LOCUS       XM_039093607            4076 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus protein tyrosine kinase 2 beta
            (Ptk2b), transcript variant X1, mRNA.
ACCESSION   XM_039093607
VERSION     XM_039093607.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051350.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039093607.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4076
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4076
                     /gene="Ptk2b"
                     /gene_synonym="CAK beta; CAKB; CAKbeta; Pyk2"
                     /note="protein tyrosine kinase 2 beta; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 3 mRNAs, 118 ESTs, 25 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 22 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:50646"
                     /db_xref="RGD:628758"
     CDS             302..3331
                     /gene="Ptk2b"
                     /gene_synonym="CAK beta; CAKB; CAKbeta; Pyk2"
                     /codon_start=1
                     /product="protein-tyrosine kinase 2-beta isoform X1"
                     /protein_id="XP_038949535.1"
                     /db_xref="GeneID:50646"
                     /db_xref="RGD:628758"
                     /translation="MSGVSEPLSRVKVGTLRPPEGPPEPMVVVPVDVEKEDVRILKVC
                     FYSNSFNPGKNFKLVKCTVQTEIQEIITSILLSGRIGPNIQLAECYGLRLKHMKSDEI
                     HWLHPQMTVGEVQDKYECLHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRN
                     DYMQRYASKVSEGMALQLGCLELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQM
                     QENLKPKQFRKMIQQTFQQYASLREEECVMKFFNTLAGFANIDQETYRCELIQGWNIT
                     VDLVIGPKGIRQLTSQDTKPTCLAEFKQIRSIRCLPLEETQAVLQLGIEGAPQSLSIK
                     TSSLAEAENMADLIDGYCRLQGEHKGSLIIHAKKDGEKRNSLPQIPTLNLESRRSHLS
                     ESCSIESDIYAEIPDETLRRPGGPQYGVAREDVVLNRILGEGFFGEVYEGVYTNHKGE
                     KINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIVMELYPYG
                     ELGHYLERNKNSLKVPTLVLYALQICKAMAYLESINCVHRDIAVRNILVASPECVKLG
                     DFGLSRYIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQ
                     PFFWLENKDVIGVLEKGDRLPKPELCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDI
                     YQMERDIAIEQERNARYRPPKILEPTAFQEPPPKPSRPKYKHPPQTNLLAPKLQFQVP
                     EGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMREEDFIRPSSREEAQQLWE
                     AEKIKMRQVLDRQQKQMVEDSQWLRREERCLDPMVYMNDKSPLTPEKEAGYTEFTGPP
                     QKPPRLGAQSIQPTANLDRTDDLVYHNVMTLVEAVLELKNKLSQLPPEEYVVVVKNVG
                     LNLRKLIGSVDDLLPSLPASSRTEIEGTQKLLNKDLAELINKMRLAQQNAVTSLSEDC
                     KRQMLTASHTLAVDAKNLLDAVDQAKVVANLAHPPAE"
ORIGIN      
        1 aagaggagag cagcaggggt gtggttaacg accgaaagga ggaggtgggt ggggggaaaa
       61 caacctgtca gcctcttact cagcctctgc cggctgagcc ttgcgtccta cctgctggcg
      121 gctgcactca ccttgcccag cccggagccc tggcccgagt ccgcgcctcg cccgaggaaa
      181 ccttaacgaa agagagctga tggacctgta ggccaaacac agcctctgct ccatgcaggg
      241 aagctggagt cacacttttt acaggactgc aatgtgctgg tcctagctgc agtctgagag
      301 gatgtccggg gtgtctgagc ccctgagccg tgtaaaagtg ggcactttgc gcccgcccga
      361 gggcccccca gagcccatgg tagtggtacc agtagacgtg gagaaggaag acgtgcgtat
      421 cctcaaggtc tgcttctaca gcaacagctt caacccaggg aagaacttca agcttgtcaa
      481 atgcacagtg cagacagaga tccaggagat catcacctcc atcctcctga gtgggcgaat
      541 agggcccaac atccagctgg ctgaatgcta tgggctgagg ctgaagcaca tgaagtcaga
      601 tgagatccac tggctgcacc cacagatgac tgtgggcgaa gtgcaggaca agtatgaatg
      661 tctacacgtg gaggctgagt ggaggtatga ccttcaaatc cgctatttgc cagaagactt
      721 catggagagc ctgaaagaag acaggactac actgctgtac ttttatcaac agctccggaa
      781 tgactacatg caacgctatg ccagcaaggt cagtgaaggc atggctctgc agctgggctg
      841 tctggagctc aggagattct tcaaggacat gccccacaat gcacttgaca aaaagtccaa
      901 ctttgaactc ctggaaaaag aagtcggtct ggacctgttt ttcccaaagc aaatgcagga
