         1-18                c
FEATURES             Location/Qualifiers
     source          1..1154
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..1154
                     /gene="Ptms"
                     /gene_synonym="ZnBP"
                     /note="parathymosin"
                     /db_xref="GeneID:83801"
                     /db_xref="RGD:621529"
     exon            1..377
                     /gene="Ptms"
                     /gene_synonym="ZnBP"
                     /inference="alignment:Splign:2.1.0"
     CDS             333..641
                     /gene="Ptms"
                     /gene_synonym="ZnBP"
                     /note="zinc-binding 11.5 kDa protein; zinc binding
                     protein"
                     /codon_start=1
                     /product="parathymosin"
                     /protein_id="NP_114181.1"
                     /db_xref="GeneID:83801"
                     /db_xref="RGD:621529"
                     /translation="MSEKSVEAAAELSAKDLKEKKDKVEEKAGRKERKKEVVEEEENG
                     AEEEEEETAEDGEDDDEGDEEDEEEEEEEDEGPVRKRTAEEEDEADPKRQKTENGASA
                     "
     exon            378..449
                     /gene="Ptms"
                     /gene_synonym="ZnBP"
                     /inference="alignment:Splign:2.1.0"
     exon            450..528
                     /gene="Ptms"
                     /gene_synonym="ZnBP"
                     /inference="alignment:Splign:2.1.0"
     exon            529..590
                     /gene="Ptms"
                     /gene_synonym="ZnBP"
                     /inference="alignment:Splign:2.1.0"
     exon            591..1138
                     /gene="Ptms"
                     /gene_synonym="ZnBP"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1108..1113
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ptms"
                     /gene_synonym="ZnBP"
     polyA_site      1129
                     /gene="Ptms"
                     /gene_synonym="ZnBP"
     polyA_site      1138
                     /gene="Ptms"
                     /gene_synonym="ZnBP"
ORIGIN      
        1 gctggtcggc ggcagctctg ctggtgcggg ggcggcgagc aagaccgagc gaccgcgacc
       61 ggagcgtgcc ggccaccgcc cgcatcatcc tcctgcccgc cctccggacg gccgcagccc
      121 tgcgggtctc cgctccggac ccacccccgc cccaccccgc gcgcctctgc cgcctcttgc
      181 tgcgagccag cttgccgagc ggccgtcgct gccgctgccg ctgccgccgc cgccaccgcg
      241 ccaagttccg gccgcggcca ccttccgccg tccagggctc ctccgcctcg gccccgggac
      301 cccggctccc cgccagcccc ggccccggca ccatgtcgga gaagagcgtg gaggcagcgg
      361 ccgagctaag cgccaaggac ctgaaggaaa agaaggacaa ggtggaggag aaggctggcc
      421 ggaaagaacg gaagaaagaa gtagtggagg aggaggagaa tggagctgag gaggaggaag
      481 aagaaactgc tgaggatgga gaggatgatg atgaaggaga cgaagaagat gaggaggaag
      541 aggaggagga ggacgaaggc cccgtgcgga agagaactgc tgaagaggag gatgaagcgg
      601 atcccaagag gcagaagaca gaaaacgggg cgtcggcttg agcccctgcc cgtgggcttg
      661 gggatgggag gcccctcagg tcctggaggt ggggcaggaa cacacaaatc cagcccccct
      721 tctcctggct ccctgctctg gccctgcccc agagctgtga cccttgccct ttgacccagc
      781 ctctcatttc catctctcca gacactgctc cttcaccctc actgccacag gtccagcccc
      841 caacccgcct catccaagct ccccagccgg ccctcacttg ccctagcatt ccttgttctt
      901 ccctgccttc ctcaccatcg atctgttcca gtccttgcga agcctctcct tcccctctgc
      961 accccgagcc tctcagcctg cccttctctc tcctgcctga cccctgggtc tccctcagat
     1021 tccctcctct cagacagcgc caggccgggg tggggctggg gttggggcca agccccgaag
     1081 ctgccccctc ccctttttgt ataatttaat aaagaaacgg tcgcgcttct gtttttaaaa
     1141 aaaaaaaaaa aaaa
//
