LOCUS       NM_001106129            3356 bp    mRNA    linear   ROD 19-SEP-2024
DEFINITION  Rattus norvegicus prostaglandin reductase 3 (Ptgr3), mRNA.
ACCESSION   NM_001106129 XM_001060611 XM_214526
VERSION     NM_001106129.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3356)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 3356)
  AUTHORS   Yu,Y.H., Chang,Y.C., Su,T.H., Nong,J.Y., Li,C.C. and Chuang,L.M.
  TITLE     Prostaglandin reductase-3 negatively modulates adipogenesis through
            regulation of PPARgamma activity
  JOURNAL   J Lipid Res 54 (9), 2391-2399 (2013)
   PUBMED   23821743
REFERENCE   3  (bases 1 to 3356)
  AUTHORS   Mizuno,Y., Kurochkin,I.V., Herberth,M., Okazaki,Y. and Schonbach,C.
  TITLE     Predicted mouse peroxisome-targeted proteins and their actual
            subcellular locations
  JOURNAL   BMC Bioinformatics 9 Suppl 12 (Suppl 12), S16 (2008)
   PUBMED   19091015
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474021.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_214526.4, XM_001060611.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CO558750.1, CV112474.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3356
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18q12.3"
     gene            1..3356
                     /gene="Ptgr3"
                     /gene_synonym="Zadh2"
                     /note="prostaglandin reductase 3"
                     /db_xref="GeneID:291403"
                     /db_xref="RGD:1309999"
     exon            1..276
                     /gene="Ptgr3"
                     /gene_synonym="Zadh2"
                     /inference="alignment:Splign:2.1.0"
     CDS             68..1201
                     /gene="Ptgr3"
                     /gene_synonym="Zadh2"
                     /EC_number="1.3.1.48"
                     /note="zinc-binding alcohol dehydrogenase
                     domain-containing protein 2; zinc binding alcohol
                     dehydrogenase, domain containing 2"
                     /codon_start=1
                     /product="prostaglandin reductase 3"
                     /protein_id="NP_001099599.1"
                     /db_xref="GeneID:291403"
                     /db_xref="RGD:1309999"
                     /translation="MLRLATAGARAIVDMSYARHFLDFQGSAIPRTMQKLVVTRLSPN
                     FHEAVTLRRDCPVPLPGDGDLLVRNRFVGINASDINYSAGRYDPSVKPPFDIGFEGIG
                     EVVALGLSASAKYTVGQAVAYVTPGSFAEYTVVPASIAIPMPSVKPEYLTLLVSGTTA
                     YISLKELGELSEGKKVLVTAAAGGTGQFAVQLSKLAKCHVVGTCSSDEKSAFLKSVGC
                     DRPINYRTEPVETVLKQEYPEGVDVVYESVGGAMFDLAVDALATKGRLIVIGFISGYQ
                     SPTGLSPVKAGALPAKLLKKSASLRGFFLNHYFDKYQAAMEHLLQLYTRGDLVCEVDL
                     GHLAPEGRFIGLESIFQAVDYMYSGKNIGKLVVELPHPVSSKL"
     exon            277..3356
                     /gene="Ptgr3"
                     /gene_synonym="Zadh2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcggccggg actgggcgcg acccggccca gcgtaggcgc aggagcgggc ggagccgatc
       61 gtgggcaatg ctgaggctgg cgaccgccgg ggcccgagcc atcgtggaca tgtcgtacgc
      121 ccgtcacttc ctggacttcc agggctccgc catcccccga actatgcaga agctggtggt
      181 aacccggctg agccctaact tccacgaggc cgtcaccctg cgccgggact gcccagtgcc
      241 gctccccggg gacggagacc tcctcgtccg gaaccgattc gttggtatta acgcatctga
      301 catcaactat tcagctggcc gctatgaccc atccgtgaag cccccctttg acataggttt
      361 tgaagggatt ggtgaggtgg tggccttagg tctctctgcc agtgctaagt acacagtggg
      421 ccaggctgtg gcttatgtga ctcccggttc ctttgccgag tatacagtgg tgcctgctag
      481 cattgcaatt cctatgcctt cagtgaaacc tgaatatctc accttgctgg ttagtggcac