      961 aaacttaaag cccaagcagt tccggaagat gatccagcag accttccagc agtatgcatc
     1021 actccgggag gaagagtgtg tcatgaaatt cttcaatact ctggcaggct ttgccaacat
     1081 cgaccaggag acctatcgct gtgaactcat tcaagggtgg aacattactg tggacctggt
     1141 cattggccct aaaggcatcc gtcagctgac aagtcaagac acaaagccca cctgcctcgc
     1201 cgagttcaag cagatcagat ccatcaggtg cctccccttg gaagagaccc aggcagtact
     1261 gcagctgggc atcgagggtg ccccccagtc cttgtccatc aaaacctcgt ccctggcaga
     1321 ggctgagaac atggctgacc tcatagatgg ctactgcagg cttcaaggag agcataaagg
     1381 ctctctcatc attcatgcca agaaagatgg tgagaagagg aacagcctgc ctcagatccc
     1441 cacactaaac ctggagtctc ggcggtccca cctctcagaa agctgtagca tagagtcaga
     1501 catctatgca gagattcctg atgagaccct gcgaaggcca ggaggcccac agtatggtgt
     1561 tgcccgtgaa gatgtagttc ttaaccgcat tctgggtgaa ggcttcttcg gggaggtcta
     1621 cgaaggtgtc tacacgaacc ataaagggga aaaaattaat gtggccgtca agacctgtaa
     1681 gaaagattgt accctggaca acaaggagaa gttcatgagt gaggcagtga tcatgaagaa
     1741 tcttgaccac cctcacatcg tcaagctgat tggcatcatt gaagaggaac ccacatggat
     1801 cgtcatggaa ctgtatcctt atggggagct gggacactac ctggagcgaa ataaaaattc
     1861 cctgaaggta cccactctgg tcctgtacgc tctgcagata tgcaaagcca tggcctatct
     1921 ggagagcatc aactgtgtcc acagggatat tgctgtccgg aacatcctgg tggcctctcc
     1981 tgagtgtgtg aagctcgggg actttgggct ctcccggtac attgaggatg aggactatta
     2041 caaagcttcc gtgacccgtc tccccatcaa atggatgtcc cccgagtcca tcaactttcg
     2101 ccgctttaca accgccagtg acgtctggat gtttgctgta tgcatgtggg agatcctcag
     2161 ctttgggaag cagcctttct tctggcttga aaacaaggat gtcatcgggg tgctggagaa
     2221 aggggacagg ctgcctaagc ccgaactctg cccgcctgtc ctttacacac tcatgacccg
     2281 ctgctgggac tatgacccca gcgaccggcc ccgctttacg gagcttgtgt gcagtctcag
     2341 tgacatttat cagatggaga gggacattgc aatagaacaa gaaaggaacg ctcgttaccg
     2401 accccccaaa atattggagc ccactgcttt tcaggaaccc ccacccaagc ccagccggcc
     2461 caagtacaaa caccctccac agaccaatct gctggctcct aagctgcagt tccaggtccc
     2521 tgagggtctg tgtgccagct ctcctacact tacgagccct atggagtatc catctccagt
     2581 taactcgctg cacaccccgc ctctgcaccg acacaatgtc ttcaagcgcc acagcatgcg
     2641 ggaggaggac ttcatccggc ccagtagtcg agaagaggcc cagcagctct gggaggcaga
     2701 gaagatcaag atgaggcagg tcctagacag acagcagaag caaatggtgg aagattccca
     2761 gtggctgagg cgggaggaaa gatgcttgga cccgatggtt tatatgaatg acaagtcccc
     2821 actgacccca gagaaggagg ccggctacac ggagttcaca gggccccccc agaagccacc
     2881 acggctcggt gcacagtcca tccagcctac agccaacttg gacaggactg atgacctcgt
     2941 gtaccacaat gtcatgaccc tggtggaggc cgtgctggaa ctcaagaaca agctcagcca
     3001 gctgcctcct gaggagtatg tggtggtggt gaagaatgtg gggctgaacc tgcggaagct
     3061 catcggtagc gtggacgatc tcctaccctc cttgccagca tcttctagaa cagagattga
     3121 agggacccag aaactgctca acaaagacct ggcagagctc atcaacaaga tgaggttggc
     3181 tcagcagaac gctgtgacat ccctaagtga ggactgcaag cggcagatgc tcacagcatc
     3241 ccataccctg gctgtggatg ccaagaacct cctggatgct gtagaccaag ccaaggttgt
     3301 ggctaatctg gcccacccgc ctgcagagtg atcaagggag ggaccacctg cctgcatctt
     3361 ctgccccaac ctttcctgcc ttgcctttgg ttattggtct tctagggaaa gctgagaaga
     3421 gtcctcccct taccactttg cacgaccccc ctttccccaa cccaccccag actgtgctac
     3481 ttgggctaca tctggacaga aaggactctg ggcacagaca cggggtgggg tgacatagtt
     3541 cataggggta cttctgccag ccattccctc ctaccccagc ctgggttgct ggagcatcat
     3601 tggggtcata actgtacccc taccagccaa gatggctttc tgcatggaca tttgagagcc
     3661 agtatttctg tcctctttag ccctcaggga cccctgatac agaggggaca gagaggggtt
     3721 ttatttgtag agaagctggt gagatgagag ctgggcatgg ctctcttgta cagtgtacat
     3781 tggaatttat ttaatgtgag tttggcctgg acagacagcc atgggccaca gtccaggaac
     3841 aagctaatcc agccacaggg aagaagcaga gtcaggggtc agaatgggac ttcatgtcct
     3901 ccctgcgttt ctcttctccc tctttcctcc tcccctcttt tcttagtcct cctttttctc
     3961 ttcccccttt tcacatctgt tcctttcctc tctcacattt gtggagaaca tccatttacc
     4021 ttttctcttt ttgatctgtg gttgaattaa aatcattagc attcgctttg tggtta
//