      541 cactgcatac atcagcctga aagagcttgg agagctgtca gaagggaaga aagttttggt
      601 tacagcagcc gctgggggca caggtcagtt tgctgtgcag ctttcaaagt tagccaagtg
      661 ccatgttgtc ggaacctgct cctcagacga aaaatcagct tttctgaagt ctgttgggtg
      721 tgatcggcca atcaactaca gaacagagcc cgtggagaca gttctgaagc aggagtaccc
      781 tgaaggagtt gatgtagtct atgagtctgt tgggggagcc atgtttgacc tggccgtgga
      841 tgccttagcc accaaagggc gcttgatagt aattgggttt atctctggtt accaaagccc
      901 tacaggactt tcaccagtca aagcgggagc tttgccggcc aaactcctga agaagtcagc
      961 cagcctcagg ggtttcttcc tgaaccacta cttcgacaag taccaggctg ccatggaaca
     1021 cttgctacag ctgtacactc gtggggacct ggtgtgtgag gtggacctgg gacacctggc
     1081 cccagagggg aggttcattg gcctggagtc catatttcag gctgttgact atatgtactc
     1141 ggggaaaaat attgggaaac ttgttgttga attaccacac cctgtcagca gtaagctgtg
     1201 acccaacaga acaatgacaa aggtcaaagg agagaagtga attctccgtg ccttagaatg
     1261 aacttaatac ttcttaaaaa caaaaggaga gtgttaatga atcccccccc cccttccttg
     1321 ggggtgaaaa taacatgcct gaataaaagt tctctctata gcacaaggta aaacgtttac
     1381 attcgagtct tcagtcgtgg acggtcttgt tccaaatttt atttgttcca gagaagtaaa
     1441 ttaattcctg atgtgagacc tgatcgagtc agtatgttcc cgcttgatga gatttttaaa
     1501 tcagtcttca gatagctcac ccagtctcct ttgcatggga agcagccctc ttacctcagg
     1561 tatgtaccag gtgagaacgc agtggggtca gtgggcgttg aattctctca ccggcactgt
     1621 gcttagggag gagcctttcc ccactgtaag tcactaacca atcttctaaa tagacatttg
     1681 ggagagaatt caacaaattt agccttgtta ttggaaaagt gattcagcaa acagatgcgt
     1741 cttaaggaag aatatactgt ttgatgccct gaattcacat cctggttaga ctgtctgtgc
     1801 agaaaagaac tttctggtct agggagaatt tccaattaga aagttttggg agagaaagct
     1861 ataccttggg gagtgggggg actggaaacc agtgtgcaca gaggagaaag aaaactctgc
     1921 agtgcctctt cagtaaaggg ctcacatagt accaacacag caatcacaga agggcgctca
     1981 ctctggcagg tgaagggtta aaaggggggc acttcctgtc cccaaggggc aaatgccaca
     2041 cagctccaaa cacagtaggc acccaggtca tgtaaaaaaa aatcatatcc atttgcttct
     2101 cctcagaggc ttggtgtgga aagtgcactt ggtctctggt gacagacgtg gaatgaaagt
     2161 caggtgtcct gtgttgcttc tcggtgtttg agagaagtga gctctggtgt tgtgtcctgg
     2221 tgcagtcctg tctatcaccc tgcctactgc ttctcttcac accgcaccat agctggtgtg
     2281 cctgcccttc accttgggta tttttgtgct ggaatcaaaa ccccacagtg ccttcctaat
     2341 cgaaggtgaa gcctgtcaga ttattttccg ggtcttgggt ttcagcacat caaacgttct
     2401 caatgaatgg gaatgcaatt aggagagctc tgcaaaagtc ggggtggggt ggggggcagg
     2461 tttaattctt tccttgcatc tggggagcag agagatcctg tttctgaata gctgttagta
     2521 tctgttttac aagatttact catttccagg tacctaatgt agctgctagc atgcacgcac
     2581 aacaatacaa tttatatggt aaatggagcc aaataatggt atcactgagt gttatggccg
     2641 cactgaaggg aaatgtcacg gtaaatagcc accaaattat ggatcacgcc gaagtgtcac
     2701 aactacacta aagacaaata gcactagagg ctattgccac tgtgatgcct ctgagttatg
     2761 aagaagggta gcagcctgag aggggctctt tgtgtcctcg tcatagcaga gggttgctgg
     2821 tgcaggggac aagaaaggct cttccagtac ggtgcttagt tattaatctg tcccttttag
     2881 acctcgtctc ttgtaacagg ggagacctcg ccggctctct tgtatacaaa cataaccaac
     2941 agaggggggg ggaagggctt tatggatgtc cgtgtgctca ggaaatgact ggtaatggaa
     3001 aaaatgttgt aataaaataa tctaatcaaa gacgattatt aaatttaaca tagtatatgt
     3061 ctgaaaggct gagtcgcttg ctatgcagat agatgtgtga aatctcactg atgatgctct
     3121 ctccctctga aaaggcttga ggactgagga cattaccagc taaattgcct cttctgaact
     3181 gaagtgagtc ccggtttcct tcattttaat gggtgggtaa taaagatgaa agaccaacat
     3241 tttatctgat ggatccctta agctatggaa taaaaatgta ttttgttttg aggggaacat
     3301 actaaattca gatatgtaaa agtaaaattc gcacacccag gtttaaaata aaacat
//
